Found 1 of 1 query genes

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Query interactions

Interaction partners
Confidence
Network
MEX
PIN
SCL
PHP
MIR
TFB
PEX
GIN
DOM
QMS
GRG
Evidence types
HSA
MMU
RNO
CFA
GGA
DRE
CIN
DME
CEL
BTA
SCE
ATH
SPO
BSU
ECO
PFA
DDI
SSO
SSC
MJA
OSA
Species
In Gold st.

ID Query gene
ID Query ortholog

Log-likelihood ratio (LLR)
	Highly positive
	Positive
	Zero
	Negative
	Highly negative
Known coupling
	This network
	Other network

2. ENSG00000095970
3. triggering receptor exp…
- 2. TYROBP
  3. transmembrane immune si…
  4. 1.000
  5. PPI
- 2. SEC13
  3. SEC13 homolog, nuclear …
  4. 1.000
  5. PPI
- 2. TBC1D14
  3. TBC1 domain family memb…
  4. 0.991
  5. PPI
- 2. EXOC6
  3. exocyst complex compone…
  4. 0.976
  5. PPI
- 2. NCSTN
  3. nicastrin
  4. 0.974
  5. PPI
- 2. DNPEP
  3. aspartyl aminopeptidase
  4. 0.924
  5. PPI
- 2. PARD3
  3. par-3 family cell polar…
  4. 0.861
  5. PPI
- 2. STX16
  3. syntaxin 16
  4. 0.731
  5. Metabolic
- 2. RAC2
  3. Rac family small GTPase…
  4. 0.724
  5. Metabolic
- 2. CAPG
  3. capping actin protein, …
  4. 0.716
  5. Metabolic
- 2. CCT3
  3. chaperonin containing T…
  4. 0.715
  5. Complex
- 2. DNM1L
  3. dynamin 1 like
  4. 0.711
  5. Metabolic
- 2. CCT5
  3. chaperonin containing T…
  4. 0.707
  5. Metabolic
- 2. UBB
  3. ubiquitin B
  4. 0.686
  5. Metabolic
- 2. NRP1
  3. neuropilin 1
  4. 0.668
  5. PPI
- 2. ARPC5
  3. actin related protein 2…
  4. 0.662
  5. Metabolic
- 2. PKM
  3. pyruvate kinase M1/2
  4. 0.641
  5. Metabolic
- 2. CSNK1D
  3. casein kinase 1 delta
  4. 0.640
  5. Metabolic
- 2. MAPK3
  3. mitogen-activated prote…
  4. 0.639
  5. Metabolic
- 2. PPP2R1A
  3. protein phosphatase 2 s…
  4. 0.599
  5. Metabolic
- 2. TUBGCP2
  3. tubulin gamma complex a…
  4. 0.598
  5. Metabolic
- 2. CORO1C
  3. coronin 1C
  4. 0.587
  5. Metabolic
- 2. GABRA3
  3. gamma-aminobutyric acid…
  4. 0.574
  5. Signaling
- 2. RPL3
  3. ribosomal protein L3
  4. 0.560
  5. Metabolic
- 2. PAK1
  3. p21 (RAC1) activated ki…
  4. 0.540
  5. Metabolic
- 2. YWHAE
  3. tyrosine 3-monooxygenas…
  4. 0.525
  5. Metabolic
- 2. RPL23
  3. ribosomal protein L23
  4. 0.515
  5. Metabolic
- 2. AP1G1
  3. adaptor related protein…
  4. 0.511
  5. Metabolic
- 2. ATP6V0A1
  3. ATPase H+ transporting …
  4. 0.500
  5. Complex
- 2. AP1S2
  3. adaptor related protein…
  4. 0.492
  5. Metabolic

