Found 1 of 1 query genes

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Query interactions

Interaction partners
Confidence
Network
MEX
PIN
SCL
PHP
MIR
TFB
PEX
GIN
DOM
QMS
GRG
Evidence types
HSA
MMU
RNO
CFA
GGA
DRE
CIN
DME
CEL
BTA
SCE
ATH
SPO
BSU
ECO
PFA
DDI
SSO
SSC
MJA
OSA
Species
In Gold st.

ID Query gene
ID Query ortholog

Log-likelihood ratio (LLR)
	Highly positive
	Positive
	Zero
	Negative
	Highly negative
Known coupling
	This network
	Other network

2. ENSG00000113327
3. gamma-aminobutyric acid…
- 2. GABRA1
  3. gamma-aminobutyric acid…
  4. 1.000
  5. PPI
- 2. GABRB2
  3. gamma-aminobutyric acid…
  4. 1.000
  5. PPI
- 2. GABRB3
  3. gamma-aminobutyric acid…
  4. 1.000
  5. PPI
- 2. GABRA2
  3. gamma-aminobutyric acid…
  4. 1.000
  5. Complex
- 2. GABRA5
  3. gamma-aminobutyric acid…
  4. 1.000
  5. PPI
- 2. GABRG1
  3. gamma-aminobutyric acid…
  4. 1.000
  5. PPI
- 2. KCTD16
  3. potassium channel tetra…
  4. 0.999
  5. PPI
- 2. GABRA3
  3. gamma-aminobutyric acid…
  4. 0.999
  5. PPI
- 2. OLFM4
  3. olfactomedin 4
  4. 0.998
  5. PPI
- 2. GABRA6
  3. gamma-aminobutyric acid…
  4. 0.997
  5. Complex
- 2. GLRB
  3. glycine receptor beta
  4. 0.936
  5. Metabolic
- 2. SNAP25
  3. synaptosome associated …
  4. 0.869
  5. Metabolic
- 2. GABRA4
  3. gamma-aminobutyric acid…
  4. 0.848
  5. PPI
- 2. STXBP1
  3. syntaxin binding protei…
  4. 0.840
  5. Metabolic
- 2. SYNJ1
  3. synaptojanin 1
  4. 0.804
  5. Metabolic
- 2. KCNC1
  3. potassium voltage-gated…
  4. 0.803
  5. Metabolic
- 2. KCNA1
  3. potassium voltage-gated…
  4. 0.795
  5. Metabolic
- 2. SLC32A1
  3. solute carrier family 3…
  4. 0.776
  5. Metabolic
- 2. CANX
  3. calnexin
  4. 0.761
  5. PPI
- 2. SV2A
  3. synaptic vesicle glycop…
  4. 0.746
  5. Metabolic
- 2. GABARAP
  3. GABA type A receptor-as…
  4. 0.741
  5. PPI
- 2. SLC4A10
  3. solute carrier family 4…
  4. 0.737
  5. Metabolic
- 2. GLRA2
  3. glycine receptor alpha 2
  4. 0.727
  5. PPI
- 2. SLC6A1
  3. solute carrier family 6…
  4. 0.680
  5. Metabolic
- 2. ZDHHC17
  3. zinc finger DHHC-type p…
  4. 0.654
  5. Metabolic
- 2. KCNA4
  3. potassium voltage-gated…
  4. 0.645
  5. Metabolic
- 2. PCSK2
  3. proprotein convertase s…
  4. 0.606
  5. Signaling
- 2. LRRTM3
  3. leucine rich repeat tra…
  4. 0.586
  5. PPI
- 2. SLC8A3
  3. solute carrier family 8…
  4. 0.582
  5. Metabolic
- 2. GAD2
  3. glutamate decarboxylase…
  4. 0.576
  5. Metabolic

