Found 1 of 1 query genes

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Query interactions

Interaction partners
Confidence
Network
MEX
PIN
SCL
PHP
MIR
TFB
PEX
GIN
DOM
QMS
GRG
Evidence types
HSA
MMU
RNO
CFA
GGA
DRE
CIN
DME
CEL
BTA
SCE
ATH
SPO
BSU
ECO
PFA
DDI
SSO
SSC
MJA
OSA
Species
In Gold st.

ID Query gene
ID Query ortholog

Log-likelihood ratio (LLR)
	Highly positive
	Positive
	Zero
	Negative
	Highly negative
Known coupling
	This network
	Other network

2. ENSG00000136156
3. integral membrane prote…
- 2. GLG1
  3. golgi glycoprotein 1
  4. 1.000
  5. PPI
- 2. APP
  3. amyloid beta precursor …
  4. 0.995
  5. PPI
- 2. CHST12
  3. carbohydrate sulfotrans…
  4. 0.992
  5. PPI
- 2. HSPA5
  3. heat shock protein fami…
  4. 0.990
  5. PPI
- 2. TGFBR3
  3. transforming growth fac…
  4. 0.988
  5. PPI
- 2. TM9SF2
  3. transmembrane 9 superfa…
  4. 0.985
  5. Metabolic
- 2. MR1
  3. major histocompatibilit…
  4. 0.984
  5. PPI
- 2. QSOX1
  3. quiescin sulfhydryl oxi…
  4. 0.975
  5. PPI
- 2. ATF6B
  3. activating transcriptio…
  4. 0.974
  5. PPI
- 2. NUCB1
  3. nucleobindin 1
  4. 0.971
  5. Metabolic
- 2. TMED2
  3. transmembrane p24 traff…
  4. 0.967
  5. Metabolic
- 2. RAB1A
  3. RAB1A, member RAS oncog…
  4. 0.967
  5. PPI
- 2. CALR
  3. calreticulin
  4. 0.963
  5. Metabolic
- 2. B4GALNT1
  3. beta-1,4-N-acetyl-galac…
  4. 0.962
  5. PPI
- 2. AP1M1
  3. adaptor related protein…
  4. 0.960
  5. PPI
- 2. PDIA3
  3. protein disulfide isome…
  4. 0.958
  5. Metabolic
- 2. P4HB
  3. prolyl 4-hydroxylase su…
  4. 0.949
  5. PPI
- 2. LAMP1
  3. lysosomal associated me…
  4. 0.948
  5. Complex
- 2. TMEM219
  3. transmembrane protein 2…
  4. 0.948
  5. PPI
- 2. LMNA
  3. lamin A/C
  4. 0.944
  5. PPI
- 2. RAB7A
  3. RAB7A, member RAS oncog…
  4. 0.943
  5. PPI
- 2. LMAN2
  3. lectin, mannose binding…
  4. 0.943
  5. Metabolic
- 2. SLC2A1
  3. solute carrier family 2…
  4. 0.941
  5. PPI
- 2. EEF1A1
  3. eukaryotic translation …
  4. 0.940
  5. PPI
- 2. CHMP2A
  3. charged multivesicular …
  4. 0.940
  5. Metabolic
- 2. RAB6A
  3. RAB6A, member RAS oncog…
  4. 0.936
  5. Complex
- 2. KDELR2
  3. KDEL endoplasmic reticu…
  4. 0.936
  5. Metabolic
- 2. PPIB
  3. peptidylprolyl isomeras…
  4. 0.926
  5. Metabolic
- 2. ATP6V0C
  3. ATPase H+ transporting …
  4. 0.902
  5. PPI
- 2. ATP6V0D1
  3. ATPase H+ transporting …
  4. 0.900
  5. Metabolic

