Found 1 of 1 query genes

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Query interactions

Interaction partners
Confidence
Network
MEX
PIN
SCL
PHP
MIR
TFB
PEX
GIN
DOM
QMS
GRG
Evidence types
HSA
MMU
RNO
CFA
GGA
DRE
CIN
DME
CEL
BTA
SCE
ATH
SPO
BSU
ECO
PFA
DDI
SSO
SSC
MJA
OSA
Species
In Gold st.

ID Query gene
ID Query ortholog

Log-likelihood ratio (LLR)
	Highly positive
	Positive
	Zero
	Negative
	Highly negative
Known coupling
	This network
	Other network

2. ENSG00000182512
3. glutaredoxin 5
- 2. BOLA1
  3. bolA family member 1
  4. 1.000
  5. Complex
- 2. PMPCB
  3. peptidase, mitochondria…
  4. 1.000
  5. Complex
- 2. HSPA9
  3. heat shock protein fami…
  4. 1.000
  5. PPI
- 2. GFM1
  3. G elongation factor mit…
  4. 1.000
  5. Complex
- 2. PMPCA
  3. peptidase, mitochondria…
  4. 1.000
  5. Complex
- 2. C1QBP
  3. complement C1q binding …
  4. 1.000
  5. Complex
- 2. BOLA3
  3. bolA family member 3
  4. 1.000
  5. PPI
- 2. CHCHD2
  3. coiled-coil-helix-coile…
  4. 1.000
  5. PPI
- 2. ATP5F1A
  3. ATP synthase F1 subunit…
  4. 1.000
  5. PPI
- 2. HSP90AA1
  3. heat shock protein 90 a…
  4. 0.999
  5. Metabolic
- 2. NDUFS3
  3. NADH:ubiquinone oxidore…
  4. 0.999
  5. PPI
- 2. DHRS4
  3. dehydrogenase/reductase…
  4. 0.999
  5. PPI
- 2. BCKDHA
  3. branched chain keto aci…
  4. 0.999
  5. Complex
- 2. SUCLA2
  3. succinate-CoA ligase AD…
  4. 0.999
  5. Complex
- 2. SDHAF3
  3. succinate dehydrogenase…
  4. 0.999
  5. PPI
- 2. CHCHD10
  3. coiled-coil-helix-coile…
  4. 0.999
  5. PPI
- 2. VDAC2
  3. voltage dependent anion…
  4. 0.999
  5. PPI
- 2. SHMT2
  3. serine hydroxymethyltra…
  4. 0.998
  5. Complex
- 2. HSCB
  3. HscB mitochondrial iron…
  4. 0.997
  5. PPI
- 2. TXN2
  3. thioredoxin 2
  4. 0.997
  5. Metabolic
- 2. NDUFS6
  3. NADH:ubiquinone oxidore…
  4. 0.997
  5. Complex
- 2. CISD3
  3. CDGSH iron sulfur domai…
  4. 0.997
  5. PPI
- 2. HDAC1
  3. histone deacetylase 1
  4. 0.996
  5. Metabolic
- 2. ETFA
  3. electron transfer flavo…
  4. 0.996
  5. Metabolic
- 2. SLC25A5
  3. solute carrier family 2…
  4. 0.995
  5. PPI
- 2. CPOX
  3. coproporphyrinogen oxid…
  4. 0.995
  5. Metabolic
- 2. ETFB
  3. electron transfer flavo…
  4. 0.995
  5. Metabolic
- 2. GCSH
  3. glycine cleavage system…
  4. 0.995
  5. Metabolic
- 2. SOD1
  3. superoxide dismutase 1
  4. 0.994
  5. Metabolic
- 2. TPI1
  3. triosephosphate isomera…
  4. 0.993
  5. Metabolic