Subnetwork gene interactions

ENSG00000095970

triggering receptor expressed on myeloid cells 2

FunCoup

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Ensembl

ENSG00000095970

UniProt

Q9NZC2

NCBI

54209

PPP2R1A

protein phosphatase 2 scaffold subunit Aalpha

FunCoup

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Ensembl

ENSG00000105568

UniProt

NCBI

5518

PKM

pyruvate kinase M1/2

FunCoup

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Ensembl

ENSG00000067225

UniProt

NCBI

5315

NCSTN

nicastrin

FunCoup

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Ensembl

ENSG00000162736

UniProt

NCBI

23385

YWHAE

tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein epsilon

FunCoup

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Ensembl

ENSG00000108953

UniProt

NCBI

7531

AP1G1

adaptor related protein complex 1 subunit gamma 1

FunCoup

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Ensembl

ENSG00000166747

UniProt

NCBI

RPL23

ribosomal protein L23

FunCoup

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Ensembl

ENSG00000125691

UniProt

NCBI

9349

TBC1D14

TBC1 domain family member 14

FunCoup

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Ensembl

ENSG00000132405

UniProt

NCBI

57533

UBB

ubiquitin B

FunCoup

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Ensembl

ENSG00000170315

UniProt

NCBI

7314

ATP6V0A1

ATPase H+ transporting V0 subunit a1

FunCoup

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Ensembl

ENSG00000033627

UniProt

NCBI

TYROBP

transmembrane immune signaling adaptor TYROBP

FunCoup

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Ensembl

ENSG00000011600

UniProt

NCBI

7305

GABRA3

gamma-aminobutyric acid type A receptor subunit alpha3

FunCoup

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Ensembl

ENSG00000011677

UniProt

P34903

NCBI

2556

DNM1L

dynamin 1 like

FunCoup

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Ensembl

ENSG00000087470

UniProt

NCBI

10059

RPL3

ribosomal protein L3

FunCoup

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Ensembl

ENSG00000100316

UniProt

NCBI

6122

SEC13

SEC13 homolog, nuclear pore and COPII coat complex component

FunCoup

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Ensembl

ENSG00000157020

UniProt

NCBI

6396

AP1S2

adaptor related protein complex 1 subunit sigma 2

FunCoup

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Ensembl

ENSG00000182287

UniProt

NCBI

8905

CCT5

chaperonin containing TCP1 subunit 5

FunCoup

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Ensembl

ENSG00000150753

UniProt

NCBI

22948

CORO1C

coronin 1C

FunCoup

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Ensembl

ENSG00000110880

UniProt

NCBI

23603

CAPG

capping actin protein, gelsolin like

FunCoup

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Ensembl

ENSG00000042493

UniProt

NCBI

NRP1

neuropilin 1

FunCoup

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Ensembl

ENSG00000099250

UniProt

NCBI

8829

TUBGCP2

tubulin gamma complex associated protein 2

FunCoup

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Ensembl

ENSG00000130640

UniProt

NCBI

10844

STX16

syntaxin 16

FunCoup

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Ensembl

ENSG00000124222

UniProt

NCBI

8675

ARPC5

actin related protein 2/3 complex subunit 5

FunCoup

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Ensembl

ENSG00000162704

UniProt

NCBI

10092

RAC2

Rac family small GTPase 2

FunCoup

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Ensembl

ENSG00000128340

UniProt

NCBI

5880

PAK1

p21 (RAC1) activated kinase 1

FunCoup

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Ensembl

ENSG00000149269

UniProt

NCBI

5058

MAPK3

mitogen-activated protein kinase 3

FunCoup

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Ensembl

ENSG00000102882

UniProt

NCBI

5595

CCT3

chaperonin containing TCP1 subunit 3

FunCoup

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Ensembl

ENSG00000163468

UniProt

NCBI

7203

CSNK1D

casein kinase 1 delta

FunCoup

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Ensembl

ENSG00000141551

UniProt

NCBI

1453

EXOC6

exocyst complex component 6

FunCoup

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Ensembl

ENSG00000138190

UniProt

NCBI

54536

DNPEP

aspartyl aminopeptidase

FunCoup

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Ensembl

ENSG00000123992

UniProt

NCBI

23549

PARD3

par-3 family cell polarity regulator

FunCoup

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Ensembl

ENSG00000148498

UniProt

NCBI

56288

Query genes

		Identifier	Description
30	ENSG00000095970	ENSG00000095970	triggering receptor expressed on myeloid cells 2
		UniProt	Q9NZC2
		NCBI	54209

