Found 1 of 1 query genes

Network information:

Filter Results:

Evidence Source:
Filter by Tissue:

Select multiple tissues by holding down shift or ctrl.
Filter by Pathway:

Network appearance:

Label Type:
Node Size:
Charge:
Link distance:
Min confidence:

Query interactions

Interaction partners
Confidence
Network
MEX
PIN
SCL
PHP
MIR
TFB
PEX
GIN
DOM
QMS
GRG
Evidence types
HSA
MMU
RNO
CFA
GGA
DRE
CIN
DME
CEL
BTA
SCE
ATH
SPO
BSU
ECO
PFA
DDI
SSO
SSC
MJA
OSA
Species
In Gold st.

ID Query gene
ID Query ortholog

Log-likelihood ratio (LLR)
	Highly positive
	Positive
	Zero
	Negative
	Highly negative
Known coupling
	This network
	Other network

2. ENSG00000214706
3. interferon related deve…
- 2. FTSJ3
  3. FtsJ RNA 2'-O-methyltra…
  4. 0.998
  5. Complex
- 2. GTPBP4
  3. GTP binding protein 4
  4. 0.997
  5. Complex
- 2. EIF6
  3. eukaryotic translation …
  4. 0.996
  5. Complex
- 2. ZNF622
  3. zinc finger protein 622
  4. 0.995
  5. Complex
- 2. LYAR
  3. Ly1 antibody reactive
  4. 0.992
  5. Complex
- 2. GNL3
  3. G protein nucleolar 3
  4. 0.992
  5. Complex
- 2. EIF3J
  3. eukaryotic translation …
  4. 0.988
  5. PPI
- 2. USP36
  3. ubiquitin specific pept…
  4. 0.986
  5. PPI
- 2. PABPC4
  3. poly(A) binding protein…
  4. 0.985
  5. Complex
- 2. PSMD2
  3. proteasome 26S subunit,…
  4. 0.982
  5. PPI
- 2. TOP1
  3. DNA topoisomerase I
  4. 0.981
  5. Complex
- 2. PPM1G
  3. protein phosphatase, Mg…
  4. 0.979
  5. Complex
- 2. PTGES3L-AARSD1
  3. PTGES3L-AARSD1 readthro…
  4. 0.944
  5. PPI
- 2. AARSD1
  3. alanyl-tRNA synthetase …
  4. 0.942
  5. PPI
- 2. WDR46
  3. WD repeat domain 46
  4. 0.904
  5. Metabolic
- 2. GARS1
  3. glycyl-tRNA synthetase 1
  4. 0.866
  5. Metabolic
- 2. WDR3
  3. WD repeat domain 3
  4. 0.857
  5. Metabolic
- 2. PES1
  3. pescadillo ribosomal bi…
  4. 0.856
  5. Metabolic
- 2. UBE2O
  3. ubiquitin conjugating e…
  4. 0.831
  5. PPI
- 2. ABCF2 (2 of 2)
  3. ATP binding cassette su…
  4. 0.811
  5. Metabolic
- 2. PLAA
  3. phospholipase A2 activa…
  4. 0.810
  5. Metabolic
- 2. CWC15
  3. CWC15 spliceosome assoc…
  4. 0.808
  5. Metabolic
- 2. ABCF2 (1 of 2)
  3. ABCF2-H2BE1 readthrough
  4. 0.799
  5. Metabolic
- 2. RPF1
  3. ribosome production fac…
  4. 0.796
  5. Metabolic
- 2. GSPT1
  3. G1 to S phase transitio…
  4. 0.794
  5. Metabolic
- 2. HSP90AA1
  3. heat shock protein 90 a…
  4. 0.780
  5. Metabolic
- 2. PTGES3
  3. prostaglandin E synthas…
  4. 0.776
  5. Metabolic
- 2. CCDC124
  3. coiled-coil domain cont…
  4. 0.744
  5. Metabolic
- 2. NOC2L
  3. NOC2 like nucleolar ass…
  4. 0.739
  5. Metabolic
- 2. MPI
  3. mannose phosphate isome…
  4. 0.733
  5. Metabolic