Subnetwork gene interactions

ENSG00000182512

glutaredoxin 5

FunCoup

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Ensembl

ENSG00000182512

UniProt

NCBI

51218

VDAC2

voltage dependent anion channel 2

FunCoup

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Ensembl

ENSG00000165637

UniProt

NCBI

7417

SOD1

superoxide dismutase 1

FunCoup

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Ensembl

ENSG00000142168

UniProt

NCBI

6647

HDAC1

histone deacetylase 1

FunCoup

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Ensembl

ENSG00000116478

UniProt

NCBI

3065

NDUFS3

NADH:ubiquinone oxidoreductase core subunit S3

FunCoup

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Ensembl

ENSG00000213619

UniProt

NCBI

4722

SLC25A5

solute carrier family 25 member 5

FunCoup

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Ensembl

ENSG00000005022

UniProt

P05141

NCBI

C1QBP

complement C1q binding protein

FunCoup

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Ensembl

ENSG00000108561

UniProt

NCBI

CHCHD10

coiled-coil-helix-coiled-coil-helix domain containing 10

FunCoup

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Ensembl

ENSG00000250479

UniProt

NCBI

400916

HSPA9

heat shock protein family A (Hsp70) member 9

FunCoup

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Ensembl

ENSG00000113013

UniProt

NCBI

3313

HSCB

HscB mitochondrial iron-sulfur cluster cochaperone

FunCoup

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Ensembl

ENSG00000100209

UniProt

NCBI

150274

PMPCA

peptidase, mitochondrial processing subunit alpha

FunCoup

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Ensembl

ENSG00000165688

UniProt

NCBI

23203

PMPCB

peptidase, mitochondrial processing subunit beta

FunCoup

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Ensembl

ENSG00000105819

UniProt

NCBI

9512

NDUFS6

NADH:ubiquinone oxidoreductase subunit S6

FunCoup

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Ensembl

ENSG00000145494

UniProt

NCBI

4726

ETFB

electron transfer flavoprotein subunit beta

FunCoup

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Ensembl

ENSG00000105379

UniProt

NCBI

2109

GFM1

G elongation factor mitochondrial 1

FunCoup

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Ensembl

ENSG00000168827

UniProt

NCBI

85476

BCKDHA

branched chain keto acid dehydrogenase E1 subunit alpha

FunCoup

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Ensembl

ENSG00000248098

UniProt

NCBI

SHMT2

serine hydroxymethyltransferase 2

FunCoup

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Ensembl

ENSG00000182199

UniProt

NCBI

6472

TPI1

triosephosphate isomerase 1

FunCoup

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Ensembl

ENSG00000111669

UniProt

NCBI

7167

CHCHD2

coiled-coil-helix-coiled-coil-helix domain containing 2

FunCoup

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Ensembl

ENSG00000106153

UniProt

Q9Y6H1

NCBI

51142

SUCLA2

succinate-CoA ligase ADP-forming subunit beta

FunCoup

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Ensembl

ENSG00000136143

UniProt

NCBI

8803

DHRS4

dehydrogenase/reductase 4

FunCoup

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Ensembl

ENSG00000157326

UniProt

NCBI

10901

ETFA

electron transfer flavoprotein subunit alpha

FunCoup

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Ensembl

ENSG00000140374

UniProt

NCBI

2108

SDHAF3

succinate dehydrogenase complex assembly factor 3

FunCoup

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Ensembl

ENSG00000196636

UniProt

NCBI

57001

HSP90AA1

heat shock protein 90 alpha family class A member 1

FunCoup

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Ensembl

ENSG00000080824

UniProt

NCBI

3320

CISD3

CDGSH iron sulfur domain 3

FunCoup

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Ensembl

ENSG00000277972

UniProt

P0C7P0

NCBI

284106

BOLA3

bolA family member 3

FunCoup

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Ensembl

ENSG00000163170

UniProt

Q53S33

NCBI

388962

CPOX

coproporphyrinogen oxidase

FunCoup

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Ensembl

ENSG00000080819

UniProt

NCBI

1371

BOLA1

bolA family member 1

FunCoup

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Ensembl

ENSG00000178096

UniProt

Q9Y3E2

NCBI

51027

ATP5F1A

ATP synthase F1 subunit alpha

FunCoup

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Ensembl

ENSG00000152234

UniProt

NCBI

TXN2

thioredoxin 2

FunCoup

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Ensembl

ENSG00000100348

UniProt

NCBI

25828

GCSH

glycine cleavage system protein H

FunCoup

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Ensembl

ENSG00000140905

UniProt

NCBI

2653

Query genes

		Identifier	Description
30	ENSG00000182512	ENSG00000182512	glutaredoxin 5
		UniProt	H0YJM6 Q86SX6
		NCBI	51218

