- ID Query gene
- ID Query ortholog
Log-likelihood ratio (LLR) |
| Highly positive |
| Positive |
| Zero |
| Negative |
| Highly negative |
Known coupling |
| This network |
| Other network |
More
HMGCS2
- 3-hydroxy-3-methylgluta…
AGXT
- alanine--glyoxylate and…
GLUD1
- glutamate dehydrogenase…
GOT1
- glutamic-oxaloacetic tr…
D2HGDH
- D-2-hydroxyglutarate de…
AADAT
- aminoadipate aminotrans…
ALDH6A1
- aldehyde dehydrogenase …
ALDH2
- aldehyde dehydrogenase …
HUWE1
- HECT, UBA and WWE domai…
RAB5C
- RAB5C, member RAS oncog…
GLUD2
- glutamate dehydrogenase…
VDAC2
- voltage dependent anion…
ME3
- malic enzyme 3
CS
- citrate synthase
PYGL
- glycogen phosphorylase L
SUOX
- sulfite oxidase
PFKM
- phosphofructokinase, mu…
IDH3B
- isocitrate dehydrogenas…
P4HB
- prolyl 4-hydroxylase su…
RAB5B
- RAB5B, member RAS oncog…
PPA2
- inorganic pyrophosphata…
OAT
- ornithine aminotransfer…
IDH3A
- isocitrate dehydrogenas…
SHMT2
- serine hydroxymethyltra…
HMGCL
- 3-hydroxy-3-methylgluta…
PFKL
- phosphofructokinase, li…
UGP2
- UDP-glucose pyrophospho…
ALDH1B1
- aldehyde dehydrogenase …
ACO2
- aconitase 2
IDH3G
- isocitrate dehydrogenas…
ENSG00000173599
pyruvate carboxylase
- Use as query
- Use pair as query
- Add to current query
- Ensembl
- UniProt
- NCBI
HMGCS2
3-hydroxy-3-methylglutaryl-CoA synthase 2
- Use as query
- Use pair as query
- Add to current query
- Ensembl
- UniProt
- NCBI
AGXT
alanine--glyoxylate and serine--pyruvate aminotransferase
- Use as query
- Use pair as query
- Add to current query
- Ensembl
- UniProt
- NCBI
GLUD1
glutamate dehydrogenase 1
- Use as query
- Use pair as query
- Add to current query
- Ensembl
- UniProt
- NCBI
GOT1
glutamic-oxaloacetic transaminase 1
- Use as query
- Use pair as query
- Add to current query
- Ensembl
- UniProt
- NCBI
D2HGDH
D-2-hydroxyglutarate dehydrogenase
- Use as query
- Use pair as query
- Add to current query
- Ensembl
- UniProt
- NCBI
AADAT
aminoadipate aminotransferase
- Use as query
- Use pair as query
- Add to current query
- Ensembl
- UniProt
- NCBI
ALDH6A1
aldehyde dehydrogenase 6 family member A1
- Use as query
- Use pair as query
- Add to current query
- Ensembl
- UniProt
- NCBI
ALDH2
aldehyde dehydrogenase 2 family member
- Use as query
- Use pair as query
- Add to current query
- Ensembl
- UniProt
- NCBI
HUWE1
HECT, UBA and WWE domain containing E3 ubiquitin protein ligase 1
- Use as query
- Use pair as query
- Add to current query
- Ensembl
- UniProt
- NCBI
RAB5C
RAB5C, member RAS oncogene family
- Use as query
- Use pair as query
- Add to current query
- Ensembl
- UniProt
- NCBI
GLUD2
glutamate dehydrogenase 2
- Use as query
- Use pair as query
- Add to current query
- Ensembl
- UniProt
- NCBI
VDAC2
voltage dependent anion channel 2
- Use as query
- Use pair as query
- Add to current query
- Ensembl
- UniProt
- NCBI
ME3
malic enzyme 3
