Found 1 of 1 query genes

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Query interactions

Interaction partners
Confidence
Network
MEX
PIN
SCL
PHP
MIR
TFB
PEX
GIN
DOM
QMS
GRG
Evidence types
HSA
MMU
RNO
CFA
GGA
DRE
CIN
DME
CEL
BTA
SCE
ATH
SPO
BSU
ECO
PFA
DDI
SSO
SSC
MJA
OSA
Species
In Gold st.

ID Query gene
ID Query ortholog

Log-likelihood ratio (LLR)
	Highly positive
	Positive
	Zero
	Negative
	Highly negative
Known coupling
	This network
	Other network

2. ENSG00000115091
3. actin related protein 3
- 2. ACTR2
  3. actin related protein 2
  4. 1.000
  5. PPI
- 2. ARPC1B
  3. actin related protein 2…
  4. 1.000
  5. PPI
- 2. ARPC2
  3. actin related protein 2…
  4. 1.000
  5. PPI
- 2. ARPC3
  3. actin related protein 2…
  4. 1.000
  5. PPI
- 2. ARPC1A
  3. actin related protein 2…
  4. 1.000
  5. PPI
- 2. ARPC5L
  3. actin related protein 2…
  4. 1.000
  5. PPI
- 2. ARPC5
  3. actin related protein 2…
  4. 1.000
  5. PPI
- 2. CAPZA2
  3. capping actin protein o…
  4. 1.000
  5. PPI
- 2. ARPC4
  3. actin related protein 2…
  4. 1.000
  5. Complex
- 2. CTTN
  3. cortactin
  4. 1.000
  5. PPI
- 2. WASL
  3. WASP like actin nucleat…
  4. 1.000
  5. PPI
- 2. ACTB
  3. actin beta
  4. 1.000
  5. PPI
- 2. ACTG1
  3. actin gamma 1
  4. 1.000
  5. PPI
- 2. WASF2
  3. WASP family member 2
  4. 1.000
  5. PPI
- 2. CORO1A
  3. coronin 1A
  4. 1.000
  5. PPI
- 2. CORO1B
  3. coronin 1B
  4. 1.000
  5. PPI
- 2. WAS
  3. WASP actin nucleation p…
  4. 1.000
  5. PPI
- 2. ACTR3B
  3. actin related protein 3B
  4. 1.000
  5. PPI
- 2. CCT4
  3. chaperonin containing T…
  4. 1.000
  5. PPI
- 2. IQGAP1
  3. IQ motif containing GTP…
  4. 1.000
  5. PPI
- 2. CORO1C
  3. coronin 1C
  4. 1.000
  5. PPI
- 2. PPP1CB
  3. protein phosphatase 1 c…
  4. 1.000
  5. PPI
- 2. CCT7
  3. chaperonin containing T…
  4. 1.000
  5. PPI
- 2. DBN1
  3. drebrin 1
  4. 1.000
  5. PPI
- 2. CCT5
  3. chaperonin containing T…
  4. 1.000
  5. PPI
- 2. DBNL
  3. drebrin like
  4. 1.000
  5. PPI
- 2. HCLS1
  3. hematopoietic cell-spec…
  4. 1.000
  5. PPI
- 2. MYH9
  3. myosin heavy chain 9
  4. 1.000
  5. PPI
- 2. CCT2
  3. chaperonin containing T…
  4. 1.000
  5. PPI
- 2. CFL1
  3. cofilin 1
  4. 1.000
  5. Metabolic

