Found 1 of 1 query genes

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Query interactions

Interaction partners
Confidence
Network
MEX
PIN
SCL
PHP
MIR
TFB
PEX
GIN
DOM
QMS
GRG
Evidence types
HSA
MMU
RNO
CFA
GGA
DRE
CIN
DME
CEL
BTA
SCE
ATH
SPO
BSU
ECO
PFA
DDI
SSO
SSC
MJA
OSA
Species
In Gold st.

ID Query gene
ID Query ortholog

Log-likelihood ratio (LLR)
	Highly positive
	Positive
	Zero
	Negative
	Highly negative
Known coupling
	This network
	Other network

2. ENSG00000119953
3. survival motor neuron d…
- 2. PRPF3
  3. pre-mRNA processing fac…
  4. 1.000
  5. PPI
- 2. SF3A3
  3. splicing factor 3a subu…
  4. 1.000
  5. PPI
- 2. SF3B2
  3. splicing factor 3b subu…
  4. 1.000
  5. PPI
- 2. SF3B6
  3. splicing factor 3b subu…
  4. 1.000
  5. PPI
- 2. PPAN
  3. peter pan homolog
  4. 0.999
  5. PPI
- 2. SF3A2
  3. splicing factor 3a subu…
  4. 0.999
  5. PPI
- 2. GNL3
  3. G protein nucleolar 3
  4. 0.999
  5. PPI
- 2. EWSR1
  3. EWS RNA binding protein…
  4. 0.999
  5. PPI
- 2. SF3B3
  3. splicing factor 3b subu…
  4. 0.998
  5. PPI
- 2. RRP1B
  3. ribosomal RNA processin…
  4. 0.997
  5. PPI
- 2. SNRNP200
  3. small nuclear ribonucle…
  4. 0.996
  5. PPI
- 2. RUVBL1
  3. RuvB like AAA ATPase 1
  4. 0.996
  5. PPI
- 2. DDX21
  3. DExD-box helicase 21
  4. 0.996
  5. PPI
- 2. SNRPA1
  3. small nuclear ribonucle…
  4. 0.996
  5. PPI
- 2. TSR1
  3. TSR1 ribosome maturatio…
  4. 0.995
  5. PPI
- 2. DCPS
  3. decapping enzyme, scave…
  4. 0.995
  5. PPI
- 2. MAPKAPK2
  3. MAPK activated protein …
  4. 0.995
  5. PPI
- 2. U2AF1
  3. U2 small nuclear RNA au…
  4. 0.994
  5. Metabolic
- 2. TRRAP
  3. transformation/transcri…
  4. 0.993
  5. PPI
- 2. DDX50
  3. DExD-box helicase 50
  4. 0.991
  5. PPI
- 2. CDK5RAP3
  3. CDK5 regulatory subunit…
  4. 0.986
  5. PPI
- 2. LUC7L3
  3. LUC7 like 3 pre-mRNA sp…
  4. 0.986
  5. Metabolic
- 2. MAGOH
  3. mago homolog, exon junc…
  4. 0.984
  5. Metabolic
- 2. PPP1R8
  3. protein phosphatase 1 r…
  4. 0.983
  5. Metabolic
- 2. EIF3E
  3. eukaryotic translation …
  4. 0.982
  5. Metabolic
- 2. PRPF8
  3. pre-mRNA processing fac…
  4. 0.981
  5. Metabolic
- 2. SNW1
  3. SNW domain containing 1
  4. 0.980
  5. Metabolic
- 2. PRPF40A
  3. pre-mRNA processing fac…
  4. 0.980
  5. Complex
- 2. PNN
  3. pinin, desmosome associ…
  4. 0.979
  5. Metabolic
- 2. ALYREF
  3. Aly/REF export factor
  4. 0.975
  5. Metabolic

