Found 1 of 1 query genes

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Query interactions

Interaction partners
Confidence
Network
MEX
PIN
SCL
PHP
MIR
TFB
PEX
GIN
DOM
QMS
GRG
Evidence types
HSA
MMU
RNO
CFA
GGA
DRE
CIN
DME
CEL
BTA
SCE
ATH
SPO
BSU
ECO
PFA
DDI
SSO
SSC
MJA
OSA
Species
In Gold st.

ID Query gene
ID Query ortholog

Log-likelihood ratio (LLR)
	Highly positive
	Positive
	Zero
	Negative
	Highly negative
Known coupling
	This network
	Other network

2. ENSG00000139154
3. AE binding protein 2
- 2. EZH2
  3. enhancer of zeste 2 pol…
  4. 1.000
  5. PPI
- 2. EED
  3. embryonic ectoderm deve…
  4. 1.000
  5. PPI
- 2. RBBP7
  3. RB binding protein 7, c…
  4. 1.000
  5. PPI
- 2. RBBP4
  3. RB binding protein 4, c…
  4. 1.000
  5. PPI
- 2. JARID2
  3. jumonji and AT-rich int…
  4. 1.000
  5. PPI
- 2. SUZ12
  3. SUZ12 polycomb repressi…
  4. 1.000
  5. PPI
- 2. MTF2
  3. metal response element …
  4. 0.999
  5. Complex
- 2. EZH1
  3. enhancer of zeste 1 pol…
  4. 0.998
  5. PPI
- 2. PHF19
  3. PHD finger protein 19
  4. 0.981
  5. Complex
- 2. THAP1
  3. THAP domain containing 1
  4. 0.975
  5. PPI
- 2. POLR2H
  3. RNA polymerase II subun…
  4. 0.969
  5. Complex
- 2. HMBOX1
  3. homeobox containing 1
  4. 0.967
  5. PPI
- 2. CCT5
  3. chaperonin containing T…
  4. 0.945
  5. Complex
- 2. LCOR
  3. ligand dependent nuclea…
  4. 0.943
  5. Complex
- 2. BRD2
  3. bromodomain containing 2
  4. 0.937
  5. Complex
- 2. BTRC
  3. beta-transducin repeat …
  4. 0.913
  5. PPI
- 2. ATXN3
  3. ataxin 3
  4. 0.912
  5. PPI
- 2. PHF1
  3. PHD finger protein 1
  4. 0.895
  5. Complex
- 2. FBXW11
  3. F-box and WD repeat dom…
  4. 0.861
  5. PPI
- 2. TUBA1C
  3. tubulin alpha 1c
  4. 0.807
  5. Complex
- 2. SETX
  3. senataxin
  4. 0.749
  5. Signaling
- 2. BLVRA
  3. biliverdin reductase A
  4. 0.748
  5. Complex
- 2. ICE1
  3. interactor of little el…
  4. 0.646
  5. PPI
- 2. APP
  3. amyloid beta precursor …
  4. 0.600
  5. PPI
- 2. H1-1
  3. H1.1 linker histone, cl…
  4. 0.572
  5. PPI
- 2. IVNS1ABP
  3. influenza virus NS1A bi…
  4. 0.533
  5. Complex
- 2. BCLAF1
  3. BCL2 associated transcr…
  4. 0.523
  5. Complex
- 2. EPOP
  3. elongin BC and polycomb…
  4. 0.509
  5. Complex
- 2. MYBBP1A
  3. MYB binding protein 1a
  4. 0.499
  5. Complex
- 2. PSMC1
  3. proteasome 26S subunit,…
  4. 0.440
  5. PPI

