Found 1 of 1 query genes

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Query interactions

Interaction partners
Confidence
Network
MEX
PIN
SCL
PHP
MIR
TFB
PEX
GIN
DOM
QMS
GRG
Evidence types
HSA
MMU
RNO
CFA
GGA
DRE
CIN
DME
CEL
BTA
SCE
ATH
SPO
BSU
ECO
PFA
DDI
SSO
SSC
MJA
OSA
Species
In Gold st.

ID Query gene
ID Query ortholog

Log-likelihood ratio (LLR)
	Highly positive
	Positive
	Zero
	Negative
	Highly negative
Known coupling
	This network
	Other network

2. ENSG00000129691
3. ASH2 like, histone lysi…
- 2. WDR5
  3. WD repeat domain 5
  4. 1.000
  5. PPI
- 2. RBBP5
  3. RB binding protein 5, h…
  4. 1.000
  5. PPI
- 2. DPY30
  3. dpy-30 histone methyltr…
  4. 1.000
  5. PPI
- 2. PAXIP1
  3. PAX interacting protein…
  4. 1.000
  5. PPI
- 2. SETD1B
  3. SET domain containing 1…
  4. 1.000
  5. PPI
- 2. KDM6A
  3. lysine demethylase 6A
  4. 1.000
  5. Complex
- 2. KMT2C
  3. lysine methyltransferas…
  4. 1.000
  5. PPI
- 2. MEN1
  3. menin 1
  4. 1.000
  5. PPI
- 2. RNF2
  3. ring finger protein 2
  4. 1.000
  5. PPI
- 2. KMT2D
  3. lysine methyltransferas…
  4. 1.000
  5. PPI
- 2. SIN3A
  3. SIN3 transcription regu…
  4. 1.000
  5. PPI
- 2. KMT2A
  3. lysine methyltransferas…
  4. 1.000
  5. PPI
- 2. SETD1A
  3. SET domain containing 1…
  4. 1.000
  5. PPI
- 2. E2F4
  3. E2F transcription facto…
  4. 1.000
  5. PPI
- 2. HCFC2
  3. host cell factor C2
  4. 1.000
  5. PPI
- 2. KMT2B
  3. lysine methyltransferas…
  4. 1.000
  5. PPI
- 2. CXXC1
  3. CXXC finger protein 1
  4. 1.000
  5. PPI
- 2. KDM6B
  3. lysine demethylase 6B
  4. 1.000
  5. PPI
- 2. KAT8
  3. lysine acetyltransferas…
  4. 0.999
  5. PPI
- 2. CHD8
  3. chromodomain helicase D…
  4. 0.999
  5. PPI
- 2. SP1
  3. Sp1 transcription factor
  4. 0.999
  5. PPI
- 2. PAGR1
  3. PAXIP1 associated gluta…
  4. 0.999
  5. PPI
- 2. WDR82
  3. WD repeat domain 82
  4. 0.999
  5. PPI
- 2. MRE11
  3. MRE11 homolog, double s…
  4. 0.999
  5. Complex
- 2. NCOA6
  3. nuclear receptor coacti…
  4. 0.999
  5. PPI
- 2. ASXL1
  3. ASXL transcriptional re…
  4. 0.999
  5. Complex
- 2. KDM4B
  3. lysine demethylase 4B
  4. 0.998
  5. PPI
- 2. EP300
  3. E1A binding protein p300
  4. 0.998
  5. PPI
- 2. HCFC1
  3. host cell factor C1
  4. 0.998
  5. PPI
- 2. WDR5B
  3. WD repeat domain 5B
  4. 0.998
  5. PPI