Subnetwork gene interactions

ENSG00000119953

survival motor neuron domain containing 1

FunCoup

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Ensembl

ENSG00000119953

UniProt

O75940

NCBI

10285

SNW1

SNW domain containing 1

FunCoup

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Ensembl

ENSG00000100603

UniProt

NCBI

22938

SF3A2

splicing factor 3a subunit 2

FunCoup

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Ensembl

ENSG00000104897

UniProt

NCBI

8175

U2AF1

U2 small nuclear RNA auxiliary factor 1

FunCoup

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Ensembl

ENSG00000160201

UniProt

NCBI

SF3B2

splicing factor 3b subunit 2

FunCoup

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Ensembl

ENSG00000087365

UniProt

NCBI

10992

EWSR1

EWS RNA binding protein 1

FunCoup

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Ensembl

ENSG00000182944

UniProt

NCBI

2130

DDX21

DExD-box helicase 21

FunCoup

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Ensembl

ENSG00000165732

UniProt

Q9NR30

NCBI

9188

LUC7L3

LUC7 like 3 pre-mRNA splicing factor

FunCoup

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Ensembl

ENSG00000108848

UniProt

NCBI

51747

SF3B3

splicing factor 3b subunit 3

FunCoup

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Ensembl

ENSG00000189091

UniProt

NCBI

23450

DCPS

decapping enzyme, scavenger

FunCoup

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Ensembl

ENSG00000110063

UniProt

NCBI

28960

SF3A3

splicing factor 3a subunit 3

FunCoup

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Ensembl

ENSG00000183431

UniProt

Q12874

NCBI

10946

PPP1R8

protein phosphatase 1 regulatory subunit 8

FunCoup

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Ensembl

ENSG00000117751

UniProt

NCBI

5511

EIF3E

eukaryotic translation initiation factor 3 subunit E

FunCoup

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Ensembl

ENSG00000104408

UniProt

NCBI

3646

RRP1B

ribosomal RNA processing 1B

FunCoup

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Ensembl

ENSG00000160208

UniProt

Q14684

NCBI

23076

SF3B6

splicing factor 3b subunit 6

FunCoup

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Ensembl

ENSG00000115128

UniProt

Q9Y3B4

NCBI

51639

RUVBL1

RuvB like AAA ATPase 1

FunCoup

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Ensembl

ENSG00000175792

UniProt

NCBI

8607

GNL3

G protein nucleolar 3

FunCoup

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Ensembl

ENSG00000163938

UniProt

NCBI

26354

PRPF40A

pre-mRNA processing factor 40 homolog A

FunCoup

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Ensembl

ENSG00000196504

UniProt

NCBI

55660

ALYREF

Aly/REF export factor

FunCoup

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Ensembl

ENSG00000183684

UniProt

NCBI

10189

SNRNP200

small nuclear ribonucleoprotein U5 subunit 200

FunCoup

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Ensembl

ENSG00000144028

UniProt

NCBI

23020

TSR1

TSR1 ribosome maturation factor

FunCoup

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Ensembl

ENSG00000167721

UniProt

NCBI

55720

PNN

pinin, desmosome associated protein

FunCoup

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Ensembl

ENSG00000100941

UniProt

NCBI

5411

PRPF8

pre-mRNA processing factor 8

FunCoup

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Ensembl

ENSG00000174231

UniProt

NCBI

10594

TRRAP

transformation/transcription domain associated protein

FunCoup

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Ensembl

ENSG00000196367

UniProt

NCBI

8295

PPAN

peter pan homolog

FunCoup

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Ensembl

ENSG00000130810

UniProt

NCBI

56342
692312

MAGOH

mago homolog, exon junction complex subunit

FunCoup

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Ensembl

ENSG00000162385

UniProt

P61326

NCBI

4116

MAPKAPK2

MAPK activated protein kinase 2

FunCoup

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Ensembl

ENSG00000162889

UniProt

P49137

NCBI

9261

PRPF3

pre-mRNA processing factor 3

FunCoup

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Ensembl

ENSG00000117360

UniProt

O43395

NCBI

9129

DDX50

DExD-box helicase 50

FunCoup

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Ensembl

ENSG00000107625

UniProt

NCBI

79009

SNRPA1

small nuclear ribonucleoprotein polypeptide A'

