Found 1 of 1 query genes

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Query interactions

Interaction partners
Confidence
Network
MEX
PIN
SCL
PHP
MIR
TFB
PEX
GIN
DOM
QMS
GRG
Evidence types
HSA
MMU
RNO
CFA
GGA
DRE
CIN
DME
CEL
BTA
SCE
ATH
SPO
BSU
ECO
PFA
DDI
SSO
SSC
MJA
OSA
Species
In Gold st.

ID Query gene
ID Query ortholog

Log-likelihood ratio (LLR)
	Highly positive
	Positive
	Zero
	Negative
	Highly negative
Known coupling
	This network
	Other network

2. ENSG00000113657
3. dihydropyrimidinase lik…
- 2. CRMP1
  3. collapsin response medi…
  4. 1.000
  5. PPI
- 2. G6PD
  3. glucose-6-phosphate deh…
  4. 0.996
  5. Metabolic
- 2. DPYSL2
  3. dihydropyrimidinase lik…
  4. 0.996
  5. PPI
- 2. GLUL
  3. glutamate-ammonia ligase
  4. 0.994
  5. Metabolic
- 2. NPEPPS
  3. aminopeptidase puromyci…
  4. 0.990
  5. Metabolic
- 2. P4HB
  3. prolyl 4-hydroxylase su…
  4. 0.987
  5. Metabolic
- 2. PYGL
  3. glycogen phosphorylase L
  4. 0.986
  5. Metabolic
- 2. PYGB
  3. glycogen phosphorylase B
  4. 0.986
  5. Metabolic
- 2. OAT
  3. ornithine aminotransfer…
  4. 0.980
  5. Metabolic
- 2. ME3
  3. malic enzyme 3
  4. 0.973
  5. Metabolic
- 2. RPLP2
  3. ribosomal protein later…
  4. 0.970
  5. Complex
- 2. DPYSL5
  3. dihydropyrimidinase lik…
  4. 0.970
  5. PPI
- 2. GLUD1
  3. glutamate dehydrogenase…
  4. 0.953
  5. Metabolic
- 2. ME2
  3. malic enzyme 2
  4. 0.944
  5. Metabolic
- 2. GNAI2
  3. G protein subunit alpha…
  4. 0.935
  5. Metabolic
- 2. ACAA1
  3. acetyl-CoA acyltransfer…
  4. 0.922
  5. Metabolic
- 2. EEF2
  3. eukaryotic translation …
  4. 0.922
  5. PPI
- 2. ALLC
  3. allantoicase
  4. 0.917
  5. Metabolic
- 2. KCNAB2
  3. potassium voltage-gated…
  4. 0.900
  5. Metabolic
- 2. PSMA3
  3. proteasome 20S subunit …
  4. 0.889
  5. Metabolic
- 2. ASS1
  3. argininosuccinate synth…
  4. 0.886
  5. Metabolic
- 2. PYGM
  3. glycogen phosphorylase,…
  4. 0.886
  5. Metabolic
- 2. PARVA
  3. parvin alpha
  4. 0.874
  5. Metabolic
- 2. CCT8
  3. chaperonin containing T…
  4. 0.874
  5. Metabolic
- 2. YPEL2
  3. yippee like 2
  4. 0.861
  5. Metabolic
- 2. C16orf70
  3. chromosome 16 open read…
  4. 0.854
  5. Metabolic
- 2. CLIC4
  3. chloride intracellular …
  4. 0.851
  5. Metabolic
- 2. YPEL1
  3. yippee like 1
  4. 0.849
  5. Metabolic
- 2. DPYSL4
  3. dihydropyrimidinase lik…
  4. 0.844
  5. PPI
- 2. SLC17A8
  3. solute carrier family 1…
  4. 0.838
  5. PPI

