Found 1 of 1 query genes

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Query interactions

Interaction partners
Confidence
Network
MEX
PIN
SCL
PHP
MIR
TFB
PEX
GIN
DOM
QMS
GRG
Evidence types
HSA
MMU
RNO
CFA
GGA
DRE
CIN
DME
CEL
BTA
SCE
ATH
SPO
BSU
ECO
PFA
DDI
SSO
SSC
MJA
OSA
Species
In Gold st.

ID Query gene
ID Query ortholog

Log-likelihood ratio (LLR)
	Highly positive
	Positive
	Zero
	Negative
	Highly negative
Known coupling
	This network
	Other network

2. ENSG00000197142
3. acyl-CoA synthetase lon…
- 2. SNRPE
  3. small nuclear ribonucle…
  4. 1.000
  5. PPI
- 2. C1QBP
  3. complement C1q binding …
  4. 0.999
  5. Complex
- 2. IDE
  3. insulin degrading enzyme
  4. 0.999
  5. Complex
- 2. GK
  3. glycerol kinase
  4. 0.998
  5. Metabolic
- 2. GPAM
  3. glycerol-3-phosphate ac…
  4. 0.997
  5. Complex
- 2. GK3P
  3. glycerol kinase 3 pseud…
  4. 0.997
  5. Metabolic
- 2. HSPA9
  3. heat shock protein fami…
  4. 0.996
  5. Metabolic
- 2. LPIN1
  3. lipin 1
  4. 0.996
  5. Metabolic
- 2. RPS27A
  3. ribosomal protein S27a
  4. 0.996
  5. Metabolic
- 2. AFG3L2
  3. AFG3 like matrix AAA pe…
  4. 0.996
  5. Metabolic
- 2. PMPCB
  3. peptidase, mitochondria…
  4. 0.995
  5. Metabolic
- 2. CAT
  3. catalase
  4. 0.993
  5. Metabolic
- 2. NME1
  3. NME/NM23 nucleoside dip…
  4. 0.993
  5. Complex
- 2. GPI
  3. glucose-6-phosphate iso…
  4. 0.993
  5. Metabolic
- 2. ATP5F1B
  3. ATP synthase F1 subunit…
  4. 0.992
  5. Metabolic
- 2. EIF5A
  3. eukaryotic translation …
  4. 0.991
  5. Metabolic
- 2. COPG1
  3. COPI coat complex subun…
  4. 0.991
  5. Metabolic
- 2. DNM1L
  3. dynamin 1 like
  4. 0.990
  5. Metabolic
- 2. HSP90B1
  3. heat shock protein 90 b…
  4. 0.990
  5. Metabolic
- 2. ATP5F1C
  3. ATP synthase F1 subunit…
  4. 0.990
  5. Metabolic
- 2. SDHB
  3. succinate dehydrogenase…
  4. 0.989
  5. Metabolic
- 2. ATP5F1A
  3. ATP synthase F1 subunit…
  4. 0.988
  5. Metabolic
- 2. CYB5A
  3. cytochrome b5 type A
  4. 0.988
  5. Metabolic
- 2. TKT
  3. transketolase
  4. 0.987
  5. Metabolic
- 2. CYB5R3
  3. cytochrome b5 reductase…
  4. 0.987
  5. Metabolic
- 2. UBA1
  3. ubiquitin like modifier…
  4. 0.986
  5. Metabolic
- 2. GK2
  3. glycerol kinase 2
  4. 0.986
  5. Metabolic
- 2. GRPEL1
  3. GrpE like 1, mitochondr…
  4. 0.985
  5. Metabolic
- 2. CREB3
  3. cAMP responsive element…
  4. 0.985
  5. PPI
- 2. ATP5PO
  3. ATP synthase peripheral…
  4. 0.985
  5. Metabolic