FunCoup

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Ensembl

ENSG00000131876

UniProt

NCBI

6627

CDK5RAP3

CDK5 regulatory subunit associated protein 3

FunCoup

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Ensembl

ENSG00000108465

UniProt

NCBI

80279

Query genes

		Identifier	Description
30	ENSG00000119953	ENSG00000119953	survival motor neuron domain containing 1
		UniProt	O75940
		NCBI	10285
		KEGG metabolic	Spliceosome

Subnetwork genes

		Identifier	Description
26	SNW1	ENSG00000100603	SNW domain containing 1
		UniProt	G3V3A4 G3V4E0 G3V4X8 G3V5R3 Q13573
		NCBI	22938
		KEGG signaling	Notch signaling pathway
		KEGG metabolic	Spliceosome
22	SF3A2	ENSG00000104897	splicing factor 3a subunit 2
		UniProt	K7EMT0 Q15428
		NCBI	8175
		KEGG metabolic	Spliceosome
28	U2AF1	ENSG00000160201	U2 small nuclear RNA auxiliary factor 1
		UniProt	A0A1B0GW87 Q01081
		NCBI	102724594 7307
		KEGG metabolic	Spliceosome
27	SF3B2	ENSG00000087365	splicing factor 3b subunit 2
		UniProt	E9PIL8 E9PJ04 E9PJT3 E9PPJ0 H0YCG1 H0YEX5 Q13435
		NCBI	10992
		KEGG metabolic	Spliceosome
19	EWSR1	ENSG00000182944	EWS RNA binding protein 1
		UniProt	A0A0D9SFL3 B0QYJ3 B0QYJ4 B0QYJ5 B0QYJ6 B0QYJ7 B0QYK0 C9JGE3 F8WC90 H7BY36 Q01844
		NCBI	2130
23	DDX21	ENSG00000165732	DExD-box helicase 21
		UniProt	Q9NR30
		NCBI	9188
25	LUC7L3	ENSG00000108848	LUC7 like 3 pre-mRNA splicing factor
		UniProt	C9JL41 D6RDI2 D6RHH0 E7EN55 H0YA81 H0YAR4 H0YAX1 H0YAY6 H0YBV7 H7C5U7 J3KPP4 O95232 U3KQT3
		NCBI	51747
23	SF3B3	ENSG00000189091	splicing factor 3b subunit 3
		UniProt	H3BMB0 I3L4G7 J3QKV4 J3QL37 J3QRB2 Q15393
		NCBI	23450
		KEGG metabolic	Spliceosome
16	DCPS	ENSG00000110063	decapping enzyme, scavenger
		UniProt	A0A3B3ITF0 Q96C86
		NCBI	28960
		KEGG metabolic	RNA degradation
28	SF3A3	ENSG00000183431	splicing factor 3a subunit 3
		UniProt	Q12874
		NCBI	10946
		KEGG metabolic	Spliceosome
21	PPP1R8	ENSG00000117751	protein phosphatase 1 regulatory subunit 8
		UniProt	A0A0A0MT09 Q12972
		NCBI	5511
28	EIF3E	ENSG00000104408	eukaryotic translation initiation factor 3 subunit E
		UniProt	E5RGA2 E5RHS5 E5RII3 E5RIP5 E5RIT4 E5RJ25 H0YAW4 H0YBP5 H0YBR5 P60228
		NCBI	3646
		KEGG metabolic	RNA transport
27	RRP1B	ENSG00000160208	ribosomal RNA processing 1B
		UniProt	Q14684
		NCBI	23076
23	SF3B6	ENSG00000115128	splicing factor 3b subunit 6
		UniProt	Q9Y3B4
		NCBI	51639
		KEGG metabolic	Spliceosome
28	RUVBL1	ENSG00000175792	RuvB like AAA ATPase 1
		UniProt	E7ETR0 H7C4G5 H7C4I3 J3QLR1 Q9Y265
		NCBI	8607
		KEGG signaling	Wnt signaling pathway
21	GNL3	ENSG00000163938	G protein nucleolar 3
		UniProt	B4DMU5 C9JYH9 C9JZT7 Q9BVP2
		NCBI	26354
		KEGG metabolic	Ribosome biogenesis in eukaryotes
