Found 1 of 1 query genes

Network information:

Filter Results:

Evidence Source:
Filter by Tissue:

Select multiple tissues by holding down shift or ctrl.
Filter by Pathway:

Network appearance:

Label Type:
Node Size:
Charge:
Link distance:
Min confidence:

Query interactions

Interaction partners
Confidence
Network
MEX
PIN
SCL
PHP
MIR
TFB
PEX
GIN
DOM
QMS
GRG
Evidence types
HSA
MMU
RNO
CFA
GGA
DRE
CIN
DME
CEL
BTA
SCE
ATH
SPO
BSU
ECO
PFA
DDI
SSO
SSC
MJA
OSA
Species
In Gold st.

ID Query gene
ID Query ortholog

Log-likelihood ratio (LLR)
	Highly positive
	Positive
	Zero
	Negative
	Highly negative
Known coupling
	This network
	Other network

2. ENSG00000170458
3. CD14 molecule
- 2. LYN
  3. LYN proto-oncogene, Src…
  4. 1.000
  5. PPI
- 2. TLR4
  3. toll like receptor 4
  4. 1.000
  5. PPI
- 2. TLR2
  3. toll like receptor 2
  4. 1.000
  5. PPI
- 2. CD33
  3. CD33 molecule
  4. 1.000
  5. PPI
- 2. FCGR2A
  3. Fc fragment of IgG rece…
  4. 0.999
  5. PPI
- 2. FCGR3A
  3. Fc fragment of IgG rece…
  4. 0.999
  5. PPI
- 2. FCGR1A
  3. Fc fragment of IgG rece…
  4. 0.999
  5. PPI
- 2. TNFRSF1B
  3. TNF receptor superfamil…
  4. 0.999
  5. PPI
- 2. CD36
  3. CD36 molecule
  4. 0.990
  5. PPI
- 2. HLA-DRB1
  3. major histocompatibilit…
  4. 0.989
  5. PPI
- 2. CD81
  3. CD81 molecule
  4. 0.986
  5. PPI
- 2. LBP
  3. lipopolysaccharide bind…
  4. 0.974
  5. PPI
- 2. FCER1G
  3. Fc fragment of IgE rece…
  4. 0.971
  5. Complex
- 2. ITGB2
  3. integrin subunit beta 2
  4. 0.962
  5. Metabolic
- 2. HLA-DRB5
  3. major histocompatibilit…
  4. 0.942
  5. Metabolic
- 2. FOLR2
  3. folate receptor beta
  4. 0.933
  5. PPI
- 2. CYBB
  3. cytochrome b-245 beta c…
  4. 0.927
  5. Metabolic
- 2. CYBA
  3. cytochrome b-245 alpha …
  4. 0.922
  5. Metabolic
- 2. CD55
  3. CD55 molecule (Cromer b…
  4. 0.920
  5. PPI
- 2. CORO1A
  3. coronin 1A
  4. 0.913
  5. Metabolic
- 2. CD68
  3. CD68 molecule
  4. 0.902
  5. PPI
- 2. MNDA
  3. myeloid cell nuclear di…
  4. 0.898
  5. Metabolic
- 2. CD47
  3. CD47 molecule
  4. 0.888
  5. PPI
- 2. TYROBP
  3. transmembrane immune si…
  4. 0.884
  5. Complex
- 2. HLA-B
  3. major histocompatibilit…
  4. 0.881
  5. Metabolic
- 2. IRAK3
  3. interleukin 1 receptor …
  4. 0.877
  5. PPI
- 2. RHOG
  3. ras homolog family memb…
  4. 0.872
  5. Metabolic
- 2. ITGAX
  3. integrin subunit alpha X
  4. 0.857
  5. Metabolic
- 2. FGR
  3. FGR proto-oncogene, Src…
  4. 0.854
  5. Metabolic
- 2. CTSB
  3. cathepsin B
  4. 0.844
  5. Complex