Subnetwork genes

		Identifier	Description
30	VDAC2	ENSG00000165637	voltage dependent anion channel 2
		UniProt	A0A0A0MR02 A2A3S1 P45880 Q5JSD1 Q5JSD2
		NCBI	7417
		KEGG signaling	NOD-like receptor signaling pathway cGMP-PKG signaling pathway Calcium signaling pathway
27	SOD1	ENSG00000142168	superoxide dismutase 1
		UniProt	H7BYH4 P00441
		NCBI	6647
		KEGG metabolic	Peroxisome
16	HDAC1	ENSG00000116478	histone deacetylase 1
		UniProt	Q13547 Q5TEE2
		NCBI	3065
		KEGG signaling	Thyroid hormone signaling pathway Cell cycle Notch signaling pathway
26	NDUFS3	ENSG00000213619	NADH:ubiquinone oxidoreductase core subunit S3
		UniProt	E9PJE7 E9PKL8 E9PS48 G3V194 O75489
		NCBI	4722
		KEGG signaling	Retrograde endocannabinoid signaling
		KEGG metabolic	Oxidative phosphorylation
28	SLC25A5	ENSG00000005022	solute carrier family 25 member 5
		UniProt	P05141
		NCBI	292
		KEGG signaling	cGMP-PKG signaling pathway Calcium signaling pathway
29	C1QBP	ENSG00000108561	complement C1q binding protein
		UniProt	A0A0G2JLC0 I3L3B0 I3L3Q7 Q07021
		NCBI	708
20	CHCHD10	ENSG00000250479	coiled-coil-helix-coiled-coil-helix domain containing 10
		UniProt	B5MBW9 E5RGN4 E5RH03 Q8WYQ3
		NCBI	400916
28	HSPA9	ENSG00000113013	heat shock protein family A (Hsp70) member 9
		UniProt	A0A3B3ITI4 A0A3B3ITN1 D6RA73 D6RCD7 D6RDH7 D6RJI2 H0Y8K0 H0Y8S0 H0YBG6 P38646
		NCBI	3313
		KEGG metabolic	RNA degradation
6	HSCB	ENSG00000100209	HscB mitochondrial iron-sulfur cluster cochaperone
		UniProt	B0QYH2 F8WBY7 Q8IWL3
		NCBI	150274
29	PMPCA	ENSG00000165688	peptidase, mitochondrial processing subunit alpha
		UniProt	Q10713 Q5SXN9
		NCBI	23203
28	PMPCB	ENSG00000105819	peptidase, mitochondrial processing subunit beta
		UniProt	F8WAZ6 F8WBE1 F8WEA6 F8WEC8 G3V0E4 O75439
		NCBI	9512
24	NDUFS6	ENSG00000145494	NADH:ubiquinone oxidoreductase subunit S6
		UniProt	D6RBT3 O75380
		NCBI	4726
		KEGG signaling	Retrograde endocannabinoid signaling
		KEGG metabolic	Oxidative phosphorylation
28	ETFB	ENSG00000105379	electron transfer flavoprotein subunit beta
		UniProt	M0QY67 P38117
		NCBI	2109
25	GFM1	ENSG00000168827	G elongation factor mitochondrial 1
		UniProt	C9IZ01 C9JA25 F8WAU4 H7C5M4 Q96RP9
		NCBI	85476
20	BCKDHA	ENSG00000248098	branched chain keto acid dehydrogenase E1 subunit alpha
		UniProt	F5GXU9 H0YH20 H0YH31 P12694
		NCBI	593
		KEGG metabolic	Valine, leucine and isoleucine degradation Propanoate metabolism
28	SHMT2	ENSG00000182199	serine hydroxymethyltransferase 2
		UniProt	G3V241 G3V2D2 G3V2E4 G3V2W0 G3V2Y1 G3V2Y4 G3V3C6 G3V3Y8 G3V4T0 G3V4W5 G3V4X0 G3V540 G3V5L0 H0YIZ0 P34897
		NCBI	6472
		KEGG metabolic	Glycine, serine and threonine metabolism One carbon pool by folate Biosynthesis of amino acids Carbon metabolism Glyoxylate and dicarboxylate metabolism
27	TPI1	ENSG00000111669	triosephosphate isomerase 1
		UniProt	P60174 U3KPS5 U3KPZ0 U3KQF3
		NCBI	7167