25	PRPF40A	ENSG00000196504	pre-mRNA processing factor 40 homolog A
		UniProt	A0A3F2YNY6 F5H578 H0YG38 H7BXZ7 H7C2N3 O75400
		NCBI	55660
		KEGG metabolic	Spliceosome
29	ALYREF	ENSG00000183684	Aly/REF export factor
		UniProt	E9PB61 Q86V81
		NCBI	10189
		KEGG metabolic	Spliceosome RNA transport mRNA surveillance pathway
24	SNRNP200	ENSG00000144028	small nuclear ribonucleoprotein U5 subunit 200
		UniProt	A0A494C1A5 O75643
		NCBI	23020
		KEGG metabolic	Spliceosome
26	TSR1	ENSG00000167721	TSR1 ribosome maturation factor
		UniProt	I3L1Q5 I3L4E8 I3L4T0 Q2NL82
		NCBI	55720
29	PNN	ENSG00000100941	pinin, desmosome associated protein
		UniProt	G3V579 G3V5F0 Q9H307
		NCBI	5411
		KEGG metabolic	RNA transport mRNA surveillance pathway
28	PRPF8	ENSG00000174231	pre-mRNA processing factor 8
		UniProt	I3L0J9 I3L1T8 I3L3Z8 Q6P2Q9
		NCBI	10594
		KEGG metabolic	Spliceosome
14	TRRAP	ENSG00000196367	transformation/transcription domain associated protein
		UniProt	A0A2R8YFJ4 C9K0N1 F2Z2U4 H0Y4W2 Q9Y4A5
		NCBI	8295
25	PPAN	ENSG00000130810	peter pan homolog
		UniProt	A8MV53 C9J3W3 C9JHF7 H7C446 Q9NQ55
		NCBI	56342 692312
27	MAGOH	ENSG00000162385	mago homolog, exon junction complex subunit
		UniProt	P61326
		NCBI	4116
		KEGG metabolic	Spliceosome RNA transport mRNA surveillance pathway
6	MAPKAPK2	ENSG00000162889	MAPK activated protein kinase 2
		UniProt	P49137
		NCBI	9261
		KEGG signaling	Neurotrophin signaling pathway MAPK signaling pathway VEGF signaling pathway C-type lectin receptor signaling pathway
24	PRPF3	ENSG00000117360	pre-mRNA processing factor 3
		UniProt	O43395
		NCBI	9129
		KEGG metabolic	Spliceosome
15	DDX50	ENSG00000107625	DExD-box helicase 50
		UniProt	A0A087WVC1 Q9BQ39 S4R3G6 S4R3V4
		NCBI	79009
18	SNRPA1	ENSG00000131876	small nuclear ribonucleoprotein polypeptide A'
		UniProt	H0YKK0 H0YLR3 H0YMA0 P09661
		NCBI	6627
		KEGG metabolic	Spliceosome
7	CDK5RAP3	ENSG00000108465	CDK5 regulatory subunit associated protein 3
		UniProt	J3KRI2 J3KRK4 J3KS63 J3KSD0 J3KTA5 J3QL86 J3QL95 J3QQS7 J3QQY1 J3QRM1 J3QRX0 J3QS62 Q96JB5
		NCBI	80279

Enrichment analysis

Search for enrichment of pathways or functional gene sets for your subnetwork genes

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	jSquid_subnetworks.xml	335.56 KB
	H.sapiens_subnetwork.tsv	62.43 KB

Species:

Network information:

Filter Results:

Network appearance:

ENSG00000119953

SNW1

SF3A2

U2AF1

SF3B2

EWSR1

DDX21

LUC7L3

SF3B3

DCPS

SF3A3

PPP1R8

EIF3E

RRP1B

SF3B6

RUVBL1

GNL3

PRPF40A

ALYREF

SNRNP200

TSR1

PNN

PRPF8

TRRAP

PPAN

MAGOH

MAPKAPK2

PRPF3

DDX50

SNRPA1

CDK5RAP3

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