Subnetwork gene interactions

ENSG00000115091

actin related protein 3

FunCoup

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Ensembl

ENSG00000115091

UniProt

NCBI

10096

CCT5

chaperonin containing TCP1 subunit 5

FunCoup

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Ensembl

ENSG00000150753

UniProt

NCBI

22948

WASL

WASP like actin nucleation promoting factor

FunCoup

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Ensembl

ENSG00000106299

UniProt

O00401

NCBI

8976

IQGAP1

IQ motif containing GTPase activating protein 1

FunCoup

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Ensembl

ENSG00000140575

UniProt

NCBI

8826

ARPC5L

actin related protein 2/3 complex subunit 5 like

FunCoup

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Ensembl

ENSG00000136950

UniProt

Q9BPX5

NCBI

81873

CORO1B

coronin 1B

FunCoup

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Ensembl

ENSG00000172725

UniProt

NCBI

57175

CCT7

chaperonin containing TCP1 subunit 7

FunCoup

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Ensembl

ENSG00000135624

UniProt

NCBI

10574

ARPC2

actin related protein 2/3 complex subunit 2

FunCoup

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Ensembl

ENSG00000163466

UniProt

NCBI

10109

ACTG1

actin gamma 1

FunCoup

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Ensembl

ENSG00000184009

UniProt

NCBI

DBNL

drebrin like

FunCoup

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Ensembl

ENSG00000136279

UniProt

NCBI

28988

WASF2

WASP family member 2

FunCoup

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Ensembl

ENSG00000158195

UniProt

Q9Y6W5

NCBI

10163

CCT2

chaperonin containing TCP1 subunit 2

FunCoup

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Ensembl

ENSG00000166226

UniProt

NCBI

10576

HCLS1

hematopoietic cell-specific Lyn substrate 1

FunCoup

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Ensembl

ENSG00000180353

UniProt

NCBI

3059

CAPZA2

capping actin protein of muscle Z-line subunit alpha 2

FunCoup

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Ensembl

ENSG00000198898

UniProt

NCBI

DBN1

drebrin 1

FunCoup

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Ensembl

ENSG00000113758

UniProt

NCBI

1627

CTTN

cortactin

FunCoup

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Ensembl

ENSG00000085733

UniProt

NCBI

2017

WAS

WASP actin nucleation promoting factor

FunCoup

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Ensembl

ENSG00000015285

UniProt

NCBI

7454

MYH9

myosin heavy chain 9

FunCoup

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Ensembl

ENSG00000100345

UniProt

NCBI

4627

ARPC4

actin related protein 2/3 complex subunit 4

FunCoup

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Ensembl

ENSG00000241553

UniProt

NCBI

10093

CORO1C

coronin 1C

FunCoup

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Ensembl

ENSG00000110880

UniProt

NCBI

23603

CORO1A

coronin 1A

FunCoup

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Ensembl

ENSG00000102879

UniProt

NCBI

11151

ACTB

actin beta

FunCoup

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Ensembl

ENSG00000075624

UniProt

NCBI

ARPC1B

actin related protein 2/3 complex subunit 1B

FunCoup

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Ensembl

ENSG00000130429

UniProt

NCBI

10095

ACTR2

actin related protein 2

FunCoup

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Ensembl

ENSG00000138071

UniProt

NCBI

10097

ACTR3B

actin related protein 3B

FunCoup

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Ensembl

ENSG00000133627

UniProt

Q9P1U1

NCBI

57180

CFL1

cofilin 1

FunCoup

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Ensembl

ENSG00000172757

UniProt

NCBI

1072

ARPC5

actin related protein 2/3 complex subunit 5

FunCoup

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Ensembl

ENSG00000162704

UniProt

NCBI

10092

CCT4

chaperonin containing TCP1 subunit 4

FunCoup

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Ensembl

ENSG00000115484

UniProt

P50991

NCBI

10575

ARPC1A

actin related protein 2/3 complex subunit 1A

FunCoup

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Ensembl

ENSG00000241685

UniProt

NCBI

10552

PPP1CB

protein phosphatase 1 catalytic subunit beta

FunCoup

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Ensembl

ENSG00000213639

UniProt

NCBI

5500

ARPC3

actin related protein 2/3 complex subunit 3

FunCoup

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Ensembl

ENSG00000111229

UniProt

NCBI

10094

Query genes

		Identifier	Description
30	ENSG00000115091	ENSG00000115091	actin related protein 3
		UniProt	B4DXW1 F8WDR7 F8WE84 F8WEW2 P61158
		NCBI	10096
		KEGG signaling	Tight junction

