Found 1 of 1 query genes

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Query interactions

Interaction partners
Confidence
Network
MEX
PIN
SCL
PHP
MIR
TFB
PEX
GIN
DOM
QMS
GRG
Evidence types
HSA
MMU
RNO
CFA
GGA
DRE
CIN
DME
CEL
BTA
SCE
ATH
SPO
BSU
ECO
PFA
DDI
SSO
SSC
MJA
OSA
Species
In Gold st.

ID Query gene
ID Query ortholog

Log-likelihood ratio (LLR)
	Highly positive
	Positive
	Zero
	Negative
	Highly negative
Known coupling
	This network
	Other network

2. ENSG00000116560
3. splicing factor proline…
- 2. HSPA8
  3. heat shock protein fami…
  4. 1.000
  5. Complex
- 2. PTBP1
  3. polypyrimidine tract bi…
  4. 1.000
  5. PPI
- 2. EEF1A1
  3. eukaryotic translation …
  4. 1.000
  5. Complex
- 2. NONO
  3. non-POU domain containi…
  4. 1.000
  5. PPI
- 2. EED
  3. embryonic ectoderm deve…
  4. 1.000
  5. Complex
- 2. HNRNPA1
  3. heterogeneous nuclear r…
  4. 1.000
  5. PPI
- 2. DDX39B
  3. DExD-box helicase 39B
  4. 1.000
  5. PPI
- 2. TUBB
  3. tubulin beta class I
  4. 1.000
  5. Complex
- 2. PSPC1
  3. paraspeckle component 1
  4. 1.000
  5. PPI
- 2. NCL
  3. nucleolin
  4. 1.000
  5. PPI
- 2. HNRNPAB
  3. heterogeneous nuclear r…
  4. 1.000
  5. PPI
- 2. KHDRBS1
  3. KH RNA binding domain c…
  4. 1.000
  5. PPI
- 2. CCT8
  3. chaperonin containing T…
  4. 1.000
  5. Complex
- 2. YWHAZ
  3. tyrosine 3-monooxygenas…
  4. 1.000
  5. Complex
- 2. YWHAE
  3. tyrosine 3-monooxygenas…
  4. 1.000
  5. Complex
- 2. ILF2
  3. interleukin enhancer bi…
  4. 1.000
  5. Complex
- 2. CCT4
  3. chaperonin containing T…
  4. 1.000
  5. Complex
- 2. PABPC1
  3. poly(A) binding protein…
  4. 1.000
  5. Complex
- 2. TUBA1B
  3. tubulin alpha 1b
  4. 1.000
  5. Complex
- 2. HNRNPD
  3. heterogeneous nuclear r…
  4. 0.999
  5. Metabolic
- 2. MATR3
  3. matrin 3
  4. 0.999
  5. PPI
- 2. HSP90AB1
  3. heat shock protein 90 a…
  4. 0.999
  5. PPI
- 2. PRMT1
  3. protein arginine methyl…
  4. 0.999
  5. PPI
- 2. DDX5
  3. DEAD-box helicase 5
  4. 0.999
  5. Complex
- 2. SREK1
  3. splicing regulatory glu…
  4. 0.999
  5. PPI
- 2. TIAL1
  3. TIA1 cytotoxic granule …
  4. 0.999
  5. PPI
- 2. ELAVL1
  3. ELAV like RNA binding p…
  4. 0.999
  5. PPI
- 2. VIM
  3. vimentin
  4. 0.999
  5. Complex
- 2. SNRPA
  3. small nuclear ribonucle…
  4. 0.999
  5. PPI
- 2. RUVBL2
  3. RuvB like AAA ATPase 2
  4. 0.998
  5. PPI