Subnetwork gene interactions

ENSG00000197142

acyl-CoA synthetase long chain family member 5

FunCoup

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Ensembl

ENSG00000197142

UniProt

Q9ULC5

NCBI

51703

TKT

transketolase

FunCoup

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Ensembl

ENSG00000163931

UniProt

NCBI

7086

GRPEL1

GrpE like 1, mitochondrial

FunCoup

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Ensembl

ENSG00000109519

UniProt

Q9HAV7

NCBI

80273

GK2

glycerol kinase 2

FunCoup

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Ensembl

ENSG00000196475

UniProt

Q14410

NCBI

2712

GK

glycerol kinase

FunCoup

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Ensembl

ENSG00000198814

UniProt

NCBI

2710

CYB5R3

cytochrome b5 reductase 3

FunCoup

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Ensembl

ENSG00000100243

UniProt

NCBI

1727

ATP5F1A

ATP synthase F1 subunit alpha

FunCoup

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Ensembl

ENSG00000152234

UniProt

NCBI

CYB5A

cytochrome b5 type A

FunCoup

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Ensembl

ENSG00000166347

UniProt

NCBI

1528

C1QBP

complement C1q binding protein

FunCoup

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Ensembl

ENSG00000108561

UniProt

NCBI

ATP5F1C

ATP synthase F1 subunit gamma

FunCoup

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Ensembl

ENSG00000165629

UniProt

P36542

NCBI

EIF5A

eukaryotic translation initiation factor 5A

FunCoup

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Ensembl

ENSG00000132507

UniProt

NCBI

1984

COPG1

COPI coat complex subunit gamma 1

FunCoup

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Ensembl

ENSG00000181789

UniProt

NCBI

22820

PMPCB

peptidase, mitochondrial processing subunit beta

FunCoup

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Ensembl

ENSG00000105819

UniProt

NCBI

9512

ATP5F1B

ATP synthase F1 subunit beta

FunCoup

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Ensembl

ENSG00000110955

UniProt

NCBI

HSP90B1

heat shock protein 90 beta family member 1

FunCoup

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Ensembl

ENSG00000166598

UniProt

NCBI

7184

NME1

NME/NM23 nucleoside diphosphate kinase 1

FunCoup

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Ensembl

ENSG00000239672

UniProt

NCBI

4830

HSPA9

heat shock protein family A (Hsp70) member 9

FunCoup

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Ensembl

ENSG00000113013

UniProt

NCBI

3313

ATP5PO

ATP synthase peripheral stalk subunit OSCP

FunCoup

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Ensembl

ENSG00000241837

UniProt

NCBI

UBA1

ubiquitin like modifier activating enzyme 1

FunCoup

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Ensembl

ENSG00000130985

UniProt

NCBI

7317

IDE

insulin degrading enzyme

FunCoup

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Ensembl

ENSG00000119912

UniProt

NCBI

3416

DNM1L

dynamin 1 like

FunCoup

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Ensembl

ENSG00000087470

UniProt

NCBI

10059

CAT

catalase

FunCoup

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Ensembl

ENSG00000121691

UniProt

NCBI

RPS27A

ribosomal protein S27a

FunCoup

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Ensembl

ENSG00000143947

UniProt

NCBI

6233

SNRPE

small nuclear ribonucleoprotein polypeptide E

FunCoup

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Ensembl

ENSG00000182004

UniProt

NCBI

6635

AFG3L2

AFG3 like matrix AAA peptidase subunit 2

FunCoup

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Ensembl

ENSG00000141385

UniProt

NCBI

10939

SDHB

succinate dehydrogenase complex iron sulfur subunit B

FunCoup

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Ensembl

ENSG00000117118

UniProt

NCBI

6390

CREB3

cAMP responsive element binding protein 3

FunCoup

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Ensembl

ENSG00000107175

UniProt

O43889

NCBI

10488

LPIN1

lipin 1

FunCoup

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Ensembl

ENSG00000134324

UniProt

NCBI

23175

GK3P

glycerol kinase 3 pseudogene

FunCoup

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Ensembl

ENSG00000229894

UniProt

Q14409

NCBI

GPI

glucose-6-phosphate isomerase

FunCoup

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Ensembl

ENSG00000105220

UniProt

NCBI

2821

GPAM

glycerol-3-phosphate acyltransferase, mitochondrial

FunCoup

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Ensembl

ENSG00000119927

UniProt

NCBI

57678

Query genes

		Identifier	Description
30	ENSG00000197142	ENSG00000197142	acyl-CoA synthetase long chain family member 5
		UniProt	Q9ULC5
		NCBI	51703
		KEGG signaling	Adipocytokine signaling pathway PPAR signaling pathway
		KEGG metabolic	Peroxisome Fatty acid biosynthesis Fatty acid degradation Fatty acid metabolism

