Found 1 of 1 query genes

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Query interactions

Interaction partners
Confidence
Network
MEX
PIN
SCL
PHP
MIR
TFB
PEX
GIN
DOM
QMS
GRG
Evidence types
HSA
MMU
RNO
CFA
GGA
DRE
CIN
DME
CEL
BTA
SCE
ATH
SPO
BSU
ECO
PFA
DDI
SSO
SSC
MJA
OSA
Species
In Gold st.

ID Query gene
ID Query ortholog

Log-likelihood ratio (LLR)
	Highly positive
	Positive
	Zero
	Negative
	Highly negative
Known coupling
	This network
	Other network

2. ENSG00000099817
3. RNA polymerase II subun…
- 2. POLR2J
  3. RNA polymerase II subun…
  4. 1.000
  5. PPI
- 2. POLR2H
  3. RNA polymerase II subun…
  4. 1.000
  5. PPI
- 2. POLR2F
  3. RNA polymerase II subun…
  4. 1.000
  5. PPI
- 2. POLR2C
  3. RNA polymerase II subun…
  4. 1.000
  5. PPI
- 2. POLR2L
  3. RNA polymerase II subun…
  4. 1.000
  5. PPI
- 2. POLR2K
  3. RNA polymerase II subun…
  4. 1.000
  5. PPI
- 2. POLR2G
  3. RNA polymerase II subun…
  4. 1.000
  5. PPI
- 2. POLR2D
  3. RNA polymerase II subun…
  4. 1.000
  5. PPI
- 2. POLR1A
  3. RNA polymerase I subuni…
  4. 1.000
  5. PPI
- 2. POLR2I
  3. RNA polymerase II subun…
  4. 1.000
  5. PPI
- 2. POLR1B
  3. RNA polymerase I subuni…
  4. 1.000
  5. PPI
- 2. POLR1C
  3. RNA polymerase I and II…
  4. 1.000
  5. Complex
- 2. POLR2B
  3. RNA polymerase II subun…
  4. 1.000
  5. PPI
- 2. POLR3H
  3. RNA polymerase III subu…
  4. 1.000
  5. PPI
- 2. POLR2A
  3. RNA polymerase II subun…
  4. 1.000
  5. Complex
- 2. RUVBL2
  3. RuvB like AAA ATPase 2
  4. 1.000
  5. PPI
- 2. POLR3K
  3. RNA polymerase III subu…
  4. 1.000
  5. PPI
- 2. POLR1E
  3. RNA polymerase I subuni…
  4. 1.000
  5. Complex
- 2. RUVBL1
  3. RuvB like AAA ATPase 1
  4. 1.000
  5. PPI
- 2. POLR2J2
  3. RNA polymerase II subun…
  4. 1.000
  5. PPI
- 2. GTF2B
  3. general transcription f…
  4. 1.000
  5. PPI
- 2. POLR3B
  3. RNA polymerase III subu…
  4. 1.000
  5. PPI
- 2. POLR2J3
  3. RNA polymerase II subun…
  4. 1.000
  5. PPI
- 2. PCNA
  3. proliferating cell nucl…
  4. 1.000
  5. Complex
- 2. TCEA1
  3. transcription elongatio…
  4. 1.000
  5. PPI
- 2. POLR3F
  3. RNA polymerase III subu…
  4. 1.000
  5. PPI
- 2. POLR3C
  3. RNA polymerase III subu…
  4. 1.000
  5. PPI
- 2. ZNRD1
  3. zinc ribbon domain cont…
  4. 1.000
  5. PPI
- 2. POLR3A
  3. RNA polymerase III subu…
  4. 1.000
  5. PPI
- 2. POLR3D
  3. RNA polymerase III subu…
  4. 1.000
  5. PPI