Subnetwork gene interactions

ENSG00000116560

splicing factor proline and glutamine rich

FunCoup

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Ensembl

ENSG00000116560

UniProt

NCBI

6421

PSPC1

paraspeckle component 1

FunCoup

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Ensembl

ENSG00000121390

UniProt

NCBI

55269

ELAVL1

ELAV like RNA binding protein 1

FunCoup

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Ensembl

ENSG00000066044

UniProt

NCBI

1994

DDX39B

DExD-box helicase 39B

FunCoup

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Ensembl

ENSG00000198563

UniProt

NCBI

7919

DDX5

DEAD-box helicase 5

FunCoup

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Ensembl

ENSG00000108654

UniProt

NCBI

1655

HNRNPA1

heterogeneous nuclear ribonucleoprotein A1

FunCoup

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Ensembl

ENSG00000135486

UniProt

NCBI

3178

SNRPA

small nuclear ribonucleoprotein polypeptide A

FunCoup

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Ensembl

ENSG00000077312

UniProt

NCBI

6626

HSPA8

heat shock protein family A (Hsp70) member 8

FunCoup

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Ensembl

ENSG00000109971

UniProt

NCBI

3312

CCT4

chaperonin containing TCP1 subunit 4

FunCoup

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Ensembl

ENSG00000115484

UniProt

P50991

NCBI

10575

TUBB

tubulin beta class I

FunCoup

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Ensembl

ENSG00000196230

UniProt

NCBI

203068

PTBP1

polypyrimidine tract binding protein 1

FunCoup

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Ensembl

ENSG00000011304

UniProt

NCBI

5725

HNRNPAB

heterogeneous nuclear ribonucleoprotein A/B

FunCoup

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Ensembl

ENSG00000197451

UniProt

NCBI

3182

KHDRBS1

KH RNA binding domain containing, signal transduction associated 1

FunCoup

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Ensembl

ENSG00000121774

UniProt

Q07666

NCBI

10657

ILF2

interleukin enhancer binding factor 2

FunCoup

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Ensembl

ENSG00000143621

UniProt

NCBI

3608

EEF1A1

eukaryotic translation elongation factor 1 alpha 1

FunCoup

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Ensembl

ENSG00000156508

UniProt

NCBI

1915

HNRNPD

heterogeneous nuclear ribonucleoprotein D

FunCoup

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Ensembl

ENSG00000138668

UniProt

NCBI

3184

SREK1

splicing regulatory glutamic acid and lysine rich protein 1

FunCoup

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Ensembl

ENSG00000153914

UniProt

NCBI

140890

NCL

nucleolin

FunCoup

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Ensembl

ENSG00000115053

UniProt

NCBI

4691

TIAL1

TIA1 cytotoxic granule associated RNA binding protein like 1

FunCoup

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Ensembl

ENSG00000151923

UniProt

NCBI

7073

PRMT1

protein arginine methyltransferase 1

FunCoup

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Ensembl

ENSG00000126457

UniProt

NCBI

3276

MATR3

matrin 3

FunCoup

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Ensembl

ENSG00000015479

UniProt

NCBI

9782

RUVBL2

RuvB like AAA ATPase 2

FunCoup

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Ensembl

ENSG00000183207

UniProt

NCBI

10856

EED

embryonic ectoderm development

FunCoup

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Ensembl

ENSG00000074266

UniProt

NCBI

8726

NONO

non-POU domain containing octamer binding

FunCoup

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Ensembl

ENSG00000147140

UniProt

NCBI

4841

PABPC1

poly(A) binding protein cytoplasmic 1

FunCoup

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Ensembl

ENSG00000070756

UniProt

NCBI

26986

TUBA1B

tubulin alpha 1b

FunCoup

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Ensembl

ENSG00000123416

UniProt

NCBI

10376

YWHAZ

tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein zeta

FunCoup

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Ensembl

ENSG00000164924

UniProt

NCBI

7534

HSP90AB1

heat shock protein 90 alpha family class B member 1

FunCoup

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Ensembl

ENSG00000096384

UniProt

P08238

NCBI

3326

VIM

vimentin

FunCoup

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Ensembl

ENSG00000026025

UniProt

NCBI

7431

CCT8

chaperonin containing TCP1 subunit 8

FunCoup

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Ensembl

ENSG00000156261

UniProt

NCBI

10694

YWHAE

tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein epsilon

FunCoup

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Ensembl

ENSG00000108953

UniProt

NCBI

7531

Query genes

		Identifier	Description
30	ENSG00000116560	ENSG00000116560	splicing factor proline and glutamine rich
		UniProt	H0Y9K7 H0Y9U2 P23246
		NCBI	6421