Subnetwork genes

		Identifier	Description
27	TKT	ENSG00000163931	transketolase
		UniProt	A0A0B4J1R6 E9PFF2 F8W888 F8WAX4 P29401
		NCBI	7086
		KEGG metabolic	Pentose phosphate pathway Biosynthesis of amino acids Carbon metabolism
28	GRPEL1	ENSG00000109519	GrpE like 1, mitochondrial
		UniProt	Q9HAV7
		NCBI	80273
20	GK2	ENSG00000196475	glycerol kinase 2
		UniProt	Q14410
		NCBI	2712
		KEGG signaling	PPAR signaling pathway
		KEGG metabolic	Glycerolipid metabolism
26	GK	ENSG00000198814	glycerol kinase
		UniProt	A6NP46 F8WBI8 F8WC39 F8WDA9 F8WF44 H7BYD2 H7C2A0 H7C5F6 P32189
		NCBI	2710
		KEGG signaling	PPAR signaling pathway
		KEGG metabolic	Glycerolipid metabolism
28	CYB5R3	ENSG00000100243	cytochrome b5 reductase 3
		UniProt	B1AHF3 P00387
		NCBI	1727
		KEGG metabolic	Amino sugar and nucleotide sugar metabolism
28	ATP5F1A	ENSG00000152234	ATP synthase F1 subunit alpha
		UniProt	A0A0A0MTS3 K7EJP1 K7EK77 K7EKV9 K7EM08 K7ENJ4 K7EQH4 K7EQU6 K7ERX7 K7ESA0 P25705
		NCBI	498
		KEGG metabolic	Oxidative phosphorylation
25	CYB5A	ENSG00000166347	cytochrome b5 type A
		UniProt	J3KNC7 P00167
		NCBI	1528
26	C1QBP	ENSG00000108561	complement C1q binding protein
		UniProt	A0A0G2JLC0 I3L3B0 I3L3Q7 Q07021
		NCBI	708
27	ATP5F1C	ENSG00000165629	ATP synthase F1 subunit gamma
		UniProt	P36542
		NCBI	509
		KEGG metabolic	Oxidative phosphorylation
26	EIF5A	ENSG00000132507	eukaryotic translation initiation factor 5A
		UniProt	I3L397 I3L504 P63241
		NCBI	1984
25	COPG1	ENSG00000181789	COPI coat complex subunit gamma 1
		UniProt	D6RG17 H0Y8G2 H0Y8X7 Q9Y678
		NCBI	22820
29	PMPCB	ENSG00000105819	peptidase, mitochondrial processing subunit beta
		UniProt	F8WAZ6 F8WBE1 F8WEA6 F8WEC8 G3V0E4 O75439
		NCBI	9512
28	ATP5F1B	ENSG00000110955	ATP synthase F1 subunit beta
		UniProt	F8W079 F8W0P7 H0YH81 H0YI37 P06576
		NCBI	506
		KEGG metabolic	Oxidative phosphorylation
26	HSP90B1	ENSG00000166598	heat shock protein 90 beta family member 1
		UniProt	A0A1W2PRR1 F8VPC7 F8W026 H0YIV0 P14625 Q96GW1
		NCBI	7184
		KEGG signaling	PI3K-Akt signaling pathway Estrogen signaling pathway IL-17 signaling pathway
		KEGG metabolic	Protein processing in endoplasmic reticulum
28	NME1	ENSG00000239672	NME/NM23 nucleoside diphosphate kinase 1
		UniProt	C9K028 E5RHP0 E7ERL0 P15531
		NCBI	4830
		KEGG metabolic	Drug metabolism - other enzymes Purine metabolism Pyrimidine metabolism
28	HSPA9	ENSG00000113013	heat shock protein family A (Hsp70) member 9
		UniProt	A0A3B3ITI4 A0A3B3ITN1 D6RA73 D6RCD7 D6RDH7 D6RJI2 H0Y8K0 H0Y8S0 H0YBG6 P38646
		NCBI	3313
		KEGG metabolic	RNA degradation
27	ATP5PO	ENSG00000241837	ATP synthase peripheral stalk subunit OSCP
		UniProt	A0A494C0K9 H7C068 H7C086 H7C239 H7C2P9 P48047
		NCBI	539
		KEGG metabolic	Oxidative phosphorylation
26	UBA1	ENSG00000130985	ubiquitin like modifier activating enzyme 1
		UniProt	P22314 Q5JRR6 Q5JRR9 Q5JRS0 Q5JRS1 Q5JRS2 Q5JRS3
		NCBI	7317
