Found 1 of 1 query genes

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Query interactions

Interaction partners
Confidence
Network
MEX
PIN
SCL
PHP
MIR
TFB
PEX
GIN
DOM
QMS
GRG
Evidence types
HSA
MMU
RNO
CFA
GGA
DRE
CIN
DME
CEL
BTA
SCE
ATH
SPO
BSU
ECO
PFA
DDI
SSO
SSC
MJA
OSA
Species
In Gold st.

ID Query gene
ID Query ortholog

Log-likelihood ratio (LLR)
	Highly positive
	Positive
	Zero
	Negative
	Highly negative
Known coupling
	This network
	Other network

2. ENSG00000134108
3. ADP ribosylation factor…
- 2. TUBB
  3. tubulin beta class I
  4. 1.000
  5. PPI
- 2. VPS4A
  3. vacuolar protein sortin…
  4. 0.999
  5. PPI
- 2. SDF4
  3. stromal cell derived fa…
  4. 0.999
  5. PPI
- 2. SRPRB
  3. SRP receptor subunit be…
  4. 0.997
  5. PPI
- 2. WWP1
  3. WW domain containing E3…
  4. 0.994
  5. PPI
- 2. APP
  3. amyloid beta precursor …
  4. 0.992
  5. PPI
- 2. CAP1
  3. cyclase associated acti…
  4. 0.992
  5. Metabolic
- 2. TBC1D22B
  3. TBC1 domain family memb…
  4. 0.990
  5. PPI
- 2. ATP6V1B1
  3. ATPase H+ transporting …
  4. 0.986
  5. PPI
- 2. ATP6V1D
  3. ATPase H+ transporting …
  4. 0.986
  5. Metabolic
- 2. HSPA8
  3. heat shock protein fami…
  4. 0.981
  5. Metabolic
- 2. GNAI3
  3. G protein subunit alpha…
  4. 0.980
  5. Metabolic
- 2. ATP6V0D1
  3. ATPase H+ transporting …
  4. 0.980
  5. Metabolic
- 2. VPS35
  3. VPS35 retromer complex …
  4. 0.980
  5. Metabolic
- 2. ARL8A
  3. ADP ribosylation factor…
  4. 0.978
  5. Metabolic
- 2. DDOST
  3. dolichyl-diphosphooligo…
  4. 0.976
  5. Metabolic
- 2. ARPC2
  3. actin related protein 2…
  4. 0.976
  5. Metabolic
- 2. CLTC
  3. clathrin heavy chain
  4. 0.976
  5. Metabolic
- 2. UBA1
  3. ubiquitin like modifier…
  4. 0.975
  5. Metabolic
- 2. PPT1
  3. palmitoyl-protein thioe…
  4. 0.974
  5. Metabolic
- 2. VTA1
  3. vesicle trafficking 1
  4. 0.972
  5. Metabolic
- 2. ACTR2
  3. actin related protein 2
  4. 0.972
  5. Metabolic
- 2. SEC13
  3. SEC13 homolog, nuclear …
  4. 0.972
  5. Metabolic
- 2. HCCS
  3. holocytochrome c syntha…
  4. 0.971
  5. PPI
- 2. TM9SF2
  3. transmembrane 9 superfa…
  4. 0.970
  5. Metabolic
- 2. TMEM30A
  3. transmembrane protein 3…
  4. 0.969
  5. Metabolic
- 2. ATP6V1C1
  3. ATPase H+ transporting …
  4. 0.969
  5. Metabolic
- 2. ATP6V1E1
  3. ATPase H+ transporting …
  4. 0.968
  5. Metabolic
- 2. ARF1
  3. ADP ribosylation factor…
  4. 0.967
  5. Metabolic
- 2. CHMP5
  3. charged multivesicular …
  4. 0.966
  5. Metabolic