Subnetwork gene interactions

ENSG00000099817

RNA polymerase II subunit E

FunCoup

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Ensembl

ENSG00000099817

UniProt

NCBI

5434

POLR2B

RNA polymerase II subunit B

FunCoup

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Ensembl

ENSG00000047315

UniProt

NCBI

5431

POLR1C

RNA polymerase I and III subunit C

FunCoup

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Ensembl

ENSG00000171453

UniProt

NCBI

9533

POLR3C

RNA polymerase III subunit C

FunCoup

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Ensembl

ENSG00000186141

UniProt

NCBI

10623

POLR3A

RNA polymerase III subunit A

FunCoup

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Ensembl

ENSG00000148606

UniProt

NCBI

11128

POLR2L

RNA polymerase II subunit L

FunCoup

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Ensembl

ENSG00000177700

UniProt

P62875

NCBI

5441

POLR2A

RNA polymerase II subunit A

FunCoup

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Ensembl

ENSG00000181222

UniProt

NCBI

5430

POLR2J2

RNA polymerase II subunit J2

FunCoup

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Ensembl

ENSG00000228049

UniProt

NCBI

POLR2H

RNA polymerase II subunit H

FunCoup

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Ensembl

ENSG00000163882

UniProt

NCBI

5437

POLR3D

RNA polymerase III subunit D

FunCoup

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Ensembl

ENSG00000168495

UniProt

NCBI

POLR1E

RNA polymerase I subunit E

FunCoup

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Ensembl

ENSG00000137054

UniProt

NCBI

64425

POLR2D

RNA polymerase II subunit D

FunCoup

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Ensembl

ENSG00000144231

UniProt

NCBI

5433

PCNA

proliferating cell nuclear antigen

FunCoup

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Ensembl

ENSG00000132646

UniProt

P12004

NCBI

5111

TCEA1

transcription elongation factor A1

FunCoup

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Ensembl

ENSG00000187735

UniProt

NCBI

6917

POLR2C

RNA polymerase II subunit C

FunCoup

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Ensembl

ENSG00000102978

UniProt

NCBI

5432

POLR2K

RNA polymerase II subunit K

FunCoup

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Ensembl

ENSG00000147669

UniProt

NCBI

5440

RUVBL1

RuvB like AAA ATPase 1

FunCoup

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Ensembl

ENSG00000175792

UniProt

NCBI

8607

ZNRD1

zinc ribbon domain containing 1

FunCoup

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Ensembl

ENSG00000066379

UniProt

Q9P1U0

NCBI

30834

POLR2I

RNA polymerase II subunit I

FunCoup

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Ensembl

ENSG00000105258

UniProt

NCBI

5438

RUVBL2

RuvB like AAA ATPase 2

FunCoup

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Ensembl

ENSG00000183207

UniProt

NCBI

10856

POLR3K

RNA polymerase III subunit K

FunCoup

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Ensembl

ENSG00000161980

UniProt

Q9Y2Y1

NCBI

51728

POLR2F

RNA polymerase II subunit F

FunCoup

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Ensembl

ENSG00000100142

UniProt

NCBI

5435

POLR2J3

RNA polymerase II subunit J3

FunCoup

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Ensembl

ENSG00000168255

UniProt

NCBI

548644

POLR3F

RNA polymerase III subunit F

FunCoup

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Ensembl

ENSG00000132664

UniProt

Q9H1D9

NCBI

10621

POLR2G

RNA polymerase II subunit G

FunCoup

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Ensembl

ENSG00000168002

UniProt

NCBI

5436

GTF2B

general transcription factor IIB

FunCoup

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Ensembl

ENSG00000137947

UniProt

NCBI

2959

POLR1A

RNA polymerase I subunit A

FunCoup

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Ensembl

ENSG00000068654

UniProt

NCBI

25885

POLR3H

RNA polymerase III subunit H

FunCoup

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Ensembl

ENSG00000100413

UniProt

NCBI

171568

POLR2J

RNA polymerase II subunit J

FunCoup

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Ensembl

ENSG00000005075

UniProt

NCBI

5439

POLR3B

RNA polymerase III subunit B

FunCoup

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Ensembl

ENSG00000013503

UniProt

NCBI

55703

POLR1B

RNA polymerase I subunit B

FunCoup

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Ensembl

ENSG00000125630

UniProt

NCBI

84172

Query genes

		Identifier	Description
30	ENSG00000099817	ENSG00000099817	RNA polymerase II subunit E
		UniProt	A0A087WVN5 A0A087WVZ9 A0A087WWX0 A0A0A0MQR7 K7EJ87 K7EQN2 P19388
		NCBI	5434
		KEGG signaling	Cytosolic DNA-sensing pathway
		KEGG metabolic	RNA polymerase