Subnetwork gene interactions

ENSG00000214706

interferon related developmental regulator 2

FunCoup

Use as query
Use pair as query
Add to current query

Ensembl

ENSG00000214706

UniProt

NCBI

7866

EIF3J

eukaryotic translation initiation factor 3 subunit J

FunCoup

Use as query
Use pair as query
Add to current query

Ensembl

ENSG00000104131

UniProt

NCBI

8669

WDR3

WD repeat domain 3

FunCoup

Use as query
Use pair as query
Add to current query

Ensembl

ENSG00000065183

UniProt

NCBI

10885

GARS1

glycyl-tRNA synthetase 1

FunCoup

Use as query
Use pair as query
Add to current query

Ensembl

ENSG00000106105

UniProt

NCBI

2617

GSPT1

G1 to S phase transition 1

FunCoup

Use as query
Use pair as query
Add to current query

Ensembl

ENSG00000103342

UniProt

NCBI

2935

FTSJ3

FtsJ RNA 2'-O-methyltransferase 3

FunCoup

Use as query
Use pair as query
Add to current query

Ensembl

ENSG00000108592

UniProt

NCBI

117246

USP36

ubiquitin specific peptidase 36

FunCoup

Use as query
Use pair as query
Add to current query

Ensembl

ENSG00000055483

UniProt

NCBI

57602

GTPBP4

GTP binding protein 4

FunCoup

Use as query
Use pair as query
Add to current query

Ensembl

ENSG00000107937

UniProt

NCBI

23560

HSP90AA1

heat shock protein 90 alpha family class A member 1

FunCoup

Use as query
Use pair as query
Add to current query

Ensembl

ENSG00000080824

UniProt

NCBI

3320

TOP1

DNA topoisomerase I

FunCoup

Use as query
Use pair as query
Add to current query

Ensembl

ENSG00000198900

UniProt

P11387

NCBI

7150

LYAR

Ly1 antibody reactive

FunCoup

Use as query
Use pair as query
Add to current query

Ensembl

ENSG00000145220

UniProt

NCBI

55646

CCDC124

coiled-coil domain containing 124

FunCoup

Use as query
Use pair as query
Add to current query

Ensembl

ENSG00000007080

UniProt

NCBI

115098

GNL3

G protein nucleolar 3

FunCoup

Use as query
Use pair as query
Add to current query

Ensembl

ENSG00000163938

UniProt

NCBI

26354

WDR46

WD repeat domain 46

FunCoup

Use as query
Use pair as query
Add to current query

Ensembl

ENSG00000227057

UniProt

NCBI

9277

PABPC4

poly(A) binding protein cytoplasmic 4

FunCoup

Use as query
Use pair as query
Add to current query

Ensembl

ENSG00000090621

UniProt

NCBI

8761

NOC2L

NOC2 like nucleolar associated transcriptional repressor

FunCoup

Use as query
Use pair as query
Add to current query

Ensembl

ENSG00000188976

UniProt

Q9Y3T9

NCBI

26155

PES1

pescadillo ribosomal biogenesis factor 1

FunCoup

Use as query
Use pair as query
Add to current query

Ensembl

ENSG00000100029

UniProt

NCBI

23481

PLAA

phospholipase A2 activating protein

FunCoup

Use as query
Use pair as query
Add to current query

Ensembl

ENSG00000137055

UniProt

NCBI

9373

RPF1

ribosome production factor 1 homolog

FunCoup

Use as query
Use pair as query
Add to current query

Ensembl

ENSG00000117133

UniProt

NCBI

80135

PTGES3

prostaglandin E synthase 3

FunCoup

Use as query
Use pair as query
Add to current query

Ensembl

ENSG00000110958

UniProt

NCBI

10728

ZNF622

zinc finger protein 622

FunCoup

Use as query
Use pair as query
Add to current query

Ensembl

ENSG00000173545

UniProt

Q969S3

NCBI

90441

PPM1G

protein phosphatase, Mg2+/Mn2+ dependent 1G

FunCoup

Use as query
Use pair as query
Add to current query

Ensembl

ENSG00000115241

UniProt

O15355

NCBI

5496

ABCF2 (1 of 2)

ABCF2-H2BE1 readthrough

FunCoup

Use as query
Use pair as query
Add to current query

Ensembl

ENSG00000285292

UniProt

Q9UG63

NCBI

MPI

mannose phosphate isomerase

FunCoup

Use as query
Use pair as query
Add to current query

Ensembl

ENSG00000178802

UniProt

NCBI

4351

PSMD2

proteasome 26S subunit, non-ATPase 2

FunCoup

Use as query
Use pair as query
Add to current query

Ensembl

ENSG00000175166

UniProt

NCBI

5708

ABCF2 (2 of 2)

