Found 1 of 1 query genes

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Query interactions

Interaction partners
Confidence
Network
MEX
PIN
SCL
PHP
MIR
TFB
PEX
GIN
DOM
QMS
GRG
Evidence types
HSA
MMU
RNO
CFA
GGA
DRE
CIN
DME
CEL
BTA
SCE
ATH
SPO
BSU
ECO
PFA
DDI
SSO
SSC
MJA
OSA
Species
In Gold st.

ID Query gene
ID Query ortholog

Log-likelihood ratio (LLR)
	Highly positive
	Positive
	Zero
	Negative
	Highly negative
Known coupling
	This network
	Other network

2. ENSG00000163344
3. phosphomevalonate kinase
- 2. PITPNA
  3. phosphatidylinositol tr…
  4. 1.000
  5. PPI
- 2. SSB
  3. small RNA binding exonu…
  4. 0.987
  5. PPI
- 2. SOD1
  3. superoxide dismutase 1
  4. 0.981
  5. Metabolic
- 2. FASN
  3. fatty acid synthase
  4. 0.980
  5. Metabolic
- 2. PGLS
  3. 6-phosphogluconolactona…
  4. 0.979
  5. Metabolic
- 2. HINT1
  3. histidine triad nucleot…
  4. 0.978
  5. Metabolic
- 2. ADH5
  3. alcohol dehydrogenase 5…
  4. 0.972
  5. Metabolic
- 2. MPDU1
  3. mannose-P-dolichol util…
  4. 0.962
  5. PPI
- 2. MLF2
  3. myeloid leukemia factor…
  4. 0.961
  5. PPI
- 2. P4HB
  3. prolyl 4-hydroxylase su…
  4. 0.953
  5. Metabolic
- 2. MIF
  3. macrophage migration in…
  4. 0.952
  5. Metabolic
- 2. SDHA
  3. succinate dehydrogenase…
  4. 0.948
  5. PPI
- 2. PSMB2
  3. proteasome 20S subunit …
  4. 0.945
  5. Metabolic
- 2. PPIB
  3. peptidylprolyl isomeras…
  4. 0.942
  5. Metabolic
- 2. PCNA
  3. proliferating cell nucl…
  4. 0.933
  5. Metabolic
- 2. PRDX1
  3. peroxiredoxin 1
  4. 0.931
  5. Metabolic
- 2. PRDX2
  3. peroxiredoxin 2
  4. 0.917
  5. Metabolic
- 2. SLC25A1
  3. solute carrier family 2…
  4. 0.914
  5. Metabolic
- 2. PARK7
  3. Parkinsonism associated…
  4. 0.913
  5. Metabolic
- 2. LMAN2
  3. lectin, mannose binding…
  4. 0.911
  5. Metabolic
- 2. NEDD8
  3. NEDD8 ubiquitin like mo…
  4. 0.911
  5. Metabolic
- 2. TUFM
  3. Tu translation elongati…
  4. 0.909
  5. Metabolic
- 2. RAN
  3. RAN, member RAS oncogen…
  4. 0.908
  5. Metabolic
- 2. DBI
  3. diazepam binding inhibi…
  4. 0.907
  5. Metabolic
- 2. PFN1
  3. profilin 1
  4. 0.907
  5. Metabolic
- 2. BLVRB
  3. biliverdin reductase B
  4. 0.903
  5. Metabolic
- 2. PDCD10
  3. programmed cell death 10
  4. 0.896
  5. Metabolic
- 2. GARS1
  3. glycyl-tRNA synthetase 1
  4. 0.894
  5. Metabolic
- 2. MBD5
  3. methyl-CpG binding doma…
  4. 0.894
  5. PPI
- 2. SSBP1
  3. single stranded DNA bin…
  4. 0.893
  5. Metabolic