Subnetwork gene interactions

ENSG00000136156

integral membrane protein 2B

FunCoup

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Ensembl

ENSG00000136156

UniProt

NCBI

9445

EEF1A1

eukaryotic translation elongation factor 1 alpha 1

FunCoup

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Ensembl

ENSG00000156508

UniProt

NCBI

1915

CHMP2A

charged multivesicular body protein 2A

FunCoup

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Ensembl

ENSG00000130724

UniProt

NCBI

27243

TM9SF2

transmembrane 9 superfamily member 2

FunCoup

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Ensembl

ENSG00000125304

UniProt

NCBI

9375

MR1

major histocompatibility complex, class I-related

FunCoup

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Ensembl

ENSG00000153029

UniProt

Q95460

NCBI

3140

PPIB

peptidylprolyl isomerase B

FunCoup

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Ensembl

ENSG00000166794

UniProt

P23284

NCBI

5479

RAB7A

RAB7A, member RAS oncogene family

FunCoup

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Ensembl

ENSG00000075785

UniProt

NCBI

7879

RAB1A

RAB1A, member RAS oncogene family

FunCoup

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Ensembl

ENSG00000138069

UniProt

NCBI

5861

HSPA5

heat shock protein family A (Hsp70) member 5

FunCoup

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Ensembl

ENSG00000044574

UniProt

P11021

NCBI

3309

SLC2A1

solute carrier family 2 member 1

FunCoup

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Ensembl

ENSG00000117394

UniProt

NCBI

6513

QSOX1

quiescin sulfhydryl oxidase 1

FunCoup

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Ensembl

ENSG00000116260

UniProt

NCBI

5768

PDIA3

protein disulfide isomerase family A member 3

FunCoup

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Ensembl

ENSG00000167004

UniProt

NCBI

2923

CALR

calreticulin

FunCoup

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Ensembl

ENSG00000179218

UniProt

NCBI

GLG1

golgi glycoprotein 1

FunCoup

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Ensembl

ENSG00000090863

UniProt

NCBI

2734

ATP6V0C

ATPase H+ transporting V0 subunit c

FunCoup

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Ensembl

ENSG00000185883

UniProt

NCBI

ATP6V0D1

ATPase H+ transporting V0 subunit d1

FunCoup

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Ensembl

ENSG00000159720

UniProt

NCBI

9114

AP1M1

adaptor related protein complex 1 subunit mu 1

FunCoup

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Ensembl

ENSG00000072958

UniProt

NCBI

8907

KDELR2

KDEL endoplasmic reticulum protein retention receptor 2

FunCoup

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Ensembl

ENSG00000136240

UniProt

NCBI

11014

NUCB1

nucleobindin 1

FunCoup

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Ensembl

ENSG00000104805

UniProt

NCBI

4924

RAB6A

RAB6A, member RAS oncogene family

FunCoup

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Ensembl

ENSG00000175582

UniProt

NCBI

5870

TMED2

transmembrane p24 trafficking protein 2

FunCoup

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Ensembl

ENSG00000086598

UniProt

NCBI

10959

TMEM219

transmembrane protein 219

FunCoup

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Ensembl

ENSG00000149932

UniProt

NCBI

124446

LAMP1

lysosomal associated membrane protein 1

FunCoup

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Ensembl

ENSG00000185896

UniProt

P11279

NCBI

3916

LMNA

lamin A/C

FunCoup

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Ensembl

ENSG00000160789

UniProt

NCBI

4000

LMAN2

lectin, mannose binding 2

FunCoup

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Ensembl

ENSG00000169223

UniProt

NCBI

10960

APP

amyloid beta precursor protein

FunCoup

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Ensembl

ENSG00000142192

UniProt

NCBI

P4HB

prolyl 4-hydroxylase subunit beta

FunCoup

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Ensembl

ENSG00000185624

UniProt

NCBI

5034

B4GALNT1

beta-1,4-N-acetyl-galactosaminyltransferase 1

FunCoup

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Ensembl

ENSG00000135454

UniProt

NCBI

2583

ATF6B

activating transcription factor 6 beta

FunCoup

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Ensembl

ENSG00000213676

UniProt

NCBI

1388

TGFBR3

transforming growth factor beta receptor 3

FunCoup

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Ensembl

ENSG00000069702

UniProt

NCBI

7049

CHST12

carbohydrate sulfotransferase 12

FunCoup

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Ensembl

ENSG00000136213

UniProt

NCBI

55501

Query genes

		Identifier	Description
30	ENSG00000136156	ENSG00000136156	integral membrane protein 2B
		UniProt	A0A3B3ISG3 A0A3B3ITP9 A0A3B3IU60 A0A3B3IUC0 Q9Y287 U3KQ52 U3KQL7
		NCBI	9445