- Use as query
- Use pair as query
- Add to current query
- Ensembl
- UniProt
- NCBI
CS
citrate synthase
- Use as query
- Use pair as query
- Add to current query
- Ensembl
- UniProt
- NCBI
PYGL
glycogen phosphorylase L
- Use as query
- Use pair as query
- Add to current query
- Ensembl
- UniProt
- NCBI
SUOX
sulfite oxidase
- Use as query
- Use pair as query
- Add to current query
- Ensembl
- UniProt
- NCBI
PFKM
phosphofructokinase, muscle
- Use as query
- Use pair as query
- Add to current query
- Ensembl
- UniProt
- NCBI
IDH3B
isocitrate dehydrogenase (NAD(+)) 3 non-catalytic subunit beta
- Use as query
- Use pair as query
- Add to current query
- Ensembl
- UniProt
- NCBI
P4HB
prolyl 4-hydroxylase subunit beta
- Use as query
- Use pair as query
- Add to current query
- Ensembl
- UniProt
- NCBI
RAB5B
RAB5B, member RAS oncogene family
- Use as query
- Use pair as query
- Add to current query
- Ensembl
- UniProt
- NCBI
PPA2
inorganic pyrophosphatase 2
- Use as query
- Use pair as query
- Add to current query
- Ensembl
- UniProt
- NCBI
OAT
ornithine aminotransferase
- Use as query
- Use pair as query
- Add to current query
- Ensembl
- UniProt
- NCBI
IDH3A
isocitrate dehydrogenase (NAD(+)) 3 catalytic subunit alpha
- Use as query
- Use pair as query
- Add to current query
- Ensembl
- UniProt
- NCBI
SHMT2
serine hydroxymethyltransferase 2
- Use as query
- Use pair as query
- Add to current query
- Ensembl
- UniProt
- NCBI
HMGCL
3-hydroxy-3-methylglutaryl-CoA lyase
- Use as query
- Use pair as query
- Add to current query
- Ensembl
- UniProt
- NCBI
PFKL
phosphofructokinase, liver type
- Use as query
- Use pair as query
- Add to current query
- Ensembl
- UniProt
- NCBI
UGP2
UDP-glucose pyrophosphorylase 2
- Use as query
- Use pair as query
- Add to current query
- Ensembl
- UniProt
- NCBI
ALDH1B1
aldehyde dehydrogenase 1 family member B1
- Use as query
- Use pair as query
- Add to current query
- Ensembl
- UniProt
- NCBI
ACO2
aconitase 2
- Use as query
- Use pair as query
- Add to current query
- Ensembl
- UniProt
- NCBI
IDH3G
isocitrate dehydrogenase (NAD(+)) 3 non-catalytic subunit gamma
- Use as query
- Use pair as query
- Add to current query
- Ensembl
- UniProt
- NCBI
Symbol |
Identifier |
Description |
|
23
|
HMGCS2
|
ENSG00000134240
|
3-hydroxy-3-methylglutaryl-CoA synthase 2 |
|
| - UniProt
|
P54868
|
| - NCBI
|
3158
|
| - KEGG signaling
|
PPAR signaling pathway
|
| - KEGG metabolic
|
Terpenoid backbone biosynthesis
Synthesis and degradation of ketone bodies
Valine, leucine and isoleucine degradation
Butanoate metabolism
|
|
18
|
AGXT
|
ENSG00000172482
|
alanine--glyoxylate and serine--pyruvate aminotransferase |
|
| - UniProt
|
P21549
|
| - NCBI
|
189
|
| - KEGG metabolic
|
Peroxisome
Alanine, aspartate and glutamate metabolism
Glycine, serine and threonine metabolism
Carbon metabolism