		KEGG metabolic	Fructose and mannose metabolism Glycolysis / Gluconeogenesis Biosynthesis of amino acids Inositol phosphate metabolism Carbon metabolism
24	CHCHD2	ENSG00000106153	coiled-coil-helix-coiled-coil-helix domain containing 2
		UniProt	Q9Y6H1
		NCBI	51142
26	SUCLA2	ENSG00000136143	succinate-CoA ligase ADP-forming subunit beta
		UniProt	A0A0U1RQF8 A0A0U1RQL1 A0A0U1RQU7 A0A0U1RRI1 A0A2R8Y5P4 A0A2R8Y5P6 A0A2R8Y6E6 A0A2R8Y6Y7 A0A2R8YDQ9 A0A2R8YF84 Q5T9Q5 Q5T9Q8 Q9P2R7
		NCBI	8803
		KEGG metabolic	Citrate cycle (TCA cycle) Carbon metabolism Propanoate metabolism
23	DHRS4	ENSG00000157326	dehydrogenase/reductase 4
		UniProt	F5GWZ1 H0YNP7 Q9BTZ2
		NCBI	10901
		KEGG metabolic	Retinol metabolism Peroxisome
28	ETFA	ENSG00000140374	electron transfer flavoprotein subunit alpha
		UniProt	H0YK49 H0YKF0 H0YL12 H0YL83 H0YLU7 H0YM12 H0YMU8 H0YNX6 H3BV91 J3KN60 P13804
		NCBI	2108
16	SDHAF3	ENSG00000196636	succinate dehydrogenase complex assembly factor 3
		UniProt	F8W9V1 Q9NRP4
		NCBI	57001
20	HSP90AA1	ENSG00000080824	heat shock protein 90 alpha family class A member 1
		UniProt	A0A0U1RR69 G3V2J8 G3V592 H0YJF5 P07900
		NCBI	3320
		KEGG signaling	Antigen processing and presentation NOD-like receptor signaling pathway PI3K-Akt signaling pathway Estrogen signaling pathway Progesterone-mediated oocyte maturation IL-17 signaling pathway
		KEGG metabolic	Protein processing in endoplasmic reticulum
11	CISD3	ENSG00000277972	CDGSH iron sulfur domain 3
		UniProt	P0C7P0
		NCBI	284106
22	BOLA3	ENSG00000163170	bolA family member 3
		UniProt	Q53S33
		NCBI	388962
19	CPOX	ENSG00000080819	coproporphyrinogen oxidase
		UniProt	D6RER6 P36551
		NCBI	1371
		KEGG metabolic	Porphyrin and chlorophyll metabolism
17	BOLA1	ENSG00000178096	bolA family member 1
		UniProt	Q9Y3E2
		NCBI	51027
26	ATP5F1A	ENSG00000152234	ATP synthase F1 subunit alpha
		UniProt	A0A0A0MTS3 K7EJP1 K7EK77 K7EKV9 K7EM08 K7ENJ4 K7EQH4 K7EQU6 K7ERX7 K7ESA0 P25705
		NCBI	498
		KEGG metabolic	Oxidative phosphorylation
19	TXN2	ENSG00000100348	thioredoxin 2
		UniProt	F8WDN2 M0QXH0 Q99757
		NCBI	25828
		KEGG signaling	NOD-like receptor signaling pathway
24	GCSH	ENSG00000140905	glycine cleavage system protein H
		UniProt	A0A1W2PNX3 A0A1W2PQV2 A0A1W2PQX3 H3BNV1 H3BPF0 H3BQ30 H3BUG8 H3BUH9 P23434
		NCBI	2653
		KEGG metabolic	Glycine, serine and threonine metabolism Carbon metabolism Glyoxylate and dicarboxylate metabolism

Enrichment analysis

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	jSquid_subnetworks.xml	312.00 KB
	H.sapiens_subnetwork.tsv	67.62 KB

Species:

Network information:

Filter Results:

Network appearance:

ENSG00000182512

VDAC2

SOD1

HDAC1

NDUFS3

SLC25A5

C1QBP

CHCHD10

HSPA9

HSCB

PMPCA

PMPCB

NDUFS6

ETFB

GFM1

BCKDHA

SHMT2

TPI1

CHCHD2

SUCLA2

DHRS4

ETFA

SDHAF3

HSP90AA1

CISD3

BOLA3

CPOX

BOLA1

ATP5F1A

TXN2

GCSH

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