Found 1 of 1 query genes

Network information:

Filter Results:

Evidence Source:
Filter by Tissue:

Select multiple tissues by holding down shift or ctrl.
Filter by Pathway:

Network appearance:

Label Type:
Node Size:
Charge:
Link distance:
Min confidence:

Query interactions

Interaction partners
Confidence
Network
MEX
PIN
SCL
PHP
MIR
TFB
PEX
GIN
DOM
QMS
GRG
Evidence types
HSA
MMU
RNO
CFA
GGA
DRE
CIN
DME
CEL
BTA
SCE
ATH
SPO
BSU
ECO
PFA
DDI
SSO
SSC
MJA
OSA
Species
In Gold st.

ID Query gene
ID Query ortholog

Log-likelihood ratio (LLR)
	Highly positive
	Positive
	Zero
	Negative
	Highly negative
Known coupling
	This network
	Other network

2. ENSG00000143839
3. renin
- 2. TMLHE
  3. trimethyllysine hydroxy…
  4. 0.976
  5. Metabolic
- 2. GYS1
  3. glycogen synthase 1
  4. 0.968
  5. Metabolic
- 2. CTSA
  3. cathepsin A
  4. 0.959
  5. Metabolic
- 2. GYS2
  3. glycogen synthase 2
  4. 0.948
  5. Metabolic
- 2. VCP
  3. valosin containing prot…
  4. 0.944
  5. Metabolic
- 2. DCPS
  3. decapping enzyme, scave…
  4. 0.918
  5. Metabolic
- 2. DHDH
  3. dihydrodiol dehydrogena…
  4. 0.900
  5. Metabolic
- 2. GRHPR
  3. glyoxylate and hydroxyp…
  4. 0.893
  5. Complex
- 2. AGL
  3. amylo-alpha-1, 6-glucos…
  4. 0.840
  5. Complex
- 2. BBOX1
  3. gamma-butyrobetaine hyd…
  4. 0.772
  5. Metabolic
- 2. SLC25A3
  3. solute carrier family 2…
  4. 0.767
  5. Metabolic
- 2. PRKAR2A
  3. protein kinase cAMP-dep…
  4. 0.751
  5. Metabolic
- 2. PRDX6
  3. peroxiredoxin 6
  4. 0.726
  5. Metabolic
- 2. PRKAR2B
  3. protein kinase cAMP-dep…
  4. 0.710
  5. Metabolic
- 2. TMBIM1
  3. transmembrane BAX inhib…
  4. 0.700
  5. Metabolic
- 2. SLC44A4
  3. solute carrier family 4…
  4. 0.654
  5. Metabolic
- 2. WDR1
  3. WD repeat domain 1
  4. 0.526
  5. Metabolic
- 2. GBE1
  3. 1,4-alpha-glucan branch…
  4. 0.498
  5. Metabolic
- 2. SLC44A2
  3. solute carrier family 4…
  4. 0.495
  5. Metabolic
- 2. ABAT
  3. 4-aminobutyrate aminotr…
  4. 0.487
  5. Metabolic
- 2. SLC44A1
  3. solute carrier family 4…
  4. 0.466
  5. Metabolic
- 2. SELENOO
  3. selenoprotein O
  4. 0.435
  5. Metabolic
- 2. SLC44A3
  3. solute carrier family 4…
  4. 0.421
  5. Metabolic
- 2. TP53I3
  3. tumor protein p53 induc…
  4. 0.408
  5. Metabolic
- 2. MPV17
  3. mitochondrial inner mem…
  4. 0.403
  5. Metabolic