Glyoxylate and dicarboxylate metabolism
|
|
29
|
GLUD1
|
ENSG00000148672
|
glutamate dehydrogenase 1 |
|
| - UniProt
|
P00367
|
| - NCBI
|
2746
|
| - KEGG metabolic
|
Nitrogen metabolism
Alanine, aspartate and glutamate metabolism
D-Glutamine and D-glutamate metabolism
Carbon metabolism
Arginine biosynthesis
|
|
21
|
GOT1
|
ENSG00000120053
|
glutamic-oxaloacetic transaminase 1 |
|
| - UniProt
|
P17174
|
| - NCBI
|
2805
|
| - KEGG metabolic
|
Phenylalanine, tyrosine and tryptophan biosynthesis
Cysteine and methionine metabolism
Phenylalanine metabolism
Alanine, aspartate and glutamate metabolism
Tyrosine metabolism
Biosynthesis of amino acids
Carbon metabolism
Arginine biosynthesis
Arginine and proline metabolism
2-Oxocarboxylic acid metabolism
|
|
16
|
D2HGDH
|
ENSG00000180902
|
D-2-hydroxyglutarate dehydrogenase |
|
| - UniProt
|
B5MCV2
F8WCF9
G5E9E8
H7C021
H7C0N1
H7C290
H7C3L2
Q8N465
|
| - NCBI
|
728294
|
|
19
|
AADAT
|
ENSG00000109576
|
aminoadipate aminotransferase |
|
| - UniProt
|
D6RC56
D6REB9
D6RFY7
Q8N5Z0
|
| - NCBI
|
51166
|
| - KEGG metabolic
|
Tryptophan metabolism
2-Oxocarboxylic acid metabolism
Lysine degradation
|
|
26
|
ALDH6A1
|
ENSG00000119711
|
aldehyde dehydrogenase 6 family member A1 |
|
| - UniProt
|
G3V4Z4
Q02252
|
| - NCBI
|
4329
|
| - KEGG metabolic
|
Valine, leucine and isoleucine degradation
Inositol phosphate metabolism
Carbon metabolism
beta-Alanine metabolism
Propanoate metabolism
|
|
29
|
ALDH2
|
ENSG00000111275
|
aldehyde dehydrogenase 2 family member |
|
| - UniProt
|
F8VSB0
P05091
S4R3S4
|
| - NCBI
|
217
|
| - KEGG metabolic
|
Pyruvate metabolism
Tryptophan metabolism
Fatty acid degradation
Valine, leucine and isoleucine degradation
Histidine metabolism
Glycolysis / Gluconeogenesis
Ascorbate and aldarate metabolism
Arginine and proline metabolism
Glycerolipid metabolism
beta-Alanine metabolism
Lysine degradation
|
|
13
|
HUWE1
|
ENSG00000086758
|
HECT, UBA and WWE domain containing E3 ubiquitin protein ligase 1 |
|
| - UniProt
|
A0A087X146
A0A087X1S3
A0A1B0GXC7
H0Y659
Q7Z6Z7
|
| - NCBI
|
10075
|
| - KEGG metabolic
|
Ubiquitin mediated proteolysis
|
|
19
|
RAB5C
|
ENSG00000108774
|
RAB5C, member RAS oncogene family |
|
| - UniProt
|
F8VSF8
F8VVK3
F8VWU4
K7ENY4
P51148
|
| - NCBI
|
5878
|
| - KEGG signaling
|
Ras signaling pathway
|
| - KEGG metabolic
|
Phagosome
Endocytosis
|
|
26
|
GLUD2
|
ENSG00000182890
|
glutamate dehydrogenase 2 |
|
| - UniProt
|
P49448
|
| - NCBI
|
2747
|
| - KEGG metabolic
|
Nitrogen metabolism
Alanine, aspartate and glutamate metabolism
D-Glutamine and D-glutamate metabolism
Carbon metabolism
Arginine biosynthesis
|
|
29
|
VDAC2
|
ENSG00000165637
|
voltage dependent anion channel 2 |
|
| - UniProt
|
A0A0A0MR02
A2A3S1
P45880
Q5JSD1
Q5JSD2
|
| - NCBI
|
7417
|
| - KEGG signaling
|
NOD-like receptor signaling pathway
cGMP-PKG signaling pathway
