Found 1 of 1 query genes

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Query interactions

Interaction partners
Confidence
Network
MEX
PIN
SCL
PHP
MIR
TFB
PEX
GIN
DOM
QMS
GRG
Evidence types
HSA
MMU
RNO
CFA
GGA
DRE
CIN
DME
CEL
BTA
SCE
ATH
SPO
BSU
ECO
PFA
DDI
SSO
SSC
MJA
OSA
Species
In Gold st.

ID Query gene
ID Query ortholog

Log-likelihood ratio (LLR)
	Highly positive
	Positive
	Zero
	Negative
	Highly negative
Known coupling
	This network
	Other network

2. ENSG00000131174
3. cytochrome c oxidase su…
- 2. COX7A2
  3. cytochrome c oxidase su…
  4. 1.000
  5. Complex
- 2. NDUFA4
  3. NDUFA4 mitochondrial co…
  4. 1.000
  5. Complex
- 2. COX6C
  3. cytochrome c oxidase su…
  4. 1.000
  5. Complex
- 2. COX6B1
  3. cytochrome c oxidase su…
  4. 1.000
  5. Complex
- 2. COX5A
  3. cytochrome c oxidase su…
  4. 1.000
  5. Complex
- 2. COX4I1
  3. cytochrome c oxidase su…
  4. 1.000
  5. Complex
- 2. SCO1
  3. synthesis of cytochrome…
  4. 0.991
  5. Complex
- 2. NDUFA2
  3. NADH:ubiquinone oxidore…
  4. 0.991
  5. Metabolic
- 2. NDUFA12
  3. NADH:ubiquinone oxidore…
  4. 0.985
  5. Metabolic
- 2. NDUFC1
  3. NADH:ubiquinone oxidore…
  4. 0.984
  5. PPI
- 2. COX6A1
  3. cytochrome c oxidase su…
  4. 0.983
  5. Metabolic
- 2. NDUFV2
  3. NADH:ubiquinone oxidore…
  4. 0.981
  5. Complex
- 2. NDUFS6
  3. NADH:ubiquinone oxidore…
  4. 0.981
  5. Metabolic
- 2. SDHB
  3. succinate dehydrogenase…
  4. 0.981
  5. Metabolic
- 2. UQCRB
  3. ubiquinol-cytochrome c …
  4. 0.979
  5. Metabolic
- 2. UQCRQ
  3. ubiquinol-cytochrome c …
  4. 0.978
  5. Metabolic
- 2. NDUFA8
  3. NADH:ubiquinone oxidore…
  4. 0.975
  5. Metabolic
- 2. NDUFS8
  3. NADH:ubiquinone oxidore…
  4. 0.975
  5. Metabolic
- 2. UQCRH
  3. ubiquinol-cytochrome c …
  4. 0.974
  5. Metabolic
- 2. NDUFB5
  3. NADH:ubiquinone oxidore…
  4. 0.972
  5. Metabolic
- 2. NDUFA7
  3. NADH:ubiquinone oxidore…
  4. 0.970
  5. Metabolic
- 2. NDUFB2
  3. NADH:ubiquinone oxidore…
  4. 0.968
  5. PPI
- 2. NDUFA6
  3. NADH:ubiquinone oxidore…
  4. 0.968
  5. Metabolic
- 2. CYCS
  3. cytochrome c, somatic
  4. 0.962
  5. Metabolic
- 2. NDUFS5
  3. NADH:ubiquinone oxidore…
  4. 0.962
  5. Metabolic
- 2. SDHC
  3. succinate dehydrogenase…
  4. 0.957
  5. Metabolic
- 2. NDUFA1
  3. NADH:ubiquinone oxidore…
  4. 0.956
  5. Metabolic
- 2. ATP5MC1
  3. ATP synthase membrane s…
  4. 0.953
  5. Metabolic
- 2. NDUFA9
  3. NADH:ubiquinone oxidore…
  4. 0.950
  5. Metabolic
- 2. ATP5MC2
  3. ATP synthase membrane s…
  4. 0.949
  5. Metabolic

