- Interaction partners
- Confidence
- Network
- Evidence types
- SpeciesHSAMMURNOCFAGGADRECINDMECELBTASCEATHSPOBSUECOPFADDISSOSSCMJAOSA
- In Gold st.
- ID Query gene
- ID Query ortholog
Log-likelihood ratio (LLR) | |
---|---|
Highly positive | |
Positive | |
Zero | |
Negative | |
Highly negative | |
Known coupling | |
This network | |
Other network |
-
- ENSG00000174405
- DNA ligase 4
- XRCC4
- X-ray repair cross comp…
- 1.000
- PPI
- PRKDC
- protein kinase, DNA-act…
- 0.999
- PPI
- THOC5
- THO complex 5
- 0.999
- PPI
- APLF
- aprataxin and PNKP like…
- 0.999
- PPI
- RBM5
- RNA binding motif prote…
- 0.997
- PPI
- SMC2
- structural maintenance …
- 0.995
- PPI
- PNKP
- polynucleotide kinase 3…
- 0.995
- PPI
- XRCC5
- X-ray repair cross comp…
- 0.995
- Metabolic
- MRE11
- MRE11 homolog, double s…
- 0.994
- PPI
- DCLRE1C
- DNA cross-link repair 1C
- 0.992
- PPI
- NHEJ1
- non-homologous end join…
- 0.989
- PPI
- WDR20
- WD repeat domain 20
- 0.989
- PPI
- CAP1
- cyclase associated acti…
- 0.989
- PPI
- PLOD1
- procollagen-lysine,2-ox…
- 0.982
- PPI
- COA7
- cytochrome c oxidase as…
- 0.982
- PPI
- GPANK1
- G-patch domain and anky…
- 0.978
- PPI
- ERCC4
- ERCC excision repair 4,…
- 0.976
- Metabolic
- TSFM
- Ts translation elongati…
- 0.969
- PPI
- SMC5
- structural maintenance …
- 0.969
- Metabolic
- NIFK
- nucleolar protein inter…
- 0.965
- Metabolic
- SMC3
- structural maintenance …
- 0.962
- Metabolic
- BTK
- Bruton tyrosine kinase
- 0.961
- PPI
- RAD50
- RAD50 double strand bre…
- 0.956
- Metabolic
- MAK16
- MAK16 homolog
- 0.954
- Complex
- TRIM32
- tripartite motif contai…
- 0.949
- PPI
- EIF4G3
- eukaryotic translation …
- 0.949
- PPI
- ATR
- ATR serine/threonine ki…
- 0.948
- Metabolic
- DPP3
- dipeptidyl peptidase 3
- 0.946
- PPI
- SNX3
- sorting nexin 3
- 0.940
- PPI
- XRCC6
- X-ray repair cross comp…
- 0.932
- Metabolic
ENSG00000174405
DNA ligase 4
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- Ensembl
- UniProt
- NCBI
SMC5
structural maintenance of chromosomes 5
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- Ensembl
- UniProt
- NCBI
SMC3
structural maintenance of chromosomes 3
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- Ensembl
- UniProt
- NCBI
TSFM
Ts translation elongation factor, mitochondrial
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- Ensembl
- UniProt
- NCBI
CAP1
cyclase associated actin cytoskeleton regulatory protein 1
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- Ensembl
- UniProt
- NCBI
ATR
ATR serine/threonine kinase
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- Ensembl
- UniProt
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PRKDC
protein kinase, DNA-activated, catalytic subunit
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- Ensembl
- UniProt
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ERCC4
ERCC excision repair 4, endonuclease catalytic subunit
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- Ensembl
- UniProt
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MRE11
MRE11 homolog, double strand break repair nuclease
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- Ensembl
- UniProt
- NCBI
XRCC6
X-ray repair cross complementing 6
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- Ensembl
- UniProt
- NCBI
SMC2
structural maintenance of chromosomes 2
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- Ensembl
- UniProt
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MAK16
MAK16 homolog
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- Ensembl
- UniProt
- NCBI
DCLRE1C
DNA cross-link repair 1C
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- Ensembl
- UniProt
- NCBI
APLF
aprataxin and PNKP like factor
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- Ensembl
- UniProt
- NCBI
EIF4G3
eukaryotic translation initiation factor 4 gamma 3