Subnetwork gene interactions

ENSG00000113327

gamma-aminobutyric acid type A receptor subunit gamma2

FunCoup

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Ensembl

ENSG00000113327

UniProt

NCBI

2566

KCNA1

potassium voltage-gated channel subfamily A member 1

FunCoup

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Ensembl

ENSG00000111262

UniProt

NCBI

3736

SLC6A1

solute carrier family 6 member 1

FunCoup

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Ensembl

ENSG00000157103

UniProt

NCBI

6529

STXBP1

syntaxin binding protein 1

FunCoup

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Ensembl

ENSG00000136854

UniProt

NCBI

6812

KCNC1

potassium voltage-gated channel subfamily C member 1

FunCoup

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Ensembl

ENSG00000129159

UniProt

NCBI

3746

SNAP25

synaptosome associated protein 25

FunCoup

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Ensembl

ENSG00000132639

UniProt

NCBI

6616

PCSK2

proprotein convertase subtilisin/kexin type 2

FunCoup

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Ensembl

ENSG00000125851

UniProt

P16519

NCBI

5126

GABRB3

gamma-aminobutyric acid type A receptor subunit beta3

FunCoup

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Ensembl

ENSG00000166206

UniProt

NCBI

2562

GABRB2

gamma-aminobutyric acid type A receptor subunit beta2

FunCoup

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Ensembl

ENSG00000145864

UniProt

NCBI

2561

GABRA5

gamma-aminobutyric acid type A receptor subunit alpha5

FunCoup

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Ensembl

ENSG00000186297

UniProt

NCBI

2558

SLC32A1

solute carrier family 32 member 1

FunCoup

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Ensembl

ENSG00000101438

UniProt

Q9H598

NCBI

140679

GABRA4

gamma-aminobutyric acid type A receptor subunit alpha4

FunCoup

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Ensembl

ENSG00000109158

UniProt

NCBI

2557

CANX

calnexin

FunCoup

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Ensembl

ENSG00000127022

UniProt

NCBI

GABRA1

gamma-aminobutyric acid type A receptor subunit alpha1

FunCoup

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Ensembl

ENSG00000022355

UniProt

NCBI

2554

GABRA2

gamma-aminobutyric acid type A receptor subunit alpha2

FunCoup

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Ensembl

ENSG00000151834

UniProt

NCBI

2555

GLRB

glycine receptor beta

FunCoup

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Ensembl

ENSG00000109738

UniProt

NCBI

2743

GLRA2

glycine receptor alpha 2

FunCoup

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Ensembl

ENSG00000101958

UniProt

NCBI

2742

SLC4A10

solute carrier family 4 member 10

FunCoup

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Ensembl

ENSG00000144290

UniProt

NCBI

57282

GABRA3

gamma-aminobutyric acid type A receptor subunit alpha3

FunCoup

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Ensembl

ENSG00000011677

UniProt

P34903

NCBI

2556

GAD2

glutamate decarboxylase 2

FunCoup

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Ensembl

ENSG00000136750

UniProt

NCBI

2572

GABRA6

gamma-aminobutyric acid type A receptor subunit alpha6

FunCoup

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Ensembl

ENSG00000145863

UniProt

NCBI

2559

KCNA4

potassium voltage-gated channel subfamily A member 4

FunCoup

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Ensembl

ENSG00000182255

UniProt

P22459

NCBI

3739

SLC8A3

solute carrier family 8 member A3

FunCoup

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Ensembl

ENSG00000100678

UniProt

NCBI

6547

ZDHHC17

zinc finger DHHC-type palmitoyltransferase 17

FunCoup

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Ensembl

ENSG00000186908

UniProt

NCBI

23390

GABRG1

gamma-aminobutyric acid type A receptor subunit gamma1

FunCoup

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Ensembl

ENSG00000163285

UniProt

Q8N1C3

NCBI

2565

KCTD16

potassium channel tetramerization domain containing 16

FunCoup

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Ensembl

ENSG00000183775

UniProt

Q68DU8

NCBI

57528

SV2A

synaptic vesicle glycoprotein 2A

FunCoup

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Ensembl

ENSG00000159164

UniProt

Q7L0J3

NCBI

9900

LRRTM3

leucine rich repeat transmembrane neuronal 3

FunCoup

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Ensembl

ENSG00000198739

UniProt

Q86VH5

NCBI

347731

OLFM4

olfactomedin 4

FunCoup

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Ensembl

ENSG00000102837

UniProt

Q6UX06

NCBI

10562

SYNJ1

synaptojanin 1

FunCoup

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Ensembl

ENSG00000159082

UniProt

NCBI

8867

GABARAP

GABA type A receptor-associated protein

FunCoup

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Ensembl

ENSG00000170296

UniProt

NCBI

11337

Query genes

		Identifier	Description
30	ENSG00000113327	ENSG00000113327	gamma-aminobutyric acid type A receptor subunit gamma2
		UniProt	A0A1W2PP56 A0A1W2PPN5 A0A1W2PPS4 A0A1W2PQ81 A0A1W2PQA6 A0A1W2PQR9 A0A1W2PQX1 A0A1W2PR49 A0A1W2PRM8 A0A1W2PRN4 A0A1W2PRU1 A0A1W2PRY3 A0A1W2PSF4 A0A1X7SBS5 A0A1X7SBZ8 A0A286YFI6 A8MWU7 E5RGJ0 E5RIG3 P18507
		NCBI	2566
		KEGG signaling	GABAergic synapse Neuroactive ligand-receptor interaction Retrograde endocannabinoid signaling

