Found 1 of 1 query genes

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Query interactions

Interaction partners
Confidence
Network
MEX
PIN
SCL
PHP
MIR
TFB
PEX
GIN
DOM
QMS
GRG
Evidence types
HSA
MMU
RNO
CFA
GGA
DRE
CIN
DME
CEL
BTA
SCE
ATH
SPO
BSU
ECO
PFA
DDI
SSO
SSC
MJA
OSA
Species
In Gold st.

ID Query gene
ID Query ortholog

Log-likelihood ratio (LLR)
	Highly positive
	Positive
	Zero
	Negative
	Highly negative
Known coupling
	This network
	Other network

2. ENSG00000122550
3. kelch like family membe…
- 2. KLHL20
  3. kelch like family membe…
  4. 0.999
  5. PPI
- 2. KEAP1
  3. kelch like ECH associat…
  4. 0.999
  5. PPI
- 2. KLHL9
  3. kelch like family membe…
  4. 0.998
  5. PPI
- 2. KLHL15
  3. kelch like family membe…
  4. 0.997
  5. PPI
- 2. VDAC2
  3. voltage dependent anion…
  4. 0.997
  5. Complex
- 2. RBX1
  3. ring-box 1
  4. 0.997
  5. PPI
- 2. ARIH1
  3. ariadne RBR E3 ubiquiti…
  4. 0.996
  5. PPI
- 2. CKAP5
  3. cytoskeleton associated…
  4. 0.995
  5. PPI
- 2. CUL3
  3. cullin 3
  4. 0.995
  5. PPI
- 2. KLHL12
  3. kelch like family membe…
  4. 0.993
  5. PPI
- 2. SKP1
  3. S-phase kinase associat…
  4. 0.989
  5. PPI
- 2. KLHL41
  3. kelch like family membe…
  4. 0.988
  5. PPI
- 2. IVNS1ABP
  3. influenza virus NS1A bi…
  4. 0.983
  5. PPI
- 2. KLHL13
  3. kelch like family membe…
  4. 0.980
  5. PPI
- 2. KLHL22
  3. kelch like family membe…
  4. 0.977
  5. PPI
- 2. OTUD6B
  3. OTU deubiquitinase 6B
  4. 0.972
  5. Complex
- 2. KLHL2
  3. kelch like family membe…
  4. 0.960
  5. PPI
- 2. KBTBD2
  3. kelch repeat and BTB do…
  4. 0.951
  5. PPI
- 2. KLHL8
  3. kelch like family membe…
  4. 0.949
  5. PPI
- 2. ENC1
  3. ectodermal-neural corte…
  4. 0.948
  5. PPI
- 2. RACGAP1
  3. Rac GTPase activating p…
  4. 0.929
  5. Complex
- 2. MRPL50
  3. mitochondrial ribosomal…
  4. 0.928
  5. Complex
- 2. NUP153
  3. nucleoporin 153
  4. 0.923
  5. PPI
- 2. APOBEC3B
  3. apolipoprotein B mRNA e…
  4. 0.922
  5. Complex
- 2. KLHL26
  3. kelch like family membe…
  4. 0.895
  5. PPI
- 2. PRKCI
  3. protein kinase C iota
  4. 0.894
  5. Complex
- 2. CBX3
  3. chromobox 3
  4. 0.890
  5. Complex
- 2. BOD1L1
  3. biorientation of chromo…
  4. 0.884
  5. PPI
- 2. BBS9
  3. Bardet-Biedl syndrome 9
  4. 0.879
  5. Complex
- 2. MICAL3
  3. microtubule associated …
  4. 0.877
  5. Complex