Subnetwork gene interactions

ENSG00000163344

phosphomevalonate kinase

FunCoup

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Ensembl

ENSG00000163344

UniProt

Q15126

NCBI

10654

PRDX2

peroxiredoxin 2

FunCoup

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Ensembl

ENSG00000167815

UniProt

NCBI

7001

PARK7

Parkinsonism associated deglycase

FunCoup

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Ensembl

ENSG00000116288

UniProt

NCBI

11315

PRDX1

peroxiredoxin 1

FunCoup

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Ensembl

ENSG00000117450

UniProt

NCBI

5052

LMAN2

lectin, mannose binding 2

FunCoup

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Ensembl

ENSG00000169223

UniProt

NCBI

10960

PSMB2

proteasome 20S subunit beta 2

FunCoup

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Ensembl

ENSG00000126067

UniProt

NCBI

5690

SLC25A1

solute carrier family 25 member 1

FunCoup

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Ensembl

ENSG00000100075

UniProt

NCBI

6576

HINT1

histidine triad nucleotide binding protein 1

FunCoup

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Ensembl

ENSG00000169567

UniProt

NCBI

3094

MPDU1

mannose-P-dolichol utilization defect 1

FunCoup

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Ensembl

ENSG00000129255

UniProt

NCBI

9526

BLVRB

biliverdin reductase B

FunCoup

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Ensembl

ENSG00000090013

UniProt

NCBI

PITPNA

phosphatidylinositol transfer protein alpha

FunCoup

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Ensembl

ENSG00000174238

UniProt

NCBI

5306

PGLS

6-phosphogluconolactonase

FunCoup

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Ensembl

ENSG00000130313

UniProt

NCBI

25796

P4HB

prolyl 4-hydroxylase subunit beta

FunCoup

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Ensembl

ENSG00000185624

UniProt

NCBI

5034

PDCD10

programmed cell death 10

FunCoup

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Ensembl

ENSG00000114209

UniProt

NCBI

11235

TUFM

Tu translation elongation factor, mitochondrial

FunCoup

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Ensembl

ENSG00000178952

UniProt

NCBI

7284

GARS1

glycyl-tRNA synthetase 1

FunCoup

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Ensembl

ENSG00000106105

UniProt

NCBI

2617

NEDD8

NEDD8 ubiquitin like modifier

FunCoup

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Ensembl

ENSG00000129559

UniProt

NCBI

4738

SSBP1

single stranded DNA binding protein 1

FunCoup

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Ensembl

ENSG00000106028

UniProt

NCBI

6742

PFN1

profilin 1

FunCoup

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Ensembl

ENSG00000108518

UniProt

NCBI

5216

MIF

macrophage migration inhibitory factor

FunCoup

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Ensembl

ENSG00000240972

UniProt

P14174

NCBI

4282

ADH5

alcohol dehydrogenase 5 (class III), chi polypeptide

FunCoup

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Ensembl

ENSG00000197894

UniProt

NCBI

DBI

diazepam binding inhibitor, acyl-CoA binding protein

FunCoup

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Ensembl

ENSG00000155368

UniProt

NCBI

1622

PCNA

proliferating cell nuclear antigen

FunCoup

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Ensembl

ENSG00000132646

UniProt

P12004

NCBI

5111

SOD1

superoxide dismutase 1

FunCoup

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Ensembl

ENSG00000142168

UniProt

NCBI

6647

SDHA

succinate dehydrogenase complex flavoprotein subunit A

FunCoup

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Ensembl

ENSG00000073578

UniProt

NCBI

6389

RAN

RAN, member RAS oncogene family

FunCoup

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Ensembl

ENSG00000132341

UniProt

NCBI

5901

FASN

fatty acid synthase

FunCoup

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Ensembl

ENSG00000169710

UniProt

NCBI

2194

PPIB

peptidylprolyl isomerase B

FunCoup

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Ensembl

ENSG00000166794

UniProt

P23284

NCBI

5479

SSB

small RNA binding exonuclease protection factor La

FunCoup

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Ensembl

ENSG00000138385

UniProt

NCBI

6741

MLF2

myeloid leukemia factor 2

FunCoup

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Ensembl

ENSG00000089693

UniProt

NCBI

8079

MBD5

methyl-CpG binding domain protein 5

FunCoup

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Ensembl

ENSG00000204406

UniProt

NCBI

55777

Query genes

		Identifier	Description
30	ENSG00000163344	ENSG00000163344	phosphomevalonate kinase
		UniProt	Q15126
		NCBI	10654
		KEGG metabolic	Terpenoid backbone biosynthesis Peroxisome