Subnetwork gene interactions

ENSG00000134108

ADP ribosylation factor like GTPase 8B

FunCoup

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Ensembl

ENSG00000134108

UniProt

NCBI

55207

SRPRB

SRP receptor subunit beta

FunCoup

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Ensembl

ENSG00000144867

UniProt

NCBI

58477

SEC13

SEC13 homolog, nuclear pore and COPII coat complex component

FunCoup

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Ensembl

ENSG00000157020

UniProt

NCBI

6396

ARF1

ADP ribosylation factor 1

FunCoup

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Ensembl

ENSG00000143761

UniProt

P84077

NCBI

HCCS

holocytochrome c synthase

FunCoup

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Ensembl

ENSG00000004961

UniProt

P53701

NCBI

3052

CAP1

cyclase associated actin cytoskeleton regulatory protein 1

FunCoup

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Ensembl

ENSG00000131236

UniProt

NCBI

10487

VPS35

VPS35 retromer complex component

FunCoup

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Ensembl

ENSG00000069329

UniProt

NCBI

55737

HSPA8

heat shock protein family A (Hsp70) member 8

FunCoup

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Ensembl

ENSG00000109971

UniProt

NCBI

3312

GNAI3

G protein subunit alpha i3

FunCoup

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Ensembl

ENSG00000065135

UniProt

P08754

NCBI

2773

VPS4A

vacuolar protein sorting 4 homolog A

FunCoup

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Ensembl

ENSG00000132612

UniProt

Q9UN37

NCBI

27183

TUBB

tubulin beta class I

FunCoup

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Ensembl

ENSG00000196230

UniProt

NCBI

203068

ACTR2

actin related protein 2

FunCoup

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Ensembl

ENSG00000138071

UniProt

NCBI

10097

TMEM30A

transmembrane protein 30A

FunCoup

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Ensembl

ENSG00000112697

UniProt

NCBI

55754

CLTC

clathrin heavy chain

FunCoup

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Ensembl

ENSG00000141367

UniProt

NCBI

1213

VTA1

vesicle trafficking 1

FunCoup

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Ensembl

ENSG00000009844

UniProt

NCBI

51534

ARPC2

actin related protein 2/3 complex subunit 2

FunCoup

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Ensembl

ENSG00000163466

UniProt

NCBI

10109

DDOST

dolichyl-diphosphooligosaccharide--protein glycosyltransferase non-catalytic subunit

FunCoup

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Ensembl

ENSG00000244038

UniProt

NCBI

1650

ATP6V1E1

ATPase H+ transporting V1 subunit E1

FunCoup

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Ensembl

ENSG00000131100

UniProt

NCBI

ATP6V1D

ATPase H+ transporting V1 subunit D

FunCoup

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Ensembl

ENSG00000100554

UniProt

NCBI

51382

ATP6V1C1

ATPase H+ transporting V1 subunit C1

FunCoup

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Ensembl

ENSG00000155097

UniProt

NCBI

APP

amyloid beta precursor protein

FunCoup

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Ensembl

ENSG00000142192

UniProt

NCBI

ATP6V1B1

ATPase H+ transporting V1 subunit B1

FunCoup

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Ensembl

ENSG00000116039

UniProt

NCBI

ATP6V0D1

ATPase H+ transporting V0 subunit d1

FunCoup

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Ensembl

ENSG00000159720

UniProt

NCBI

9114

UBA1

ubiquitin like modifier activating enzyme 1

FunCoup

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Ensembl

ENSG00000130985

UniProt

NCBI

7317

TBC1D22B

TBC1 domain family member 22B

FunCoup

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Ensembl

ENSG00000065491

UniProt

Q9NU19

NCBI

55633

TM9SF2

transmembrane 9 superfamily member 2

FunCoup

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Ensembl

ENSG00000125304

UniProt

NCBI

9375

CHMP5

charged multivesicular body protein 5

FunCoup

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Ensembl

ENSG00000086065

UniProt

Q9NZZ3

NCBI

51510

SDF4

stromal cell derived factor 4

FunCoup

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Ensembl

ENSG00000078808

UniProt

NCBI

51150

ARL8A

ADP ribosylation factor like GTPase 8A

FunCoup

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Ensembl

ENSG00000143862

UniProt

NCBI

127829

PPT1

palmitoyl-protein thioesterase 1

FunCoup

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Ensembl

ENSG00000131238

UniProt

NCBI

5538

WWP1

WW domain containing E3 ubiquitin protein ligase 1

FunCoup

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Ensembl

ENSG00000123124

UniProt

NCBI

11059

Query genes

		Identifier	Description
30	ENSG00000134108	ENSG00000134108	ADP ribosylation factor like GTPase 8B
		UniProt	F2Z344 F8WAW5 Q9NVJ2
		NCBI	55207