Subnetwork gene interactions

ENSG00000170458

CD14 molecule

FunCoup

Use as query
Use pair as query
Add to current query

Ensembl

ENSG00000170458

UniProt

NCBI

CD81

CD81 molecule

FunCoup

Use as query
Use pair as query
Add to current query

Ensembl

ENSG00000110651

UniProt

NCBI

CORO1A

coronin 1A

FunCoup

Use as query
Use pair as query
Add to current query

Ensembl

ENSG00000102879

UniProt

NCBI

11151

ITGAX

integrin subunit alpha X

FunCoup

Use as query
Use pair as query
Add to current query

Ensembl

ENSG00000140678

UniProt

NCBI

3687

HLA-DRB1

major histocompatibility complex, class II, DR beta 1

FunCoup

Use as query
Use pair as query
Add to current query

Ensembl

ENSG00000196126

UniProt

P01911

NCBI

3123

CD33

CD33 molecule

FunCoup

Use as query
Use pair as query
Add to current query

Ensembl

ENSG00000105383

UniProt

NCBI

RHOG

ras homolog family member G

FunCoup

Use as query
Use pair as query
Add to current query

Ensembl

ENSG00000177105

UniProt

P84095

NCBI

TLR2

toll like receptor 2

FunCoup

Use as query
Use pair as query
Add to current query

Ensembl

ENSG00000137462

UniProt

NCBI

7097

TNFRSF1B

TNF receptor superfamily member 1B

FunCoup

Use as query
Use pair as query
Add to current query

Ensembl

ENSG00000028137

UniProt

NCBI

7133

CTSB

cathepsin B

FunCoup

Use as query
Use pair as query
Add to current query

Ensembl

ENSG00000164733

UniProt

NCBI

1508

TYROBP

transmembrane immune signaling adaptor TYROBP

FunCoup

Use as query
Use pair as query
Add to current query

Ensembl

ENSG00000011600

UniProt

NCBI

7305

ITGB2

integrin subunit beta 2

FunCoup

Use as query
Use pair as query
Add to current query

Ensembl

ENSG00000160255

UniProt

NCBI

3689

FCER1G

Fc fragment of IgE receptor Ig

FunCoup

Use as query
Use pair as query
Add to current query

Ensembl

ENSG00000158869

UniProt

NCBI

2207

MNDA

myeloid cell nuclear differentiation antigen

FunCoup

Use as query
Use pair as query
Add to current query

Ensembl

ENSG00000163563

UniProt

NCBI

4332

CYBA

cytochrome b-245 alpha chain

FunCoup

Use as query
Use pair as query
Add to current query

Ensembl

ENSG00000051523

UniProt

NCBI

1535

HLA-DRB5

major histocompatibility complex, class II, DR beta 5

FunCoup

Use as query
Use pair as query
Add to current query

Ensembl

ENSG00000198502

UniProt

Q30154

NCBI

3127

LYN

LYN proto-oncogene, Src family tyrosine kinase

FunCoup

Use as query
Use pair as query
Add to current query

Ensembl

ENSG00000254087

UniProt

NCBI

4067

CYBB

cytochrome b-245 beta chain

FunCoup

Use as query
Use pair as query
Add to current query

Ensembl

ENSG00000165168

UniProt

P04839

NCBI

1536

CD68

CD68 molecule

FunCoup

Use as query
Use pair as query
Add to current query

Ensembl

ENSG00000129226

UniProt

NCBI

TLR4

toll like receptor 4

FunCoup

Use as query
Use pair as query
Add to current query

Ensembl

ENSG00000136869

UniProt

NCBI

7099

CD36

CD36 molecule

FunCoup

Use as query
Use pair as query
Add to current query

Ensembl

ENSG00000135218

UniProt

NCBI

HLA-B

major histocompatibility complex, class I, B

FunCoup

Use as query
Use pair as query
Add to current query

Ensembl

ENSG00000234745

UniProt

NCBI

3106

FCGR3A

Fc fragment of IgG receptor IIIa

FunCoup

Use as query
Use pair as query
Add to current query

Ensembl

ENSG00000203747

UniProt

NCBI

2214

FGR

FGR proto-oncogene, Src family tyrosine kinase

FunCoup

Use as query
Use pair as query
Add to current query

Ensembl

ENSG00000000938

UniProt

NCBI

2268

FOLR2

folate receptor beta

FunCoup

Use as query
Use pair as query
Add to current query

Ensembl

ENSG00000165457

UniProt

NCBI

2350

LBP

lipopolysaccharide binding protein

FunCoup

Use as query
Use pair as query
Add to current query

Ensembl

ENSG00000129988

UniProt

P18428

NCBI

3929

FCGR2A

Fc fragment of IgG receptor IIa

FunCoup

Use as query
Use pair as query
Add to current query

Ensembl

ENSG00000143226

UniProt

NCBI

2212

CD47

CD47 molecule

FunCoup

Use as query
Use pair as query
Add to current query

Ensembl

ENSG00000196776

UniProt

NCBI

FCGR1A

Fc fragment of IgG receptor Ia

FunCoup

Use as query
Use pair as query
Add to current query

Ensembl

ENSG00000150337

UniProt

NCBI

2209

CD55

CD55 molecule (Cromer blood group)

FunCoup

Use as query
Use pair as query
Add to current query

Ensembl

ENSG00000196352

UniProt

NCBI

1604

IRAK3

interleukin 1 receptor associated kinase 3

FunCoup

Use as query
Use pair as query
Add to current query

Ensembl

ENSG00000090376

UniProt

NCBI

11213

Query genes

		Identifier	Description
30	ENSG00000170458	ENSG00000170458	CD14 molecule
		UniProt	D6RD81 D6RFL4 E7EVL5 P08571
		NCBI	929
		KEGG signaling	Toll-like receptor signaling pathway Hematopoietic cell lineage MAPK signaling pathway NF-kappa B signaling pathway
		KEGG metabolic	Phagosome

