Found 1 of 1 query genes
Query interactions
- Interaction partners
- Confidence
- Network
- Evidence types
- SpeciesHSAMMURNOCFAGGADRECINDMECELBTASCEATHSPOBSUECOPFADDISSOSSCMJAOSA
- In Gold st.
- ID Query gene
- ID Query ortholog
Log-likelihood ratio (LLR) | |
---|---|
Highly positive | |
Positive | |
Zero | |
Negative | |
Highly negative | |
Known coupling | |
This network | |
Other network |
-
- ENSG00000186088
- gamma-secretase activat…
- NCSTN
- nicastrin
- 0.969
- PPI
- PSEN1
- presenilin 1
- 0.960
- PPI
- PSENEN
- presenilin enhancer, ga…
- 0.935
- PPI
- APP
- amyloid beta precursor …
- 0.925
- PPI
Subnetwork gene interactions
ENSG00000186088
gamma-secretase activating protein
FunCoup
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- Ensembl
- UniProt
- NCBI
NCSTN
nicastrin
FunCoup
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- Use pair as query
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- Ensembl
- UniProt
- NCBI
APP
amyloid beta precursor protein
FunCoup
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- Use pair as query
- Add to current query
- Ensembl
- UniProt
- NCBI
PSEN1
presenilin 1
FunCoup
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- Add to current query
- Ensembl
- UniProt
- E7ES96
- G3V2B1
- G3V2G7
- G3V3P0
- G3V3Z0
- G3V449
- G3V490
- G3V499
- G3V4M0
- G3V4P4
- G3V519
- G3V5B1
- H0YM52
- H0YNU4
- P49768
- NCBI
PSENEN
presenilin enhancer, gamma-secretase subunit
FunCoup
- Use as query
- Use pair as query
- Add to current query
- Ensembl
- UniProt
- NCBI
Query genes
Subnetwork genes
Symbol | Identifier | Description | |||
---|---|---|---|---|---|
4
|
NCSTN | ENSG00000162736 | nicastrin | ||
| A0A2R8YCK1 A0A2R8YE20 A0A2U3TZL9 H0Y3Z4 H0Y6T7 Q5T205 Q5T209 Q5T210 Q5T211 Q92542 | ||||
| 23385 | ||||
| Notch signaling pathway | ||||
3
|
APP | ENSG00000142192 | amyloid beta precursor protein | ||
| A0A0A0MRG2 E9PG40 H7C0V9 H7C2L2 P05067 | ||||
| 351 | ||||
| Serotonergic synapse | ||||
4
|
PSEN1 | ENSG00000080815 | presenilin 1 | ||
| E7ES96 G3V2B1 G3V2G7 G3V3P0 G3V3Z0 G3V449 G3V490 G3V499 G3V4M0 G3V4P4 G3V519 G3V5B1 H0YM52 H0YNU4 P49768 | ||||
| 5663 | ||||
| Neurotrophin signaling pathway Wnt signaling pathway Notch signaling pathway | ||||
3
|
PSENEN | ENSG00000205155 | presenilin enhancer, gamma-secretase subunit | ||
| K7ES79 Q9NZ42 | ||||
| 55851 | ||||
| Notch signaling pathway |
Enrichment analysis
Search for enrichment of pathways or functional gene sets for your subnetwork genes | ||
To use PathwAX, first use the button below to copy the subnetwork genes and then paste them in PathwAX | ||
Copied subnetwork genes to clipboard
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jSquid_subnetworks.xml | 87.65 KB | |
H.sapiens_subnetwork.tsv | 1.96 KB |