Found 1 of 1 query genes

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Query interactions

Interaction partners
Confidence
Network
MEX
PIN
SCL
PHP
MIR
TFB
PEX
GIN
DOM
QMS
GRG
Evidence types
HSA
MMU
RNO
CFA
GGA
DRE
CIN
DME
CEL
BTA
SCE
ATH
SPO
BSU
ECO
PFA
DDI
SSO
SSC
MJA
OSA
Species
In Gold st.

ID Query gene
ID Query ortholog

Log-likelihood ratio (LLR)
	Highly positive
	Positive
	Zero
	Negative
	Highly negative
Known coupling
	This network
	Other network

2. ENSG00000149782
3. phospholipase C beta 3
- 2. EZR
  3. ezrin
  4. 0.972
  5. PPI
- 2. EFTUD2
  3. elongation factor Tu GT…
  4. 0.970
  5. PPI
- 2. PARD3
  3. par-3 family cell polar…
  4. 0.955
  5. PPI
- 2. SNTA1
  3. syntrophin alpha 1
  4. 0.910
  5. PPI
- 2. PTPN6
  3. protein tyrosine phosph…
  4. 0.721
  5. PPI
- 2. NEDD1
  3. NEDD1 gamma-tubulin rin…
  4. 0.673
  5. PPI
- 2. NEDD4
  3. NEDD4 E3 ubiquitin prot…
  4. 0.659
  5. Metabolic
- 2. SLC9A3R1
  3. SLC9A3 regulator 1
  4. 0.550
  5. PPI
- 2. SYNCRIP
  3. synaptotagmin binding c…
  4. 0.532
  5. PPI
- 2. KRIT1
  3. KRIT1 ankyrin repeat co…
  4. 0.494
  5. PPI
- 2. PSMC4
  3. proteasome 26S subunit,…
  4. 0.427
  5. Metabolic
- 2. PRKCB
  3. protein kinase C beta
  4. 0.415
  5. Metabolic
- 2. ABL1
  3. ABL proto-oncogene 1, n…
  4. 0.411
  5. Metabolic

Subnetwork gene interactions

ENSG00000149782

phospholipase C beta 3

FunCoup

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Ensembl

ENSG00000149782

UniProt

Q01970

NCBI

5331

ABL1

ABL proto-oncogene 1, non-receptor tyrosine kinase

FunCoup

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Ensembl

ENSG00000097007

UniProt

NCBI

PRKCB

protein kinase C beta

FunCoup

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Ensembl

ENSG00000166501

UniProt

NCBI

5579

PSMC4

proteasome 26S subunit, ATPase 4

FunCoup

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Ensembl

ENSG00000013275

UniProt

P43686

NCBI

5704

NEDD4

NEDD4 E3 ubiquitin protein ligase

FunCoup

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Ensembl

ENSG00000069869

UniProt

NCBI

4734

EZR

ezrin

FunCoup

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Ensembl

ENSG00000092820

UniProt

NCBI

7430

SLC9A3R1

SLC9A3 regulator 1

FunCoup

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Ensembl

ENSG00000109062

UniProt

NCBI

9368

PTPN6

protein tyrosine phosphatase non-receptor type 6

FunCoup

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Ensembl

ENSG00000111679

UniProt

NCBI

5777

EFTUD2

elongation factor Tu GTP binding domain containing 2

FunCoup

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Ensembl

ENSG00000108883

UniProt

NCBI

9343

PARD3

par-3 family cell polarity regulator

FunCoup

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Ensembl

ENSG00000148498

UniProt

NCBI

56288

KRIT1

KRIT1 ankyrin repeat containing

FunCoup

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Ensembl

ENSG00000001631

UniProt

NCBI

SYNCRIP

synaptotagmin binding cytoplasmic RNA interacting protein

FunCoup

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Ensembl

ENSG00000135316

UniProt

NCBI

10492

NEDD1

NEDD1 gamma-tubulin ring complex targeting factor

FunCoup

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Ensembl

ENSG00000139350

UniProt

NCBI

121441

SNTA1

syntrophin alpha 1

FunCoup

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Ensembl

ENSG00000101400

UniProt

Q13424

NCBI

6640

Query genes

		Identifier	Description
13	ENSG00000149782	ENSG00000149782	phospholipase C beta 3
		UniProt	Q01970
		NCBI	5331
		KEGG signaling	Thyroid hormone signaling pathway Calcium signaling pathway Adrenergic signaling in cardiomyocytes Chemokine signaling pathway Long-term potentiation NOD-like receptor signaling pathway Gap junction cGMP-PKG signaling pathway Relaxin signaling pathway Dopaminergic synapse Serotonergic synapse Cholinergic synapse Glutamatergic synapse Glucagon signaling pathway Retrograde endocannabinoid signaling Oxytocin signaling pathway Apelin signaling pathway Phospholipase D signaling pathway Vascular smooth muscle contraction Sphingolipid signaling pathway Phosphatidylinositol signaling system Long-term depression Rap1 signaling pathway Wnt signaling pathway Melanogenesis Estrogen signaling pathway GnRH signaling pathway
		KEGG metabolic	Carbohydrate digestion and absorption Inositol phosphate metabolism