ATP binding cassette subfamily F member 2

FunCoup

Use as query
Use pair as query
Add to current query

Ensembl

ENSG00000033050

UniProt

NCBI

EIF6

eukaryotic translation initiation factor 6

FunCoup

Use as query
Use pair as query
Add to current query

Ensembl

ENSG00000242372

UniProt

NCBI

3692

UBE2O

ubiquitin conjugating enzyme E2 O

FunCoup

Use as query
Use pair as query
Add to current query

Ensembl

ENSG00000175931

UniProt

NCBI

63893

CWC15

CWC15 spliceosome associated protein homolog

FunCoup

Use as query
Use pair as query
Add to current query

Ensembl

ENSG00000150316

UniProt

Q9P013

NCBI

51503

AARSD1

alanyl-tRNA synthetase domain containing 1

FunCoup

Use as query
Use pair as query
Add to current query

Ensembl

ENSG00000266967

UniProt

NCBI

PTGES3L-AARSD1

PTGES3L-AARSD1 readthrough

FunCoup

Use as query
Use pair as query
Add to current query

Ensembl

ENSG00000108825

UniProt

NCBI

Query genes

		Identifier	Description
30	ENSG00000214706	ENSG00000214706	interferon related developmental regulator 2
		UniProt	A0A0R4J2F6 F8WEI6 H7C2Z4 H7C444 Q12894
		NCBI	7866