Subnetwork gene interactions

ENSG00000143839

renin

FunCoup

Use as query
Use pair as query
Add to current query

Ensembl

ENSG00000143839

UniProt

NCBI

5972

GYS2

glycogen synthase 2

FunCoup

Use as query
Use pair as query
Add to current query

Ensembl

ENSG00000111713

UniProt

P54840

NCBI

2998

SLC44A1

solute carrier family 44 member 1

FunCoup

Use as query
Use pair as query
Add to current query

Ensembl

ENSG00000070214

UniProt

Q8WWI5

NCBI

23446

TMBIM1

transmembrane BAX inhibitor motif containing 1

FunCoup

Use as query
Use pair as query
Add to current query

Ensembl

ENSG00000135926

UniProt

NCBI

64114

SLC44A2

solute carrier family 44 member 2

FunCoup

Use as query
Use pair as query
Add to current query

Ensembl

ENSG00000129353

UniProt

NCBI

57153

GBE1

1,4-alpha-glucan branching enzyme 1

FunCoup

Use as query
Use pair as query
Add to current query

Ensembl

ENSG00000114480

UniProt

NCBI

2632

CTSA

cathepsin A

FunCoup

Use as query
Use pair as query
Add to current query

Ensembl

ENSG00000064601

UniProt

NCBI

5476

BBOX1

gamma-butyrobetaine hydroxylase 1

FunCoup

Use as query
Use pair as query
Add to current query

Ensembl

ENSG00000129151

UniProt

NCBI

8424

PRDX6

peroxiredoxin 6

FunCoup

Use as query
Use pair as query
Add to current query

Ensembl

ENSG00000117592

UniProt

P30041

NCBI

9588

GRHPR

glyoxylate and hydroxypyruvate reductase

FunCoup

Use as query
Use pair as query
Add to current query

Ensembl

ENSG00000137106

UniProt

NCBI

9380

MPV17

mitochondrial inner membrane protein MPV17

FunCoup

Use as query
Use pair as query
Add to current query

Ensembl

ENSG00000115204

UniProt

NCBI

4358

DCPS

decapping enzyme, scavenger

FunCoup

Use as query
Use pair as query
Add to current query

Ensembl

ENSG00000110063

UniProt

NCBI

28960

SLC44A3

solute carrier family 44 member 3

FunCoup

Use as query
Use pair as query
Add to current query

Ensembl

ENSG00000143036

UniProt

NCBI

126969

SLC25A3

solute carrier family 25 member 3

FunCoup

Use as query
Use pair as query
Add to current query

Ensembl

ENSG00000075415

UniProt

NCBI

5250

PRKAR2B

protein kinase cAMP-dependent type II regulatory subunit beta

FunCoup

Use as query
Use pair as query
Add to current query

Ensembl

ENSG00000005249

UniProt

P31323

NCBI

5577

GYS1

glycogen synthase 1

FunCoup

Use as query
Use pair as query
Add to current query

Ensembl

ENSG00000104812

UniProt

NCBI

2997

SLC44A4

solute carrier family 44 member 4

FunCoup

Use as query
Use pair as query
Add to current query

Ensembl

ENSG00000204385

UniProt

NCBI

80736

WDR1

WD repeat domain 1

FunCoup

Use as query
Use pair as query
Add to current query

Ensembl

ENSG00000071127

UniProt

NCBI

9948

TMLHE

trimethyllysine hydroxylase, epsilon

FunCoup

Use as query
Use pair as query
Add to current query

Ensembl

ENSG00000185973

UniProt

Q9NVH6

NCBI

55217

VCP

valosin containing protein

FunCoup