Subnetwork gene interactions

ENSG00000122550

kelch like family member 7

FunCoup

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Ensembl

ENSG00000122550

UniProt

NCBI

55975

CBX3

chromobox 3

FunCoup

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Ensembl

ENSG00000122565

UniProt

NCBI

11335

MRPL50

mitochondrial ribosomal protein L50

FunCoup

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Ensembl

ENSG00000136897

UniProt

Q8N5N7

NCBI

54534

KBTBD2

kelch repeat and BTB domain containing 2

FunCoup

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Ensembl

ENSG00000170852

UniProt

NCBI

25948

KLHL12

kelch like family member 12

FunCoup

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Ensembl

ENSG00000117153

UniProt

NCBI

59349

RACGAP1

Rac GTPase activating protein 1

FunCoup

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Ensembl

ENSG00000161800

UniProt

NCBI

29127

SKP1

S-phase kinase associated protein 1

FunCoup

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Ensembl

ENSG00000113558

UniProt

NCBI

6500

CKAP5

cytoskeleton associated protein 5

FunCoup

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Ensembl

ENSG00000175216

UniProt

NCBI

9793

KEAP1

kelch like ECH associated protein 1

FunCoup

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Ensembl

ENSG00000079999

UniProt

NCBI

9817

KLHL13

kelch like family member 13

FunCoup

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Ensembl

ENSG00000003096

UniProt

NCBI

90293

KLHL15

kelch like family member 15

FunCoup

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Ensembl

ENSG00000174010

UniProt

Q96M94

NCBI

80311

ARIH1

ariadne RBR E3 ubiquitin protein ligase 1

FunCoup

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Ensembl

ENSG00000166233

UniProt

NCBI

25820

KLHL2

kelch like family member 2

FunCoup

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Ensembl

ENSG00000109466

UniProt

NCBI

11275

KLHL22

kelch like family member 22

FunCoup

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Ensembl

ENSG00000099910

UniProt

NCBI

84861

OTUD6B

OTU deubiquitinase 6B

FunCoup

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Ensembl

ENSG00000155100

UniProt

NCBI

51633

KLHL26

kelch like family member 26

FunCoup

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Ensembl

ENSG00000167487

UniProt

NCBI

55295

KLHL8

kelch like family member 8

FunCoup

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Ensembl

ENSG00000145332

UniProt

NCBI

57563

KLHL41

kelch like family member 41

FunCoup

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Ensembl

ENSG00000239474

UniProt

O60662

NCBI

10324

KLHL9

kelch like family member 9

FunCoup

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Ensembl

ENSG00000198642

UniProt

Q9P2J3

NCBI

55958

IVNS1ABP

influenza virus NS1A binding protein

FunCoup

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Ensembl

ENSG00000116679

UniProt

NCBI

10625

MICAL3

microtubule associated monooxygenase, calponin and LIM domain containing 3

FunCoup

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Ensembl

ENSG00000243156

UniProt

NCBI

57553

ENC1

ectodermal-neural cortex 1

FunCoup

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Ensembl

ENSG00000171617

UniProt

NCBI

8507

KLHL20

kelch like family member 20

FunCoup

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Ensembl

ENSG00000076321

UniProt

Q9Y2M5

NCBI

27252

CUL3

cullin 3

FunCoup

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Ensembl

ENSG00000036257

UniProt

NCBI

8452

VDAC2

voltage dependent anion channel 2

FunCoup

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Ensembl

ENSG00000165637

UniProt

NCBI

7417

RBX1

ring-box 1

FunCoup

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Ensembl

ENSG00000100387

UniProt

P62877

NCBI

9978

BOD1L1

biorientation of chromosomes in cell division 1 like 1

FunCoup

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Ensembl

ENSG00000038219

UniProt

NCBI

259282

APOBEC3B

apolipoprotein B mRNA editing enzyme catalytic subunit 3B

FunCoup

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Ensembl

ENSG00000179750

UniProt

NCBI

9582

BBS9

Bardet-Biedl syndrome 9

FunCoup

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Ensembl

ENSG00000122507

UniProt

NCBI

27241

PRKCI

protein kinase C iota

FunCoup

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Ensembl

ENSG00000163558

UniProt

P41743

NCBI

5584

NUP153

nucleoporin 153

FunCoup

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Ensembl

ENSG00000124789

UniProt

P49790

NCBI

9972

Query genes

		Identifier	Description
30	ENSG00000122550	ENSG00000122550	kelch like family member 7
		UniProt	E5RFN1 H7C259 Q8IXQ5
		NCBI	55975