Subnetwork gene interactions

ENSG00000129691

ASH2 like, histone lysine methyltransferase complex subunit

FunCoup

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Ensembl

ENSG00000129691

UniProt

NCBI

9070

CXXC1

CXXC finger protein 1

FunCoup

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Ensembl

ENSG00000154832

UniProt

NCBI

30827

DPY30

dpy-30 histone methyltransferase complex regulatory subunit

FunCoup

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Ensembl

ENSG00000162961

UniProt

Q9C005

NCBI

84661

SETD1B

SET domain containing 1B, histone lysine methyltransferase

FunCoup

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Ensembl

ENSG00000139718

UniProt

NCBI

23067

WDR5

WD repeat domain 5

FunCoup

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Ensembl

ENSG00000196363

UniProt

NCBI

11091

KAT8

lysine acetyltransferase 8

FunCoup

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Ensembl

ENSG00000103510

UniProt

NCBI

84148

HCFC1

host cell factor C1

FunCoup

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Ensembl

ENSG00000172534

UniProt

NCBI

3054

NCOA6

nuclear receptor coactivator 6

FunCoup

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Ensembl

ENSG00000198646

UniProt

NCBI

23054

KMT2D

lysine methyltransferase 2D

FunCoup

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Ensembl

ENSG00000167548

UniProt

NCBI

8085

WDR82

WD repeat domain 82

FunCoup

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Ensembl

ENSG00000164091

UniProt

NCBI

80335

KMT2B

lysine methyltransferase 2B

FunCoup

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Ensembl

ENSG00000272333

UniProt

Q9UMN6

NCBI

9757

PAGR1

PAXIP1 associated glutamate rich protein 1

FunCoup

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Ensembl

ENSG00000280789

UniProt

Q9BTK6

NCBI

79447

EP300

E1A binding protein p300

FunCoup

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Ensembl

ENSG00000100393

UniProt

NCBI

2033

SIN3A

SIN3 transcription regulator family member A

FunCoup

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Ensembl

ENSG00000169375

UniProt

NCBI

25942

E2F4

E2F transcription factor 4

FunCoup

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Ensembl

ENSG00000205250

UniProt

NCBI

1874

KDM6A

lysine demethylase 6A

FunCoup

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Ensembl

ENSG00000147050

UniProt

NCBI

7403

KMT2A

lysine methyltransferase 2A

FunCoup

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Ensembl

ENSG00000118058

UniProt

NCBI

4297

SETD1A

SET domain containing 1A, histone lysine methyltransferase

FunCoup

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Ensembl

ENSG00000099381

UniProt

NCBI

9739

KDM4B

lysine demethylase 4B

FunCoup

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Ensembl

ENSG00000127663

UniProt

NCBI

23030

ASXL1

ASXL transcriptional regulator 1

FunCoup

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Ensembl

ENSG00000171456

UniProt

NCBI

171023

WDR5B

WD repeat domain 5B

FunCoup

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Ensembl

ENSG00000196981

UniProt

Q86VZ2

NCBI

54554

CHD8

chromodomain helicase DNA binding protein 8

FunCoup

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Ensembl

ENSG00000100888

UniProt

NCBI

57680

KMT2C

lysine methyltransferase 2C

FunCoup

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Ensembl

ENSG00000055609

UniProt

NCBI

58508

PAXIP1

PAX interacting protein 1

FunCoup

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Ensembl

ENSG00000157212

UniProt

NCBI

22976

MEN1

menin 1

FunCoup

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Ensembl

ENSG00000133895

UniProt

NCBI

4221

RBBP5

RB binding protein 5, histone lysine methyltransferase complex subunit

FunCoup

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Ensembl

ENSG00000117222

UniProt

Q15291

NCBI

5929

RNF2

ring finger protein 2

FunCoup

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Ensembl

ENSG00000121481

UniProt

NCBI

6045

KDM6B

lysine demethylase 6B

FunCoup

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Ensembl

ENSG00000132510

UniProt

NCBI

23135

HCFC2

host cell factor C2

FunCoup

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Ensembl

ENSG00000111727

UniProt

NCBI

29915

SP1

Sp1 transcription factor

FunCoup

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Ensembl

ENSG00000185591

UniProt

NCBI

6667

MRE11

MRE11 homolog, double strand break repair nuclease

FunCoup

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Ensembl

ENSG00000020922

UniProt

NCBI

4361

Query genes

		Identifier	Description
30	ENSG00000129691	ENSG00000129691	ASH2 like, histone lysine methyltransferase complex subunit
		UniProt	E5RFH5 E5RHM1 F5H8F7 H0YAQ0 H0YBF6 Q9UBL3
		NCBI	9070