Use as query
Use pair as query
Add to current query

Ensembl

ENSG00000165280

UniProt

NCBI

7415

ABAT

4-aminobutyrate aminotransferase

FunCoup

Use as query
Use pair as query
Add to current query

Ensembl

ENSG00000183044

UniProt

NCBI

DHDH

dihydrodiol dehydrogenase

FunCoup

Use as query
Use pair as query
Add to current query

Ensembl

ENSG00000104808

UniProt

NCBI

27294

PRKAR2A

protein kinase cAMP-dependent type II regulatory subunit alpha

FunCoup

Use as query
Use pair as query
Add to current query

Ensembl

ENSG00000114302

UniProt

NCBI

5576

AGL

amylo-alpha-1, 6-glucosidase, 4-alpha-glucanotransferase

FunCoup

Use as query
Use pair as query
Add to current query

Ensembl

ENSG00000162688

UniProt

NCBI

SELENOO

selenoprotein O

FunCoup

Use as query
Use pair as query
Add to current query

Ensembl

ENSG00000073169

UniProt

NCBI

83642

TP53I3

tumor protein p53 inducible protein 3

FunCoup

Use as query
Use pair as query
Add to current query

Ensembl

ENSG00000115129

UniProt

NCBI

9540

Query genes

		Identifier	Description
25	ENSG00000143839	ENSG00000143839	renin
		UniProt	A0A1B0GUZ2 P00797
		NCBI	5972
		KEGG signaling	Renin-angiotensin system

Subnetwork genes

		Identifier	Description
16	GYS2	ENSG00000111713	glycogen synthase 2
		UniProt	P54840
		NCBI	2998
		KEGG signaling	AMPK signaling pathway PI3K-Akt signaling pathway Glucagon signaling pathway Insulin signaling pathway
		KEGG metabolic	Starch and sucrose metabolism
20	SLC44A1	ENSG00000070214	solute carrier family 44 member 1
		UniProt	Q8WWI5
		NCBI	23446
18	TMBIM1	ENSG00000135926	transmembrane BAX inhibitor motif containing 1
		UniProt	A0A1D5RMQ2 B3KSM0 B4DUD2 C9IYT2 C9IZ27 C9JAK9 C9JAP5 C9JDV0 C9JEN3 C9JI44 C9JM62 C9JN47 C9JW19 C9JWV9 F8WDY4 Q969X1
		NCBI	64114
16	SLC44A2	ENSG00000129353	solute carrier family 44 member 2
		UniProt	A0A140TA83 K7EMN3 K7EMR2 K7EPV6 K7ER17 K7ESF5 K7ESP7 Q8IWA5
		NCBI	57153
20	GBE1	ENSG00000114480	1,4-alpha-glucan branching enzyme 1
		UniProt	E9PGM4 Q04446
		NCBI	2632
		KEGG metabolic	Starch and sucrose metabolism
17	CTSA	ENSG00000064601	cathepsin A
		UniProt	P10619 Q5JZH0 U3KQ41 U3KQF1 U3KQU6 X6R5C5 X6R8A1
		NCBI	5476
		KEGG signaling	Renin-angiotensin system
		KEGG metabolic	Lysosome
19	BBOX1	ENSG00000129151	gamma-butyrobetaine hydroxylase 1
		UniProt	E9PKC9 O75936
		NCBI	8424
		KEGG metabolic	Lysine degradation
25	PRDX6	ENSG00000117592	peroxiredoxin 6
		UniProt	P30041
		NCBI	9588
		KEGG metabolic	Glutathione metabolism
24	GRHPR	ENSG00000137106	glyoxylate and hydroxypyruvate reductase
		UniProt	Q9UBQ7 U3KQ56
		NCBI	9380
		KEGG metabolic	Pyruvate metabolism Glycine, serine and threonine metabolism Glyoxylate and dicarboxylate metabolism
17	MPV17	ENSG00000115204	mitochondrial inner membrane protein MPV17
		UniProt	A8MPV4 A8MTD3 B5MC10 B5MC53 B5MCF8 C9J473 E7EX18 F8WEL3 G5E9F5 H0Y6M5 P39210
		NCBI	4358
		KEGG metabolic	Peroxisome
24	DCPS	ENSG00000110063	decapping enzyme, scavenger