Subnetwork gene interactions

ENSG00000113657

dihydropyrimidinase like 3

FunCoup

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Ensembl

ENSG00000113657

UniProt

NCBI

1809

GLUD1

glutamate dehydrogenase 1

FunCoup

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Ensembl

ENSG00000148672

UniProt

P00367

NCBI

2746

PYGM

glycogen phosphorylase, muscle associated

FunCoup

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Ensembl

ENSG00000068976

UniProt

P11217

NCBI

5837

GLUL

glutamate-ammonia ligase

FunCoup

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Ensembl

ENSG00000135821

UniProt

NCBI

2752

G6PD

glucose-6-phosphate dehydrogenase

FunCoup

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Ensembl

ENSG00000160211

UniProt

NCBI

2539

EEF2

eukaryotic translation elongation factor 2

FunCoup

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Ensembl

ENSG00000167658

UniProt

NCBI

1938

ME3

malic enzyme 3

FunCoup

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Ensembl

ENSG00000151376

UniProt

NCBI

10873

PSMA3

proteasome 20S subunit alpha 3

FunCoup

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Ensembl

ENSG00000100567

UniProt

NCBI

5684

DPYSL4

dihydropyrimidinase like 4

FunCoup

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Ensembl

ENSG00000151640

UniProt

NCBI

10570

YPEL2

yippee like 2

FunCoup

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Ensembl

ENSG00000175155

UniProt

NCBI

388403

DPYSL5

dihydropyrimidinase like 5

FunCoup

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Ensembl

ENSG00000157851

UniProt

NCBI

56896

CRMP1

collapsin response mediator protein 1

FunCoup

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Ensembl

ENSG00000072832

UniProt

NCBI

1400

SLC17A8

solute carrier family 17 member 8

FunCoup

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Ensembl

ENSG00000179520

UniProt

Q8NDX2

NCBI

246213

ASS1

argininosuccinate synthase 1

FunCoup

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Ensembl

ENSG00000130707

UniProt

NCBI

DPYSL2

dihydropyrimidinase like 2

FunCoup

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Ensembl

ENSG00000092964

UniProt

NCBI

1808

CLIC4

chloride intracellular channel 4

FunCoup

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Ensembl

ENSG00000169504

UniProt

Q9Y696

NCBI

25932

NPEPPS

aminopeptidase puromycin sensitive

FunCoup

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Ensembl

ENSG00000141279

UniProt

NCBI

9520

PYGL

glycogen phosphorylase L

FunCoup

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Ensembl

ENSG00000100504

UniProt

NCBI

5836

PYGB

glycogen phosphorylase B

FunCoup

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Ensembl

ENSG00000100994

UniProt

NCBI

5834

OAT

ornithine aminotransferase

FunCoup

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Ensembl

ENSG00000065154

UniProt

P04181

NCBI

4942

KCNAB2

potassium voltage-gated channel subfamily A regulatory beta subunit 2

FunCoup

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Ensembl

ENSG00000069424

UniProt

NCBI

8514

ME2

malic enzyme 2

FunCoup

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Ensembl

ENSG00000082212

UniProt

NCBI

4200

RPLP2

ribosomal protein lateral stalk subunit P2

FunCoup

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Ensembl

ENSG00000177600

UniProt

NCBI

6181

ACAA1

acetyl-CoA acyltransferase 1

FunCoup

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Ensembl

ENSG00000060971

UniProt

NCBI

PARVA

parvin alpha

FunCoup

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Ensembl

ENSG00000197702

UniProt

NCBI

55742

CCT8

chaperonin containing TCP1 subunit 8

FunCoup

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Ensembl

ENSG00000156261

UniProt

NCBI

10694

P4HB

prolyl 4-hydroxylase subunit beta

FunCoup

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Ensembl

ENSG00000185624

UniProt

NCBI

5034

GNAI2

G protein subunit alpha i2

FunCoup

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Ensembl

ENSG00000114353

UniProt

NCBI

2771

ALLC

allantoicase

FunCoup

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Ensembl

ENSG00000151360

UniProt

Q8N6M5

NCBI

55821

C16orf70

chromosome 16 open reading frame 70

FunCoup

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Ensembl

ENSG00000125149

UniProt

NCBI

80262

YPEL1

yippee like 1

FunCoup

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Ensembl

ENSG00000100027

UniProt

NCBI

29799

Query genes

		Identifier	Description
30	ENSG00000113657	ENSG00000113657	dihydropyrimidinase like 3
		UniProt	D6RF19 H0YB87 H0YBT4 Q14195
		NCBI	1809