Subnetwork genes

		Identifier	Description
23	EEF1A1	ENSG00000156508	eukaryotic translation elongation factor 1 alpha 1
		UniProt	A0A087WV01 A0A087WVQ9 A6PW80 P68104 Q5JR01
		NCBI	1915
		KEGG metabolic	RNA transport
21	CHMP2A	ENSG00000130724	charged multivesicular body protein 2A
		UniProt	M0QXX8 M0R1L7 M0R1T5 O43633
		NCBI	27243
		KEGG metabolic	Endocytosis
25	TM9SF2	ENSG00000125304	transmembrane 9 superfamily member 2
		UniProt	A0A2R8Y4S7 Q99805
		NCBI	9375
2	MR1	ENSG00000153029	major histocompatibility complex, class I-related
		UniProt	Q95460
		NCBI	3140
22	PPIB	ENSG00000166794	peptidylprolyl isomerase B
		UniProt	P23284
		NCBI	5479
20	RAB7A	ENSG00000075785	RAB7A, member RAS oncogene family
		UniProt	C9IZZ0 C9J4S4 C9J4V0 C9J592 C9J7D1 C9J8S3 P51149
		NCBI	7879
		KEGG metabolic	Phagosome Endocytosis Autophagy - animal
20	RAB1A	ENSG00000138069	RAB1A, member RAS oncogene family
		UniProt	E7END7 P62820
		NCBI	5861
		KEGG metabolic	Autophagy - animal
24	HSPA5	ENSG00000044574	heat shock protein family A (Hsp70) member 5
		UniProt	P11021
		NCBI	3309
		KEGG signaling	Antigen processing and presentation
		KEGG metabolic	Protein export Protein processing in endoplasmic reticulum
19	SLC2A1	ENSG00000117394	solute carrier family 2 member 1
		UniProt	A0A0D9SFK9 A0A0D9SG74 A0A1W2PQ59 A0A590UJ26 A6NL68 P11166
		NCBI	6513
		KEGG signaling	Adipocytokine signaling pathway Thyroid hormone signaling pathway HIF-1 signaling pathway Glucagon signaling pathway
17	QSOX1	ENSG00000116260	quiescin sulfhydryl oxidase 1
		UniProt	A8MXT8 H0Y5Z8 O00391
		NCBI	5768
24	PDIA3	ENSG00000167004	protein disulfide isomerase family A member 3
		UniProt	F8WBS6 F8WBW5 H7BZJ3 P30101
		NCBI	2923
		KEGG signaling	Antigen processing and presentation
		KEGG metabolic	Protein processing in endoplasmic reticulum
25	CALR	ENSG00000179218	calreticulin
		UniProt	K7EJB9 K7EL50 K7ELE2 P27797
		NCBI	811
		KEGG signaling	Antigen processing and presentation
		KEGG metabolic	Phagosome Protein processing in endoplasmic reticulum
12	GLG1	ENSG00000090863	golgi glycoprotein 1
		UniProt	H3BM42 H3BQT1 H3BQU9 H3BRD8 Q92896
		NCBI	2734
		KEGG signaling	Cell adhesion molecules (CAMs)
21	ATP6V0C	ENSG00000185883	ATPase H+ transporting V0 subunit c
		UniProt	H3BMY0 H3BNI4 P27449
		NCBI	527
		KEGG signaling	Synaptic vesicle cycle
		KEGG metabolic	Oxidative phosphorylation Phagosome Lysosome
23	ATP6V0D1	ENSG00000159720	ATPase H+ transporting V0 subunit d1
		UniProt	F5GYQ1 F8WEN9 H3BPS0 H3BQB4 H3BQJ1 H3BSG7 H3BTB4 H3BTB5 H3BUQ0 J3QL14 P61421 R4GN72
		NCBI	9114
		KEGG signaling	Synaptic vesicle cycle
		KEGG metabolic	Oxidative phosphorylation Phagosome Lysosome
21	AP1M1	ENSG00000072958	adaptor related protein complex 1 subunit mu 1
		UniProt	A0A087WZX7 E7ENJ6 K7EJL1 K7ENA7 K7EPJ8 K7EQ90 K7EQX3 K7ER75 Q9BXS5
		NCBI	8907
		KEGG metabolic	Lysosome