Subnetwork genes

		Identifier	Description
22	PPP2R1A	ENSG00000105568	protein phosphatase 2 scaffold subunit Aalpha
		UniProt	B3KQV6 C9J9C1 E9PH38 M0QXG4 M0R0K6 P30153
		NCBI	5518
		KEGG signaling	Oocyte meiosis Long-term depression Tight junction TGF-beta signaling pathway AMPK signaling pathway Dopaminergic synapse PI3K-Akt signaling pathway Adrenergic signaling in cardiomyocytes Hippo signaling pathway Sphingolipid signaling pathway
		KEGG metabolic	mRNA surveillance pathway
20	PKM	ENSG00000067225	pyruvate kinase M1/2
		UniProt	B4DNK4 H3BN34 H3BQ34 H3BQZ3 H3BR70 H3BT25 H3BTJ2 H3BTN5 H3BU13 H3BUW1 P14618
		NCBI	5315
		KEGG signaling	Glucagon signaling pathway
		KEGG metabolic	Pyruvate metabolism Glycolysis / Gluconeogenesis Purine metabolism Biosynthesis of amino acids Carbon metabolism
8	NCSTN	ENSG00000162736	nicastrin
		UniProt	A0A2R8YCK1 A0A2R8YE20 A0A2U3TZL9 H0Y3Z4 H0Y6T7 Q5T205 Q5T209 Q5T210 Q5T211 Q92542
		NCBI	23385
		KEGG signaling	Notch signaling pathway
23	YWHAE	ENSG00000108953	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein epsilon
		UniProt	B4DJF2 I3L0W5 I3L3T1 K7EIT4 K7EM20 P62258
		NCBI	7531
		KEGG signaling	Neurotrophin signaling pathway NOD-like receptor signaling pathway Oocyte meiosis Cell cycle PI3K-Akt signaling pathway Hippo signaling pathway
18	AP1G1	ENSG00000166747	adaptor related protein complex 1 subunit gamma 1
		UniProt	B3KNW1 B4DGE1 H3BN71 H3BN75 H3BNN2 H3BNR4 H3BPN9 H3BR36 H3BRM7 H3BS13 H3BUN9 H3BV30 O43747
		NCBI	164
		KEGG metabolic	Lysosome
18	RPL23	ENSG00000125691	ribosomal protein L23
		UniProt	B9ZVP7 C9JD32 J3KT29 J3KTJ3 J3QQT9 P62829
		NCBI	9349
		KEGG metabolic	Ribosome
2	TBC1D14	ENSG00000132405	TBC1 domain family member 14
		UniProt	B9A071 C9J541 C9JP26 F5GXK4 H7BZD7 Q9P2M4
		NCBI	57533
14	UBB	ENSG00000170315	ubiquitin B
		UniProt	B4DV12 J3QKN0 J3QS39 J3QSA3 P0CG47
		NCBI	7314
		KEGG metabolic	Ubiquitin mediated proteolysis
16	ATP6V0A1	ENSG00000033627	ATPase H+ transporting V0 subunit a1
		UniProt	B7Z2A9 B7Z641 F5H1T6 K7ELZ6 K7EM24 K7EN36 K7ENA1 K7EPG4 K7EQW2 K7ERA0 K7ERA6 Q93050
		NCBI	535
		KEGG signaling	Synaptic vesicle cycle
		KEGG metabolic	Oxidative phosphorylation Phagosome Lysosome
2	TYROBP	ENSG00000011600	transmembrane immune signaling adaptor TYROBP
		UniProt	K7EKK0 K7ES93 O43914 X6RGC9
		NCBI	7305
		KEGG signaling	Natural killer cell mediated cytotoxicity
1	GABRA3	ENSG00000011677	gamma-aminobutyric acid type A receptor subunit alpha3
		UniProt	P34903
		NCBI	2556
		KEGG signaling	Taste transduction GABAergic synapse Retrograde endocannabinoid signaling Neuroactive ligand-receptor interaction
19	DNM1L	ENSG00000087470	dynamin 1 like
		UniProt	B4DDQ3 B4DPZ9 F8VR28 F8VUJ9 F8VYL3 F8VZ52 F8W1W3 H0YHY4 H0YI79 O00429
		NCBI	10059
		KEGG signaling	NOD-like receptor signaling pathway TNF signaling pathway
20	RPL3	ENSG00000100316	ribosomal protein L3