Calcium signaling pathway
|
|
26
|
ME3
|
ENSG00000151376
|
malic enzyme 3 |
|
| - UniProt
|
E9PKA0
E9PMB9
E9PND9
E9PNN2
Q16798
Q6TCH8
|
| - NCBI
|
10873
|
| - KEGG signaling
|
PPAR signaling pathway
|
| - KEGG metabolic
|
Pyruvate metabolism
Carbon metabolism
|
|
28
|
CS
|
ENSG00000062485
|
citrate synthase |
|
| - UniProt
|
A0A0C4DGI3
B4DJV2
F8VPA1
F8VPF9
F8VR34
F8VRI6
F8VRP1
F8VTT8
F8VU34
F8VVY4
F8VWQ5
F8VX07
F8VX68
F8VZK9
F8W0J2
F8W1S4
F8W4S1
F8W642
H0YH82
H0YIC4
O75390
|
| - NCBI
|
1431
|
| - KEGG metabolic
|
Biosynthesis of amino acids
Citrate cycle (TCA cycle)
Carbon metabolism
2-Oxocarboxylic acid metabolism
Glyoxylate and dicarboxylate metabolism
|
|
29
|
PYGL
|
ENSG00000100504
|
glycogen phosphorylase L |
|
| - UniProt
|
E9PK47
P06737
|
| - NCBI
|
5836
|
| - KEGG signaling
|
Glucagon signaling pathway
Insulin signaling pathway
|
| - KEGG metabolic
|
Starch and sucrose metabolism
|
|
19
|
SUOX
|
ENSG00000139531
|
sulfite oxidase |
|
| - UniProt
|
F8VPA2
F8VRK9
F8VVW9
F8VX56
P51687
|
| - NCBI
|
6821
|
| - KEGG metabolic
|
Sulfur metabolism
|
|
20
|
PFKM
|
ENSG00000152556
|
phosphofructokinase, muscle |
|
| - UniProt
|
A0A2R8Y891
F8VNZ1
F8VP00
F8VSF5
F8VSF7
F8VTQ3
F8VTT5
F8VUB8
F8VVE3
F8VW30
F8VX13
F8VYK8
F8VZ53
F8VZI0
F8VZQ1
H0YHB8
P08237
|
| - NCBI
|
5213
|
| - KEGG signaling
|
Thyroid hormone signaling pathway
HIF-1 signaling pathway
AMPK signaling pathway
Glucagon signaling pathway
|
| - KEGG metabolic
|
RNA degradation
Pentose phosphate pathway
Galactose metabolism
Fructose and mannose metabolism
Glycolysis / Gluconeogenesis
Biosynthesis of amino acids
Carbon metabolism
|
|
27
|
IDH3B
|
ENSG00000101365
|
isocitrate dehydrogenase (NAD(+)) 3 non-catalytic subunit beta |
|
| - UniProt
|
A0A087WZN1
A0A087X2E5
A0A0D9SET9
A0A0D9SG66
O43837
|
| - NCBI
|
3420
|
| - KEGG metabolic
|
Citrate cycle (TCA cycle)
Biosynthesis of amino acids
Carbon metabolism
2-Oxocarboxylic acid metabolism
|
|
25
|
P4HB
|
ENSG00000185624
|
prolyl 4-hydroxylase subunit beta |
|
| - UniProt
|
H0Y3Z3
H7BZ94
I3L0S0
I3L1Y5
I3L312
I3L398
I3L3P5
I3L3U6
I3L4M2
I3L514
I3NI03
P07237
|
| - NCBI
|
5034
|
| - KEGG metabolic
|
Protein processing in endoplasmic reticulum
|
|
13
|
RAB5B
|
ENSG00000111540
|
RAB5B, member RAS oncogene family |
|
| - UniProt
|
F8VPW9
F8VUA5
F8VVZ0
F8VWZ7
P61020
|
| - NCBI
|
5869
|
| - KEGG signaling
|
Ras signaling pathway
|
| - KEGG metabolic
|
Phagosome
Endocytosis
|
|
24
|
PPA2
|
ENSG00000138777
|
inorganic pyrophosphatase 2 |
|
| - UniProt
|
A0A0C4DGB9
D6R967
D6RAD3
D6RGI1
D6RGV9
F8W7R6
H0Y8X2
H0Y9D8
H0YAK2
Q9H2U2
|
| - NCBI
|
27068
|
| - KEGG metabolic
|
Oxidative phosphorylation
|
|
29
|
OAT
|
ENSG00000065154
|
ornithine aminotransferase |
|
| - UniProt
|
P04181
|
| - NCBI
|
4942
|
| - KEGG metabolic
|
Arginine and proline metabolism
|
|
23
|
IDH3A
|
ENSG00000166411
|
isocitrate dehydrogenase (NAD(+)) 3 catalytic subunit alpha |