Subnetwork genes

		Identifier	Description
19	EIF3J	ENSG00000104131	eukaryotic translation initiation factor 3 subunit J
		UniProt	H0YGJ7 H0YLP3 O75822
		NCBI	8669
		KEGG metabolic	RNA transport
25	WDR3	ENSG00000065183	WD repeat domain 3
		UniProt	Q6PDA5 Q9UNX4
		NCBI	10885
		KEGG metabolic	Ribosome biogenesis in eukaryotes
27	GARS1	ENSG00000106105	glycyl-tRNA synthetase 1
		UniProt	F8WCK4 H7C443 P41250
		NCBI	2617
		KEGG metabolic	Aminoacyl-tRNA biosynthesis
20	GSPT1	ENSG00000103342	G1 to S phase transition 1
		UniProt	H3BMT9 H3BR35 H3BSV8 P15170
		NCBI	2935
		KEGG metabolic	mRNA surveillance pathway
26	FTSJ3	ENSG00000108592	FtsJ RNA 2'-O-methyltransferase 3
		UniProt	J3KRY4 J3KS36 J3KS74 J3QKT6 J3QR05 J3QRS5 J3QSE2 Q8IY81
		NCBI	117246
17	USP36	ENSG00000055483	ubiquitin specific peptidase 36
		UniProt	A0A075B784 E9PEW0 K7EIH0 K7EIT7 K7EJI3 K7EKL7 K7EKN3 K7ELR5 K7ELT3 K7EMM6 K7EPT1 K7EQS0 K7ERC1 K7ERP8 Q8IXW9 Q9P275 U3KQ92
		NCBI	57602
24	GTPBP4	ENSG00000107937	GTP binding protein 4
		UniProt	Q5T3R7 Q9BZE4
		NCBI	23560
		KEGG metabolic	Ribosome biogenesis in eukaryotes
25	HSP90AA1	ENSG00000080824	heat shock protein 90 alpha family class A member 1
		UniProt	A0A0U1RR69 G3V2J8 G3V592 H0YJF5 P07900
		NCBI	3320
		KEGG signaling	Antigen processing and presentation NOD-like receptor signaling pathway PI3K-Akt signaling pathway Estrogen signaling pathway Progesterone-mediated oocyte maturation IL-17 signaling pathway
		KEGG metabolic	Protein processing in endoplasmic reticulum
25	TOP1	ENSG00000198900	DNA topoisomerase I
		UniProt	P11387
		NCBI	7150
18	LYAR	ENSG00000145220	Ly1 antibody reactive
		UniProt	D6RDJ1 Q9NX58
		NCBI	55646
13	CCDC124	ENSG00000007080	coiled-coil domain containing 124
		UniProt	M0R2F5 Q96CT7
		NCBI	115098
23	GNL3	ENSG00000163938	G protein nucleolar 3
		UniProt	B4DMU5 C9JYH9 C9JZT7 Q9BVP2
		NCBI	26354
		KEGG metabolic	Ribosome biogenesis in eukaryotes
25	WDR46	ENSG00000227057	WD repeat domain 46
		UniProt	H0Y6G3 O15213
		NCBI	9277
22	PABPC4	ENSG00000090621	poly(A) binding protein cytoplasmic 4
		UniProt	B1ANR0 B1ANR1 H0Y5F5 H0Y6X6 H0YCC8 H0YEQ8 H0YER0 H0YEU6 Q13310
		NCBI	8761
		KEGG metabolic	RNA degradation RNA transport mRNA surveillance pathway
22	NOC2L	ENSG00000188976	NOC2 like nucleolar associated transcriptional repressor
		UniProt	Q9Y3T9
		NCBI	26155
26	PES1	ENSG00000100029	pescadillo ribosomal biogenesis factor 1
		UniProt	B3KXD6 B5MCF9 H7BYY8 H7C267 O00541
		NCBI	23481
14	PLAA	ENSG00000137055	phospholipase A2 activating protein
		UniProt	E5RIM3 H0YAU9 H0YBW4 H0YC16 Q9Y263
		NCBI	9373
		KEGG metabolic	Protein processing in endoplasmic reticulum
22	RPF1	ENSG00000117133	ribosome production factor 1 homolog
		UniProt	Q9H9Y2 X6R7Q1
		NCBI	80135
20	PTGES3	ENSG00000110958	prostaglandin E synthase 3
		UniProt	A0A087WYT3 B4DDC6 Q15185
		NCBI	10728
		KEGG metabolic	Arachidonic acid metabolism
20	ZNF622	ENSG00000173545	zinc finger protein 622
		UniProt	Q969S3
		NCBI	90441
19	PPM1G	ENSG00000115241	protein phosphatase, Mg2+/Mn2+ dependent 1G
		UniProt	O15355
		NCBI	5496
21	ABCF2 (1 of 2)	ENSG00000285292	ABCF2-H2BE1 readthrough
		UniProt	Q9UG63
		NCBI	10061 114483834
9	MPI	ENSG00000178802	mannose phosphate isomerase
		UniProt	B4DYB8 F5GX71 H3BM77 H3BMZ9 H3BN01 H3BNY8 H3BP57 H3BPB8 H3BPM5 H3BPP3 H3BPU7 H3BQX0 H3BT46 H3BT48 H3BU66 H3BUG1 H3BUZ9 P34949
		NCBI	4351
		KEGG metabolic	Fructose and mannose metabolism Amino sugar and nucleotide sugar metabolism
25	PSMD2	ENSG00000175166	proteasome 26S subunit, non-ATPase 2
		UniProt	C9JPC0 F8WBS8 H7C1H2 H7C2Q3 Q13200
		NCBI	5708
		KEGG metabolic	Proteasome
21	ABCF2 (2 of 2)	ENSG00000033050	ATP binding cassette subfamily F member 2
		UniProt	C9JHK9 C9JZV3 Q9UG63
		NCBI	10061 114483834
27	EIF6	ENSG00000242372	eukaryotic translation initiation factor 6
		UniProt	A0A0B4J1Y7 B7ZBH1 F8WD20 F8WDS6 P56537
		NCBI	3692
		KEGG metabolic	Ribosome biogenesis in eukaryotes
4	UBE2O	ENSG00000175931	ubiquitin conjugating enzyme E2 O
		UniProt	K7EQ12 K7ES11 Q9C0C9
		NCBI	63893
		KEGG metabolic	Ubiquitin mediated proteolysis
14	CWC15	ENSG00000150316	CWC15 spliceosome associated protein homolog
		UniProt	Q9P013
		NCBI	51503
		KEGG metabolic	Spliceosome
3	AARSD1	ENSG00000266967	alanyl-tRNA synthetase domain containing 1
		UniProt	H7C1K1 K7EQ85 K7N799 L7N2F4 L7N2F5 Q9BTE6
		NCBI	100885850 80755
2	PTGES3L-AARSD1	ENSG00000108825	PTGES3L-AARSD1 readthrough
		UniProt	C9J5N1 C9JUA3 H7C054 L7N2F6 Q9BTE6
		NCBI	100885850 80755

Enrichment analysis

Search for enrichment of pathways or functional gene sets for your subnetwork genes

To use PathwAX, first use the button below to copy the subnetwork genes and then paste them in PathwAX

Copied subnetwork genes to clipboard

Use as query
Add to current query

	jSquid_subnetworks.xml	300.27 KB
	H.sapiens_subnetwork.tsv	58.01 KB

Species:

Network information:

Filter Results:

Network appearance:

ENSG00000214706

EIF3J

WDR3

GARS1

GSPT1

FTSJ3

USP36

GTPBP4

HSP90AA1

TOP1

LYAR

CCDC124

GNL3

WDR46

PABPC4

NOC2L

PES1

PLAA

RPF1

PTGES3

ZNF622

PPM1G

ABCF2 (1 of 2)

MPI

PSMD2

ABCF2 (2 of 2)

EIF6

UBE2O

CWC15

AARSD1

PTGES3L-AARSD1

JavaScript is required.