		UniProt	A0A3B3ITF0 Q96C86
		NCBI	28960
		KEGG metabolic	RNA degradation
14	SLC44A3	ENSG00000143036	solute carrier family 44 member 3
		UniProt	E9PIC5 F8W7F3 H0YD35 H0YDW5 Q8N4M1
		NCBI	126969
23	SLC25A3	ENSG00000075415	solute carrier family 25 member 3
		UniProt	F8VVM2 F8VWQ0 F8VWR4 F8VY00 F8VYH5 F8VZL5 Q00325
		NCBI	5250
15	PRKAR2B	ENSG00000005249	protein kinase cAMP-dependent type II regulatory subunit beta
		UniProt	P31323
		NCBI	5577
		KEGG signaling	Insulin signaling pathway
19	GYS1	ENSG00000104812	glycogen synthase 1
		UniProt	M0QYU1 P13807
		NCBI	2997
		KEGG signaling	AMPK signaling pathway PI3K-Akt signaling pathway Glucagon signaling pathway Insulin signaling pathway
		KEGG metabolic	Starch and sucrose metabolism
19	SLC44A4	ENSG00000204385	solute carrier family 44 member 4
		UniProt	H0Y5I3 Q53GD3
		NCBI	80736
14	WDR1	ENSG00000071127	WD repeat domain 1
		UniProt	D6RD66 O75083
		NCBI	9948
17	TMLHE	ENSG00000185973	trimethyllysine hydroxylase, epsilon
		UniProt	Q9NVH6
		NCBI	55217
		KEGG metabolic	Lysine degradation
18	VCP	ENSG00000165280	valosin containing protein
		UniProt	C9IZA5 C9JUP7 P55072
		NCBI	7415
		KEGG metabolic	Protein processing in endoplasmic reticulum
7	ABAT	ENSG00000183044	4-aminobutyrate aminotransferase
		UniProt	H3BMJ9 H3BNQ7 H3BP74 H3BP84 H3BPW8 H3BRJ1 H3BRN4 H3BRT1 P80404
		NCBI	18
		KEGG signaling	GABAergic synapse
		KEGG metabolic	Valine, leucine and isoleucine degradation Alanine, aspartate and glutamate metabolism Butanoate metabolism beta-Alanine metabolism Propanoate metabolism
12	DHDH	ENSG00000104808	dihydrodiol dehydrogenase
		UniProt	E5RFE0 E5RGT8 H0YBU7 Q9UQ10
		NCBI	27294
		KEGG metabolic	Pentose and glucuronate interconversions Metabolism of xenobiotics by cytochrome P450
17	PRKAR2A	ENSG00000114302	protein kinase cAMP-dependent type II regulatory subunit alpha
		UniProt	C9J830 H7C1L0 H7C330 H7C4A9 P13861
		NCBI	5576
		KEGG signaling	Insulin signaling pathway
22	AGL	ENSG00000162688	amylo-alpha-1, 6-glucosidase, 4-alpha-glucanotransferase
		UniProt	A0A1C7CYW1 P35573
		NCBI	178
		KEGG metabolic	Starch and sucrose metabolism
14	SELENOO	ENSG00000073169	selenoprotein O
		UniProt	A0A087X0Q9 Q9BVL4
		NCBI	83642
6	TP53I3	ENSG00000115129	tumor protein p53 inducible protein 3
		UniProt	H7BZH6 Q53FA7
		NCBI	9540
		KEGG signaling	p53 signaling pathway

Enrichment analysis

Search for enrichment of pathways or functional gene sets for your subnetwork genes

To use PathwAX, first use the button below to copy the subnetwork genes and then paste them in PathwAX

Copied subnetwork genes to clipboard

Use as query
Add to current query

	jSquid_subnetworks.xml	202.24 KB
	H.sapiens_subnetwork.tsv	40.64 KB

Species:

Network information:

Filter Results:

Network appearance:

ENSG00000143839

GYS2

SLC44A1

TMBIM1

SLC44A2

GBE1

CTSA

BBOX1

PRDX6

GRHPR

MPV17

DCPS

SLC44A3

SLC25A3

PRKAR2B

GYS1

SLC44A4

WDR1

TMLHE

VCP

ABAT

DHDH

PRKAR2A

AGL

SELENOO

TP53I3

JavaScript is required.