Subnetwork gene interactions

ENSG00000139154

AE binding protein 2

FunCoup

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Ensembl

ENSG00000139154

UniProt

NCBI

121536

EED

embryonic ectoderm development

FunCoup

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Ensembl

ENSG00000074266

UniProt

NCBI

8726

JARID2

jumonji and AT-rich interaction domain containing 2

FunCoup

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Ensembl

ENSG00000008083

UniProt

Q92833

NCBI

3720

MTF2

metal response element binding transcription factor 2

FunCoup

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Ensembl

ENSG00000143033

UniProt

Q9Y483

NCBI

22823

PHF19

PHD finger protein 19

FunCoup

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Ensembl

ENSG00000119403

UniProt

NCBI

26147

CCT5

chaperonin containing TCP1 subunit 5

FunCoup

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Ensembl

ENSG00000150753

UniProt

NCBI

22948

TUBA1C

tubulin alpha 1c

FunCoup

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Ensembl

ENSG00000167553

UniProt

NCBI

84790

LCOR

ligand dependent nuclear receptor corepressor

FunCoup

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Ensembl

ENSG00000196233

UniProt

NCBI

84458

EZH2

enhancer of zeste 2 polycomb repressive complex 2 subunit

FunCoup

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Ensembl

ENSG00000106462

UniProt

NCBI

2146

EZH1

enhancer of zeste 1 polycomb repressive complex 2 subunit

FunCoup

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Ensembl

ENSG00000108799

UniProt

NCBI

2145

POLR2H

RNA polymerase II subunit H

FunCoup

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Ensembl

ENSG00000163882

UniProt

NCBI

5437

RBBP7

RB binding protein 7, chromatin remodeling factor

FunCoup

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Ensembl

ENSG00000102054

UniProt

NCBI

5931

EPOP

elongin BC and polycomb repressive complex 2 associated protein

FunCoup

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Ensembl

ENSG00000273604

UniProt

A6NHQ4

NCBI

100170841

SUZ12

SUZ12 polycomb repressive complex 2 subunit

FunCoup

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Ensembl

ENSG00000178691

UniProt

NCBI

23512

SETX

senataxin

FunCoup

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Ensembl

ENSG00000107290

UniProt

NCBI

23064

RBBP4

RB binding protein 4, chromatin remodeling factor

FunCoup

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Ensembl

ENSG00000162521

UniProt

NCBI

5928

BLVRA

biliverdin reductase A

FunCoup

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Ensembl

ENSG00000106605

UniProt

NCBI

MYBBP1A

MYB binding protein 1a

FunCoup

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Ensembl

ENSG00000132382

UniProt

NCBI

10514

BRD2

bromodomain containing 2

FunCoup

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Ensembl

ENSG00000204256

UniProt

NCBI

6046

APP

amyloid beta precursor protein

FunCoup

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Ensembl

ENSG00000142192

UniProt

NCBI

PSMC1

proteasome 26S subunit, ATPase 1

FunCoup

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Ensembl

ENSG00000100764

UniProt

NCBI

5700

PHF1

PHD finger protein 1

FunCoup

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Ensembl

ENSG00000112511

UniProt

NCBI

5252

THAP1

THAP domain containing 1

FunCoup

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Ensembl

ENSG00000131931

UniProt

NCBI

55145

BTRC

beta-transducin repeat containing E3 ubiquitin protein ligase

FunCoup

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Ensembl

ENSG00000166167

UniProt

NCBI

8945

FBXW11

F-box and WD repeat domain containing 11

FunCoup

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Ensembl

ENSG00000072803

UniProt

NCBI

23291

BCLAF1

BCL2 associated transcription factor 1

FunCoup

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Ensembl

ENSG00000029363

UniProt

NCBI

9774

H1-1

H1.1 linker histone, cluster member

FunCoup

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Ensembl

ENSG00000124610

UniProt

Q02539

NCBI

3024

IVNS1ABP

influenza virus NS1A binding protein

FunCoup

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Ensembl

ENSG00000116679

UniProt

NCBI

10625

ICE1

interactor of little elongation complex ELL subunit 1

FunCoup

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Ensembl

ENSG00000164151

UniProt

NCBI

23379

ATXN3

ataxin 3

FunCoup

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Ensembl

ENSG00000066427

UniProt

NCBI

4287

HMBOX1

homeobox containing 1

FunCoup

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Ensembl

ENSG00000147421

UniProt

NCBI

79618

Query genes

		Identifier	Description
30	ENSG00000139154	ENSG00000139154	AE binding protein 2
		UniProt	F5GZR7 G5EA50 H0YH08 H7BYT4 Q6ZN18
		NCBI	121536