Subnetwork genes

		Identifier	Description
1	ABL1	ENSG00000097007	ABL proto-oncogene 1, non-receptor tyrosine kinase
		UniProt	P00519 R4GRW0
		NCBI	25
		KEGG signaling	Neurotrophin signaling pathway Ras signaling pathway ErbB signaling pathway Cell cycle
2	PRKCB	ENSG00000166501	protein kinase C beta
		UniProt	H3BV73 I3L148 I3L1Z0 P05771
		NCBI	5579
		KEGG signaling	Thyroid hormone signaling pathway Calcium signaling pathway NF-kappa B signaling pathway Chemokine signaling pathway Fc gamma R-mediated phagocytosis Long-term potentiation B cell receptor signaling pathway Gap junction HIF-1 signaling pathway Dopaminergic synapse GABAergic synapse Serotonergic synapse Cholinergic synapse Glutamatergic synapse Oxytocin signaling pathway Retrograde endocannabinoid signaling Leukocyte transendothelial migration MAPK signaling pathway VEGF signaling pathway mTOR signaling pathway Vascular smooth muscle contraction Sphingolipid signaling pathway Phosphatidylinositol signaling system Rap1 signaling pathway Long-term depression Focal adhesion Ras signaling pathway Wnt signaling pathway ErbB signaling pathway Natural killer cell mediated cytotoxicity Melanogenesis GnRH signaling pathway
		KEGG metabolic	Carbohydrate digestion and absorption
2	PSMC4	ENSG00000013275	proteasome 26S subunit, ATPase 4
		UniProt	P43686
		NCBI	5704
		KEGG metabolic	Proteasome
2	NEDD4	ENSG00000069869	NEDD4 E3 ubiquitin protein ligase
		UniProt	A0A3B3IUC1 H0Y8H4 H0Y8X6 H0Y9L1 H0YA37 P46934
		NCBI	4734
		KEGG signaling	Tight junction
		KEGG metabolic	Endocytosis Ubiquitin mediated proteolysis
2	EZR	ENSG00000092820	ezrin
		UniProt	E7EQR4 P15311
		NCBI	7430
		KEGG signaling	Tight junction Leukocyte transendothelial migration
2	SLC9A3R1	ENSG00000109062	SLC9A3 regulator 1
		UniProt	J3QRA3 J3QRP6 O14745
		NCBI	9368
		KEGG signaling	Tight junction
1	PTPN6	ENSG00000111679	protein tyrosine phosphatase non-receptor type 6
		UniProt	F5GXD4 F5GY79 F5H0N8 F5H1V7 F5H1Z8 F5H4Z1 F5H5H9 P29350 U3KQS1
		NCBI	5777
		KEGG signaling	Adherens junction JAK-STAT signaling pathway B cell receptor signaling pathway Natural killer cell mediated cytotoxicity T cell receptor signaling pathway
3	EFTUD2	ENSG00000108883	elongation factor Tu GTP binding domain containing 2
		UniProt	K7EIT3 K7EIV5 K7EJ74 K7EP67 K7EQ26 K7ERJ5 Q15029
		NCBI	9343
		KEGG metabolic	Spliceosome
1	PARD3	ENSG00000148498	par-3 family cell polarity regulator
		UniProt	B1AP52 F5GZI3 Q5VWU8 Q5VWV2 Q8TEW0
		NCBI	56288
		KEGG signaling	Rap1 signaling pathway Adherens junction Tight junction Chemokine signaling pathway Hippo signaling pathway Neuroactive ligand-receptor interaction
		KEGG metabolic	Endocytosis
1	KRIT1	ENSG00000001631	KRIT1 ankyrin repeat containing
		UniProt	A0A0C4DG23 C9J3W7 C9J718 C9JBN7 C9JD43 C9JD81 C9JEW7 C9JF32 C9JI47 C9JIY2 C9JJM9 C9JSG7 C9JXI9 O00522
		NCBI	889
		KEGG signaling	Rap1 signaling pathway
2	SYNCRIP	ENSG00000135316	synaptotagmin binding cytoplasmic RNA interacting protein
		UniProt	B7Z645 F6UXX1 O60506
		NCBI	10492
1	NEDD1	ENSG00000139350	NEDD1 gamma-tubulin ring complex targeting factor
		UniProt	G3V2M9 G3V2S2 G3V2V3 G3V4I9 G3V4L2 Q8NHV4
		NCBI	121441
1	SNTA1	ENSG00000101400	syntrophin alpha 1
		UniProt	Q13424
		NCBI	6640

Enrichment analysis

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	jSquid_subnetworks.xml	126.55 KB
	H.sapiens_subnetwork.tsv	3.30 KB

Species:

Network information:

Filter Results:

Network appearance:

ENSG00000149782

ABL1

PRKCB

PSMC4

NEDD4

EZR

SLC9A3R1

PTPN6

EFTUD2

PARD3

KRIT1

SYNCRIP

NEDD1

SNTA1

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