Subnetwork genes

		Identifier	Description
30	CCT5	ENSG00000150753	chaperonin containing TCP1 subunit 5
		UniProt	B7ZAR1 D6RIZ7 E7ENZ3 E9PCA1 H0Y914 H0Y958 P48643
		NCBI	22948
28	WASL	ENSG00000106299	WASP like actin nucleation promoting factor
		UniProt	O00401
		NCBI	8976
		KEGG signaling	Adherens junction
		KEGG metabolic	Endocytosis
27	IQGAP1	ENSG00000140575	IQ motif containing GTPase activating protein 1
		UniProt	A0A087WWP1 A0A087X225 A0A0J9YXZ5 H0YKA5 H0YLE8 P46940
		NCBI	8826
		KEGG signaling	Adherens junction
27	ARPC5L	ENSG00000136950	actin related protein 2/3 complex subunit 5 like
		UniProt	Q9BPX5
		NCBI	81873
		KEGG signaling	Fc gamma R-mediated phagocytosis
		KEGG metabolic	Endocytosis
29	CORO1B	ENSG00000172725	coronin 1B
		UniProt	A0A087WW53 F5H0D2 F5H390 Q9BR76
		NCBI	57175
30	CCT7	ENSG00000135624	chaperonin containing TCP1 subunit 7
		UniProt	A0A0D9SG95 F8WAM2 F8WBP8 Q99832
		NCBI	10574
30	ARPC2	ENSG00000163466	actin related protein 2/3 complex subunit 2
		UniProt	C9JTV5 G5E9J0 G5E9S7 H7C3F9 O15144
		NCBI	10109
		KEGG signaling	Fc gamma R-mediated phagocytosis
		KEGG metabolic	Endocytosis
30	ACTG1	ENSG00000184009	actin gamma 1
		UniProt	I3L1U9 I3L3I0 I3L3R2 I3L4N8 J3KT65 K7EM38 P63261
		NCBI	71
		KEGG signaling	Rap1 signaling pathway Focal adhesion Adherens junction Tight junction Apoptosis Thyroid hormone signaling pathway Leukocyte transendothelial migration Hippo signaling pathway Oxytocin signaling pathway
		KEGG metabolic	Phagosome
28	DBNL	ENSG00000136279	drebrin like
		UniProt	B4DDD6 F2Z2V3 F2Z3E3 F8WB73 F8WBB2 F8WBG8 F8WC20 F8WCK3 F8WFE1 H0Y5J4 H7C111 Q9UJU6
		NCBI	28988
22	WASF2	ENSG00000158195	WASP family member 2
		UniProt	Q9Y6W5
		NCBI	10163
		KEGG signaling	Fc gamma R-mediated phagocytosis Adherens junction
28	CCT2	ENSG00000166226	chaperonin containing TCP1 subunit 2
		UniProt	F5GWF6 F8VQ14 P78371
		NCBI	10576
21	HCLS1	ENSG00000180353	hematopoietic cell-specific Lyn substrate 1
		UniProt	E7EVW7 F8WDD5 F8WEZ6 P14317
		NCBI	3059
		KEGG signaling	Tight junction
29	CAPZA2	ENSG00000198898	capping actin protein of muscle Z-line subunit alpha 2
		UniProt	A0A0D9SET8 C9J7V0 C9JCZ4 C9JUG7 F8W9N7 F8WED3 P47755
		NCBI	830
		KEGG metabolic	Endocytosis
23	DBN1	ENSG00000113758	drebrin 1
		UniProt	D6R9Q9 D6R9W4 D6RCR4 D6RFI1 Q16643
		NCBI	1627
25	CTTN	ENSG00000085733	cortactin
		UniProt	H0YCD9 H0YEV2 Q14247
		NCBI	2017
		KEGG signaling	Tight junction
25	WAS	ENSG00000015285	WASP actin nucleation promoting factor
		UniProt	C9J3B7 P42768
		NCBI	7454
		KEGG signaling	Fc gamma R-mediated phagocytosis Adherens junction Tight junction Chemokine signaling pathway
30	MYH9	ENSG00000100345	myosin heavy chain 9
		UniProt	B1AH99 P35579 Q5BKV1
		NCBI	4627
		KEGG signaling	Tight junction Vascular smooth muscle contraction
29	ARPC4	ENSG00000241553	actin related protein 2/3 complex subunit 4
		UniProt	F8WDD7 F8WDW3 P59998 R4GN08
		NCBI	10093
		KEGG signaling	Fc gamma R-mediated phagocytosis
		KEGG metabolic	Endocytosis