Subnetwork genes

		Identifier	Description
8	CBX3	ENSG00000122565	chromobox 3
		UniProt	B8ZZ43 C9JMM0 Q13185 S4R2Y4
		NCBI	11335
3	MRPL50	ENSG00000136897	mitochondrial ribosomal protein L50
		UniProt	Q8N5N7
		NCBI	54534
15	KBTBD2	ENSG00000170852	kelch repeat and BTB domain containing 2
		UniProt	A0A087WXP9 C9JI11 C9JUE5 C9JZ29 Q8IY47
		NCBI	25948
17	KLHL12	ENSG00000117153	kelch like family member 12
		UniProt	J3QSX3 Q53G59 Q9H7R2
		NCBI	59349
6	RACGAP1	ENSG00000161800	Rac GTPase activating protein 1
		UniProt	F8VQF5 F8VQZ5 F8VRD2 F8VRL2 F8VS54 F8VUW9 F8VV37 F8VV39 F8VV47 F8VVE5 F8VVY0 F8VWX0 F8VWY4 F8VXH1 F8VYH6 F8VZ41 F8VZ66 F8W0L1 F8W1E5 F8W1T4 H0YIK5 Q9H0H5
		NCBI	29127
18	SKP1	ENSG00000113558	S-phase kinase associated protein 1
		UniProt	E5RGM3 E5RGM4 E5RHM3 E5RJR5 E5RK33 E7ERH2 F8W8N3 P63208
		NCBI	6500
		KEGG signaling	Oocyte meiosis Wnt signaling pathway Cell cycle TGF-beta signaling pathway
		KEGG metabolic	Ubiquitin mediated proteolysis Protein processing in endoplasmic reticulum
10	CKAP5	ENSG00000175216	cytoskeleton associated protein 5
		UniProt	E9PQH5 H0YCF6 H0YDX5 H0YEK7 Q14008
		NCBI	9793
19	KEAP1	ENSG00000079999	kelch like ECH associated protein 1
		UniProt	K7EJ49 K7EJD8 K7EMY1 K7EPZ3 K7EQX2 K7ESE0 Q14145
		NCBI	9817
		KEGG metabolic	Ubiquitin mediated proteolysis
16	KLHL13	ENSG00000003096	kelch like family member 13
		UniProt	A0A0C4DG80 C9JTS9 Q9P2N7
		NCBI	90293
		KEGG metabolic	Ubiquitin mediated proteolysis
16	KLHL15	ENSG00000174010	kelch like family member 15
		UniProt	Q96M94
		NCBI	80311
10	ARIH1	ENSG00000166233	ariadne RBR E3 ubiquitin protein ligase 1
		UniProt	A0A087WT96 H3BNB9 H3BSK4 H3BUS0 Q9Y4X5
		NCBI	25820
16	KLHL2	ENSG00000109466	kelch like family member 2
		UniProt	B4DFZ5 D6R9G5 D6RAP5 D6RGC3 E9PEX9 O95198
		NCBI	11275
19	KLHL22	ENSG00000099910	kelch like family member 22
		UniProt	C9J191 C9J2T1 C9J5F8 C9JHG1 C9JLE9 C9JRG9 Q53GT1
		NCBI	84861
4	OTUD6B	ENSG00000155100	OTU deubiquitinase 6B
		UniProt	A0A087X0W9 A0A0C4DH76 Q8N6M0
		NCBI	51633
11	KLHL26	ENSG00000167487	kelch like family member 26
		UniProt	M0QXE1 M0R049 M0R1N0 M0R1P3 Q53HC5
		NCBI	55295
14	KLHL8	ENSG00000145332	kelch like family member 8
		UniProt	D6RGH5 Q68DU9 Q9P2G9
		NCBI	57563
12	KLHL41	ENSG00000239474	kelch like family member 41
		UniProt	O60662
		NCBI	10324
18	KLHL9	ENSG00000198642	kelch like family member 9
		UniProt	Q9P2J3
		NCBI	55958
		KEGG metabolic	Ubiquitin mediated proteolysis
12	IVNS1ABP	ENSG00000116679	influenza virus NS1A binding protein