Subnetwork genes

		Identifier	Description
8	KCNA1	ENSG00000111262	potassium voltage-gated channel subfamily A member 1
		UniProt	A0A1W2PQM4 A0A1W2PRI2 Q09470
		NCBI	3736
20	SLC6A1	ENSG00000157103	solute carrier family 6 member 1
		UniProt	A0A2R8Y3X2 A0A2R8Y495 A0A2R8Y4I3 A0A2R8Y867 A0A2R8YCM3 A0A2R8YDD5 A0A2R8YEF0 A0A2R8YF74 A0A2R8YFI0 B7Z3C5 C9J5P8 P30531
		NCBI	6529
		KEGG signaling	Synaptic vesicle cycle GABAergic synapse
11	STXBP1	ENSG00000136854	syntaxin binding protein 1
		UniProt	A0A096LP33 A0A096LP52 A0A0D9SEH5 A0A0D9SEP9 A0A0D9SFQ7 A0A0D9SFW6 A0A0D9SG72 A0A1B0GTD8 A0A1B0GTP9 A0A1B0GUQ2 A0A1B0GVQ5 A0A1B0GVV9 A0A1B0GW76 A0A1B0GWF2 A0A2R8Y5D4 P61764
		NCBI	6812
		KEGG signaling	Synaptic vesicle cycle
11	KCNC1	ENSG00000129159	potassium voltage-gated channel subfamily C member 1
		UniProt	A0A1W2PNN0 A0A1W2PNZ3 A0A1W2PP60 A0A1W2PPN9 A0A1W2PPT0 A0A1W2PPX0 A0A1W2PRL7 P48547
		NCBI	3746
10	SNAP25	ENSG00000132639	synaptosome associated protein 25
		UniProt	A0A0A0MSS0 P60880
		NCBI	6616
		KEGG signaling	Synaptic vesicle cycle
6	PCSK2	ENSG00000125851	proprotein convertase subtilisin/kexin type 2
		UniProt	P16519
		NCBI	5126
13	GABRB3	ENSG00000166206	gamma-aminobutyric acid type A receptor subunit beta3
		UniProt	A0A1B0GU30 A0A1B0GVW3 F5H7N0 G3V373 G3V4W7 H0YJU6 P28472
		NCBI	2562
		KEGG signaling	GABAergic synapse Serotonergic synapse Neuroactive ligand-receptor interaction Retrograde endocannabinoid signaling
10	GABRB2	ENSG00000145864	gamma-aminobutyric acid type A receptor subunit beta2
		UniProt	B7Z279 E7EV50 P47870
		NCBI	2561
		KEGG signaling	GABAergic synapse Serotonergic synapse Neuroactive ligand-receptor interaction Retrograde endocannabinoid signaling
15	GABRA5	ENSG00000186297	gamma-aminobutyric acid type A receptor subunit alpha5
		UniProt	G3V296 G3V2G8 G3V2K2 G3V2Q9 G3V2Y5 G3V408 P31644
		NCBI	2558
		KEGG signaling	Taste transduction GABAergic synapse Neuroactive ligand-receptor interaction Retrograde endocannabinoid signaling
7	SLC32A1	ENSG00000101438	solute carrier family 32 member 1
		UniProt	Q9H598
		NCBI	140679
		KEGG signaling	Synaptic vesicle cycle GABAergic synapse Retrograde endocannabinoid signaling
11	GABRA4	ENSG00000109158	gamma-aminobutyric acid type A receptor subunit alpha4
		UniProt	D6R924 D6RB66 P48169
		NCBI	2557
		KEGG signaling	Taste transduction GABAergic synapse Neuroactive ligand-receptor interaction Retrograde endocannabinoid signaling
5	CANX	ENSG00000127022	calnexin
		UniProt	D6RAQ8 D6RAU8 D6RB85 D6RD16 D6RDP7 D6RFL1 D6RFW4 D6RG29 D6RGY2 D6RHJ3 H0Y9H1 H0Y9Q7 P27824
		NCBI	821
		KEGG signaling	Antigen processing and presentation
		KEGG metabolic	Phagosome Protein processing in endoplasmic reticulum
16	GABRA1	ENSG00000022355	gamma-aminobutyric acid type A receptor subunit alpha1
		UniProt	A0A0U1RQJ3 A0A0U1RRB2 A0A1B0GU82 A0A1B0GV38 A0A1B0GVW9 E5RHL6 E5RJS3 E5RK60 P14867
		NCBI	2554
		KEGG signaling	Taste transduction GABAergic synapse Neuroactive ligand-receptor interaction Retrograde endocannabinoid signaling
12	GABRA2	ENSG00000151834	gamma-aminobutyric acid type A receptor subunit alpha2
		UniProt	A0A0A0MTM5 D6RAA9 D6RB77 D6RBK9 D6RBL7 D6RCS5 E9PBQ7 G5E9Z6 H0Y9V8 P47869
		NCBI	2555
		KEGG signaling	Taste transduction GABAergic synapse Neuroactive ligand-receptor interaction Retrograde endocannabinoid signaling
7	GLRB	ENSG00000109738	glycine receptor beta
		UniProt	D6R9Y9 D6RD86 P48167
		NCBI	2743