		UniProt	B5MCW2 F8WCR1 G5E9G0 H7C3M2 H7C422 P39023
		NCBI	6122
		KEGG metabolic	Ribosome
24	SEC13	ENSG00000157020	SEC13 homolog, nuclear pore and COPII coat complex component
		UniProt	A8MXL6 C9J0S2 C9JBJ5 C9JIB6 E7ERC8 P55735
		NCBI	6396
		KEGG signaling	mTOR signaling pathway
		KEGG metabolic	Protein processing in endoplasmic reticulum RNA transport
12	AP1S2	ENSG00000182287	adaptor related protein complex 1 subunit sigma 2
		UniProt	A0A5F9ZHW1 A0A5F9ZHX2 A0A5F9ZI43 A6NH01 F6SFB5 H0Y673 H7BZG6 P56377
		NCBI	8905
		KEGG metabolic	Lysosome
22	CCT5	ENSG00000150753	chaperonin containing TCP1 subunit 5
		UniProt	B7ZAR1 D6RIZ7 E7ENZ3 E9PCA1 H0Y914 H0Y958 P48643
		NCBI	22948
20	CORO1C	ENSG00000110880	coronin 1C
		UniProt	B4E3S0 F8VRE9 F8VSA4 F8VTT6 F8VUX3 F8VV53 F8VVB7 F8W1H8 H0YHL7 Q9ULV4
		NCBI	23603
11	CAPG	ENSG00000042493	capping actin protein, gelsolin like
		UniProt	B8ZZL6 E7ENU9 H7C0X8 P40121
		NCBI	822
1	NRP1	ENSG00000099250	neuropilin 1
		UniProt	E7EX60 E9PEP6 H0Y4A0 H0Y4N6 H0Y7Z2 O14786 Q5JWQ2 Q5JWQ4 Q5JWQ6 Q5T7F0 V9GYL7
		NCBI	8829
6	TUBGCP2	ENSG00000130640	tubulin gamma complex associated protein 2
		UniProt	B3KTU7 F2Z2B9 Q9BSJ2 R4GMM4
		NCBI	10844
11	STX16	ENSG00000124222	syntaxin 16
		UniProt	B7ZBM4 B7ZBM5 B7ZBM8 E9PLV7 E9PND6 F8W9Z6 H0YEW0 O14662 Q96NX8
		NCBI	8675
		KEGG signaling	SNARE interactions in vesicular transport
		KEGG metabolic	SNARE interactions in vesicular transport
19	ARPC5	ENSG00000162704	actin related protein 2/3 complex subunit 5
		UniProt	B1ALC0 O15511
		NCBI	10092
		KEGG signaling	Fc gamma R-mediated phagocytosis
		KEGG metabolic	Endocytosis
15	RAC2	ENSG00000128340	Rac family small GTPase 2
		UniProt	B1AH77 B1AH78 B1AH79 B1AH80 P15153
		NCBI	5880
		KEGG signaling	Leukocyte transendothelial migration MAPK signaling pathway VEGF signaling pathway Chemokine signaling pathway Sphingolipid signaling pathway Fc gamma R-mediated phagocytosis Fc epsilon RI signaling pathway Focal adhesion Rap1 signaling pathway Adherens junction Ras signaling pathway cAMP signaling pathway Wnt signaling pathway B cell receptor signaling pathway Natural killer cell mediated cytotoxicity
11	PAK1	ENSG00000149269	p21 (RAC1) activated kinase 1
		UniProt	B3KNX7 E9PJF8 E9PKH9 E9PM17 E9PMP2 E9PQW5 E9PRP6 H0YCG5 H0YCM0 H0YF55 Q13153
		NCBI	5058
		KEGG signaling	Fc gamma R-mediated phagocytosis Focal adhesion Ras signaling pathway cAMP signaling pathway Natural killer cell mediated cytotoxicity ErbB signaling pathway T cell receptor signaling pathway MAPK signaling pathway Hippo signaling pathway - multiple species Chemokine signaling pathway C-type lectin receptor signaling pathway
14	MAPK3	ENSG00000102882	mitogen-activated protein kinase 3
		UniProt	B3KR49 E9PBK7 E9PJF0 E9PQW4 E9PRH7 H0YDH9 H0YEX6 P27361
		NCBI	5595