Subnetwork gene interactions

ENSG00000131174

cytochrome c oxidase subunit 7B

FunCoup

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Ensembl

ENSG00000131174

UniProt

NCBI

1349

SDHB

succinate dehydrogenase complex iron sulfur subunit B

FunCoup

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Ensembl

ENSG00000117118

UniProt

NCBI

6390

UQCRB

ubiquinol-cytochrome c reductase binding protein

FunCoup

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Ensembl

ENSG00000156467

UniProt

NCBI

7381

SDHC

succinate dehydrogenase complex subunit C

FunCoup

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Ensembl

ENSG00000143252

UniProt

NCBI

6391

NDUFA8

NADH:ubiquinone oxidoreductase subunit A8

FunCoup

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Ensembl

ENSG00000119421

UniProt

P51970

NCBI

4702

NDUFA7

NADH:ubiquinone oxidoreductase subunit A7

FunCoup

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Ensembl

ENSG00000267855

UniProt

NCBI

4701

NDUFS5

NADH:ubiquinone oxidoreductase subunit S5

FunCoup

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Ensembl

ENSG00000168653

UniProt

O43920

NCBI

4725

NDUFB5

NADH:ubiquinone oxidoreductase subunit B5

FunCoup

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Ensembl

ENSG00000136521

UniProt

NCBI

4711

COX6B1

cytochrome c oxidase subunit 6B1

FunCoup

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Ensembl

ENSG00000126267

UniProt

NCBI

1340

CYCS

cytochrome c, somatic

FunCoup

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Ensembl

ENSG00000172115

UniProt

NCBI

54205

COX5A

cytochrome c oxidase subunit 5A

FunCoup

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Ensembl

ENSG00000178741

UniProt

NCBI

9377

NDUFB2

NADH:ubiquinone oxidoreductase subunit B2

FunCoup

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Ensembl

ENSG00000090266

UniProt

NCBI

4708

NDUFA9

NADH:ubiquinone oxidoreductase subunit A9

FunCoup

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Ensembl

ENSG00000139180

UniProt

NCBI

4704

COX6A1

cytochrome c oxidase subunit 6A1

FunCoup

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Ensembl

ENSG00000111775

UniProt

P12074

NCBI

1337

NDUFA1

NADH:ubiquinone oxidoreductase subunit A1

FunCoup

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Ensembl

ENSG00000125356

UniProt

O15239

NCBI

4694

COX7A2

cytochrome c oxidase subunit 7A2

FunCoup

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Ensembl

ENSG00000112695

UniProt

NCBI

1347

COX4I1

cytochrome c oxidase subunit 4I1

FunCoup

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Ensembl

ENSG00000131143

UniProt

NCBI

1327

NDUFA6

NADH:ubiquinone oxidoreductase subunit A6

FunCoup

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Ensembl

ENSG00000184983

UniProt

NCBI

4700

NDUFS6

NADH:ubiquinone oxidoreductase subunit S6

FunCoup

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Ensembl

ENSG00000145494

UniProt

NCBI

4726

NDUFA2

NADH:ubiquinone oxidoreductase subunit A2

FunCoup

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Ensembl

ENSG00000131495

UniProt

O43678

NCBI

4695

NDUFC1

NADH:ubiquinone oxidoreductase subunit C1

FunCoup

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Ensembl

ENSG00000109390

UniProt

O43677

NCBI

4717

NDUFA4

NDUFA4 mitochondrial complex associated

FunCoup

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Ensembl

ENSG00000189043

UniProt

O00483

NCBI

4697

NDUFS8

NADH:ubiquinone oxidoreductase core subunit S8

FunCoup

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Ensembl

ENSG00000110717

UniProt

NCBI

4728

ATP5MC1

ATP synthase membrane subunit c locus 1

FunCoup

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Ensembl

ENSG00000159199

UniProt

NCBI

NDUFV2

NADH:ubiquinone oxidoreductase core subunit V2

FunCoup

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Ensembl

ENSG00000178127

UniProt

NCBI

4729

ATP5MC2

ATP synthase membrane subunit c locus 2

FunCoup

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Ensembl

ENSG00000135390

UniProt

NCBI

UQCRQ

ubiquinol-cytochrome c reductase complex III subunit VII

FunCoup

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Ensembl

ENSG00000164405

UniProt

O14949

NCBI

27089

NDUFA12

NADH:ubiquinone oxidoreductase subunit A12

FunCoup

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Ensembl

ENSG00000184752

UniProt

NCBI

55967

UQCRH

ubiquinol-cytochrome c reductase hinge protein

FunCoup

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Ensembl

ENSG00000173660

UniProt

NCBI

7388

SCO1

synthesis of cytochrome C oxidase 1

FunCoup

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Ensembl

ENSG00000133028

UniProt

NCBI

6341

COX6C

cytochrome c oxidase subunit 6C

FunCoup

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Ensembl

ENSG00000164919

UniProt

P09669

NCBI

1345

Query genes

		Identifier	Description
30	ENSG00000131174	ENSG00000131174	cytochrome c oxidase subunit 7B
		UniProt	A0A3B3IRN8 A0A3B3ISY5 A0A3B3ITX0 P24311
		NCBI	1349
		KEGG signaling	Cardiac muscle contraction
		KEGG metabolic	Oxidative phosphorylation

