Found 1 of 1 query genes

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Query interactions

Interaction partners
Confidence
Network
MEX
PIN
SCL
PHP
MIR
TFB
PEX
GIN
DOM
QMS
GRG
Evidence types
HSA
MMU
RNO
CFA
GGA
DRE
CIN
DME
CEL
BTA
SCE
ATH
SPO
BSU
ECO
PFA
DDI
SSO
SSC
MJA
OSA
Species
In Gold st.

ID Query gene
ID Query ortholog

Log-likelihood ratio (LLR)
	Highly positive
	Positive
	Zero
	Negative
	Highly negative
Known coupling
	This network
	Other network

2. ENSG00000176399
3. DMRT like family A1
- 2. PAWR
  3. pro-apoptotic WT1 regul…
  4. 0.921
  5. PPI
- 2. ACTB
  3. actin beta
  4. 0.839
  5. PPI
- 2. IRAK4
  3. interleukin 1 receptor …
  4. 0.834
  5. Complex
- 2. KRT8
  3. keratin 8
  4. 0.812
  5. PPI
- 2. UROD
  3. uroporphyrinogen decarb…
  4. 0.722
  5. PPI
- 2. HSP90B1
  3. heat shock protein 90 b…
  4. 0.703
  5. Metabolic
- 2. HSP90AA1
  3. heat shock protein 90 a…
  4. 0.642
  5. PPI
- 2. GFAP
  3. glial fibrillary acidic…
  4. 0.608
  5. PPI
- 2. EPB41L2
  3. erythrocyte membrane pr…
  4. 0.491
  5. Metabolic
- 2. DDX5
  3. DEAD-box helicase 5
  4. 0.443
  5. PPI
- 2. SYN1
  3. synapsin I
  4. 0.418
  5. PPI

Subnetwork gene interactions

ENSG00000176399

DMRT like family A1

FunCoup

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Ensembl

ENSG00000176399

UniProt

Q5VZB9

NCBI

63951

HSP90B1

heat shock protein 90 beta family member 1

FunCoup

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Ensembl

ENSG00000166598

UniProt

NCBI

7184

UROD

uroporphyrinogen decarboxylase

FunCoup

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Ensembl

ENSG00000126088

UniProt

NCBI

7389

KRT8

keratin 8

FunCoup

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Ensembl

ENSG00000170421

UniProt

NCBI

3856

DDX5

DEAD-box helicase 5

FunCoup

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Ensembl

ENSG00000108654

UniProt

NCBI

1655

EPB41L2

erythrocyte membrane protein band 4.1 like 2

FunCoup

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Ensembl

ENSG00000079819

UniProt

NCBI

2037

HSP90AA1

heat shock protein 90 alpha family class A member 1

FunCoup

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Ensembl

ENSG00000080824

UniProt

NCBI

3320

ACTB

actin beta

FunCoup

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Ensembl

ENSG00000075624

UniProt

NCBI

SYN1

synapsin I

FunCoup

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Ensembl

ENSG00000008056

UniProt

NCBI

6853

PAWR

pro-apoptotic WT1 regulator

FunCoup

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Ensembl

ENSG00000177425

UniProt

NCBI

5074

IRAK4

interleukin 1 receptor associated kinase 4

FunCoup

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Ensembl

ENSG00000198001

UniProt

NCBI

51135

GFAP

glial fibrillary acidic protein

FunCoup

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Ensembl

ENSG00000131095

UniProt

NCBI

2670

Query genes

		Identifier	Description
11	ENSG00000176399	ENSG00000176399	DMRT like family A1
		UniProt	Q5VZB9
		NCBI	63951