		KEGG signaling	Neuroactive ligand-receptor interaction
10	GLRA2	ENSG00000101958	glycine receptor alpha 2
		UniProt	C9JBL4 P23416
		NCBI	2742
		KEGG signaling	Neuroactive ligand-receptor interaction
6	SLC4A10	ENSG00000144290	solute carrier family 4 member 10
		UniProt	C9J240 E7EW28 F8WDX9 Q6U841
		NCBI	57282
9	GABRA3	ENSG00000011677	gamma-aminobutyric acid type A receptor subunit alpha3
		UniProt	P34903
		NCBI	2556
		KEGG signaling	Taste transduction GABAergic synapse Retrograde endocannabinoid signaling Neuroactive ligand-receptor interaction
8	GAD2	ENSG00000136750	glutamate decarboxylase 2
		UniProt	A0A3B3IU09 Q05329 Q5VZ31
		NCBI	2572
		KEGG signaling	GABAergic synapse
		KEGG metabolic	Alanine, aspartate and glutamate metabolism Butanoate metabolism Taurine and hypotaurine metabolism beta-Alanine metabolism
7	GABRA6	ENSG00000145863	gamma-aminobutyric acid type A receptor subunit alpha6
		UniProt	E7EV53 H0YAS3 H0YBP3 H0YBS7 Q16445
		NCBI	2559
		KEGG signaling	Taste transduction GABAergic synapse Neuroactive ligand-receptor interaction Retrograde endocannabinoid signaling
5	KCNA4	ENSG00000182255	potassium voltage-gated channel subfamily A member 4
		UniProt	P22459
		NCBI	3739
2	SLC8A3	ENSG00000100678	solute carrier family 8 member A3
		UniProt	F2Z391 P57103
		NCBI	6547
		KEGG signaling	Olfactory transduction cGMP-PKG signaling pathway Calcium signaling pathway Apelin signaling pathway Adrenergic signaling in cardiomyocytes Cardiac muscle contraction
		KEGG metabolic	Protein digestion and absorption
4	ZDHHC17	ENSG00000186908	zinc finger DHHC-type palmitoyltransferase 17
		UniProt	F8VPW2 F8VUG7 F8VX48 H0YHF0 H0YHW0 H0YI74 H0YIK0 H0YIN1 H0YIP7 Q8IUH5
		NCBI	23390
4	GABRG1	ENSG00000163285	gamma-aminobutyric acid type A receptor subunit gamma1
		UniProt	Q8N1C3
		NCBI	2565
		KEGG signaling	GABAergic synapse Retrograde endocannabinoid signaling Neuroactive ligand-receptor interaction
3	KCTD16	ENSG00000183775	potassium channel tetramerization domain containing 16
		UniProt	Q68DU8
		NCBI	57528
7	SV2A	ENSG00000159164	synaptic vesicle glycoprotein 2A
		UniProt	Q7L0J3
		NCBI	9900
		KEGG signaling	ECM-receptor interaction
2	LRRTM3	ENSG00000198739	leucine rich repeat transmembrane neuronal 3
		UniProt	Q86VH5
		NCBI	347731
2	OLFM4	ENSG00000102837	olfactomedin 4
		UniProt	Q6UX06
		NCBI	10562
4	SYNJ1	ENSG00000159082	synaptojanin 1
		UniProt	A0A0D9SGJ6 C9J1Z6 C9JFZ1 C9JW66 H7BZ56 H7BZC2 J3KPK1 J3KQV8 O43426
		NCBI	8867
		KEGG signaling	Phosphatidylinositol signaling system
		KEGG metabolic	Inositol phosphate metabolism
1	GABARAP	ENSG00000170296	GABA type A receptor-associated protein
		UniProt	H6UMI1 I3L236 I3L3J4 O95166
		NCBI	11337
		KEGG signaling	NOD-like receptor signaling pathway FoxO signaling pathway Apelin signaling pathway GABAergic synapse
		KEGG metabolic	Autophagy - animal

Enrichment analysis

Search for enrichment of pathways or functional gene sets for your subnetwork genes

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	jSquid_subnetworks.xml	222.31 KB
	H.sapiens_subnetwork.tsv	21.31 KB

Species:

Network information:

Filter Results:

Network appearance:

ENSG00000113327

KCNA1

SLC6A1

STXBP1

KCNC1

SNAP25

PCSK2

GABRB3

GABRB2

GABRA5

SLC32A1

GABRA4

CANX

GABRA1

GABRA2

GLRB

GLRA2

SLC4A10

GABRA3

GAD2

GABRA6

KCNA4

SLC8A3

ZDHHC17

GABRG1

KCTD16

SV2A

LRRTM3

OLFM4

SYNJ1

GABARAP

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