Subnetwork genes

		Identifier	Description
30	POLR2B	ENSG00000047315	RNA polymerase II subunit B
		UniProt	A0A1W2PPT5 C9J2Y9 C9J4M6 C9JMN3 C9JZW8 P30876
		NCBI	5431
		KEGG metabolic	RNA polymerase
30	POLR1C	ENSG00000171453	RNA polymerase I and III subunit C
		UniProt	A0A2R8Y5D3 A0A2R8Y8D6 A0A2R8YEY5 A0A2R8YEZ4 D6RDJ3 E7EQB9 H0Y723 O15160
		NCBI	9533
		KEGG signaling	Cytosolic DNA-sensing pathway
		KEGG metabolic	RNA polymerase
30	POLR3C	ENSG00000186141	RNA polymerase III subunit C
		UniProt	E9PHH9 Q9BUI4
		NCBI	10623
		KEGG signaling	Cytosolic DNA-sensing pathway
		KEGG metabolic	RNA polymerase
30	POLR3A	ENSG00000148606	RNA polymerase III subunit A
		UniProt	O14802 Q7Z755 R4GMX2
		NCBI	11128
		KEGG signaling	Cytosolic DNA-sensing pathway
		KEGG metabolic	RNA polymerase
30	POLR2L	ENSG00000177700	RNA polymerase II subunit L
		UniProt	P62875
		NCBI	5441
		KEGG signaling	Cytosolic DNA-sensing pathway
		KEGG metabolic	RNA polymerase
30	POLR2A	ENSG00000181222	RNA polymerase II subunit A
		UniProt	A0A590UJN4 A0A590UKB6 P24928
		NCBI	5430
		KEGG metabolic	RNA polymerase
27	POLR2J2	ENSG00000228049	RNA polymerase II subunit J2
		UniProt	A6NFM0 Q9GZM3
		NCBI	246721 548644
		KEGG metabolic	RNA polymerase
30	POLR2H	ENSG00000163882	RNA polymerase II subunit H
		UniProt	C9JJJ9 C9JLU1 P52434
		NCBI	5437
		KEGG signaling	Cytosolic DNA-sensing pathway
		KEGG metabolic	RNA polymerase
28	POLR3D	ENSG00000168495	RNA polymerase III subunit D
		UniProt	E5RHT4 E7EQ68 P05423
		NCBI	661
		KEGG signaling	Cytosolic DNA-sensing pathway
		KEGG metabolic	RNA polymerase
29	POLR1E	ENSG00000137054	RNA polymerase I subunit E
		UniProt	E7EX70 Q9GZS1
		NCBI	64425
		KEGG metabolic	RNA polymerase
30	POLR2D	ENSG00000144231	RNA polymerase II subunit D
		UniProt	E9PB93 E9PHV4 O15514
		NCBI	5433
		KEGG metabolic	RNA polymerase
30	PCNA	ENSG00000132646	proliferating cell nuclear antigen
		UniProt	P12004
		NCBI	5111
		KEGG signaling	Tight junction Cell cycle
		KEGG metabolic	DNA replication Mismatch repair Nucleotide excision repair Base excision repair
30	TCEA1	ENSG00000187735	transcription elongation factor A1
		UniProt	A0A1W2PPV7 A0A1W2PPZ5 A0A1W2PRL9 A0A1W2PS15 B7Z4S1 E5RFI1 E5RIS7 E5RJ93 E5RK46 P23193
		NCBI	6917
30	POLR2C	ENSG00000102978	RNA polymerase II subunit C
		UniProt	H3BRR2 P19387
		NCBI	5432
		KEGG metabolic	RNA polymerase
30	POLR2K	ENSG00000147669	RNA polymerase II subunit K
		UniProt	E5RGX2 P53803
		NCBI	5440
		KEGG signaling	Cytosolic DNA-sensing pathway
		KEGG metabolic	RNA polymerase
30	RUVBL1	ENSG00000175792	RuvB like AAA ATPase 1
		UniProt	E7ETR0 H7C4G5 H7C4I3 J3QLR1 Q9Y265
		NCBI	8607
		KEGG signaling	Wnt signaling pathway
30	ZNRD1	ENSG00000066379	zinc ribbon domain containing 1
		UniProt	Q9P1U0
		NCBI	30834
		KEGG metabolic	RNA polymerase