Subnetwork genes

		Identifier	Description
6	HSP90B1	ENSG00000166598	heat shock protein 90 beta family member 1
		UniProt	A0A1W2PRR1 F8VPC7 F8W026 H0YIV0 P14625 Q96GW1
		NCBI	7184
		KEGG signaling	PI3K-Akt signaling pathway Estrogen signaling pathway IL-17 signaling pathway
		KEGG metabolic	Protein processing in endoplasmic reticulum
5	UROD	ENSG00000126088	uroporphyrinogen decarboxylase
		UniProt	A0A1B0GVN9 A0A1B0GVZ4 A0A494BZV1 A0A494BZY8 A0A494C007 A0A494C085 A0A494C0P4 A0A494C0Q8 A0A494C0S8 A0A494C1D8 A0A494C1T3 H0Y5R6 P06132 Q5T446
		NCBI	7389
		KEGG metabolic	Porphyrin and chlorophyll metabolism
3	KRT8	ENSG00000170421	keratin 8
		UniProt	A0A0U1RQU6 F8VP67 F8VQY3 F8VUG2 F8W1U3 H0YIB2 P05787
		NCBI	3856
7	DDX5	ENSG00000108654	DEAD-box helicase 5
		UniProt	A0A0G2JLI4 J3KRX8 J3KRZ1 J3KTA4 J3KTQ4 J3QKN9 J3QLG9 J3QR02 J3QR62 J3QRN5 J3QRQ7 J3QS79 J3QS97 J3QSF1 K7EKV0 P17844 X6RLV5
		NCBI	1655
		KEGG metabolic	Spliceosome
4	EPB41L2	ENSG00000079819	erythrocyte membrane protein band 4.1 like 2
		UniProt	A0A2R8Y5B3 E9PHY5 E9PIG0 E9PII3 E9PJP4 E9PK52 E9PMG5 E9PMV8 E9PN54 E9PPC9 E9PQD2 E9PQN0 E9PRG1 H0Y5B0 O43491 Q6R5J7 Q6ZSX4
		NCBI	2037
5	HSP90AA1	ENSG00000080824	heat shock protein 90 alpha family class A member 1
		UniProt	A0A0U1RR69 G3V2J8 G3V592 H0YJF5 P07900
		NCBI	3320
		KEGG signaling	Antigen processing and presentation NOD-like receptor signaling pathway PI3K-Akt signaling pathway Estrogen signaling pathway Progesterone-mediated oocyte maturation IL-17 signaling pathway
		KEGG metabolic	Protein processing in endoplasmic reticulum
8	ACTB	ENSG00000075624	actin beta
		UniProt	A0A2R8Y793 A0A2R8YEA7 A0A2R8YFE2 A0A2R8YGF8 C9JTX5 C9JUM1 C9JZR7 E7EVS6 G5E9R0 P60709
		NCBI	60
		KEGG signaling	Focal adhesion Rap1 signaling pathway Adherens junction Tight junction Apoptosis Thyroid hormone signaling pathway Leukocyte transendothelial migration Hippo signaling pathway Oxytocin signaling pathway
		KEGG metabolic	Phagosome
2	SYN1	ENSG00000008056	synapsin I
		UniProt	A0A1W2PS00 A0A1W2PSE9 P17600
		NCBI	6853
1	PAWR	ENSG00000177425	pro-apoptotic WT1 regulator
		UniProt	A0A0B4J260 F8W1M8 H0YHP5 H0YI16 Q96IZ0
		NCBI	5074
1	IRAK4	ENSG00000198001	interleukin 1 receptor associated kinase 4
		UniProt	A0A0R4J2F4 F8VR40 F8VVZ1 F8VW24 Q9NWZ3
		NCBI	51135
		KEGG signaling	Neurotrophin signaling pathway NOD-like receptor signaling pathway Toll-like receptor signaling pathway MAPK signaling pathway NF-kappa B signaling pathway
1	GFAP	ENSG00000131095	glial fibrillary acidic protein
		UniProt	A0A0G2JLI8 A0A1W2PP21 A0A1W2PPA3 A0A1W2PPF0 A0A1W2PPL2 A0A1W2PQ25 A0A1W2PQS4 A0A1W2PQU7 A0A1W2PR46 A0A1W2PRT3 A0A1W2PS58 A0A1X7SBR3 A0A1X7SCE1 B4DIR1 K7EJK1 K7EJU1 K7EKD1 K7EKH9 K7ELP4 K7EPI4 K7EPT8 P14136
		NCBI	2670
		KEGG signaling	JAK-STAT signaling pathway

Enrichment analysis

Search for enrichment of pathways or functional gene sets for your subnetwork genes

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	jSquid_subnetworks.xml	117.13 KB
	H.sapiens_subnetwork.tsv	4.79 KB

Species:

Network information:

Filter Results:

Network appearance:

ENSG00000176399

HSP90B1

UROD

KRT8

DDX5

EPB41L2

HSP90AA1

ACTB

SYN1

PAWR

IRAK4

GFAP

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