Subnetwork genes

		Identifier	Description
22	GLUD1	ENSG00000148672	glutamate dehydrogenase 1
		UniProt	P00367
		NCBI	2746
		KEGG metabolic	Nitrogen metabolism Alanine, aspartate and glutamate metabolism D-Glutamine and D-glutamate metabolism Carbon metabolism Arginine biosynthesis
19	PYGM	ENSG00000068976	glycogen phosphorylase, muscle associated
		UniProt	P11217
		NCBI	5837
		KEGG signaling	Glucagon signaling pathway Insulin signaling pathway
		KEGG metabolic	Starch and sucrose metabolism
22	GLUL	ENSG00000135821	glutamate-ammonia ligase
		UniProt	A0A2R8YDT1 P15104
		NCBI	2752
		KEGG signaling	GABAergic synapse Glutamatergic synapse
		KEGG metabolic	Nitrogen metabolism Alanine, aspartate and glutamate metabolism Biosynthesis of amino acids Arginine biosynthesis Glyoxylate and dicarboxylate metabolism
24	G6PD	ENSG00000160211	glucose-6-phosphate dehydrogenase
		UniProt	E7EM57 E7EUI8 E9PD92 P11413
		NCBI	2539
		KEGG metabolic	Pentose phosphate pathway Glutathione metabolism Carbon metabolism
21	EEF2	ENSG00000167658	eukaryotic translation elongation factor 2
		UniProt	M0R0I6 P13639
		NCBI	1938
		KEGG signaling	AMPK signaling pathway Oxytocin signaling pathway
23	ME3	ENSG00000151376	malic enzyme 3
		UniProt	E9PKA0 E9PMB9 E9PND9 E9PNN2 Q16798 Q6TCH8
		NCBI	10873
		KEGG signaling	PPAR signaling pathway
		KEGG metabolic	Pyruvate metabolism Carbon metabolism
19	PSMA3	ENSG00000100567	proteasome 20S subunit alpha 3
		UniProt	G3V3W4 G3V4X5 G3V5N4 H0YJ03 P25788
		NCBI	5684
		KEGG metabolic	Proteasome
18	DPYSL4	ENSG00000151640	dihydropyrimidinase like 4
		UniProt	O14531 Q5T0Q6
		NCBI	10570
9	YPEL2	ENSG00000175155	yippee like 2
		UniProt	A0A5F9ZH55 Q96QA6
		NCBI	388403
22	DPYSL5	ENSG00000157851	dihydropyrimidinase like 5
		UniProt	E7ESV0 E7EWB4 E9PHT0 Q9BPU6
		NCBI	56896
22	CRMP1	ENSG00000072832	collapsin response mediator protein 1
		UniProt	E9PD68 Q14194
		NCBI	1400
4	SLC17A8	ENSG00000179520	solute carrier family 17 member 8
		UniProt	Q8NDX2
		NCBI	246213
		KEGG signaling	Synaptic vesicle cycle Glutamatergic synapse Retrograde endocannabinoid signaling
22	ASS1	ENSG00000130707	argininosuccinate synthase 1
		UniProt	P00966 Q5T6L5 Q5T6L6
		NCBI	445
		KEGG metabolic	Alanine, aspartate and glutamate metabolism Biosynthesis of amino acids Arginine biosynthesis
27	DPYSL2	ENSG00000092964	dihydropyrimidinase like 2
		UniProt	A0A1C7CYX9 E5RFU4 Q16555
		NCBI	1808
20	CLIC4	ENSG00000169504	chloride intracellular channel 4
		UniProt	Q9Y696
		NCBI	25932
23	NPEPPS	ENSG00000141279	aminopeptidase puromycin sensitive
		UniProt	E9PI82 E9PJ74 E9PJF9 E9PJY4 E9PLK3 E9PP11 E9PPD4 E9PPZ2 E9PRQ5 H0YCQ5 H0YDG0 P55786
		NCBI	9520
23	PYGL	ENSG00000100504	glycogen phosphorylase L
		UniProt	E9PK47 P06737
		NCBI	5836
		KEGG signaling	Glucagon signaling pathway Insulin signaling pathway
		KEGG metabolic	Starch and sucrose metabolism
23	PYGB	ENSG00000100994	glycogen phosphorylase B
		UniProt	H0Y4Z6 P11216
		NCBI	5834
		KEGG signaling	Glucagon signaling pathway Insulin signaling pathway
		KEGG metabolic	Starch and sucrose metabolism