21	KDELR2	ENSG00000136240	KDEL endoplasmic reticulum protein retention receptor 2
		UniProt	H7BYF7 P33947
		NCBI	11014
24	NUCB1	ENSG00000104805	nucleobindin 1
		UniProt	C9J3C1 C9JBD3 C9JKZ2 F8WB20 H7BZI1 Q02818
		NCBI	4924
21	RAB6A	ENSG00000175582	RAB6A, member RAS oncogene family
		UniProt	F5GX61 F5H3K7 P20340
		NCBI	5870
21	TMED2	ENSG00000086598	transmembrane p24 trafficking protein 2
		UniProt	E7EQ72 F5GX39 Q15363
		NCBI	10959
1	TMEM219	ENSG00000149932	transmembrane protein 219
		UniProt	H3BML8 I3L2J7 I3L4B3 Q86XT9
		NCBI	124446
20	LAMP1	ENSG00000185896	lysosomal associated membrane protein 1
		UniProt	P11279
		NCBI	3916
		KEGG metabolic	Phagosome Lysosome Autophagy - animal
6	LMNA	ENSG00000160789	lamin A/C
		UniProt	A0A0C4DGC5 D6RB20 H0YAB0 P02545 Q3BDU5 Q5TCI8
		NCBI	4000
		KEGG signaling	Apoptosis
22	LMAN2	ENSG00000169223	lectin, mannose binding 2
		UniProt	D6RBH1 D6RBV2 D6RDX1 D6RIU4 Q12907
		NCBI	10960
		KEGG metabolic	Protein processing in endoplasmic reticulum
16	APP	ENSG00000142192	amyloid beta precursor protein
		UniProt	A0A0A0MRG2 E9PG40 H7C0V9 H7C2L2 P05067
		NCBI	351
		KEGG signaling	Serotonergic synapse
24	P4HB	ENSG00000185624	prolyl 4-hydroxylase subunit beta
		UniProt	H0Y3Z3 H7BZ94 I3L0S0 I3L1Y5 I3L312 I3L398 I3L3P5 I3L3U6 I3L4M2 I3L514 I3NI03 P07237
		NCBI	5034
		KEGG metabolic	Protein processing in endoplasmic reticulum
1	B4GALNT1	ENSG00000135454	beta-1,4-N-acetyl-galactosaminyltransferase 1
		UniProt	B4DSP5 F8VR44 F8VSE0 F8VU35 F8VW33 F8W1A7 H0YHT1 H0YI57 Q00973
		NCBI	2583
		KEGG metabolic	Glycosphingolipid biosynthesis - ganglio series
6	ATF6B	ENSG00000213676	activating transcription factor 6 beta
		UniProt	H0Y7D7 Q99941
		NCBI	1388
		KEGG signaling	cGMP-PKG signaling pathway Relaxin signaling pathway Estrogen signaling pathway Dopaminergic synapse Adrenergic signaling in cardiomyocytes PI3K-Akt signaling pathway TNF signaling pathway
		KEGG metabolic	Protein processing in endoplasmic reticulum
1	TGFBR3	ENSG00000069702	transforming growth factor beta receptor 3
		UniProt	E9PAW7 E9PKY4 E9PMG7 Q03167
		NCBI	7049
1	CHST12	ENSG00000136213	carbohydrate sulfotransferase 12
		UniProt	C9J991 Q9NRB3
		NCBI	55501
		KEGG metabolic	Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate

Enrichment analysis

Search for enrichment of pathways or functional gene sets for your subnetwork genes

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	jSquid_subnetworks.xml	291.72 KB
	H.sapiens_subnetwork.tsv	49.48 KB

Species:

Network information:

Filter Results:

Network appearance:

ENSG00000136156

EEF1A1

CHMP2A

TM9SF2

MR1

PPIB

RAB7A

RAB1A

HSPA5

SLC2A1

QSOX1

PDIA3

CALR

GLG1

ATP6V0C

ATP6V0D1

AP1M1

KDELR2

NUCB1

RAB6A

TMED2

TMEM219

LAMP1

LMNA

LMAN2

APP

P4HB

B4GALNT1

ATF6B

TGFBR3

CHST12

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