		UniProt	H0Y5Y2 Q9Y6Y0 X6R674
		NCBI	10625
4	MICAL3	ENSG00000243156	microtubule associated monooxygenase, calponin and LIM domain containing 3
		UniProt	A0A5F9ZHV5 C9J922 E9PP85 J3KRP8 J3KSK6 J3KTB6 J3QLA3 J3QQT0 J3QR21 Q7RTP6
		NCBI	57553
15	ENC1	ENSG00000171617	ectodermal-neural cortex 1
		UniProt	D6R9D7 O14682
		NCBI	8507
19	KLHL20	ENSG00000076321	kelch like family member 20
		UniProt	Q9Y2M5
		NCBI	27252
19	CUL3	ENSG00000036257	cullin 3
		UniProt	A0A087WTG3 A0A087X1R9 H7C1J0 H7C1L6 H7C399 Q13618
		NCBI	8452
		KEGG signaling	Hedgehog signaling pathway
		KEGG metabolic	Ubiquitin mediated proteolysis
9	VDAC2	ENSG00000165637	voltage dependent anion channel 2
		UniProt	A0A0A0MR02 A2A3S1 P45880 Q5JSD1 Q5JSD2
		NCBI	7417
		KEGG signaling	NOD-like receptor signaling pathway cGMP-PKG signaling pathway Calcium signaling pathway
13	RBX1	ENSG00000100387	ring-box 1
		UniProt	P62877
		NCBI	9978
		KEGG signaling	Oocyte meiosis Wnt signaling pathway HIF-1 signaling pathway Cell cycle TGF-beta signaling pathway
		KEGG metabolic	Ubiquitin mediated proteolysis Protein processing in endoplasmic reticulum Nucleotide excision repair
2	BOD1L1	ENSG00000038219	biorientation of chromosomes in cell division 1 like 1
		UniProt	F8WDD0 H0Y9Y2 Q8NFC6
		NCBI	259282
3	APOBEC3B	ENSG00000179750	apolipoprotein B mRNA editing enzyme catalytic subunit 3B
		UniProt	B0QYD3 Q9UH17
		NCBI	9582
3	BBS9	ENSG00000122507	Bardet-Biedl syndrome 9
		UniProt	A0A5F9ZGX9 A0A5F9ZGY2 A0A5F9ZH06 A0A5F9ZH14 A0A5F9ZH37 A0A5F9ZH74 A0A5F9ZHE7 A0A5F9ZHP5 C9JJ08 F8WCG5 H7BZ69 Q3SYG4
		NCBI	27241
2	PRKCI	ENSG00000163558	protein kinase C iota
		UniProt	P41743
		NCBI	5584
		KEGG signaling	Rap1 signaling pathway Tight junction Hippo signaling pathway Insulin signaling pathway
		KEGG metabolic	Endocytosis
3	NUP153	ENSG00000124789	nucleoporin 153
		UniProt	P49790
		NCBI	9972
		KEGG metabolic	RNA transport

Enrichment analysis

Search for enrichment of pathways or functional gene sets for your subnetwork genes

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	jSquid_subnetworks.xml	247.20 KB
	H.sapiens_subnetwork.tsv	28.60 KB

Species:

Network information:

Filter Results:

Network appearance:

ENSG00000122550

CBX3

MRPL50

KBTBD2

KLHL12

RACGAP1

SKP1

CKAP5

KEAP1

KLHL13

KLHL15

ARIH1

KLHL2

KLHL22

OTUD6B

KLHL26

KLHL8

KLHL41

KLHL9

IVNS1ABP

MICAL3

ENC1

KLHL20

CUL3

VDAC2

RBX1

BOD1L1

APOBEC3B

BBS9

PRKCI

NUP153

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