		KEGG metabolic	Ubiquitin mediated proteolysis
25	IDE	ENSG00000119912	insulin degrading enzyme
		UniProt	A0A3B3ISG5 P14735 Q5T5N3 R4GN65
		NCBI	3416
29	DNM1L	ENSG00000087470	dynamin 1 like
		UniProt	B4DDQ3 B4DPZ9 F8VR28 F8VUJ9 F8VYL3 F8VZ52 F8W1W3 H0YHY4 H0YI79 O00429
		NCBI	10059
		KEGG signaling	NOD-like receptor signaling pathway TNF signaling pathway
25	CAT	ENSG00000121691	catalase
		UniProt	A0A3B3ITJ0 P04040
		NCBI	847
		KEGG signaling	FoxO signaling pathway
		KEGG metabolic	Peroxisome Tryptophan metabolism Carbon metabolism Glyoxylate and dicarboxylate metabolism
24	RPS27A	ENSG00000143947	ribosomal protein S27a
		UniProt	J3QTR3 P62979 Q49A90
		NCBI	6233
		KEGG metabolic	Ubiquitin mediated proteolysis Ribosome
14	SNRPE	ENSG00000182004	small nuclear ribonucleoprotein polypeptide E
		UniProt	A6NHK2 P62304
		NCBI	6635
		KEGG metabolic	Spliceosome
29	AFG3L2	ENSG00000141385	AFG3 like matrix AAA peptidase subunit 2
		UniProt	K7EP56 Q9Y4W6
		NCBI	10939
28	SDHB	ENSG00000117118	succinate dehydrogenase complex iron sulfur subunit B
		UniProt	A0A087WWT1 A0A087WXX8 P21912
		NCBI	6390
		KEGG metabolic	Oxidative phosphorylation Citrate cycle (TCA cycle) Carbon metabolism
1	CREB3	ENSG00000107175	cAMP responsive element binding protein 3
		UniProt	O43889
		NCBI	10488
		KEGG signaling	cAMP signaling pathway cGMP-PKG signaling pathway Melanogenesis AMPK signaling pathway Relaxin signaling pathway Estrogen signaling pathway Dopaminergic synapse Adrenergic signaling in cardiomyocytes PI3K-Akt signaling pathway Cholinergic synapse Glucagon signaling pathway TNF signaling pathway
22	LPIN1	ENSG00000134324	lipin 1
		UniProt	A0A0A0MS66 C9IYP2 C9J278 H7C3T1 Q14693
		NCBI	23175
		KEGG signaling	mTOR signaling pathway
		KEGG metabolic	Glycerolipid metabolism Glycerophospholipid metabolism
21	GK3P	ENSG00000229894	glycerol kinase 3 pseudogene
		UniProt	Q14409
28	GPI	ENSG00000105220	glucose-6-phosphate isomerase
		UniProt	A0A0G2JLI6 A0A2R8Y6C7 A0A2R8YF08 A0A2U3TZU2 K7EIL4 K7ELR7 K7ENA0 K7EP41 K7EPY4 K7EQ48 K7ERC6 K7ERK8 P06744
		NCBI	2821
		KEGG metabolic	Starch and sucrose metabolism Pentose phosphate pathway Glycolysis / Gluconeogenesis Carbon metabolism Amino sugar and nucleotide sugar metabolism
12	GPAM	ENSG00000119927	glycerol-3-phosphate acyltransferase, mitochondrial
		UniProt	Q5VW52 Q9HCL2
		NCBI	57678
		KEGG metabolic	Glycerolipid metabolism Glycerophospholipid metabolism

Enrichment analysis

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	jSquid_subnetworks.xml	318.50 KB
	H.sapiens_subnetwork.tsv	74.92 KB

Species:

Network information:

Filter Results:

Network appearance:

ENSG00000197142

TKT

GRPEL1

GK2

GK

CYB5R3

ATP5F1A

CYB5A

C1QBP

ATP5F1C

EIF5A

COPG1

PMPCB

ATP5F1B

HSP90B1

NME1

HSPA9

ATP5PO

UBA1

IDE

DNM1L

CAT

RPS27A

SNRPE

AFG3L2

SDHB

CREB3

LPIN1

GK3P

GPI

GPAM

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