- Interaction partners
- Confidence
- Network
- Evidence types
- SpeciesHSAMMURNOCFAGGADRECINDMECELBTASCEATHSPOBSUECOPFADDISSOSSCMJAOSA
- In Gold st.
- ID Query gene
- ID Query ortholog
Log-likelihood ratio (LLR) | |
---|---|
Highly positive | |
Positive | |
Zero | |
Negative | |
Highly negative | |
Known coupling | |
This network | |
Other network |
-
- ENSG00000143799
- poly(ADP-ribose) polyme…
- XRCC5
- X-ray repair cross comp…
- 1.000
- PPI
- XRCC1
- X-ray repair cross comp…
- 1.000
- PPI
- XRCC6
- X-ray repair cross comp…
- 1.000
- PPI
- NBN
- nibrin
- 1.000
- PPI
- PARP2
- poly(ADP-ribose) polyme…
- 1.000
- PPI
- UHRF1
- ubiquitin like with PHD…
- 1.000
- PPI
- MRE11
- MRE11 homolog, double s…
- 1.000
- PPI
- RPA1
- replication protein A1
- 1.000
- PPI
- BANF1
- BAF nuclear assembly fa…
- 1.000
- PPI
- H2AX
- H2A.X variant histone
- 1.000
- PPI
- NCL
- nucleolin
- 1.000
- PPI
- HMGB1
- high mobility group box…
- 1.000
- PPI
- POLA1
- DNA polymerase alpha 1,…
- 1.000
- PPI
- DNMT1
- DNA methyltransferase 1
- 1.000
- PPI
- CBX5
- chromobox 5
- 1.000
- Complex
- APLF
- aprataxin and PNKP like…
- 1.000
- PPI
- CHFR
- checkpoint with forkhea…
- 1.000
- PPI
- TOP2B
- DNA topoisomerase II be…
- 1.000
- PPI
- CTCF
- CCCTC-binding factor
- 1.000
- PPI
- POLA2
- DNA polymerase alpha 2,…
- 1.000
- PPI
- PRKDC
- protein kinase, DNA-act…
- 1.000
- PPI
- H1-5
- H1.5 linker histone, cl…
- 1.000
- PPI
- RAD50
- RAD50 double strand bre…
- 1.000
- PPI
- EIF3L
- eukaryotic translation …
- 1.000
- Complex
- VPS35
- VPS35 retromer complex …
- 1.000
- Complex
- EZH2
- enhancer of zeste 2 pol…
- 1.000
- PPI
- MYBL2
- MYB proto-oncogene like…
- 1.000
- PPI
- TOP2A
- DNA topoisomerase II al…
- 1.000
- PPI
- CBX1
- chromobox 1
- 1.000
- Complex
- MACROH2A1
- macroH2A.1 histone
- 0.999
- PPI
ENSG00000143799
poly(ADP-ribose) polymerase 1
- Use as query
- Use pair as query
- Add to current query
- Ensembl
- UniProt
- NCBI
EZH2
enhancer of zeste 2 polycomb repressive complex 2 subunit
- Use as query
- Use pair as query
- Add to current query
- Ensembl
- UniProt
- NCBI
POLA2
DNA polymerase alpha 2, accessory subunit
- Use as query
- Use pair as query
- Add to current query
- Ensembl
- UniProt
- NCBI
BANF1
BAF nuclear assembly factor 1
- Use as query
- Use pair as query
- Add to current query
- Ensembl
- UniProt
- NCBI
MRE11
MRE11 homolog, double strand break repair nuclease
- Use as query
- Use pair as query
- Add to current query
- Ensembl
- UniProt
- NCBI
POLA1
DNA polymerase alpha 1, catalytic subunit
- Use as query
- Use pair as query
- Add to current query
- Ensembl
- UniProt
- NCBI
MYBL2
MYB proto-oncogene like 2
- Use as query
- Use pair as query
- Add to current query