29	CORO1C	ENSG00000110880	coronin 1C
		UniProt	B4E3S0 F8VRE9 F8VSA4 F8VTT6 F8VUX3 F8VV53 F8VVB7 F8W1H8 H0YHL7 Q9ULV4
		NCBI	23603
28	CORO1A	ENSG00000102879	coronin 1A
		UniProt	H3BNA2 H3BRJ0 H3BRY3 H3BSL1 H3BTU6 H3BU76 P31146
		NCBI	11151
		KEGG metabolic	Phagosome
30	ACTB	ENSG00000075624	actin beta
		UniProt	A0A2R8Y793 A0A2R8YEA7 A0A2R8YFE2 A0A2R8YGF8 C9JTX5 C9JUM1 C9JZR7 E7EVS6 G5E9R0 P60709
		NCBI	60
		KEGG signaling	Focal adhesion Rap1 signaling pathway Adherens junction Tight junction Apoptosis Thyroid hormone signaling pathway Leukocyte transendothelial migration Hippo signaling pathway Oxytocin signaling pathway
		KEGG metabolic	Phagosome
30	ARPC1B	ENSG00000130429	actin related protein 2/3 complex subunit 1B
		UniProt	C9JBJ7 C9JEY1 C9JM51 C9JTT6 C9K057 F8VXW2 F8WEB3 O15143
		NCBI	10095
		KEGG signaling	Fc gamma R-mediated phagocytosis
		KEGG metabolic	Endocytosis
30	ACTR2	ENSG00000138071	actin related protein 2
		UniProt	A0A1B0GWD0 A0A1B0GWH0 F5H6T1 P61160
		NCBI	10097
		KEGG signaling	Tight junction
26	ACTR3B	ENSG00000133627	actin related protein 3B
		UniProt	Q9P1U1
		NCBI	57180
		KEGG signaling	Tight junction
30	CFL1	ENSG00000172757	cofilin 1
		UniProt	E9PK25 E9PLJ3 E9PP50 E9PQB7 E9PS23 G3V1A4 P23528
		NCBI	1072
		KEGG signaling	Fc gamma R-mediated phagocytosis
30	ARPC5	ENSG00000162704	actin related protein 2/3 complex subunit 5
		UniProt	B1ALC0 O15511
		NCBI	10092
		KEGG signaling	Fc gamma R-mediated phagocytosis
		KEGG metabolic	Endocytosis
28	CCT4	ENSG00000115484	chaperonin containing TCP1 subunit 4
		UniProt	P50991
		NCBI	10575
30	ARPC1A	ENSG00000241685	actin related protein 2/3 complex subunit 1A
		UniProt	E9PF58 Q92747
		NCBI	10552
		KEGG signaling	Fc gamma R-mediated phagocytosis
		KEGG metabolic	Endocytosis
24	PPP1CB	ENSG00000213639	protein phosphatase 1 catalytic subunit beta
		UniProt	C9J9S3 C9JP48 E7ETD8 F8WE71 H0Y3Y6 P62140
		NCBI	5500
		KEGG signaling	Long-term potentiation Focal adhesion Oocyte meiosis cAMP signaling pathway cGMP-PKG signaling pathway Adrenergic signaling in cardiomyocytes Dopaminergic synapse Vascular smooth muscle contraction Hippo signaling pathway Insulin signaling pathway Oxytocin signaling pathway
		KEGG metabolic	mRNA surveillance pathway
30	ARPC3	ENSG00000111229	actin related protein 2/3 complex subunit 3
		UniProt	C9JZD1 F8VR50 O15145
		NCBI	10094
		KEGG signaling	Fc gamma R-mediated phagocytosis
		KEGG metabolic	Endocytosis

Enrichment analysis

Search for enrichment of pathways or functional gene sets for your subnetwork genes

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	jSquid_subnetworks.xml	335.75 KB
	H.sapiens_subnetwork.tsv	79.83 KB

Species:

Network information:

Filter Results:

Network appearance:

ENSG00000115091

CCT5

WASL

IQGAP1

ARPC5L

CORO1B

CCT7

ARPC2

ACTG1

DBNL

WASF2

CCT2

HCLS1

CAPZA2

DBN1

CTTN

WAS

MYH9

ARPC4

CORO1C

CORO1A

ACTB

ARPC1B

ACTR2

ACTR3B

CFL1

ARPC5

CCT4

ARPC1A

PPP1CB

ARPC3

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