Subnetwork genes

		Identifier	Description
23	EED	ENSG00000074266	embryonic ectoderm development
		UniProt	A0A5F9ZI63 E9PJK2 E9PMU3 H0YEL4 O75530
		NCBI	8726
21	JARID2	ENSG00000008083	jumonji and AT-rich interaction domain containing 2
		UniProt	Q92833
		NCBI	3720
20	MTF2	ENSG00000143033	metal response element binding transcription factor 2
		UniProt	Q9Y483
		NCBI	22823
15	PHF19	ENSG00000119403	PHD finger protein 19
		UniProt	A0A087X169 B0QZ50 B0QZ51 B0QZ72 F5H8K3 Q5T6S3 X6RER8
		NCBI	26147
19	CCT5	ENSG00000150753	chaperonin containing TCP1 subunit 5
		UniProt	B7ZAR1 D6RIZ7 E7ENZ3 E9PCA1 H0Y914 H0Y958 P48643
		NCBI	22948
20	TUBA1C	ENSG00000167553	tubulin alpha 1c
		UniProt	A0A1W2PQM2 F5H5D3 F8VRK1 F8VS66 H0YHV2 Q9BQE3
		NCBI	84790
		KEGG signaling	Tight junction Apoptosis Gap junction
		KEGG metabolic	Phagosome
15	LCOR	ENSG00000196233	ligand dependent nuclear receptor corepressor
		UniProt	A0A1P0AZG4 Q96JN0
		NCBI	84458
20	EZH2	ENSG00000106462	enhancer of zeste 2 polycomb repressive complex 2 subunit
		UniProt	E9PDH6 G3XAL2 Q15910
		NCBI	2146
		KEGG metabolic	Lysine degradation
19	EZH1	ENSG00000108799	enhancer of zeste 1 polycomb repressive complex 2 subunit
		UniProt	A0A0A0MSY9 K7EIH5 K7EJU6 K7EK26 K7EK66 K7EM79 K7ENP2 K7EPC0 K7ESB9 Q92800
		NCBI	2145
		KEGG metabolic	Lysine degradation
15	POLR2H	ENSG00000163882	RNA polymerase II subunit H
		UniProt	C9JJJ9 C9JLU1 P52434
		NCBI	5437
		KEGG signaling	Cytosolic DNA-sensing pathway
		KEGG metabolic	RNA polymerase
22	RBBP7	ENSG00000102054	RB binding protein 7, chromatin remodeling factor
		UniProt	C9J7L0 C9JAJ9 E9PC52 Q16576 Q5JNZ6 Q5JP01 Q5JP02
		NCBI	5931
14	EPOP	ENSG00000273604	elongin BC and polycomb repressive complex 2 associated protein
		UniProt	A6NHQ4
		NCBI	100170841
23	SUZ12	ENSG00000178691	SUZ12 polycomb repressive complex 2 subunit
		UniProt	J3QQW9 Q15022
		NCBI	23512
11	SETX	ENSG00000107290	senataxin
		UniProt	Q7Z333 X6RI79
		NCBI	23064
22	RBBP4	ENSG00000162521	RB binding protein 4, chromatin remodeling factor
		UniProt	C9JPP3 E9PIC4 E9PND5 E9PNS2 E9PNS6 H0YCT5 H0YDK2 H0YEU5 H0YF10 Q09028
		NCBI	5928
15	BLVRA	ENSG00000106605	biliverdin reductase A
		UniProt	C9J1E1 P53004
		NCBI	644
		KEGG metabolic	Porphyrin and chlorophyll metabolism
13	MYBBP1A	ENSG00000132382	MYB binding protein 1a
		UniProt	I3L1L3 I3L2H8 I3L311 Q9BQG0
		NCBI	10514
12	BRD2	ENSG00000204256	bromodomain containing 2
		UniProt	E9PIQ3 E9PKQ9 H0Y6K2 H0Y799 H0YDJ7 J3QR72 P25440 U3KPW0 U3KQA6
		NCBI	6046
3	APP	ENSG00000142192	amyloid beta precursor protein