		KEGG signaling	Adrenergic signaling in cardiomyocytes Chemokine signaling pathway Fc gamma R-mediated phagocytosis NOD-like receptor signaling pathway Fc epsilon RI signaling pathway Toll-like receptor signaling pathway FoxO signaling pathway B cell receptor signaling pathway cAMP signaling pathway Gap junction HIF-1 signaling pathway cGMP-PKG signaling pathway T cell receptor signaling pathway C-type lectin receptor signaling pathway TNF signaling pathway TGF-beta signaling pathway PI3K-Akt signaling pathway mTOR signaling pathway Vascular smooth muscle contraction Phospholipase D signaling pathway Sphingolipid signaling pathway Oocyte meiosis Focal adhesion Prolactin signaling pathway Melanogenesis Estrogen signaling pathway Progesterone-mediated oocyte maturation GnRH signaling pathway Insulin signaling pathway Thyroid hormone signaling pathway Neurotrophin signaling pathway Long-term potentiation Adherens junction Relaxin signaling pathway Serotonergic synapse Cholinergic synapse Glutamatergic synapse Oxytocin signaling pathway Retrograde endocannabinoid signaling MAPK signaling pathway Apelin signaling pathway VEGF signaling pathway Long-term depression Rap1 signaling pathway Ras signaling pathway Apoptosis Natural killer cell mediated cytotoxicity ErbB signaling pathway IL-17 signaling pathway
		KEGG metabolic	Autophagy - animal
19	CCT3	ENSG00000163468	chaperonin containing TCP1 subunit 3
		UniProt	B4DUR8 E9PM09 E9PQ35 E9PRC8 E9PRM9 E9PRN0 P49368 Q5SZW8 Q5SZX6 Q5SZX9
		NCBI	7203
13	CSNK1D	ENSG00000141551	casein kinase 1 delta
		UniProt	B4DLF1 H0Y2N6 H7BYT1 J3KRM8 J3KRS6 J3QQI9 J3QQU8 J3QS70 P48730
		NCBI	1453
		KEGG signaling	Gap junction Hedgehog signaling pathway Hippo signaling pathway
6	EXOC6	ENSG00000138190	exocyst complex component 6
		UniProt	B1AP46 E7EW84 F2Z3K0 H0Y5J8 Q8TAG9
		NCBI	54536
8	DNPEP	ENSG00000123992	aspartyl aminopeptidase
		UniProt	B9ZVU2 C9J1E2 C9JBE1 C9JRG3 E3W974 E3W979 E5RHR3 E5RIA4 E5RJ35 E7EMB6 E7EPX3 E7ETB3 F8WAN0 Q9ULA0
		NCBI	23549
3	PARD3	ENSG00000148498	par-3 family cell polarity regulator
		UniProt	B1AP52 F5GZI3 Q5VWU8 Q5VWV2 Q8TEW0
		NCBI	56288
		KEGG signaling	Rap1 signaling pathway Adherens junction Tight junction Chemokine signaling pathway Hippo signaling pathway Neuroactive ligand-receptor interaction
		KEGG metabolic	Endocytosis

Enrichment analysis

Search for enrichment of pathways or functional gene sets for your subnetwork genes

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	jSquid_subnetworks.xml	292.27 KB
	H.sapiens_subnetwork.tsv	40.78 KB

Species:

Network information:

Filter Results:

Network appearance:

ENSG00000095970

PPP2R1A

PKM

NCSTN

YWHAE

AP1G1

RPL23

TBC1D14

UBB

ATP6V0A1

TYROBP

GABRA3

DNM1L

RPL3

SEC13

AP1S2

CCT5

CORO1C

CAPG

NRP1

TUBGCP2

STX16

ARPC5

RAC2

PAK1

MAPK3

CCT3

CSNK1D

EXOC6

DNPEP

PARD3

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