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- Ensembl
- UniProt
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XRCC4
X-ray repair cross complementing 4
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- Ensembl
- UniProt
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RBM5
RNA binding motif protein 5
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- Ensembl
- UniProt
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NIFK
nucleolar protein interacting with the FHA domain of MKI67
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- Ensembl
- UniProt
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TRIM32
tripartite motif containing 32
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- Ensembl
- UniProt
- NCBI
THOC5
THO complex 5
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- Ensembl
- UniProt
- NCBI
XRCC5
X-ray repair cross complementing 5
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- Ensembl
- UniProt
- NCBI
PNKP
polynucleotide kinase 3'-phosphatase
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- Ensembl
- UniProt
- A0A0D9SEV0
- A0A0D9SFD6
- A0A0D9SFL2
- A0A0D9SFU1
- A0A1B0GU66
- A0A1B0GVJ3
- A0A1B0GW17
- A0A1B0GW61
- A0A1W2PP58
- M0QX49
- M0QYH2
- M0QYI1
- M0R000
- M0R097
- M0R3C8
- Q96T60
- NCBI
NHEJ1
non-homologous end joining factor 1
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- Ensembl
- UniProt
- NCBI
DPP3
dipeptidyl peptidase 3
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- Ensembl
- UniProt
- NCBI
WDR20
WD repeat domain 20
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- Ensembl
- UniProt
- NCBI
GPANK1
G-patch domain and ankyrin repeats 1
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- Ensembl
- UniProt
- NCBI
PLOD1
procollagen-lysine,2-oxoglutarate 5-dioxygenase 1
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- Ensembl
- UniProt
- NCBI
RAD50
RAD50 double strand break repair protein
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- Ensembl
- UniProt
- A0A494BZW0
- A0A494BZX5
- A0A494BZX8
- A0A494C0Y7
- A0A494C122
- A0A494C1B7
- C9JNH8
- E7EN38
- E7ESD9
- E9PM98
- H7C0P8
- H7C0V2
- Q92878
- NCBI
BTK
Bruton tyrosine kinase
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- Ensembl
- UniProt
- NCBI
COA7
cytochrome c oxidase assembly factor 7 (putative)
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- Ensembl
- UniProt
- NCBI
SNX3
sorting nexin 3
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- Ensembl
- UniProt
- NCBI
Symbol | Identifier | Description | |||
---|---|---|---|---|---|
30
|
ENSG00000174405 | ENSG00000174405 | DNA ligase 4 | ||
| A0A0C4DGV9 P49917 | ||||
| 3981 | ||||
| Non-homologous end-joining |
Symbol | Identifier | Description | |||
---|---|---|---|---|---|
14
|
SMC5 | ENSG00000198887 | structural maintenance of chromosomes 5 | ||
| Q8IY18 | ||||
| 23137 | ||||
19
|
SMC3 | ENSG00000108055 | structural maintenance of chromosomes 3 | ||
| Q9UQE7 | ||||
| 9126 | ||||
| Oocyte meiosis Cell cycle | ||||
9
|
TSFM | ENSG00000123297 | Ts translation elongation factor, mitochondrial | ||
| A0A494C1D5 A0A494C1M9 C9JG32 C9JT21 F8VPA7 F8VS27 F8WCK2 P43897 | ||||
| 10102 | ||||
11
|
CAP1 | ENSG00000131236 | cyclase associated actin cytoskeleton regulatory protein 1 | ||
| Q01518 Q5T0R1 Q5T0R2 Q5T0R3 Q5T0R4 Q5T0R5 Q5T0R6 Q5T0R7 Q5T0R8 Q5T0R9 Q5T0S3 | ||||
| 10487 | ||||
14
|
ATR | ENSG00000175054 | ATR serine/threonine kinase | ||
| A0A590UJ01 D6RFJ6 D6RIG7 H0Y8R8 Q13535 | ||||
| 545 | ||||
| p53 signaling pathway Cell cycle | ||||
| Fanconi anemia pathway | ||||
12
|
PRKDC | ENSG00000253729 | protein kinase, DNA-activated, catalytic subunit | ||
| F5GX40 H0YG84 P78527 | ||||
| 5591 | ||||
| Cell cycle | ||||
| Non-homologous end-joining | ||||
12
|
ERCC4 | ENSG00000175595 | ERCC excision repair 4, endonuclease catalytic subunit | ||
