Found 1 of 1 query genes

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Query interactions

Interaction partners
Confidence
Network
MEX
PIN
SCL
PHP
MIR
TFB
PEX
GIN
DOM
QMS
GRG
Evidence types
HSA
MMU
RNO
CFA
GGA
DRE
CIN
DME
CEL
BTA
SCE
ATH
SPO
BSU
ECO
PFA
DDI
SSO
SSC
MJA
OSA
Species
In Gold st.

ID Query gene
ID Query ortholog

Log-likelihood ratio (LLR)
	Highly positive
	Positive
	Zero
	Negative
	Highly negative
Known coupling
	This network
	Other network

2. ENSG00000182325
3. F-box and leucine rich …
- 2. CDC42
  3. cell division cycle 42
  4. 1.000
  5. PPI
- 2. CASK
  3. calcium/calmodulin depe…
  4. 0.999
  5. PPI
- 2. CUL1
  3. cullin 1
  4. 0.999
  5. PPI
- 2. CSNK1A1
  3. casein kinase 1 alpha 1
  4. 0.992
  5. PPI
- 2. SKP1
  3. S-phase kinase associat…
  4. 0.978
  5. PPI
- 2. KPNA6
  3. karyopherin subunit alp…
  4. 0.944
  5. Complex
- 2. NAA10
  3. N-alpha-acetyltransfera…
  4. 0.870
  5. PPI
- 2. UBE2A
  3. ubiquitin conjugating e…
  4. 0.868
  5. PPI
- 2. EHMT1
  3. euchromatic histone lys…
  4. 0.825
  5. Complex
- 2. THAP11
  3. THAP domain containing …
  4. 0.798
  5. Complex
- 2. GSK3B
  3. glycogen synthase kinas…
  4. 0.490
  5. Metabolic
- 2. ANAPC2
  3. anaphase promoting comp…
  4. 0.437
  5. Metabolic
- 2. TSC1
  3. TSC complex subunit 1
  4. 0.401
  5. Complex

Subnetwork gene interactions

ENSG00000182325

F-box and leucine rich repeat protein 6

FunCoup

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Ensembl

ENSG00000182325

UniProt

Q8N531

NCBI

26233

CDC42

cell division cycle 42

FunCoup

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Ensembl

ENSG00000070831

UniProt

NCBI

SKP1

S-phase kinase associated protein 1

FunCoup

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Ensembl

ENSG00000113558

UniProt

NCBI

6500

CUL1

cullin 1

FunCoup

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Ensembl

ENSG00000055130

UniProt

NCBI

8454

ANAPC2

anaphase promoting complex subunit 2

FunCoup

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Ensembl

ENSG00000176248

UniProt

Q9UJX6

NCBI

29882

CSNK1A1

casein kinase 1 alpha 1

FunCoup

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Ensembl

ENSG00000113712

UniProt

NCBI

1452

UBE2A

ubiquitin conjugating enzyme E2 A

FunCoup

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Ensembl

ENSG00000077721

UniProt

NCBI

7319

KPNA6

karyopherin subunit alpha 6

FunCoup

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Ensembl

ENSG00000025800

UniProt

NCBI

23633

GSK3B

glycogen synthase kinase 3 beta

FunCoup

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Ensembl

ENSG00000082701

UniProt

NCBI

2932

THAP11

THAP domain containing 11

FunCoup

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Ensembl

ENSG00000168286

UniProt

Q96EK4

NCBI

57215

EHMT1

euchromatic histone lysine methyltransferase 1

FunCoup

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Ensembl

ENSG00000181090

UniProt

NCBI

79813

TSC1

TSC complex subunit 1

FunCoup

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Ensembl

ENSG00000165699

UniProt

NCBI

7248

NAA10

N-alpha-acetyltransferase 10, NatA catalytic subunit

FunCoup

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Ensembl

ENSG00000102030

UniProt

NCBI

8260

CASK

calcium/calmodulin dependent serine protein kinase

FunCoup

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Ensembl

ENSG00000147044

UniProt

NCBI

8573

Query genes

		Identifier	Description
13	ENSG00000182325	ENSG00000182325	F-box and leucine rich repeat protein 6
		UniProt	Q8N531
		NCBI	26233