Subnetwork genes

		Identifier	Description
16	SRPRB	ENSG00000144867	SRP receptor subunit beta
		UniProt	C9J5Z8 H7C4H2 Q9Y5M8
		NCBI	58477
		KEGG metabolic	Protein export
28	SEC13	ENSG00000157020	SEC13 homolog, nuclear pore and COPII coat complex component
		UniProt	A8MXL6 C9J0S2 C9JBJ5 C9JIB6 E7ERC8 P55735
		NCBI	6396
		KEGG signaling	mTOR signaling pathway
		KEGG metabolic	Protein processing in endoplasmic reticulum RNA transport
27	ARF1	ENSG00000143761	ADP ribosylation factor 1
		UniProt	P84077
		NCBI	375
		KEGG signaling	Phospholipase D signaling pathway
		KEGG metabolic	Endocytosis
10	HCCS	ENSG00000004961	holocytochrome c synthase
		UniProt	P53701
		NCBI	3052
		KEGG metabolic	Porphyrin and chlorophyll metabolism
28	CAP1	ENSG00000131236	cyclase associated actin cytoskeleton regulatory protein 1
		UniProt	Q01518 Q5T0R1 Q5T0R2 Q5T0R3 Q5T0R4 Q5T0R5 Q5T0R6 Q5T0R7 Q5T0R8 Q5T0R9 Q5T0S3
		NCBI	10487
27	VPS35	ENSG00000069329	VPS35 retromer complex component
		UniProt	A0A1W2PP10 A0A3B3ITD4 H3BRJ7 I3L4S0 Q96QK1
		NCBI	55737
		KEGG metabolic	Endocytosis
26	HSPA8	ENSG00000109971	heat shock protein family A (Hsp70) member 8
		UniProt	A8K7Q2 E9PI65 E9PK54 E9PKE3 E9PLF4 E9PM13 E9PN25 E9PN89 E9PNE6 E9PPY6 E9PQK7 E9PQQ4 E9PS65 P11142
		NCBI	3312
		KEGG signaling	Antigen processing and presentation MAPK signaling pathway Estrogen signaling pathway
		KEGG metabolic	Spliceosome Endocytosis Protein processing in endoplasmic reticulum
27	GNAI3	ENSG00000065135	G protein subunit alpha i3
		UniProt	P08754
		NCBI	2773
		KEGG signaling	Leukocyte transendothelial migration Apelin signaling pathway Adrenergic signaling in cardiomyocytes Chemokine signaling pathway Sphingolipid signaling pathway Rap1 signaling pathway Long-term depression cAMP signaling pathway Gap junction cGMP-PKG signaling pathway Melanogenesis Dopaminergic synapse Relaxin signaling pathway Estrogen signaling pathway Progesterone-mediated oocyte maturation GABAergic synapse Serotonergic synapse Cholinergic synapse Glutamatergic synapse Retrograde endocannabinoid signaling Oxytocin signaling pathway
25	VPS4A	ENSG00000132612	vacuolar protein sorting 4 homolog A
		UniProt	Q9UN37
		NCBI	27183
		KEGG metabolic	Endocytosis
26	TUBB	ENSG00000196230	tubulin beta class I
		UniProt	P07437 Q5JP53 Q5ST81
		NCBI	203068
		KEGG signaling	Gap junction
		KEGG metabolic	Phagosome
24	ACTR2	ENSG00000138071	actin related protein 2
		UniProt	A0A1B0GWD0 A0A1B0GWH0 F5H6T1 P61160
		NCBI	10097
		KEGG signaling	Tight junction
25	TMEM30A	ENSG00000112697	transmembrane protein 30A
		UniProt	E5RG19 Q9NV96
		NCBI	55754
27	CLTC	ENSG00000141367	clathrin heavy chain
		UniProt	A0A087WVQ6 J3KRF5 J3KS13 J3KSQ2 J3KTN1 J3QL20 K7EJJ5 Q00610
		NCBI	1213
		KEGG signaling	Synaptic vesicle cycle
		KEGG metabolic	Endocytosis Lysosome
25	VTA1	ENSG00000009844	vesicle trafficking 1
		UniProt	A0A087WY55 Q5TGM0 Q9NP79
		NCBI	51534
		KEGG metabolic	Endocytosis
26	ARPC2	ENSG00000163466	actin related protein 2/3 complex subunit 2
		UniProt	C9JTV5 G5E9J0 G5E9S7 H7C3F9 O15144
		NCBI	10109
		KEGG signaling	Fc gamma R-mediated phagocytosis
		KEGG metabolic	Endocytosis
28	DDOST	ENSG00000244038	dolichyl-diphosphooligosaccharide--protein glycosyltransferase non-catalytic subunit
		UniProt	A0A0C4DGS1 P39656 U3KQ84