Subnetwork genes

		Identifier	Description
26	PRDX2	ENSG00000167815	peroxiredoxin 2
		UniProt	A6NIW5 P32119
		NCBI	7001
27	PARK7	ENSG00000116288	Parkinsonism associated deglycase
		UniProt	K7ELW0 K7EN27 Q99497
		NCBI	11315
28	PRDX1	ENSG00000117450	peroxiredoxin 1
		UniProt	A0A0A0MRQ5 A0A0A0MSI0 Q06830
		NCBI	5052
		KEGG metabolic	Peroxisome
28	LMAN2	ENSG00000169223	lectin, mannose binding 2
		UniProt	D6RBH1 D6RBV2 D6RDX1 D6RIU4 Q12907
		NCBI	10960
		KEGG metabolic	Protein processing in endoplasmic reticulum
28	PSMB2	ENSG00000126067	proteasome 20S subunit beta 2
		UniProt	A0A087WVV1 P49721
		NCBI	5690
		KEGG metabolic	Proteasome
28	SLC25A1	ENSG00000100075	solute carrier family 25 member 1
		UniProt	B4DP62 P53007
		NCBI	6576
28	HINT1	ENSG00000169567	histidine triad nucleotide binding protein 1
		UniProt	D6RC06 D6RD60 D6RE99 D6REP8 H0YC49 P49773
		NCBI	3094
12	MPDU1	ENSG00000129255	mannose-P-dolichol utilization defect 1
		UniProt	I3L1D2 I3L261 I3L295 I3L405 I3L4E0 I3L4T1 J3KSI4 J3KT75 J3KTK8 J3QQZ4 J3QRD5 J3QS48 J3QW43 O75352
		NCBI	9526
26	BLVRB	ENSG00000090013	biliverdin reductase B
		UniProt	A0A2R8Y7Y9 A0A2R8YEP4 M0QZL1 M0R192 P30043
		NCBI	645
		KEGG metabolic	Riboflavin metabolism Porphyrin and chlorophyll metabolism
25	PITPNA	ENSG00000174238	phosphatidylinositol transfer protein alpha
		UniProt	F5GWE5 I3L2X8 I3L3W1 I3L459 I3L471 I3L4C0 I3L4H1 I3L4U7 I3NI10 Q00169
		NCBI	5306
27	PGLS	ENSG00000130313	6-phosphogluconolactonase
		UniProt	M0R0U3 M0R1L2 M0R261 O95336
		NCBI	25796
		KEGG metabolic	Pentose phosphate pathway Carbon metabolism
28	P4HB	ENSG00000185624	prolyl 4-hydroxylase subunit beta
		UniProt	H0Y3Z3 H7BZ94 I3L0S0 I3L1Y5 I3L312 I3L398 I3L3P5 I3L3U6 I3L4M2 I3L514 I3NI03 P07237
		NCBI	5034
		KEGG metabolic	Protein processing in endoplasmic reticulum
26	PDCD10	ENSG00000114209	programmed cell death 10
		UniProt	C9J363 C9J5C3 C9J6F3 C9J932 C9JND6 C9JSA3 F8WDF3 H7C5M9 Q9BUL8
		NCBI	11235
28	TUFM	ENSG00000178952	Tu translation elongation factor, mitochondrial
		UniProt	H3BNU3 P49411
		NCBI	7284
27	GARS1	ENSG00000106105	glycyl-tRNA synthetase 1
		UniProt	F8WCK4 H7C443 P41250
		NCBI	2617
		KEGG metabolic	Aminoacyl-tRNA biosynthesis
26	NEDD8	ENSG00000129559	NEDD8 ubiquitin like modifier
		UniProt	F8VSA6 Q15843
		NCBI	4738
26	SSBP1	ENSG00000106028	single stranded DNA binding protein 1
		UniProt	C9J8J0 C9K0U8 E7EUY5 Q04837
		NCBI	6742
		KEGG metabolic	DNA replication Homologous recombination Mismatch repair
25	PFN1	ENSG00000108518	profilin 1
		UniProt	I3L3D5 K7EJ44 P07737
		NCBI	5216
		KEGG signaling	Rap1 signaling pathway
27	MIF	ENSG00000240972	macrophage migration inhibitory factor
		UniProt	P14174