Subnetwork genes

		Identifier	Description
4	CD81	ENSG00000110651	CD81 molecule
		UniProt	A6NMH8 E9PIF1 E9PJK1 E9PM31 E9PPF5 E9PQV4 E9PRJ8 H0YDJ9 H0YDL9 H0YEE2 P60033
		NCBI	975
		KEGG signaling	B cell receptor signaling pathway
22	CORO1A	ENSG00000102879	coronin 1A
		UniProt	H3BNA2 H3BRJ0 H3BRY3 H3BSL1 H3BTU6 H3BU76 P31146
		NCBI	11151
		KEGG metabolic	Phagosome
13	ITGAX	ENSG00000140678	integrin subunit alpha X
		UniProt	A0A087X131 H3BN02 P20702
		NCBI	3687
		KEGG signaling	Complement and coagulation cascades
18	HLA-DRB1	ENSG00000196126	major histocompatibility complex, class II, DR beta 1
		UniProt	P01911
		NCBI	3123
11	CD33	ENSG00000105383	CD33 molecule
		UniProt	B4DF51 P20138
		NCBI	945
		KEGG signaling	Hematopoietic cell lineage
17	RHOG	ENSG00000177105	ras homolog family member G
		UniProt	P84095
		NCBI	391
16	TLR2	ENSG00000137462	toll like receptor 2
		UniProt	A0A0S2Z4L7 A0A2R8Y4N9 A0A2R8Y7R7 A0A2R8YHF6 O60603
		NCBI	7097
		KEGG signaling	Toll-like receptor signaling pathway PI3K-Akt signaling pathway
		KEGG metabolic	Phagosome
5	TNFRSF1B	ENSG00000028137	TNF receptor superfamily member 1B
		UniProt	B5A977 P20333
		NCBI	7133
		KEGG signaling	Adipocytokine signaling pathway Viral protein interaction with cytokine and cytokine receptor Cytokine-cytokine receptor interaction TNF signaling pathway
16	CTSB	ENSG00000164733	cathepsin B
		UniProt	E9PCB3 E9PHZ5 E9PID0 E9PIS1 E9PJ67 E9PKQ7 E9PKX0 E9PL32 E9PLY3 E9PNL5 E9PQM1 E9PR00 E9PR54 E9PS78 E9PSG5 P07858 R4GMQ5
		NCBI	1508
		KEGG signaling	Antigen processing and presentation NOD-like receptor signaling pathway Apoptosis
		KEGG metabolic	Lysosome Autophagy - animal
19	TYROBP	ENSG00000011600	transmembrane immune signaling adaptor TYROBP
		UniProt	K7EKK0 K7ES93 O43914 X6RGC9
		NCBI	7305
		KEGG signaling	Natural killer cell mediated cytotoxicity
20	ITGB2	ENSG00000160255	integrin subunit beta 2
		UniProt	A0A494C0X7 A8MVG7 D3DSM0 E5RFI0 E5RGK9 E5RHE6 E5RHT0 E5RIE4 E5RIG7 E5RK25 E5RK54 E7EVZ9 J3KNI6 P05107
		NCBI	3689
		KEGG signaling	Complement and coagulation cascades Rap1 signaling pathway Natural killer cell mediated cytotoxicity Leukocyte transendothelial migration Hippo signaling pathway Cell adhesion molecules (CAMs)
		KEGG metabolic	Phagosome
23	FCER1G	ENSG00000158869	Fc fragment of IgE receptor Ig
		UniProt	A6NCQ8 P30273
		NCBI	2207