- Ensembl
- UniProt
- NCBI
TOP2A
DNA topoisomerase II alpha
- Use as query
- Use pair as query
- Add to current query
- Ensembl
- UniProt
- NCBI
TOP2B
DNA topoisomerase II beta
- Use as query
- Use pair as query
- Add to current query
- Ensembl
- UniProt
- NCBI
APLF
aprataxin and PNKP like factor
- Use as query
- Use pair as query
- Add to current query
- Ensembl
- UniProt
- NCBI
RAD50
RAD50 double strand break repair protein
- Use as query
- Use pair as query
- Add to current query
- Ensembl
- UniProt
- A0A494BZW0
- A0A494BZX5
- A0A494BZX8
- A0A494C0Y7
- A0A494C122
- A0A494C1B7
- C9JNH8
- E7EN38
- E7ESD9
- E9PM98
- H7C0P8
- H7C0V2
- Q92878
- NCBI
RPA1
replication protein A1
- Use as query
- Use pair as query
- Add to current query
- Ensembl
- UniProt
- NCBI
DNMT1
DNA methyltransferase 1
- Use as query
- Use pair as query
- Add to current query
- Ensembl
- UniProt
- NCBI
NBN
nibrin
- Use as query
- Use pair as query
- Add to current query
- Ensembl
- UniProt
- NCBI
CBX5
chromobox 5
- Use as query
- Use pair as query
- Add to current query
- Ensembl
- UniProt
- NCBI
H2AX
H2A.X variant histone
- Use as query
- Use pair as query
- Add to current query
- Ensembl
- UniProt
- NCBI
XRCC6
X-ray repair cross complementing 6
- Use as query
- Use pair as query
- Add to current query
- Ensembl
- UniProt
- NCBI
NCL
nucleolin
- Use as query
- Use pair as query
- Add to current query
- Ensembl
- UniProt
- NCBI
PARP2
poly(ADP-ribose) polymerase 2
- Use as query
- Use pair as query
- Add to current query
- Ensembl
- UniProt
- NCBI
H1-5
H1.5 linker histone, cluster member
- Use as query
- Use pair as query
- Add to current query
- Ensembl
- UniProt
- NCBI
EIF3L
eukaryotic translation initiation factor 3 subunit L
- Use as query
- Use pair as query
- Add to current query
- Ensembl
- UniProt
- NCBI
VPS35
VPS35 retromer complex component
- Use as query
- Use pair as query
- Add to current query
- Ensembl
- UniProt
- NCBI
HMGB1
high mobility group box 1
- Use as query
- Use pair as query
- Add to current query
- Ensembl
- UniProt
- NCBI
XRCC1
X-ray repair cross complementing 1
- Use as query
- Use pair as query
- Add to current query
- Ensembl
- UniProt
- NCBI
MACROH2A1
macroH2A.1 histone
- Use as query
- Use pair as query
- Add to current query
- Ensembl
- UniProt
- NCBI
XRCC5
X-ray repair cross complementing 5
- Use as query
- Use pair as query
- Add to current query
- Ensembl
- UniProt
- NCBI
CTCF
CCCTC-binding factor
- Use as query
- Use pair as query
- Add to current query
- Ensembl
- UniProt
- NCBI
PRKDC
protein kinase, DNA-activated, catalytic subunit
- Use as query
- Use pair as query
- Add to current query
- Ensembl
- UniProt
- NCBI
UHRF1