		NCBI	4282
		KEGG metabolic	Phenylalanine metabolism Tyrosine metabolism
27	ADH5	ENSG00000197894	alcohol dehydrogenase 5 (class III), chi polypeptide
		UniProt	D6R9G2 D6RAY0 D6RFE4 H0YAG8 P11766
		NCBI	128
		KEGG metabolic	Retinol metabolism Fatty acid degradation Glycolysis / Gluconeogenesis Tyrosine metabolism Carbon metabolism Metabolism of xenobiotics by cytochrome P450 Drug metabolism - cytochrome P450
28	DBI	ENSG00000155368	diazepam binding inhibitor, acyl-CoA binding protein
		UniProt	A0A0A0MTI5 B8ZWD1 P07108
		NCBI	1622
		KEGG signaling	PPAR signaling pathway
28	PCNA	ENSG00000132646	proliferating cell nuclear antigen
		UniProt	P12004
		NCBI	5111
		KEGG signaling	Tight junction Cell cycle
		KEGG metabolic	DNA replication Mismatch repair Nucleotide excision repair Base excision repair
27	SOD1	ENSG00000142168	superoxide dismutase 1
		UniProt	H7BYH4 P00441
		NCBI	6647
		KEGG metabolic	Peroxisome
20	SDHA	ENSG00000073578	succinate dehydrogenase complex flavoprotein subunit A
		UniProt	A0A087X1I3 D6REB7 D6RFM5 H0Y8S2 H0Y8X1 P31040
		NCBI	6389
		KEGG metabolic	Oxidative phosphorylation Citrate cycle (TCA cycle) Carbon metabolism
28	RAN	ENSG00000132341	RAN, member RAS oncogene family
		UniProt	A0A087X0W0 B4DV51 B5MDF5 F5H018 H0YFC6 J3KQE5 P62826
		NCBI	5901
		KEGG metabolic	Ribosome biogenesis in eukaryotes RNA transport
25	FASN	ENSG00000169710	fatty acid synthase
		UniProt	A0A0U1RQF0 A0A0U1RRG3 A0A1B0GTR5 A0A1B0GVK4 A0A1B0GWG8 J3KTF0 P49327
		NCBI	2194
		KEGG signaling	AMPK signaling pathway Insulin signaling pathway
		KEGG metabolic	Fatty acid biosynthesis Fatty acid metabolism
27	PPIB	ENSG00000166794	peptidylprolyl isomerase B
		UniProt	P23284
		NCBI	5479
22	SSB	ENSG00000138385	small RNA binding exonuclease protection factor La
		UniProt	E7ERC4 E9PFL9 E9PGX9 P05455
		NCBI	6741
3	MLF2	ENSG00000089693	myeloid leukemia factor 2
		UniProt	F5H0Y3 F5H7L5 F5H800 Q15773
		NCBI	8079
1	MBD5	ENSG00000204406	methyl-CpG binding domain protein 5
		UniProt	A0A0D9SEP6 A0A0D9SF16 A0A0D9SG23 A0A1B0GUJ9 A0A1B0GW10 E9PHH0 H7C066 Q9P267
		NCBI	55777

Enrichment analysis

Search for enrichment of pathways or functional gene sets for your subnetwork genes

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	jSquid_subnetworks.xml	297.06 KB
	H.sapiens_subnetwork.tsv	70.78 KB

Species:

Network information:

Filter Results:

Network appearance:

ENSG00000163344

PRDX2

PARK7

PRDX1

LMAN2

PSMB2

SLC25A1

HINT1

MPDU1

BLVRB

PITPNA

PGLS

P4HB

PDCD10

TUFM

GARS1

NEDD8

SSBP1

PFN1

MIF

ADH5

DBI

PCNA

SOD1

SDHA

RAN

FASN

PPIB

SSB

MLF2

MBD5

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