		UniProt	A0A0A0MRG2 E9PG40 H7C0V9 H7C2L2 P05067
		NCBI	351
		KEGG signaling	Serotonergic synapse
12	PSMC1	ENSG00000100764	proteasome 26S subunit, ATPase 1
		UniProt	G3V4X1 P62191
		NCBI	5700
		KEGG metabolic	Proteasome
16	PHF1	ENSG00000112511	PHD finger protein 1
		UniProt	A0A087WVG4 A2AB22 A2AB23 A2AB25 E9PQT8 E9PQZ5 O43189
		NCBI	5252
2	THAP1	ENSG00000131931	THAP domain containing 1
		UniProt	E9PIS9 Q9NVV9
		NCBI	55145
3	BTRC	ENSG00000166167	beta-transducin repeat containing E3 ubiquitin protein ligase
		UniProt	B7Z3H4 Q5T1W7 Q9Y297
		NCBI	8945
		KEGG signaling	Oocyte meiosis Wnt signaling pathway Hedgehog signaling pathway Hippo signaling pathway
		KEGG metabolic	Ubiquitin mediated proteolysis
3	FBXW11	ENSG00000072803	F-box and WD repeat domain containing 11
		UniProt	E5RG78 E5RGC1 E5RH92 Q9UKB1
		NCBI	23291
		KEGG signaling	Oocyte meiosis Wnt signaling pathway Hedgehog signaling pathway Hippo signaling pathway
		KEGG metabolic	Ubiquitin mediated proteolysis
7	BCLAF1	ENSG00000029363	BCL2 associated transcription factor 1
		UniProt	A0A1W2PQ43 E9PJA7 E9PK09 E9PK91 E9PKI6 E9PQN2 H0YF00 H0YF14 H0YF63 Q9NYF8
		NCBI	9774
6	H1-1	ENSG00000124610	H1.1 linker histone, cluster member
		UniProt	Q02539
		NCBI	3024
6	IVNS1ABP	ENSG00000116679	influenza virus NS1A binding protein
		UniProt	H0Y5Y2 Q9Y6Y0 X6R674
		NCBI	10625
9	ICE1	ENSG00000164151	interactor of little elongation complex ELL subunit 1
		UniProt	A0A096LPH9 Q9Y2F5
		NCBI	23379
1	ATXN3	ENSG00000066427	ataxin 3
		UniProt	A0A087WXY4 A0A087X1A8 A0A0A0MS38 A0A2R8Y3X7 A0A2R8Y888 C9JQV6 D3VVH9 D3VVP3 D6R9I5 E9PJN5 F5H211 G3V2G1 G3V2G2 G3V328 G3V390 G3V3A6 G3V3R7 G3V3S5 G3V3T0 G3V3T6 G3V4B1 G3V4F4 G3V4F5 G3V4U9 G3V526 G3V5H3 P54252 S4R399
		NCBI	4287
		KEGG metabolic	Protein processing in endoplasmic reticulum
1	HMBOX1	ENSG00000147421	homeobox containing 1
		UniProt	E5RGZ2 E5RHH9 H0YBM8 H0YKJ1 H0YLF2 Q6NT76
		NCBI	79618

Enrichment analysis

Search for enrichment of pathways or functional gene sets for your subnetwork genes

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	jSquid_subnetworks.xml	277.82 KB
	H.sapiens_subnetwork.tsv	32.90 KB

Species:

Network information:

Filter Results:

Network appearance:

ENSG00000139154

EED

JARID2

MTF2

PHF19

CCT5

TUBA1C

LCOR

EZH2

EZH1

POLR2H

RBBP7

EPOP

SUZ12

SETX

RBBP4

BLVRA

MYBBP1A

BRD2

APP

PSMC1

PHF1

THAP1

BTRC

FBXW11

BCLAF1

H1-1

IVNS1ABP

ICE1

ATXN3

HMBOX1

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