| I3L4K0 I3NI48 Q92889 | ||||
| 2072 | ||||
| Fanconi anemia pathway Nucleotide excision repair | ||||
17
|
MRE11 | ENSG00000020922 | MRE11 homolog, double strand break repair nuclease | ||
| F5GXT0 F5H256 F5H742 F8W7U8 P49959 | ||||
| 4361 | ||||
| Non-homologous end-joining Homologous recombination | ||||
20
|
XRCC6 | ENSG00000196419 | X-ray repair cross complementing 6 | ||
| B1AHC9 P12956 | ||||
| 2547 | ||||
| Non-homologous end-joining | ||||
19
|
SMC2 | ENSG00000136824 | structural maintenance of chromosomes 2 | ||
| A0A0C4DGE5 O95347 Q5T821 | ||||
| 10592 | ||||
13
|
MAK16 | ENSG00000198042 | MAK16 homolog | ||
| H0YBV6 Q9BXY0 | ||||
| 84549 | ||||
10
|
DCLRE1C | ENSG00000152457 | DNA cross-link repair 1C | ||
| B3KSJ7 Q96SD1 X6R9W9 X6RCQ3 X6RJV5 | ||||
| 64421 | ||||
| Non-homologous end-joining | ||||
6
|
APLF | ENSG00000169621 | aprataxin and PNKP like factor | ||
| E9PRH6 F8WET0 Q8IW19 | ||||
| 200558 | ||||
3
|
EIF4G3 | ENSG00000075151 | eukaryotic translation initiation factor 4 gamma 3 | ||
| A0A0A0MSA7 A0A0U1RQK7 B1AN91 B1AN92 O43432 | ||||
| 8672 | ||||
| RNA transport | ||||
10
|
XRCC4 | ENSG00000152422 | X-ray repair cross complementing 4 | ||
| Q13426 | ||||
| 7518 | ||||
| Non-homologous end-joining | ||||
12
|
RBM5 | ENSG00000003756 | RNA binding motif protein 5 | ||
| C9J9P7 C9JFQ5 C9JR02 F8W910 F8WE23 H7BYM9 P52756 | ||||
| 10181 | ||||
14
|
NIFK | ENSG00000155438 | nucleolar protein interacting with the FHA domain of MKI67 | ||
| C9J6C5 C9J808 H7BZL0 Q9BYG3 | ||||
| 84365 | ||||
2
|
TRIM32 | ENSG00000119401 | tripartite motif containing 32 | ||
| Q13049 Q5JVY0 | ||||
| 22954 | ||||
| Ubiquitin mediated proteolysis | ||||
15
|
THOC5 | ENSG00000100296 | THO complex 5 | ||
| C9JCL9 C9JXG5 C9JXU6 F5GZF3 F8WCP5 F8WES8 H7C072 H7C441 Q13769 | ||||
| 8563 | ||||
| RNA transport | ||||
20
|
XRCC5 | ENSG00000079246 | X-ray repair cross complementing 5 | ||
| C9JZ81 H7C0H9 P13010 | ||||
| 7520 | ||||
| Non-homologous end-joining | ||||
11
|
PNKP | ENSG00000039650 | polynucleotide kinase 3'-phosphatase | ||
| A0A0D9SEV0 A0A0D9SFD6 A0A0D9SFL2 A0A0D9SFU1 A0A1B0GU66 A0A1B0GVJ3 A0A1B0GW17 A0A1B0GW61 A0A1W2PP58 M0QX49 M0QYH2 M0QYI1 M0R000 M0R097 M0R3C8 Q96T60 | ||||
| 11284 | ||||
3
|
NHEJ1 | ENSG00000187736 | non-homologous end joining factor 1 | ||
| C9JWV4 F8WEB8 G5E9Q8 H7C0G7 Q9H9Q4 | ||||
| 79840 | ||||
| Non-homologous end-joining | ||||
7
|
DPP3 | ENSG00000254986 | dipeptidyl peptidase 3 | ||
| E9PKK8 E9PNX5 E9PPK9 E9PQ14 E9PQF2 G3V180 G3V1D3 Q9NY33 | ||||
| 10072 | ||||
8
|
WDR20 | ENSG00000140153 | WD repeat domain 20 | ||
| A0A088AWN2 G3V5V2 H0YK31 H0YKE8 H0YNU0 Q8TBZ3 | ||||
| 91833 | ||||
1
|
GPANK1 | ENSG00000204438 | G-patch domain and ankyrin repeats 1 | ||
| A0A0A0MSL4 A0A0A0MSL5 F6QYZ9 O95872 | ||||
| 7918 | ||||
4
|
PLOD1 | ENSG00000083444 | procollagen-lysine,2-oxoglutarate 5-dioxygenase 1 | ||
| Q02809 Q5JXB7 Q5JXB8 | ||||
| 5351 | ||||
| Lysine degradation | ||||
18
|
RAD50 | ENSG00000113522 | RAD50 double strand break repair protein | ||
| A0A494BZW0 A0A494BZX5 A0A494BZX8 A0A494C0Y7 A0A494C122 A0A494C1B7 C9JNH8 E7EN38 E7ESD9 E9PM98 H7C0P8 H7C0V2 Q92878 | ||||
| 10111 | ||||
| Non-homologous end-joining Homologous recombination | ||||
4
|
BTK | ENSG00000010671 | Bruton tyrosine kinase | ||
| Q06187 Q5JY90 U3NG26 | ||||
| 695 | ||||
| Fc epsilon RI signaling pathway B cell receptor signaling pathway NF-kappa B signaling pathway | ||||
4
|
COA7 | ENSG00000162377 | cytochrome c oxidase assembly factor 7 (putative) | ||
| Q96BR5 | ||||
| 65260 | ||||
4
|
SNX3 | ENSG00000112335 | sorting nexin 3 | ||
| O60493 | ||||
| 8724 | ||||
| Endocytosis |
Search for enrichment of pathways or functional gene sets for your subnetwork genes | ||
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jSquid_subnetworks.xml | 275.47 KB | |
H.sapiens_subnetwork.tsv | 30.91 KB |