24	OAT	ENSG00000065154	ornithine aminotransferase
		UniProt	P04181
		NCBI	4942
		KEGG metabolic	Arginine and proline metabolism
15	KCNAB2	ENSG00000069424	potassium voltage-gated channel subfamily A regulatory beta subunit 2
		UniProt	A0A590UJ15 A0A590UJ35 A0A590UJ72 A0A590UJ79 A0A590UJB6 A0A590UJB8 A0A590UJI8 A0A590UJJ4 A0A590UJK5 A0A590UJU1 A0A590UJU4 A0A590UJV4 A0A590UJX9 A0A590UJY1 A0A590UK89 A0A5F9UN28 K7EIR5 K7EKU4 Q13303 Q5TG78 Q5TG81 Q5TG84
		NCBI	8514
21	ME2	ENSG00000082212	malic enzyme 2
		UniProt	A0A1W2PPH1 A0A1W2PPY2 A0A1W2PQ37 A0A1W2PQF8 A0A1W2PQH3 A0A1W2PQH4 A0A1W2PQT3 A0A1W2PQY8 A0A1W2PR68 A0A1W2PRH1 A0A1W2PRS2 A0A1W2PRY9 P23368
		NCBI	4200
		KEGG metabolic	Pyruvate metabolism Carbon metabolism
20	RPLP2	ENSG00000177600	ribosomal protein lateral stalk subunit P2
		UniProt	H0YDD8 P05387
		NCBI	6181
		KEGG metabolic	Ribosome
12	ACAA1	ENSG00000060971	acetyl-CoA acyltransferase 1
		UniProt	B4DVF4 C9JDE9 F2Z2Q6 F2Z3P7 H0Y4D4 H7C131 P09110
		NCBI	30
		KEGG signaling	PPAR signaling pathway
		KEGG metabolic	Peroxisome Biosynthesis of unsaturated fatty acids Valine, leucine and isoleucine degradation Fatty acid degradation alpha-Linolenic acid metabolism Fatty acid metabolism
3	PARVA	ENSG00000197702	parvin alpha
		UniProt	E9PS97 Q9NVD7
		NCBI	55742
		KEGG signaling	Focal adhesion
20	CCT8	ENSG00000156261	chaperonin containing TCP1 subunit 8
		UniProt	H7C2U0 H7C4C8 P50990
		NCBI	10694
24	P4HB	ENSG00000185624	prolyl 4-hydroxylase subunit beta
		UniProt	H0Y3Z3 H7BZ94 I3L0S0 I3L1Y5 I3L312 I3L398 I3L3P5 I3L3U6 I3L4M2 I3L514 I3NI03 P07237
		NCBI	5034
		KEGG metabolic	Protein processing in endoplasmic reticulum
22	GNAI2	ENSG00000114353	G protein subunit alpha i2
		UniProt	F8WBG4 F8WE78 P04899
		NCBI	2771
		KEGG signaling	Leukocyte transendothelial migration Apelin signaling pathway Adrenergic signaling in cardiomyocytes Chemokine signaling pathway Sphingolipid signaling pathway Rap1 signaling pathway Long-term depression cAMP signaling pathway Gap junction cGMP-PKG signaling pathway Melanogenesis Estrogen signaling pathway Dopaminergic synapse Relaxin signaling pathway Progesterone-mediated oocyte maturation GABAergic synapse Serotonergic synapse Cholinergic synapse Glutamatergic synapse Oxytocin signaling pathway Retrograde endocannabinoid signaling
5	ALLC	ENSG00000151360	allantoicase
		UniProt	Q8N6M5
		NCBI	55821
		KEGG metabolic	Purine metabolism
5	C16orf70	ENSG00000125149	chromosome 16 open reading frame 70
		UniProt	H3BRA5 H3BS58 H3BSG0 J3QRI8 Q9BSU1
		NCBI	80262
10	YPEL1	ENSG00000100027	yippee like 1
		UniProt	A0A5F9ZHD1 B5MCX2 O60688
		NCBI	29799

Enrichment analysis

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	jSquid_subnetworks.xml	278.16 KB
	H.sapiens_subnetwork.tsv	55.70 KB

Species:

Network information:

Filter Results:

Network appearance:

ENSG00000113657

GLUD1

PYGM

GLUL

G6PD

EEF2

ME3

PSMA3

DPYSL4

YPEL2

DPYSL5

CRMP1

SLC17A8

ASS1

DPYSL2

CLIC4

NPEPPS

PYGL

PYGB

OAT

KCNAB2

ME2

RPLP2

ACAA1

PARVA

CCT8

P4HB

GNAI2

ALLC

C16orf70

YPEL1

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