30	POLR2I	ENSG00000105258	RNA polymerase II subunit I
		UniProt	K7EK49 K7EKS1 K7ENX4 P36954
		NCBI	5438
		KEGG metabolic	RNA polymerase
30	RUVBL2	ENSG00000183207	RuvB like AAA ATPase 2
		UniProt	A0A1W2PS22 A0A1W2PS48 M0QXI6 M0QXZ7 M0QYD8 M0R0Y3 M0R0Z0 Q9Y230 X6R2L4
		NCBI	10856
30	POLR3K	ENSG00000161980	RNA polymerase III subunit K
		UniProt	Q9Y2Y1
		NCBI	51728
		KEGG signaling	Cytosolic DNA-sensing pathway
		KEGG metabolic	RNA polymerase
30	POLR2F	ENSG00000100142	RNA polymerase II subunit F
		UniProt	B0QYL8 B0QYL9 F8WC47 H0Y2U7 H0Y439 P61218 U3KPV3 U3KPY1 U3KQB0 U3KQQ7 U3KQS8
		NCBI	5435
		KEGG signaling	Cytosolic DNA-sensing pathway
		KEGG metabolic	RNA polymerase
28	POLR2J3	ENSG00000168255	RNA polymerase II subunit J3
		UniProt	A0A0B4J1Z8 A0A0B4J2F8 E2QRJ6 E7EP90 E7EWC6 F8WF84 Q9H1A7
		NCBI	548644
		KEGG metabolic	RNA polymerase
30	POLR3F	ENSG00000132664	RNA polymerase III subunit F
		UniProt	Q9H1D9
		NCBI	10621
		KEGG signaling	Cytosolic DNA-sensing pathway
		KEGG metabolic	RNA polymerase
30	POLR2G	ENSG00000168002	RNA polymerase II subunit G
		UniProt	E9PIU7 E9PKH3 E9PS03 H0YEE4 P62487
		NCBI	5436
		KEGG metabolic	RNA polymerase
30	GTF2B	ENSG00000137947	general transcription factor IIB
		UniProt	B1APE1 B1APE2 Q00403
		NCBI	2959
		KEGG metabolic	Basal transcription factors
30	POLR1A	ENSG00000068654	RNA polymerase I subunit A
		UniProt	B9ZVN9 F2Z3I7 O95602
		NCBI	25885
		KEGG metabolic	RNA polymerase
30	POLR3H	ENSG00000100413	RNA polymerase III subunit H
		UniProt	E7ERZ2 F8WDS5 F8WDV1 Q9Y535
		NCBI	171568
		KEGG signaling	Cytosolic DNA-sensing pathway
		KEGG metabolic	RNA polymerase
30	POLR2J	ENSG00000005075	RNA polymerase II subunit J
		UniProt	F6S314 P52435
		NCBI	5439
		KEGG metabolic	RNA polymerase
28	POLR3B	ENSG00000013503	RNA polymerase III subunit B
		UniProt	F8VRU2 Q9NW08
		NCBI	55703
		KEGG signaling	Cytosolic DNA-sensing pathway
		KEGG metabolic	RNA polymerase
30	POLR1B	ENSG00000125630	RNA polymerase I subunit B
		UniProt	C9JJG2 C9JS83 F8WAK7 F8WBB9 F8WCS3 F8WDS4 H7C0D9 Q9H9Y6
		NCBI	84172
		KEGG metabolic	RNA polymerase

Enrichment analysis

Search for enrichment of pathways or functional gene sets for your subnetwork genes

To use PathwAX, first use the button below to copy the subnetwork genes and then paste them in PathwAX

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	jSquid_subnetworks.xml	342.40 KB
	H.sapiens_subnetwork.tsv	88.34 KB

Species:

Network information:

Filter Results:

Network appearance:

ENSG00000099817

POLR2B

POLR1C

POLR3C

POLR3A

POLR2L

POLR2A

POLR2J2

POLR2H

POLR3D

POLR1E

POLR2D

PCNA

TCEA1

POLR2C

POLR2K

RUVBL1

ZNRD1

POLR2I

RUVBL2

POLR3K

POLR2F

POLR2J3

POLR3F

POLR2G

GTF2B

POLR1A

POLR3H

POLR2J

POLR3B

POLR1B

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