Subnetwork genes

		Identifier	Description
16	CXXC1	ENSG00000154832	CXXC finger protein 1
		UniProt	K7EJR0 K7EKZ6 K7EQ21 K7EQZ1 Q9P0U4
		NCBI	30827
20	DPY30	ENSG00000162961	dpy-30 histone methyltransferase complex regulatory subunit
		UniProt	Q9C005
		NCBI	84661
17	SETD1B	ENSG00000139718	SET domain containing 1B, histone lysine methyltransferase
		UniProt	A0A0A0MQV9 Q9UPS6
		NCBI	23067
28	WDR5	ENSG00000196363	WD repeat domain 5
		UniProt	P61964 V9GYQ5 V9GZ59
		NCBI	11091
16	KAT8	ENSG00000103510	lysine acetyltransferase 8
		UniProt	A0A494C0I2 H3BMX5 Q9H7Z6
		NCBI	84148
22	HCFC1	ENSG00000172534	host cell factor C1
		UniProt	A6NEM2 H7C1C4 P51610
		NCBI	3054
16	NCOA6	ENSG00000198646	nuclear receptor coactivator 6
		UniProt	A0A0D9SFT8 F6M2K2 F6M2K4 Q14686
		NCBI	23054
21	KMT2D	ENSG00000167548	lysine methyltransferase 2D
		UniProt	A0A3B3ISC8 F8VWW4 H0YEF2 O14686
		NCBI	8085
		KEGG metabolic	Lysine degradation
21	WDR82	ENSG00000164091	WD repeat domain 82
		UniProt	C9J355 C9JBU3 Q6UXN9
		NCBI	80335
		KEGG metabolic	mRNA surveillance pathway
18	KMT2B	ENSG00000272333	lysine methyltransferase 2B
		UniProt	Q9UMN6
		NCBI	9757
		KEGG metabolic	Lysine degradation
13	PAGR1	ENSG00000280789	PAXIP1 associated glutamate rich protein 1
		UniProt	Q9BTK6
		NCBI	79447
16	EP300	ENSG00000100393	E1A binding protein p300
		UniProt	A0A0U1RQG3 A0A0U1RR87 Q09472
		NCBI	2033
		KEGG signaling	Thyroid hormone signaling pathway TGF-beta signaling pathway Long-term potentiation Adherens junction JAK-STAT signaling pathway cAMP signaling pathway Wnt signaling pathway FoxO signaling pathway Cell cycle HIF-1 signaling pathway Notch signaling pathway Melanogenesis Glucagon signaling pathway
22	SIN3A	ENSG00000169375	SIN3 transcription regulator family member A
		UniProt	H3BMA2 H3BNA0 H3BNZ3 H3BP90 H3BQ76 H3BQ88 H3BQL7 H3BT34 Q96ST3
		NCBI	25942
		KEGG signaling	Thyroid hormone signaling pathway
10	E2F4	ENSG00000205250	E2F transcription factor 4
		UniProt	H3BMP3 H3BTM3 H3BVE4 I3L1B6 Q16254
		NCBI	1874
		KEGG signaling	Cell cycle TGF-beta signaling pathway
23	KDM6A	ENSG00000147050	lysine demethylase 6A
		UniProt	A0A087WUN6 A0A087X0R0 F5H5V6 F5H6S1 F8W8R6 H0Y5J3 H0Y6I7 H0Y6V5 H7C1F1 O15550
		NCBI	7403
21	KMT2A	ENSG00000118058	lysine methyltransferase 2A
		UniProt	A0A3B3ISN4 A0A3B3ITT0 A0A3B3ITT7 A0A3B3ITZ6 E9PR05 H0YEU4 H7C5V8 H7C5W4 Q03164
		NCBI	4297
		KEGG metabolic	Lysine degradation
28	SETD1A	ENSG00000099381	SET domain containing 1A, histone lysine methyltransferase
