Found 1 of 1 query genes

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Query interactions

Interaction partners
Confidence
Network
MEX
PIN
SCL
PHP
MIR
TFB
PEX
GIN
DOM
QMS
GRG
Evidence types
HSA
MMU
RNO
CFA
GGA
DRE
CIN
DME
CEL
BTA
SCE
ATH
SPO
BSU
ECO
PFA
DDI
SSO
SSC
MJA
OSA
Species
In Gold st.

ID Query gene
ID Query ortholog

Log-likelihood ratio (LLR)
	Highly positive
	Positive
	Zero
	Negative
	Highly negative
Known coupling
	This network
	Other network

2. ENSG00000130037
3. potassium voltage-gated…
- 2. KCNAB1
  3. potassium voltage-gated…
  4. 0.999
  5. PPI
- 2. KCNA4
  3. potassium voltage-gated…
  4. 0.998
  5. PPI
- 2. ACTN2
  3. actinin alpha 2
  4. 0.994
  5. PPI
- 2. KCNA2
  3. potassium voltage-gated…
  4. 0.975
  5. PPI
- 2. SRC
  3. SRC proto-oncogene, non…
  4. 0.968
  5. PPI
- 2. DLG1
  3. discs large MAGUK scaff…
  4. 0.905
  5. PPI
- 2. CAV1
  3. caveolin 1
  4. 0.889
  5. PPI
- 2. KCNA3
  3. potassium voltage-gated…
  4. 0.883
  5. PPI
- 2. KCNAB2
  3. potassium voltage-gated…
  4. 0.883
  5. PPI
- 2. DLG4
  3. discs large MAGUK scaff…
  4. 0.875
  5. PPI
- 2. KCNN2
  3. potassium calcium-activ…
  4. 0.843
  5. Metabolic
- 2. ACTN1
  3. actinin alpha 1
  4. 0.790
  5. PPI
- 2. SUMO1
  3. small ubiquitin like mo…
  4. 0.778
  5. PPI
- 2. PRKCB
  3. protein kinase C beta
  4. 0.771
  5. PPI
- 2. STUB1
  3. STIP1 homology and U-bo…
  4. 0.760
  5. PPI
- 2. ATP1A2
  3. ATPase Na+/K+ transport…
  4. 0.760
  5. Metabolic
- 2. DCTN2
  3. dynactin subunit 2
  4. 0.643
  5. PPI
- 2. FYN
  3. FYN proto-oncogene, Src…
  4. 0.637
  5. PPI
- 2. ATP2B4
  3. ATPase plasma membrane …
  4. 0.619
  5. PPI
- 2. KCNN1
  3. potassium calcium-activ…
  4. 0.506
  5. Metabolic
- 2. DPP10
  3. dipeptidyl peptidase li…
  4. 0.469
  5. Metabolic
- 2. ATP1A1
  3. ATPase Na+/K+ transport…
  4. 0.469
  5. Metabolic
- 2. CHRNA7
  3. cholinergic receptor ni…
  4. 0.458
  5. Metabolic
- 2. SCRIB
  3. scribble planar cell po…
  4. 0.412
  5. PPI