Subnetwork genes

		Identifier	Description
30	SDHB	ENSG00000117118	succinate dehydrogenase complex iron sulfur subunit B
		UniProt	A0A087WWT1 A0A087WXX8 P21912
		NCBI	6390
		KEGG metabolic	Oxidative phosphorylation Citrate cycle (TCA cycle) Carbon metabolism
30	UQCRB	ENSG00000156467	ubiquinol-cytochrome c reductase binding protein
		UniProt	B7Z2R2 E5RHG9 E5RIT7 P14927
		NCBI	7381
		KEGG signaling	Cardiac muscle contraction
		KEGG metabolic	Oxidative phosphorylation
28	SDHC	ENSG00000143252	succinate dehydrogenase complex subunit C
		UniProt	A0A087WZU7 D6RBX6 Q99643
		NCBI	6391
		KEGG metabolic	Oxidative phosphorylation Citrate cycle (TCA cycle) Carbon metabolism
30	NDUFA8	ENSG00000119421	NADH:ubiquinone oxidoreductase subunit A8
		UniProt	P51970
		NCBI	4702
		KEGG signaling	Retrograde endocannabinoid signaling
		KEGG metabolic	Oxidative phosphorylation
30	NDUFA7	ENSG00000267855	NADH:ubiquinone oxidoreductase subunit A7
		UniProt	M0R0N0 M0R1K9 O95182
		NCBI	4701
		KEGG signaling	Retrograde endocannabinoid signaling
		KEGG metabolic	Oxidative phosphorylation
29	NDUFS5	ENSG00000168653	NADH:ubiquinone oxidoreductase subunit S5
		UniProt	O43920
		NCBI	4725
		KEGG signaling	Retrograde endocannabinoid signaling
		KEGG metabolic	Oxidative phosphorylation
30	NDUFB5	ENSG00000136521	NADH:ubiquinone oxidoreductase subunit B5
		UniProt	A0A087WYD0 E7EWP0 F8WDD2 F8WDZ2 H0Y886 H7C568 H7C5C1 O43674
		NCBI	4711
		KEGG signaling	Retrograde endocannabinoid signaling
		KEGG metabolic	Oxidative phosphorylation
30	COX6B1	ENSG00000126267	cytochrome c oxidase subunit 6B1
		UniProt	A0A494C160 K7EQD3 P14854
		NCBI	1340
		KEGG signaling	Cardiac muscle contraction
		KEGG metabolic	Oxidative phosphorylation
30	CYCS	ENSG00000172115	cytochrome c, somatic
		UniProt	C9JFR7 P99999
		NCBI	54205
		KEGG signaling	p53 signaling pathway Apoptosis
30	COX5A	ENSG00000178741	cytochrome c oxidase subunit 5A
		UniProt	H3BNX8 H3BRI0 H3BRM5 H3BV69 P20674
		NCBI	9377
		KEGG signaling	Cardiac muscle contraction
		KEGG metabolic	Oxidative phosphorylation
28	NDUFB2	ENSG00000090266	NADH:ubiquinone oxidoreductase subunit B2
		UniProt	C9IZW8 C9IZZ2 C9JRV4 C9JXM4 F8WCJ6 H7C5B8 O95178
		NCBI	4708
		KEGG signaling	Retrograde endocannabinoid signaling
		KEGG metabolic	Oxidative phosphorylation
30	NDUFA9	ENSG00000139180	NADH:ubiquinone oxidoreductase subunit A9
		UniProt	F5GY40 F5H0J3 Q16795
		NCBI	4704
		KEGG signaling	Retrograde endocannabinoid signaling
		KEGG metabolic	Oxidative phosphorylation
30	COX6A1	ENSG00000111775	cytochrome c oxidase subunit 6A1
		UniProt	P12074
		NCBI	1337
		KEGG signaling	Cardiac muscle contraction
		KEGG metabolic	Oxidative phosphorylation
28	NDUFA1	ENSG00000125356	NADH:ubiquinone oxidoreductase subunit A1
		UniProt	O15239
		NCBI	4694
		KEGG signaling	Retrograde endocannabinoid signaling
		KEGG metabolic	Oxidative phosphorylation
30	COX7A2	ENSG00000112695	cytochrome c oxidase subunit 7A2
		UniProt	D6R9C3 D6RA35 D6RGV5 D6RIE3 H0UI06 H0Y8S6 P14406
		NCBI	1347
		KEGG signaling	Cardiac muscle contraction
		KEGG metabolic	Oxidative phosphorylation
30	COX4I1	ENSG00000131143	cytochrome c oxidase subunit 4I1
		UniProt	H3BN72 H3BNI5 H3BNV9 H3BPG0 H3BPR4 P13073 Q86WV2
		NCBI	1327
		KEGG signaling	Cardiac muscle contraction
		KEGG metabolic	Oxidative phosphorylation