		UniProt	C9J2Z9 O15047
		NCBI	9739
		KEGG metabolic	Lysine degradation
9	KDM4B	ENSG00000127663	lysine demethylase 4B
		UniProt	A0A0C4DFL8 F5GX28 K7EQ54 K7ES23 O94953
		NCBI	23030
10	ASXL1	ENSG00000171456	ASXL transcriptional regulator 1
		UniProt	A0A087WWN0 A0A2R8Y4U9 A0A2R8Y5U1 A0A2R8Y627 A0A2R8Y6F0 A0A2R8Y6V0 A0A494C1R1 H0YJC9 Q498B9 Q5JWS8 Q6P1M8 Q76L82 Q8IXJ9
		NCBI	171023
7	WDR5B	ENSG00000196981	WD repeat domain 5B
		UniProt	Q86VZ2
		NCBI	54554
13	CHD8	ENSG00000100888	chromodomain helicase DNA binding protein 8
		UniProt	A0A2R8Y4P3 A0A2R8Y808 A0A2R8Y840 A0A2R8YFI9 A0A2R8YFT4 G3V2T9 G3V303 H0YJA4 H0YJG4 Q9HCK8
		NCBI	57680
		KEGG signaling	Wnt signaling pathway
17	KMT2C	ENSG00000055609	lysine methyltransferase 2C
		UniProt	C9J4Z5 H0Y765 H0YMU7 H0YNL4 H7BY37 H7C212 H7C2V8 Q8NEZ4
		NCBI	58508
		KEGG metabolic	Lysine degradation
18	PAXIP1	ENSG00000157212	PAX interacting protein 1
		UniProt	F8WC23 H7BZI8 Q6ZW49
		NCBI	22976
20	MEN1	ENSG00000133895	menin 1
		UniProt	A0A5F9ZHS3 A0A5F9ZI68 E7EN32 E7ENS2 O00255 Q9GZQ5
		NCBI	4221
27	RBBP5	ENSG00000117222	RB binding protein 5, histone lysine methyltransferase complex subunit
		UniProt	Q15291
		NCBI	5929
19	RNF2	ENSG00000121481	ring finger protein 2
		UniProt	Q99496 X6RFN3
		NCBI	6045
6	KDM6B	ENSG00000132510	lysine demethylase 6B
		UniProt	I3L0Z0 O15054
		NCBI	23135
16	HCFC2	ENSG00000111727	host cell factor C2
		UniProt	F8VU09 Q9Y5Z7
		NCBI	29915
7	SP1	ENSG00000185591	Sp1 transcription factor
		UniProt	H3BUU5 H3BVI2 P08047
		NCBI	6667
		KEGG signaling	TGF-beta signaling pathway Estrogen signaling pathway
9	MRE11	ENSG00000020922	MRE11 homolog, double strand break repair nuclease
		UniProt	F5GXT0 F5H256 F5H742 F8W7U8 P49959
		NCBI	4361
		KEGG metabolic	Non-homologous end-joining Homologous recombination

Enrichment analysis

Search for enrichment of pathways or functional gene sets for your subnetwork genes

To use PathwAX, first use the button below to copy the subnetwork genes and then paste them in PathwAX

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	jSquid_subnetworks.xml	278.55 KB
	H.sapiens_subnetwork.tsv	36.47 KB

Species:

Network information:

Filter Results:

Network appearance:

ENSG00000129691

CXXC1

DPY30

SETD1B

WDR5

KAT8

HCFC1

NCOA6

KMT2D

WDR82

KMT2B

PAGR1

EP300

SIN3A

E2F4

KDM6A

KMT2A

SETD1A

KDM4B

ASXL1

WDR5B

CHD8

KMT2C

PAXIP1

MEN1

RBBP5

RNF2

KDM6B

HCFC2

SP1

MRE11

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