Subnetwork gene interactions

ENSG00000130037

potassium voltage-gated channel subfamily A member 5

FunCoup

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Ensembl

ENSG00000130037

UniProt

P22460

NCBI

3741

KCNAB2

potassium voltage-gated channel subfamily A regulatory beta subunit 2

FunCoup

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Ensembl

ENSG00000069424

UniProt

NCBI

8514

FYN

FYN proto-oncogene, Src family tyrosine kinase

FunCoup

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Ensembl

ENSG00000010810

UniProt

NCBI

2534

DLG1

discs large MAGUK scaffold protein 1

FunCoup

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Ensembl

ENSG00000075711

UniProt

NCBI

1739

DCTN2

dynactin subunit 2

FunCoup

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Ensembl

ENSG00000175203

UniProt

NCBI

10540

ATP1A1

ATPase Na+/K+ transporting subunit alpha 1

FunCoup

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Ensembl

ENSG00000163399

UniProt

NCBI

DPP10

dipeptidyl peptidase like 10

FunCoup

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Ensembl

ENSG00000175497

UniProt

NCBI

57628

KCNAB1

potassium voltage-gated channel subfamily A member regulatory beta subunit 1

FunCoup

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Ensembl

ENSG00000169282

UniProt

NCBI

7881

DLG4

discs large MAGUK scaffold protein 4

FunCoup

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Ensembl

ENSG00000132535

UniProt

NCBI

1742

KCNA3

potassium voltage-gated channel subfamily A member 3

FunCoup

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Ensembl

ENSG00000177272

UniProt

P22001

NCBI

3738

ACTN2

actinin alpha 2

FunCoup

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Ensembl

ENSG00000077522

UniProt

NCBI

KCNN2

potassium calcium-activated channel subfamily N member 2

FunCoup

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Ensembl

ENSG00000080709

UniProt

NCBI

3781

SRC

SRC proto-oncogene, non-receptor tyrosine kinase

FunCoup

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Ensembl

ENSG00000197122

UniProt

P12931

NCBI

6714

KCNA4

potassium voltage-gated channel subfamily A member 4

FunCoup

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Ensembl

ENSG00000182255

UniProt

P22459

NCBI

3739

KCNA2

potassium voltage-gated channel subfamily A member 2

FunCoup

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Ensembl

ENSG00000177301

UniProt

NCBI

3737

PRKCB

protein kinase C beta

FunCoup

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Ensembl

ENSG00000166501

UniProt

NCBI

5579

ACTN1

actinin alpha 1

FunCoup

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Ensembl

ENSG00000072110

UniProt

NCBI

SUMO1

small ubiquitin like modifier 1

FunCoup

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Ensembl

ENSG00000116030

UniProt

NCBI

7341

SCRIB

scribble planar cell polarity protein

FunCoup

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Ensembl

ENSG00000180900

UniProt

NCBI

23513

KCNN1

potassium calcium-activated channel subfamily N member 1

FunCoup

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Ensembl

ENSG00000105642

UniProt

NCBI

3780

STUB1

STIP1 homology and U-box containing protein 1

FunCoup

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Ensembl

ENSG00000103266

UniProt

NCBI

10273

CHRNA7

cholinergic receptor nicotinic alpha 7 subunit

FunCoup

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Ensembl

ENSG00000175344

UniProt

NCBI

1139
89832

ATP1A2

ATPase Na+/K+ transporting subunit alpha 2

FunCoup

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Ensembl

ENSG00000018625

UniProt

NCBI

ATP2B4

ATPase plasma membrane Ca2+ transporting 4

FunCoup

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Ensembl

ENSG00000058668

UniProt

NCBI

CAV1

caveolin 1

FunCoup

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Ensembl

ENSG00000105974

UniProt

NCBI

Query genes

		Identifier	Description
24	ENSG00000130037	ENSG00000130037	potassium voltage-gated channel subfamily A member 5
		UniProt	P22460
		NCBI	3741