Subnetwork genes

		Identifier	Description
25	PSPC1	ENSG00000121390	paraspeckle component 1
		UniProt	A0A0U1RQF9 Q8WXF1 X6RDA4
		NCBI	55269
26	ELAVL1	ENSG00000066044	ELAV like RNA binding protein 1
		UniProt	M0QZR9 M0R055 Q15717
		NCBI	1994
		KEGG signaling	AMPK signaling pathway IL-17 signaling pathway
28	DDX39B	ENSG00000198563	DExD-box helicase 39B
		UniProt	A0A0A0MT12 F6QYI9 F6R6M7 F6S2B7 F6S4E6 F6SXL5 F6TRA5 F6U6E2 F6UJC5 F6WLT2 H0Y400 H0YCC6 Q13838 Q5STU3
		NCBI	7919
		KEGG metabolic	Spliceosome RNA transport mRNA surveillance pathway
29	DDX5	ENSG00000108654	DEAD-box helicase 5
		UniProt	A0A0G2JLI4 J3KRX8 J3KRZ1 J3KTA4 J3KTQ4 J3QKN9 J3QLG9 J3QR02 J3QR62 J3QRN5 J3QRQ7 J3QS79 J3QS97 J3QSF1 K7EKV0 P17844 X6RLV5
		NCBI	1655
		KEGG metabolic	Spliceosome
28	HNRNPA1	ENSG00000135486	heterogeneous nuclear ribonucleoprotein A1
		UniProt	F8VTQ5 F8VYN5 F8VZ49 F8W646 F8W6I7 H0YH80 P09651
		NCBI	3178
		KEGG metabolic	Spliceosome
21	SNRPA	ENSG00000077312	small nuclear ribonucleoprotein polypeptide A
		UniProt	M0QXK2 M0QZG7 M0R0G9 M0R221 M0R268 M0R2B8 P09012
		NCBI	6626
		KEGG metabolic	Spliceosome
29	HSPA8	ENSG00000109971	heat shock protein family A (Hsp70) member 8
		UniProt	A8K7Q2 E9PI65 E9PK54 E9PKE3 E9PLF4 E9PM13 E9PN25 E9PN89 E9PNE6 E9PPY6 E9PQK7 E9PQQ4 E9PS65 P11142
		NCBI	3312
		KEGG signaling	Antigen processing and presentation MAPK signaling pathway Estrogen signaling pathway
		KEGG metabolic	Spliceosome Endocytosis Protein processing in endoplasmic reticulum
28	CCT4	ENSG00000115484	chaperonin containing TCP1 subunit 4
		UniProt	P50991
		NCBI	10575
29	TUBB	ENSG00000196230	tubulin beta class I
		UniProt	P07437 Q5JP53 Q5ST81
		NCBI	203068
		KEGG signaling	Gap junction
		KEGG metabolic	Phagosome
28	PTBP1	ENSG00000011304	polypyrimidine tract binding protein 1
		UniProt	A0A087WTS6 A0A087WU68 A0A087WUW5 A0A0D9SF20 A0A0U1RRM4 A6NLN1 K7EK45 K7EKJ7 K7EKX4 K7ELW5 K7ES59 P26599
		NCBI	5725
28	HNRNPAB	ENSG00000197451	heterogeneous nuclear ribonucleoprotein A/B
		UniProt	D6R9P3 D6RBZ0 D6RD18 Q99729
		NCBI	3182
22	KHDRBS1	ENSG00000121774	KH RNA binding domain containing, signal transduction associated 1
		UniProt	Q07666
		NCBI	10657
27	ILF2	ENSG00000143621	interleukin enhancer binding factor 2
		UniProt	A0A0A0MRL0 B4DY09 Q12905 X6R6Z1
		NCBI	3608
29	EEF1A1	ENSG00000156508	eukaryotic translation elongation factor 1 alpha 1
		UniProt	A0A087WV01 A0A087WVQ9 A6PW80 P68104 Q5JR01
		NCBI	1915
		KEGG metabolic	RNA transport
23	HNRNPD	ENSG00000138668	heterogeneous nuclear ribonucleoprotein D
		UniProt	D6RAF8 D6RBP9 D6RBQ9 D6RD83 D6RF44 H0Y8G5 H0YA96 Q14103
		NCBI	3184
13	SREK1	ENSG00000153914	splicing regulatory glutamic acid and lysine rich protein 1
		UniProt	A0A087WY03 E5RFV3 E5RJ76 E5RK30 H0YC47 Q8WXA9
		NCBI	140890
30	NCL	ENSG00000115053	nucleolin
		UniProt	C9J1H7 C9JLB1 C9JWL1 C9JYW2 H7BY16 P19338
		NCBI	4691
24	TIAL1	ENSG00000151923	TIA1 cytotoxic granule associated RNA binding protein like 1
		UniProt	A0A087WX93 A6NKZ9 E7ETC0 E7ETJ9 Q01085
		NCBI	7073