|
| - UniProt
|
A0A0G2JL95
H0YKD0
H0YL05
H0YL72
H0YLF8
H0YLI6
H0YM46
H0YM64
H0YMU3
H0YMY5
H0YNF5
H0YNF8
P50213
Q68D72
|
| - NCBI
|
3419
|
| - KEGG metabolic
|
Citrate cycle (TCA cycle)
Biosynthesis of amino acids
Carbon metabolism
2-Oxocarboxylic acid metabolism
|
|
29
|
SHMT2
|
ENSG00000182199
|
serine hydroxymethyltransferase 2 |
|
| - UniProt
|
G3V241
G3V2D2
G3V2E4
G3V2W0
G3V2Y1
G3V2Y4
G3V3C6
G3V3Y8
G3V4T0
G3V4W5
G3V4X0
G3V540
G3V5L0
H0YIZ0
P34897
|
| - NCBI
|
6472
|
| - KEGG metabolic
|
Glycine, serine and threonine metabolism
One carbon pool by folate
Biosynthesis of amino acids
Carbon metabolism
Glyoxylate and dicarboxylate metabolism
|
|
25
|
HMGCL
|
ENSG00000117305
|
3-hydroxy-3-methylglutaryl-CoA lyase |
|
| - UniProt
|
H0Y2L7
P35914
|
| - NCBI
|
3155
|
| - KEGG metabolic
|
Peroxisome
Synthesis and degradation of ketone bodies
Valine, leucine and isoleucine degradation
Butanoate metabolism
|
|
27
|
PFKL
|
ENSG00000141959
|
phosphofructokinase, liver type |
|
| - UniProt
|
F8WEU2
P17858
|
| - NCBI
|
5211
|
| - KEGG signaling
|
Thyroid hormone signaling pathway
HIF-1 signaling pathway
AMPK signaling pathway
Glucagon signaling pathway
|
| - KEGG metabolic
|
RNA degradation
Pentose phosphate pathway
Galactose metabolism
Fructose and mannose metabolism
Glycolysis / Gluconeogenesis
Biosynthesis of amino acids
Carbon metabolism
|
|
20
|
UGP2
|
ENSG00000169764
|
UDP-glucose pyrophosphorylase 2 |
|
| - UniProt
|
A0A087WYS1
C9J3M0
C9J6Q0
C9JNZ1
C9JQU9
C9JTZ5
C9JUW1
C9JVG3
C9JWG0
E7EUC7
F2Z3H1
F2Z3P4
F8WC70
F8WDA2
H7C500
Q16851
|
| - NCBI
|
7360
|
| - KEGG metabolic
|
Starch and sucrose metabolism
Galactose metabolism
Pentose and glucuronate interconversions
Amino sugar and nucleotide sugar metabolism
|
|
25
|
ALDH1B1
|
ENSG00000137124
|
aldehyde dehydrogenase 1 family member B1 |
|
| - UniProt
|
A0A0U1RQK9
P30837
|
| - NCBI
|
219
|
| - KEGG metabolic
|
Pyruvate metabolism
Tryptophan metabolism
Fatty acid degradation
Valine, leucine and isoleucine degradation
Histidine metabolism
Glycolysis / Gluconeogenesis
Ascorbate and aldarate metabolism
Arginine and proline metabolism
Glycerolipid metabolism
beta-Alanine metabolism
Lysine degradation
|
|
29
|
ACO2
|
ENSG00000100412
|
aconitase 2 |
|
| - UniProt
|
A2A274
Q99798
|
| - NCBI
|
50
|
| - KEGG metabolic
|
Biosynthesis of amino acids
Citrate cycle (TCA cycle)
Carbon metabolism
2-Oxocarboxylic acid metabolism
Glyoxylate and dicarboxylate metabolism
|
|
22
|
IDH3G
|
ENSG00000067829
|
isocitrate dehydrogenase (NAD(+)) 3 non-catalytic subunit gamma |
|
| - UniProt
|
E7EQB8
E9PF84
G5E9Q7
H0Y5Q7
H7C1W2
P51553
|
| - NCBI
|
3421
|
| - KEGG metabolic
|
Citrate cycle (TCA cycle)
Biosynthesis of amino acids
Carbon metabolism
2-Oxocarboxylic acid metabolism
|
Copied subnetwork genes to clipboard
- Use as query
- Add to current query