ubiquitin like with PHD and ring finger domains 1
- Use as query
- Use pair as query
- Add to current query
- Ensembl
- UniProt
- NCBI
CBX1
chromobox 1
- Use as query
- Use pair as query
- Add to current query
- Ensembl
- UniProt
- NCBI
CHFR
checkpoint with forkhead and ring finger domains
- Use as query
- Use pair as query
- Add to current query
- Ensembl
- UniProt
- NCBI
Symbol | Identifier | Description | |||
---|---|---|---|---|---|
30
|
ENSG00000143799 | ENSG00000143799 | poly(ADP-ribose) polymerase 1 | ||
| P09874 Q5VX84 Q5VX85 | ||||
| 142 | ||||
| Apoptosis NF-kappa B signaling pathway | ||||
| Base excision repair |
Symbol | Identifier | Description | |||
---|---|---|---|---|---|
23
|
EZH2 | ENSG00000106462 | enhancer of zeste 2 polycomb repressive complex 2 subunit | ||
| E9PDH6 G3XAL2 Q15910 | ||||
| 2146 | ||||
| Lysine degradation | ||||
18
|
POLA2 | ENSG00000014138 | DNA polymerase alpha 2, accessory subunit | ||
| E9PIQ6 E9PQ99 H0YDR7 Q14181 | ||||
| 23649 | ||||
| DNA replication | ||||
21
|
BANF1 | ENSG00000175334 | BAF nuclear assembly factor 1 | ||
| E9PJJ8 O75531 | ||||
| 8815 | ||||
26
|
MRE11 | ENSG00000020922 | MRE11 homolog, double strand break repair nuclease | ||
| F5GXT0 F5H256 F5H742 F8W7U8 P49959 | ||||
| 4361 | ||||
| Non-homologous end-joining Homologous recombination | ||||
22
|
POLA1 | ENSG00000101868 | DNA polymerase alpha 1, catalytic subunit | ||
| A0A087WU64 A0A5F9ZHW2 A6NMQ1 P09884 | ||||
| 5422 | ||||
| DNA replication | ||||
16
|
MYBL2 | ENSG00000101057 | MYB proto-oncogene like 2 | ||
| P10244 | ||||
| 4605 | ||||
24
|
TOP2A | ENSG00000131747 | DNA topoisomerase II alpha | ||
| J3KTB7 J3QR57 P11388 | ||||
| 7153 | ||||
20
|
TOP2B | ENSG00000077097 | DNA topoisomerase II beta | ||
| E9PCY5 H7BZ82 Q02880 | ||||
| 7155 | ||||
9
|
APLF | ENSG00000169621 | aprataxin and PNKP like factor | ||
| E9PRH6 F8WET0 Q8IW19 | ||||
| 200558 | ||||
23
|
RAD50 | ENSG00000113522 | RAD50 double strand break repair protein | ||
| A0A494BZW0 A0A494BZX5 A0A494BZX8 A0A494C0Y7 A0A494C122 A0A494C1B7 C9JNH8 E7EN38 E7ESD9 E9PM98 H7C0P8 H7C0V2 Q92878 | ||||
| 10111 | ||||
| Non-homologous end-joining Homologous recombination | ||||
28
|
RPA1 | ENSG00000132383 | replication protein A1 | ||
| I3L2M5 I3L4R8 I3L524 P27694 | ||||
| 6117 | ||||
| DNA replication Fanconi anemia pathway Homologous recombination Mismatch repair Nucleotide excision repair | ||||
19
|
DNMT1 | ENSG00000130816 | DNA methyltransferase 1 | ||
| K7EIZ6 K7EJL0 K7EKC3 K7ELB1 K7EMU8 K7ENQ6 K7ENW7 K7EP77 K7ER10 K7ERQ1 P26358 | ||||
| 1786 | ||||
| Cysteine and methionine metabolism | ||||
9
|
NBN | ENSG00000104320 | nibrin | ||
| A0A087X1V5 A0A0C4DG07 E2QRP0 E5RGN7 E5RGR7 E5RGU1 O60934 | ||||