30	NDUFA6	ENSG00000184983	NADH:ubiquinone oxidoreductase subunit A6
		UniProt	A0A2Y9D025 P56556 R4GN43
		NCBI	4700
		KEGG signaling	Retrograde endocannabinoid signaling
		KEGG metabolic	Oxidative phosphorylation
30	NDUFS6	ENSG00000145494	NADH:ubiquinone oxidoreductase subunit S6
		UniProt	D6RBT3 O75380
		NCBI	4726
		KEGG signaling	Retrograde endocannabinoid signaling
		KEGG metabolic	Oxidative phosphorylation
29	NDUFA2	ENSG00000131495	NADH:ubiquinone oxidoreductase subunit A2
		UniProt	O43678
		NCBI	4695
		KEGG signaling	Retrograde endocannabinoid signaling
		KEGG metabolic	Oxidative phosphorylation
29	NDUFC1	ENSG00000109390	NADH:ubiquinone oxidoreductase subunit C1
		UniProt	O43677
		NCBI	4717
		KEGG signaling	Retrograde endocannabinoid signaling
		KEGG metabolic	Oxidative phosphorylation
30	NDUFA4	ENSG00000189043	NDUFA4 mitochondrial complex associated
		UniProt	O00483
		NCBI	4697
		KEGG signaling	Retrograde endocannabinoid signaling
		KEGG metabolic	Oxidative phosphorylation
30	NDUFS8	ENSG00000110717	NADH:ubiquinone oxidoreductase core subunit S8
		UniProt	E9PJY7 E9PKH6 E9PML5 E9PN51 E9PPW7 F8W9K7 H0YCB2 H0YDT4 O00217 Q08E91
		NCBI	4728
		KEGG signaling	Retrograde endocannabinoid signaling
		KEGG metabolic	Oxidative phosphorylation
30	ATP5MC1	ENSG00000159199	ATP synthase membrane subunit c locus 1
		UniProt	D6R9H7 E7EPU7 E7EQ97 I3L0Y5 P05496
		NCBI	516
		KEGG metabolic	Oxidative phosphorylation
30	NDUFV2	ENSG00000178127	NADH:ubiquinone oxidoreductase core subunit V2
		UniProt	E7EPT4 J3KRB4 J3QS34 P19404
		NCBI	4729
		KEGG signaling	Retrograde endocannabinoid signaling
		KEGG metabolic	Oxidative phosphorylation
30	ATP5MC2	ENSG00000135390	ATP synthase membrane subunit c locus 2
		UniProt	F8W041 Q06055
		NCBI	517
		KEGG metabolic	Oxidative phosphorylation
30	UQCRQ	ENSG00000164405	ubiquinol-cytochrome c reductase complex III subunit VII
		UniProt	O14949
		NCBI	27089
		KEGG signaling	Cardiac muscle contraction
		KEGG metabolic	Oxidative phosphorylation
30	NDUFA12	ENSG00000184752	NADH:ubiquinone oxidoreductase subunit A12
		UniProt	F8VRD8 F8VXI1 H0YID5 H0YIT1 Q9UI09
		NCBI	55967
		KEGG signaling	Retrograde endocannabinoid signaling
		KEGG metabolic	Oxidative phosphorylation
30	UQCRH	ENSG00000173660	ubiquinol-cytochrome c reductase hinge protein
		UniProt	A0A087WTF2 A0A087X2B9 P07919
		NCBI	7388
		KEGG signaling	Cardiac muscle contraction
		KEGG metabolic	Oxidative phosphorylation
25	SCO1	ENSG00000133028	synthesis of cytochrome C oxidase 1
		UniProt	J3QL56 J3QR42 O75880
		NCBI	6341
30	COX6C	ENSG00000164919	cytochrome c oxidase subunit 6C
		UniProt	P09669
		NCBI	1345
		KEGG signaling	Cardiac muscle contraction
		KEGG metabolic	Oxidative phosphorylation

Enrichment analysis

Search for enrichment of pathways or functional gene sets for your subnetwork genes

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	jSquid_subnetworks.xml	334.01 KB
	H.sapiens_subnetwork.tsv	78.05 KB

Species:

Network information:

Filter Results:

Network appearance:

ENSG00000131174

SDHB

UQCRB

SDHC

NDUFA8

NDUFA7

NDUFS5

NDUFB5

COX6B1

CYCS

COX5A

NDUFB2

NDUFA9

COX6A1

NDUFA1

COX7A2

COX4I1

NDUFA6

NDUFS6

NDUFA2

NDUFC1

NDUFA4

NDUFS8

ATP5MC1

NDUFV2

ATP5MC2

UQCRQ

NDUFA12

UQCRH

SCO1

COX6C

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