		KEGG signaling	Fc epsilon RI signaling pathway Natural killer cell mediated cytotoxicity Phospholipase D signaling pathway Sphingolipid signaling pathway C-type lectin receptor signaling pathway
13	MNDA	ENSG00000163563	myeloid cell nuclear differentiation antigen
		UniProt	H0Y6P3 P41218
		NCBI	4332
19	CYBA	ENSG00000051523	cytochrome b-245 alpha chain
		UniProt	H3BNP7 H3BPX1 H3BPZ7 H3BR52 H3BT77 P13498
		NCBI	1535
		KEGG signaling	NOD-like receptor signaling pathway Leukocyte transendothelial migration
		KEGG metabolic	Phagosome
13	HLA-DRB5	ENSG00000198502	major histocompatibility complex, class II, DR beta 5
		UniProt	Q30154
		NCBI	3127
		KEGG signaling	Antigen processing and presentation Hematopoietic cell lineage Intestinal immune network for IgA production Cell adhesion molecules (CAMs)
		KEGG metabolic	Phagosome
19	LYN	ENSG00000254087	LYN proto-oncogene, Src family tyrosine kinase
		UniProt	E5RJ37 P07948
		NCBI	4067
		KEGG signaling	Fc gamma R-mediated phagocytosis Long-term depression Fc epsilon RI signaling pathway B cell receptor signaling pathway NF-kappa B signaling pathway Chemokine signaling pathway
20	CYBB	ENSG00000165168	cytochrome b-245 beta chain
		UniProt	P04839
		NCBI	1536
		KEGG signaling	NOD-like receptor signaling pathway HIF-1 signaling pathway Leukocyte transendothelial migration
		KEGG metabolic	Phagosome
18	CD68	ENSG00000129226	CD68 molecule
		UniProt	J3KRX0 J3KT24 P34810
		NCBI	968
		KEGG metabolic	Lysosome
8	TLR4	ENSG00000136869	toll like receptor 4
		UniProt	A0A2R8Y7P4 O00206
		NCBI	7099
		KEGG signaling	NOD-like receptor signaling pathway Toll-like receptor signaling pathway HIF-1 signaling pathway NF-kappa B signaling pathway PI3K-Akt signaling pathway
		KEGG metabolic	Phagosome
5	CD36	ENSG00000135218	CD36 molecule
		UniProt	E7ERZ9 E7EU05 E7EVU1 E7EWI4 E7EX47 E9PC45 E9PJX8 E9PLT1 H0YEE7 P16671
		NCBI	948
		KEGG signaling	Adipocytokine signaling pathway ECM-receptor interaction Hematopoietic cell lineage AMPK signaling pathway PPAR signaling pathway
		KEGG metabolic	Fat digestion and absorption Phagosome
16	HLA-B	ENSG00000234745	major histocompatibility complex, class I, B
		UniProt	A0A1W2PP29 A0A1W2PPR8 A0A1W2PQE2 F6U0H7 P01889
		NCBI	3106
		KEGG signaling	Antigen processing and presentation Natural killer cell mediated cytotoxicity Cell adhesion molecules (CAMs)