25	PRMT1	ENSG00000126457	protein arginine methyltransferase 1
		UniProt	E9PIE2 E9PIX6 E9PKG1 E9PMW9 E9PMZ2 E9PNR9 E9PQ98 H0YDE4 Q99873
		NCBI	3276
		KEGG signaling	FoxO signaling pathway Glucagon signaling pathway
14	MATR3	ENSG00000015479	matrin 3
		UniProt	A0A1B0GX04 B3KM87 D6R991 D6R9F3 D6RAY2 D6RBI2 D6RBK5 D6RBS2 D6RE02 D6REK4 D6REM6 D6RIA2 H0Y8T4 P43243 Q68E03
		NCBI	9782
24	RUVBL2	ENSG00000183207	RuvB like AAA ATPase 2
		UniProt	A0A1W2PS22 A0A1W2PS48 M0QXI6 M0QXZ7 M0QYD8 M0R0Y3 M0R0Z0 Q9Y230 X6R2L4
		NCBI	10856
27	EED	ENSG00000074266	embryonic ectoderm development
		UniProt	A0A5F9ZI63 E9PJK2 E9PMU3 H0YEL4 O75530
		NCBI	8726
27	NONO	ENSG00000147140	non-POU domain containing octamer binding
		UniProt	C9IZL7 C9J4X2 C9JJ13 C9JYS8 H7C367 Q15233
		NCBI	4841
26	PABPC1	ENSG00000070756	poly(A) binding protein cytoplasmic 1
		UniProt	A0A087WTT1 E5RFD8 E5RGC4 E5RGH3 E5RH24 E5RHG7 E5RJB9 E5RJM8 E7EQV3 E7ERJ7 H0YAP2 H0YAR2 H0YAS6 H0YAS7 H0YAW6 H0YB75 H0YB86 H0YBN4 H0YC10 P11940
		NCBI	26986
		KEGG metabolic	RNA degradation RNA transport mRNA surveillance pathway
25	TUBA1B	ENSG00000123416	tubulin alpha 1b
		UniProt	F8VRK0 F8VU66 F8VVB9 F8VWV9 F8VX09 P68363
		NCBI	10376
		KEGG signaling	Tight junction Apoptosis Gap junction
		KEGG metabolic	Phagosome
23	YWHAZ	ENSG00000164924	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein zeta
		UniProt	B0AZS6 B7Z2E6 E5RGE1 E5RIR4 E7ESK7 E7EVZ2 E7EX29 E9PD24 H0YB80 P63104
		NCBI	7534
		KEGG signaling	Oocyte meiosis Cell cycle PI3K-Akt signaling pathway Hippo signaling pathway
27	HSP90AB1	ENSG00000096384	heat shock protein 90 alpha family class B member 1
		UniProt	P08238
		NCBI	3326
		KEGG signaling	Antigen processing and presentation NOD-like receptor signaling pathway PI3K-Akt signaling pathway Estrogen signaling pathway Progesterone-mediated oocyte maturation IL-17 signaling pathway
		KEGG metabolic	Protein processing in endoplasmic reticulum
16	VIM	ENSG00000026025	vimentin
		UniProt	A0A1B0GTT5 A0A1B0GVG8 B0YJC4 B0YJC5 P08670
		NCBI	7431
28	CCT8	ENSG00000156261	chaperonin containing TCP1 subunit 8
		UniProt	H7C2U0 H7C4C8 P50990
		NCBI	10694
25	YWHAE	ENSG00000108953	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein epsilon
		UniProt	B4DJF2 I3L0W5 I3L3T1 K7EIT4 K7EM20 P62258
		NCBI	7531
		KEGG signaling	Neurotrophin signaling pathway NOD-like receptor signaling pathway Oocyte meiosis Cell cycle PI3K-Akt signaling pathway Hippo signaling pathway

Enrichment analysis

Search for enrichment of pathways or functional gene sets for your subnetwork genes

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	jSquid_subnetworks.xml	322.41 KB
	H.sapiens_subnetwork.tsv	69.86 KB

Species:

Network information:

Filter Results:

Network appearance:

ENSG00000116560

PSPC1

ELAVL1

DDX39B

DDX5

HNRNPA1

SNRPA

HSPA8

CCT4

TUBB

PTBP1

HNRNPAB

KHDRBS1

ILF2

EEF1A1

HNRNPD

SREK1

NCL

TIAL1

PRMT1

MATR3

RUVBL2

EED

NONO

PABPC1

TUBA1B

YWHAZ

HSP90AB1

VIM

CCT8

YWHAE

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