| 4683 | ||||
| Homologous recombination | ||||
26
|
CBX5 | ENSG00000094916 | chromobox 5 | ||
| F8VNY3 P45973 | ||||
| 23468 | ||||
26
|
H2AX | ENSG00000188486 | H2A.X variant histone | ||
| P16104 | ||||
| 3014 | ||||
24
|
XRCC6 | ENSG00000196419 | X-ray repair cross complementing 6 | ||
| B1AHC9 P12956 | ||||
| 2547 | ||||
| Non-homologous end-joining | ||||
19
|
NCL | ENSG00000115053 | nucleolin | ||
| C9J1H7 C9JLB1 C9JWL1 C9JYW2 H7BY16 P19338 | ||||
| 4691 | ||||
17
|
PARP2 | ENSG00000129484 | poly(ADP-ribose) polymerase 2 | ||
| E9PJ27 G3V167 H0YH02 Q9UGN5 | ||||
| 10038 | ||||
| Apoptosis | ||||
| Base excision repair | ||||
19
|
H1-5 | ENSG00000184357 | H1.5 linker histone, cluster member | ||
| P16401 | ||||
| 3009 | ||||
15
|
EIF3L | ENSG00000100129 | eukaryotic translation initiation factor 3 subunit L | ||
| B0QY89 B0QY90 C9JHP4 C9K0Q7 H0Y7E6 H7C133 H7C3A0 Q9Y262 | ||||
| 51386 | ||||
11
|
VPS35 | ENSG00000069329 | VPS35 retromer complex component | ||
| A0A1W2PP10 A0A3B3ITD4 H3BRJ7 I3L4S0 Q96QK1 | ||||
| 55737 | ||||
| Endocytosis | ||||
24
|
HMGB1 | ENSG00000189403 | high mobility group box 1 | ||
| P09429 Q5T7C4 | ||||
| 3146 | ||||
| Autophagy - animal Base excision repair | ||||
22
|
XRCC1 | ENSG00000073050 | X-ray repair cross complementing 1 | ||
| F5H8D7 M0QYS5 M0QZ96 M0R0D2 M0R1U8 P18887 | ||||
| 7515 | ||||
| Base excision repair | ||||
14
|
MACROH2A1 | ENSG00000113648 | macroH2A.1 histone | ||
| B4DJC3 D6RCF2 O75367 | ||||
| 9555 | ||||
28
|
XRCC5 | ENSG00000079246 | X-ray repair cross complementing 5 | ||
| C9JZ81 H7C0H9 P13010 | ||||
| 7520 | ||||
| Non-homologous end-joining | ||||
16
|
CTCF | ENSG00000102974 | CCCTC-binding factor | ||
| A0A2R8Y595 A0A2R8Y6C1 A0A2R8Y6Z6 A0A2R8YFL0 P49711 | ||||
| 10664 | ||||
13
|
PRKDC | ENSG00000253729 | protein kinase, DNA-activated, catalytic subunit | ||
| F5GX40 H0YG84 P78527 | ||||
| 5591 | ||||
| Cell cycle | ||||
| Non-homologous end-joining | ||||
19
|
UHRF1 | ENSG00000276043 | ubiquitin like with PHD and ring finger domains 1 | ||
| A0A087WTW0 A0A087WVR3 A0A087WWG9 Q96T88 | ||||
| 29128 | ||||
20
|
CBX1 | ENSG00000108468 | chromobox 1 | ||
| B5MD17 C9JWS9 J3KS05 K7ELA4 P83916 | ||||
| 10951 | ||||
3
|
CHFR | ENSG00000072609 | checkpoint with forkhead and ring finger domains | ||
| A0A087WUN4 A0A087X0W6 A0A096P6K8 F5GWH4 F5H375 F5H5P5 F5H829 Q96EP1 U3KPU9 | ||||
| 55743 |
Search for enrichment of pathways or functional gene sets for your subnetwork genes | ||
To use PathwAX, first use the button below to copy the subnetwork genes and then paste them in PathwAX | ||
- Use as query
- Add to current query
jSquid_subnetworks.xml | 306.46 KB | |
H.sapiens_subnetwork.tsv | 50.23 KB |