Subnetwork genes

		Identifier	Description
11	KCNAB2	ENSG00000069424	potassium voltage-gated channel subfamily A regulatory beta subunit 2
		UniProt	A0A590UJ15 A0A590UJ35 A0A590UJ72 A0A590UJ79 A0A590UJB6 A0A590UJB8 A0A590UJI8 A0A590UJJ4 A0A590UJK5 A0A590UJU1 A0A590UJU4 A0A590UJV4 A0A590UJX9 A0A590UJY1 A0A590UK89 A0A5F9UN28 K7EIR5 K7EKU4 Q13303 Q5TG78 Q5TG81 Q5TG84
		NCBI	8514
9	FYN	ENSG00000010810	FYN proto-oncogene, Src family tyrosine kinase
		UniProt	E5RFM0 E5RFM4 E5RFM6 E5RFS5 E5RGM6 E5RGT0 E5RH71 E5RHF7 E5RHX7 E5RI25 E5RIX5 E5RJX7 E5RK23 P06241
		NCBI	2534
		KEGG signaling	Focal adhesion Fc epsilon RI signaling pathway Adherens junction Natural killer cell mediated cytotoxicity T cell receptor signaling pathway Phospholipase D signaling pathway Cholinergic synapse Sphingolipid signaling pathway
10	DLG1	ENSG00000075711	discs large MAGUK scaffold protein 1
		UniProt	A0A0C4DFT3 A0A590UJ08 A0A590UJ18 A0A590UJ25 A0A590UJ29 A0A590UJ64 A0A590UJ68 A0A590UJ81 A0A590UJ86 A0A590UJ95 A0A590UJC5 A0A590UJD9 A0A590UJE6 A0A590UJL2 A0A590UJR4 A0A590UJR5 A0A590UJS9 A0A590UJX2 A0A590UJZ4 A0A590UK02 A0A590UK13 A0A590UK31 A0A590UK48 A0A590UK52 A0A590UK70 A0A590UK81 A0A590UKA8 A8MUT6 B4E2H8 C9IYP1 C9J110 C9JCP6 C9JN61 C9JUA9 E7EQD7 F2Z2L0 H7C166 Q12959
		NCBI	1739
		KEGG signaling	Tight junction T cell receptor signaling pathway Hippo signaling pathway
7	DCTN2	ENSG00000175203	dynactin subunit 2
		UniProt	F8VRV7 F8VW18 F8VX93 F8W0U6 F8W1I6 H0YHL1 H0YI98 Q13561
		NCBI	10540
10	ATP1A1	ENSG00000163399	ATPase Na+/K+ transporting subunit alpha 1
		UniProt	P05023 Q5TC01 Q5TC02 Q5TC05
		NCBI	476
		KEGG signaling	cAMP signaling pathway Thyroid hormone signaling pathway cGMP-PKG signaling pathway Adrenergic signaling in cardiomyocytes Cardiac muscle contraction
		KEGG metabolic	Protein digestion and absorption Carbohydrate digestion and absorption
2	DPP10	ENSG00000175497	dipeptidyl peptidase like 10
		UniProt	C9J4M8 F8WEB2 J3KPP1 J3KQK8 Q8N608
		NCBI	57628
6	KCNAB1	ENSG00000169282	potassium voltage-gated channel subfamily A member regulatory beta subunit 1
		UniProt	A0A087X1P8 B7Z8E5 C9JBV8 C9JQ60 F8W6W4 H7C4S9 Q14722
		NCBI	7881
10	DLG4	ENSG00000132535	discs large MAGUK scaffold protein 4
		UniProt	A0A3B3IRP2 A0A3B3IS17 A0A3B3ISL1 A0A3B3ISQ5 A0A3B3ISR0 A0A3B3ITD1 A0A3B3ITI9 A0A3B3IU19 B7Z3U2 B7Z647 B9EGL1 C9JWP9 C9JYG3 K7EKP9 K7EKU8 O14909 P78352
		NCBI	1742
		KEGG signaling	Hippo signaling pathway Glutamatergic synapse
10	KCNA3	ENSG00000177272	potassium voltage-gated channel subfamily A member 3
		UniProt	P22001
		NCBI	3738
5	ACTN2	ENSG00000077522	actinin alpha 2
		UniProt	A0A494C031 A0A494C033 A0A494C060 A0A494C0Q3 A0A494C166 A0A494C1A0 F6THM6 P35609
		NCBI	88
7	KCNN2	ENSG00000080709	potassium calcium-activated channel subfamily N member 2
		UniProt	A0A0J9YW81 A0A3F2YNY5 D6RGY7 Q9H2S1
		NCBI	3781
		KEGG signaling	Serotonergic synapse
11	SRC	ENSG00000197122	SRC proto-oncogene, non-receptor tyrosine kinase
		UniProt	P12931
		NCBI	6714
		KEGG signaling	Thyroid hormone signaling pathway Chemokine signaling pathway VEGF signaling pathway Rap1 signaling pathway Focal adhesion Adherens junction Tight junction Gap junction ErbB signaling pathway Prolactin signaling pathway Relaxin signaling pathway Estrogen signaling pathway GABAergic synapse GnRH signaling pathway C-type lectin receptor signaling pathway Oxytocin signaling pathway
		KEGG metabolic	Endocytosis
12	KCNA4	ENSG00000182255	potassium voltage-gated channel subfamily A member 4
		UniProt	P22459
		NCBI	3739
9	KCNA2	ENSG00000177301	potassium voltage-gated channel subfamily A member 2