Subnetwork genes

		Identifier	Description
4	CDC42	ENSG00000070831	cell division cycle 42
		UniProt	A0A3B3IRV0 A0A494BZX6 A0A494C1M1 A0A590UJK8 P60953 Q5JYX0
		NCBI	998
		KEGG signaling	Leukocyte transendothelial migration MAPK signaling pathway VEGF signaling pathway Chemokine signaling pathway Neurotrophin signaling pathway Fc gamma R-mediated phagocytosis Rap1 signaling pathway Focal adhesion Ras signaling pathway Adherens junction Tight junction T cell receptor signaling pathway GnRH signaling pathway
		KEGG metabolic	Endocytosis
9	SKP1	ENSG00000113558	S-phase kinase associated protein 1
		UniProt	E5RGM3 E5RGM4 E5RHM3 E5RJR5 E5RK33 E7ERH2 F8W8N3 P63208
		NCBI	6500
		KEGG signaling	Oocyte meiosis Wnt signaling pathway Cell cycle TGF-beta signaling pathway
		KEGG metabolic	Ubiquitin mediated proteolysis Protein processing in endoplasmic reticulum
4	CUL1	ENSG00000055130	cullin 1
		UniProt	A0A0C4DGX4 A0A590UJ21 A0A590UJ50 A0A590UJ56 A0A590UJ59 A0A590UJ97 A0A590UJA0 A0A590UJC4 A0A590UJM8 A0A590UJR3 A0A590UK34 Q13616
		NCBI	8454
		KEGG signaling	Oocyte meiosis Wnt signaling pathway Cell cycle Hedgehog signaling pathway TGF-beta signaling pathway
		KEGG metabolic	Ubiquitin mediated proteolysis Protein processing in endoplasmic reticulum
4	ANAPC2	ENSG00000176248	anaphase promoting complex subunit 2
		UniProt	Q9UJX6
		NCBI	29882
		KEGG signaling	Oocyte meiosis Cell cycle Progesterone-mediated oocyte maturation
		KEGG metabolic	Ubiquitin mediated proteolysis
4	CSNK1A1	ENSG00000113712	casein kinase 1 alpha 1
		UniProt	A0A590UJ43 A0A590UJQ7 A0A590UK94 A0A5F9W493 D6REM4 D6RGE5 E5RG27 E7ETM0 H0Y9X2 P48729 U3KPX3 U3KQ83 U3KQK7
		NCBI	1452
		KEGG signaling	Wnt signaling pathway Hedgehog signaling pathway
3	UBE2A	ENSG00000077721	ubiquitin conjugating enzyme E2 A
		UniProt	A0A0D9SEZ6 A0A0D9SF75 A0A0D9SG71 A0A0R4J2E5 P49459
		NCBI	7319
		KEGG metabolic	Ubiquitin mediated proteolysis
6	KPNA6	ENSG00000025800	karyopherin subunit alpha 6
		UniProt	O60684 Q5TFJ7 S4R3E5
		NCBI	23633
4	GSK3B	ENSG00000082701	glycogen synthase kinase 3 beta
		UniProt	A0A3B3ITW1 P49841
		NCBI	2932
		KEGG signaling	Thyroid hormone signaling pathway Hedgehog signaling pathway PI3K-Akt signaling pathway Chemokine signaling pathway mTOR signaling pathway Hippo signaling pathway Neurotrophin signaling pathway Focal adhesion Wnt signaling pathway B cell receptor signaling pathway ErbB signaling pathway Cell cycle T cell receptor signaling pathway Prolactin signaling pathway Melanogenesis Dopaminergic synapse IL-17 signaling pathway Insulin signaling pathway
4	THAP11	ENSG00000168286	THAP domain containing 11
		UniProt	Q96EK4
		NCBI	57215
3	EHMT1	ENSG00000181090	euchromatic histone lysine methyltransferase 1
		UniProt	A0A0C4DGF8 A0A0D9SEP2 A0A0D9SEQ1 A0A0D9SER3 A0A0D9SER9 A0A0D9SEY2 A0A0D9SF38 A0A0D9SFD7 A0A0D9SFG7 A0A0D9SFM6 A0A0D9SFS4 A0A0D9SFX4 A0A1B0GTP4 A0A1B0GU48 A0A1B0GUD1 A0A1B0GV09 A0A1B0GV89 A0A1B0GVZ8 A0A1B0GW12 A0A1B0GW79 A0A1B0GWF6 A0A1W2PPZ7 Q9H9B1
		NCBI	79813
		KEGG metabolic	Lysine degradation
2	TSC1	ENSG00000165699	TSC complex subunit 1
		UniProt	A0A2R8Y419 A0A2R8Y5F8 A0A2R8Y5J1 A0A2R8Y5M3 A0A2R8Y5N2 A0A2R8Y5Q4 A0A2R8Y5S3 A0A2R8Y5U8 A0A2R8Y6N1 A0A2R8Y6S1 A0A2R8Y6S8 A0A2R8Y6T5 A0A2R8Y6W1 A0A2R8Y756 A0A2R8Y7E9 A0A2R8YD74 A0A2R8YEH9 A0A2R8YFV7 A0A2R8YGL0 A0A2R8YGX7 Q59IT9 Q86WV8 Q92574
		NCBI	7248
		KEGG signaling	AMPK signaling pathway PI3K-Akt signaling pathway mTOR signaling pathway Phospholipase D signaling pathway Insulin signaling pathway
		KEGG metabolic	Autophagy - animal
3	NAA10	ENSG00000102030	N-alpha-acetyltransferase 10, NatA catalytic subunit
		UniProt	A8MWP7 C9JN83 C9JW55 F8W808 P41227
		NCBI	8260
1	CASK	ENSG00000147044	calcium/calmodulin dependent serine protein kinase
		UniProt	A0A2R8Y3B3 A0A2R8Y472 A0A2R8Y4K4 A0A2R8Y6D8 A0A2R8Y6F8 A0A2R8Y7X6 A0A2R8YE77 A0A2R8YEJ7 A0A2R8YEK3 A0A2R8YFN5 A0A2R8YGH2 A0A2U3TZM1 A0A2U3TZM4 A0A2U3TZN6 O14936 Q5JS72 Q5JS79
		NCBI	8573

Enrichment analysis

Search for enrichment of pathways or functional gene sets for your subnetwork genes

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	jSquid_subnetworks.xml	139.11 KB
	H.sapiens_subnetwork.tsv	5.91 KB

Species:

Network information:

Filter Results:

Network appearance:

ENSG00000182325

CDC42

SKP1

CUL1

ANAPC2

CSNK1A1

UBE2A

KPNA6

GSK3B

THAP11

EHMT1

TSC1

NAA10

CASK

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