Found 1 of 1 query genes

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Query interactions

Interaction partners
Confidence
Network
MEX
PIN
SCL
PHP
MIR
TFB
PEX
GIN
DOM
QMS
GRG
Evidence types
HSA
MMU
RNO
CFA
GGA
DRE
CIN
DME
CEL
BTA
SCE
ATH
SPO
BSU
ECO
PFA
DDI
SSO
SSC
MJA
OSA
Species
In Gold st.

ID Query gene
ID Query ortholog

Log-likelihood ratio (LLR)
	Highly positive
	Positive
	Zero
	Negative
	Highly negative
Known coupling
	This network
	Other network

2. ENSG00000125798
3. forkhead box A2
- 2. EN2
  3. engrailed homeobox 2
  4. 0.992
  5. PPI
- 2. FOXA1
  3. forkhead box A1
  4. 0.959
  5. PPI
- 2. HOXB13
  3. homeobox B13
  4. 0.938
  5. PPI
- 2. TLE1
  3. TLE family member 1, tr…
  4. 0.927
  5. PPI
- 2. HIF1A
  3. hypoxia inducible facto…
  4. 0.909
  5. PPI
- 2. TBP
  3. TATA-box binding protein
  4. 0.831
  5. PPI
- 2. OTX2
  3. orthodenticle homeobox 2
  4. 0.814
  5. PPI
- 2. NCOA1
  3. nuclear receptor coacti…
  4. 0.796
  5. PPI
- 2. LHX1
  3. LIM homeobox 1
  4. 0.794
  5. PPI
- 2. ONECUT1
  3. one cut homeobox 1
  4. 0.672
  5. PPI
- 2. CDC5L
  3. cell division cycle 5 l…
  4. 0.585
  5. Signaling
- 2. GATA3
  3. GATA binding protein 3
  4. 0.546
  5. Metabolic
- 2. KAT5
  3. lysine acetyltransferas…
  4. 0.484
  5. PPI
- 2. POU3F3
  3. POU class 3 homeobox 3
  4. 0.474
  5. Metabolic
- 2. ARNT
  3. aryl hydrocarbon recept…
  4. 0.428
  5. PPI
- 2. SOX1
  3. SRY-box transcription f…
  4. 0.426
  5. Metabolic
- 2. NKX2-2
  3. NK2 homeobox 2
  4. 0.408
  5. Metabolic

Subnetwork gene interactions

ENSG00000125798

forkhead box A2

FunCoup

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Ensembl

ENSG00000125798

UniProt

Q9Y261

NCBI

3170

GATA3

GATA binding protein 3

FunCoup

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Ensembl

ENSG00000107485

UniProt

NCBI

2625

FOXA1

forkhead box A1

FunCoup

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Ensembl

ENSG00000129514

UniProt

NCBI

3169

ONECUT1

one cut homeobox 1

FunCoup

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Ensembl

ENSG00000169856

UniProt

NCBI

3175

TBP

TATA-box binding protein

FunCoup

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Ensembl

ENSG00000112592

UniProt

NCBI

6908

KAT5

lysine acetyltransferase 5

FunCoup

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Ensembl

ENSG00000172977

UniProt

NCBI

10524

CDC5L

cell division cycle 5 like

FunCoup

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Ensembl

ENSG00000096401

UniProt

Q99459

NCBI

LHX1

LIM homeobox 1

FunCoup

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Ensembl

ENSG00000273706

UniProt

NCBI

3975

OTX2

orthodenticle homeobox 2

FunCoup

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Ensembl

ENSG00000165588

UniProt

NCBI

5015

ARNT

aryl hydrocarbon receptor nuclear translocator

FunCoup

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Ensembl

ENSG00000143437

UniProt

NCBI

HIF1A

hypoxia inducible factor 1 subunit alpha

FunCoup

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Ensembl

ENSG00000100644

UniProt

NCBI

3091

EN2

engrailed homeobox 2

FunCoup

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Ensembl

ENSG00000164778

UniProt

P19622

NCBI

2020

HOXB13

homeobox B13

FunCoup

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Ensembl

ENSG00000159184

UniProt

Q92826

NCBI

10481

NCOA1

nuclear receptor coactivator 1

FunCoup

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Ensembl

ENSG00000084676

UniProt

NCBI

8648

TLE1

TLE family member 1, transcriptional corepressor

FunCoup

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Ensembl

ENSG00000196781

UniProt

NCBI

7088

SOX1

SRY-box transcription factor 1

FunCoup

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Ensembl

ENSG00000182968

UniProt

O00570

NCBI

6656

POU3F3

POU class 3 homeobox 3

FunCoup

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Ensembl

ENSG00000198914

UniProt

P20264

NCBI

5455

NKX2-2

NK2 homeobox 2

FunCoup

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Ensembl

ENSG00000125820

UniProt

O95096

NCBI

4821

Query genes

		Identifier	Description
17	ENSG00000125798	ENSG00000125798	forkhead box A2
		UniProt	Q9Y261
		NCBI	3170