		UniProt	A0A1W2PP65 A0A1W2PPM7 A0A1W2PPN8 A0A1W2PR01 A0A1W2PRY2 P16389
		NCBI	3737
8	PRKCB	ENSG00000166501	protein kinase C beta
		UniProt	H3BV73 I3L148 I3L1Z0 P05771
		NCBI	5579
		KEGG signaling	Thyroid hormone signaling pathway Calcium signaling pathway NF-kappa B signaling pathway Chemokine signaling pathway Fc gamma R-mediated phagocytosis Long-term potentiation B cell receptor signaling pathway Gap junction HIF-1 signaling pathway Dopaminergic synapse GABAergic synapse Serotonergic synapse Cholinergic synapse Glutamatergic synapse Oxytocin signaling pathway Retrograde endocannabinoid signaling Leukocyte transendothelial migration MAPK signaling pathway VEGF signaling pathway mTOR signaling pathway Vascular smooth muscle contraction Sphingolipid signaling pathway Phosphatidylinositol signaling system Rap1 signaling pathway Long-term depression Focal adhesion Ras signaling pathway Wnt signaling pathway ErbB signaling pathway Natural killer cell mediated cytotoxicity Melanogenesis GnRH signaling pathway
		KEGG metabolic	Carbohydrate digestion and absorption
12	ACTN1	ENSG00000072110	actinin alpha 1
		UniProt	G3V2E8 G3V2N5 G3V2W4 G3V2X9 G3V380 G3V5M4 H0YJ11 H0YJW3 H7C5W8 H9KV75 P12814
		NCBI	87
		KEGG signaling	Focal adhesion Adherens junction Tight junction Leukocyte transendothelial migration
4	SUMO1	ENSG00000116030	small ubiquitin like modifier 1
		UniProt	B8ZZ67 B8ZZJ0 B8ZZN6 B9A032 F8WBI1 P63165
		NCBI	7341
		KEGG metabolic	RNA transport
7	SCRIB	ENSG00000180900	scribble planar cell polarity protein
		UniProt	H0YCG0 H0YDF9 Q14160
		NCBI	23513
		KEGG signaling	Tight junction Hippo signaling pathway
8	KCNN1	ENSG00000105642	potassium calcium-activated channel subfamily N member 1
		UniProt	A0A087X2E7 Q92952 V9GYV2
		NCBI	3780
5	STUB1	ENSG00000103266	STIP1 homology and U-box containing protein 1
		UniProt	H3BS86 H3BTA3 H3BUD0 Q9UNE7 V9GYH3
		NCBI	10273
		KEGG metabolic	Ubiquitin mediated proteolysis Protein processing in endoplasmic reticulum
8	CHRNA7	ENSG00000175344	cholinergic receptor nicotinic alpha 7 subunit
		UniProt	A0A1B0GTE0 A0A1B0GTT0 A0A1B0GTT9 A0A1B0GU04 A0A1B0GU11 A0A1B0GU56 A0A1B0GU93 A0A1B0GUR5 A0A1B0GV25 A0A1B0GV43 A0A1B0GV44 A0A1B0GV86 A0A1B0GVH2 A0A1B0GVI5 A0A1B0GVN6 A0A1B0GVP9 A0A1B0GW47 A0A1B0GW52 A0A1B0GWH1 P36544
		NCBI	1139 89832
		KEGG signaling	Calcium signaling pathway Cholinergic synapse Neuroactive ligand-receptor interaction
6	ATP1A2	ENSG00000018625	ATPase Na+/K+ transporting subunit alpha 2
		UniProt	B1AKY9 H0Y7C1 P50993
		NCBI	477
		KEGG signaling	cAMP signaling pathway Thyroid hormone signaling pathway cGMP-PKG signaling pathway Adrenergic signaling in cardiomyocytes Cardiac muscle contraction
		KEGG metabolic	Protein digestion and absorption Carbohydrate digestion and absorption
3	ATP2B4	ENSG00000058668	ATPase plasma membrane Ca2+ transporting 4
		UniProt	H0YDG5 H7BY13 H7BZS8 P23634
		NCBI	493
		KEGG signaling	cAMP signaling pathway cGMP-PKG signaling pathway Calcium signaling pathway Adrenergic signaling in cardiomyocytes
6	CAV1	ENSG00000105974	caveolin 1
		UniProt	C9JKI3 E9PCT5 F8WDM7 Q03135
		NCBI	857
		KEGG signaling	Focal adhesion
		KEGG metabolic	Endocytosis

Enrichment analysis

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	jSquid_subnetworks.xml	202.58 KB
	H.sapiens_subnetwork.tsv	16.73 KB

Species:

Network information:

Filter Results:

Network appearance:

ENSG00000130037

KCNAB2

FYN

DLG1

DCTN2

ATP1A1

DPP10

KCNAB1

DLG4

KCNA3

ACTN2

KCNN2

SRC

KCNA4

KCNA2

PRKCB

ACTN1

SUMO1

SCRIB

KCNN1

STUB1

CHRNA7

ATP1A2

ATP2B4

CAV1

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