		NCBI	1650
		KEGG metabolic	N-Glycan biosynthesis Various types of N-glycan biosynthesis Protein processing in endoplasmic reticulum
27	ATP6V1E1	ENSG00000131100	ATPase H+ transporting V1 subunit E1
		UniProt	C9J8H1 P36543
		NCBI	529
		KEGG signaling	Synaptic vesicle cycle mTOR signaling pathway
		KEGG metabolic	Oxidative phosphorylation Phagosome
29	ATP6V1D	ENSG00000100554	ATPase H+ transporting V1 subunit D
		UniProt	G3V2S6 G3V2V6 G3V341 G3V3T8 G3V559 G3V5S7 H0YJ55 H0YJH8 H0YJS0 Q9Y5K8
		NCBI	51382
		KEGG signaling	Synaptic vesicle cycle mTOR signaling pathway
		KEGG metabolic	Oxidative phosphorylation Phagosome
25	ATP6V1C1	ENSG00000155097	ATPase H+ transporting V1 subunit C1
		UniProt	E7EV59 P21283
		NCBI	528
		KEGG signaling	Synaptic vesicle cycle mTOR signaling pathway
		KEGG metabolic	Oxidative phosphorylation Phagosome
13	APP	ENSG00000142192	amyloid beta precursor protein
		UniProt	A0A0A0MRG2 E9PG40 H7C0V9 H7C2L2 P05067
		NCBI	351
		KEGG signaling	Serotonergic synapse
19	ATP6V1B1	ENSG00000116039	ATPase H+ transporting V1 subunit B1
		UniProt	C9JL73 C9JNS9 C9JZ02 P15313
		NCBI	525
		KEGG signaling	Synaptic vesicle cycle mTOR signaling pathway
		KEGG metabolic	Oxidative phosphorylation Phagosome
28	ATP6V0D1	ENSG00000159720	ATPase H+ transporting V0 subunit d1
		UniProt	F5GYQ1 F8WEN9 H3BPS0 H3BQB4 H3BQJ1 H3BSG7 H3BTB4 H3BTB5 H3BUQ0 J3QL14 P61421 R4GN72
		NCBI	9114
		KEGG signaling	Synaptic vesicle cycle
		KEGG metabolic	Oxidative phosphorylation Phagosome Lysosome
28	UBA1	ENSG00000130985	ubiquitin like modifier activating enzyme 1
		UniProt	P22314 Q5JRR6 Q5JRR9 Q5JRS0 Q5JRS1 Q5JRS2 Q5JRS3
		NCBI	7317
		KEGG metabolic	Ubiquitin mediated proteolysis
13	TBC1D22B	ENSG00000065491	TBC1 domain family member 22B
		UniProt	Q9NU19
		NCBI	55633
28	TM9SF2	ENSG00000125304	transmembrane 9 superfamily member 2
		UniProt	A0A2R8Y4S7 Q99805
		NCBI	9375
25	CHMP5	ENSG00000086065	charged multivesicular body protein 5
		UniProt	Q9NZZ3
		NCBI	51510
		KEGG metabolic	Endocytosis
13	SDF4	ENSG00000078808	stromal cell derived factor 4
		UniProt	A0A5F9UJX7 A0A5F9UP49 G3V1E2 H0Y3T6 Q9BRK5
		NCBI	51150
23	ARL8A	ENSG00000143862	ADP ribosylation factor like GTPase 8A
		UniProt	A0A087X2J2 Q96BM9
		NCBI	127829
24	PPT1	ENSG00000131238	palmitoyl-protein thioesterase 1
		UniProt	A0A286YEP3 A0A286YF39 A0A286YFE3 A0A286YFF7 A0A286YFL6 A0A286YFL8 A0A2C9F2P4 E9PIA8 E9PK48 E9PMG2 E9PP28 E9PSE5 P50897 Q5T0S4
		NCBI	5538
		KEGG metabolic	Lysosome Fatty acid elongation Fatty acid metabolism
4	WWP1	ENSG00000123124	WW domain containing E3 ubiquitin protein ligase 1
		UniProt	H0YBA4 H0YBS9 Q9H0M0
		NCBI	11059
		KEGG metabolic	Endocytosis Ubiquitin mediated proteolysis

Enrichment analysis

Search for enrichment of pathways or functional gene sets for your subnetwork genes

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	jSquid_subnetworks.xml	309.99 KB
	H.sapiens_subnetwork.tsv	69.86 KB

Species:

Network information:

Filter Results:

Network appearance:

ENSG00000134108

SRPRB

SEC13

ARF1

HCCS

CAP1

VPS35

HSPA8

GNAI3

VPS4A

TUBB

ACTR2

TMEM30A

CLTC

VTA1

ARPC2

DDOST

ATP6V1E1

ATP6V1D

ATP6V1C1

APP

ATP6V1B1

ATP6V0D1

UBA1

TBC1D22B

TM9SF2

CHMP5

SDF4

ARL8A

PPT1

WWP1

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