Subnetwork genes

		Identifier	Description
4	GATA3	ENSG00000107485	GATA binding protein 3
		UniProt	A0A2R8Y2A9 A0A2R8Y4T2 P23771
		NCBI	2625
4	FOXA1	ENSG00000129514	forkhead box A1
		UniProt	G3V4B9 P55317
		NCBI	3169
2	ONECUT1	ENSG00000169856	one cut homeobox 1
		UniProt	H0YMS2 Q9UBC0 U3KQR8
		NCBI	3175
4	TBP	ENSG00000112592	TATA-box binding protein
		UniProt	A0A1B0GVC6 H0Y6D8 P20226 Q32MN6 Q7Z6S4 Q7Z6S5
		NCBI	6908
		KEGG metabolic	Basal transcription factors
3	KAT5	ENSG00000172977	lysine acetyltransferase 5
		UniProt	E9PJI1 E9PMG8 E9PRL6 E9PRM3 E9PRS1 H0YEG3 H0YEP0 Q92993
		NCBI	10524
3	CDC5L	ENSG00000096401	cell division cycle 5 like
		UniProt	Q99459
		NCBI	988
		KEGG metabolic	Spliceosome
2	LHX1	ENSG00000273706	LIM homeobox 1
		UniProt	A0A087WY40 P48742
		NCBI	3975
2	OTX2	ENSG00000165588	orthodenticle homeobox 2
		UniProt	A0A5F9ZHY1 F1T0C9 G3V3J3 G3V3P9 P32243
		NCBI	5015
2	ARNT	ENSG00000143437	aryl hydrocarbon receptor nuclear translocator
		UniProt	A6NGV6 D6RDB3 P27540
		NCBI	405
		KEGG signaling	HIF-1 signaling pathway
3	HIF1A	ENSG00000100644	hypoxia inducible factor 1 subunit alpha
		UniProt	A8MYV6 F8W9L0 Q16665
		NCBI	3091
		KEGG signaling	Thyroid hormone signaling pathway HIF-1 signaling pathway
		KEGG metabolic	Autophagy - animal
1	EN2	ENSG00000164778	engrailed homeobox 2
		UniProt	P19622
		NCBI	2020
1	HOXB13	ENSG00000159184	homeobox B13
		UniProt	Q92826
		NCBI	10481
1	NCOA1	ENSG00000084676	nuclear receptor coactivator 1
		UniProt	B5MCN7 Q15788
		NCBI	8648
		KEGG signaling	Thyroid hormone signaling pathway Estrogen signaling pathway
1	TLE1	ENSG00000196781	TLE family member 1, transcriptional corepressor
		UniProt	F6T2C8 Q04724 Q5T3G2 Q5T3G3
		NCBI	7088
2	SOX1	ENSG00000182968	SRY-box transcription factor 1
		UniProt	O00570
		NCBI	6656
1	POU3F3	ENSG00000198914	POU class 3 homeobox 3
		UniProt	P20264
		NCBI	5455
1	NKX2-2	ENSG00000125820	NK2 homeobox 2
		UniProt	O95096
		NCBI	4821

Enrichment analysis

Search for enrichment of pathways or functional gene sets for your subnetwork genes

To use PathwAX, first use the button below to copy the subnetwork genes and then paste them in PathwAX

Copied subnetwork genes to clipboard

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	jSquid_subnetworks.xml	121.71 KB
	H.sapiens_subnetwork.tsv	4.64 KB

Species:

Network information:

Filter Results:

Network appearance:

ENSG00000125798

GATA3

FOXA1

ONECUT1

TBP

KAT5

CDC5L

LHX1

OTX2

ARNT

HIF1A

EN2

HOXB13

NCOA1

TLE1

SOX1

POU3F3

NKX2-2

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