		KEGG metabolic	Phagosome Endocytosis
3	FCGR3A	ENSG00000203747	Fc fragment of IgG receptor IIIa
		UniProt	C9JC71 H0Y755 M9MML0 P08637
		NCBI	2214
		KEGG signaling	Fc gamma R-mediated phagocytosis Natural killer cell mediated cytotoxicity
		KEGG metabolic	Phagosome
12	FGR	ENSG00000000938	FGR proto-oncogene, Src family tyrosine kinase
		UniProt	P09769 Q5TGY6
		NCBI	2268
		KEGG signaling	Chemokine signaling pathway
3	FOLR2	ENSG00000165457	folate receptor beta
		UniProt	A0A087WWY2 E7EU04 F5GXV3 F5GZ45 F5H3Z4 F5H4Z6 F5H5L8 J3KQP4 J3KR13 P14207
		NCBI	2350
		KEGG metabolic	Endocytosis
1	LBP	ENSG00000129988	lipopolysaccharide binding protein
		UniProt	P18428
		NCBI	3929
		KEGG signaling	Toll-like receptor signaling pathway NF-kappa B signaling pathway
11	FCGR2A	ENSG00000143226	Fc fragment of IgG receptor IIa
		UniProt	F5GX41 F5GXY9 P12318 V9GY55 V9GY83
		NCBI	2212
		KEGG signaling	Fc gamma R-mediated phagocytosis
		KEGG metabolic	Phagosome
1	CD47	ENSG00000196776	CD47 molecule
		UniProt	A0A2R8Y484 H0YC40 H7BYS8 Q08722
		NCBI	961
		KEGG signaling	ECM-receptor interaction
4	FCGR1A	ENSG00000150337	Fc fragment of IgG receptor Ia
		UniProt	C9JSN8 P12314
		NCBI	2209
		KEGG signaling	Fc gamma R-mediated phagocytosis Hematopoietic cell lineage
		KEGG metabolic	Phagosome
1	CD55	ENSG00000196352	CD55 molecule (Cromer blood group)
		UniProt	A0A2R8Y4B4 A0A2R8YDY3 A0A2R8YEC5 B1AP13 B1AP15 H3BLV0 H7BY55 P08174
		NCBI	1604
		KEGG signaling	Complement and coagulation cascades Hematopoietic cell lineage
1	IRAK3	ENSG00000090376	interleukin 1 receptor associated kinase 3
		UniProt	F5GYN6 Q9Y616
		NCBI	11213
		KEGG signaling	Neurotrophin signaling pathway

Enrichment analysis

Search for enrichment of pathways or functional gene sets for your subnetwork genes

To use PathwAX, first use the button below to copy the subnetwork genes and then paste them in PathwAX

Copied subnetwork genes to clipboard

Use as query
Add to current query

	jSquid_subnetworks.xml	238.93 KB
	H.sapiens_subnetwork.tsv	28.69 KB

Species:

Network information:

Filter Results:

Network appearance:

ENSG00000170458

CD81

CORO1A

ITGAX

HLA-DRB1

CD33

RHOG

TLR2

TNFRSF1B

CTSB

TYROBP

ITGB2

FCER1G

MNDA

CYBA

HLA-DRB5

LYN

CYBB

CD68

TLR4

CD36

HLA-B

FCGR3A

FGR

FOLR2

LBP

FCGR2A

CD47

FCGR1A

CD55

IRAK3

JavaScript is required.