Networks of functional couplings/associations

Query interactions

Interaction partners
Confidence
Network
MEX
PIN
SCL
PHP
MIR
TFB
PEX
GIN
DOM
QMS
GRG
Evidence types
HSA
MMU
RNO
CFA
GGA
DRE
CIN
DME
CEL
BTA
SCE
ATH
SPO
BSU
ECO
PFA
DDI
SSO
SSC
MJA
OSA
Species
In Gold st.

ID Query gene
ID Query ortholog

Log-likelihood ratio (LLR)
	Highly positive
	Positive
	Zero
	Negative
	Highly negative
Known coupling
	This network
	Other network

More

2. ENSG00000112182
3. BTB domain and CNC homo…
- 2. WDFY3
  3. WD repeat and FYVE doma…
  4. 0.893
  5. PPI
- 2. FOXO1
  3. forkhead box O1
  4. 0.703
  5. PPI
- 2. FOXP1
  3. forkhead box P1
  4. 0.561
  5. PPI
- 2. DST
  3. dystonin
  4. 0.515
  5. PPI
- 2. PLCG2
  3. phospholipase C gamma 2
  4. 0.511
  5. PPI
- 2. BACH1
  3. BTB domain and CNC homo…
  4. 0.492
  5. PPI
- 2. PTK2
  3. protein tyrosine kinase…
  4. 0.446
  5. Complex
- 2. BIRC6
  3. baculoviral IAP repeat …
  4. 0.434
  5. Complex
- 2. PACSIN2
  3. protein kinase C and ca…
  4. 0.410
  5. Complex

Subnetwork gene interactions

ENSG00000112182

BTB domain and CNC homolog 2

FunCoup

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Ensembl

ENSG00000112182

UniProt

NCBI

60468

PTK2

protein tyrosine kinase 2

FunCoup

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Ensembl

ENSG00000169398

UniProt

NCBI

5747

FOXP1

forkhead box P1

FunCoup

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Ensembl

ENSG00000114861

UniProt

NCBI

27086

WDFY3

WD repeat and FYVE domain containing 3

FunCoup

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Ensembl

ENSG00000163625

UniProt

NCBI

23001

PACSIN2

protein kinase C and casein kinase substrate in neurons 2

FunCoup

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Ensembl

ENSG00000100266

UniProt

NCBI

11252

PLCG2

phospholipase C gamma 2

FunCoup

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Ensembl

ENSG00000197943

UniProt

NCBI

5336

DST

dystonin

FunCoup

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Ensembl

ENSG00000151914

UniProt

NCBI

667

BIRC6

baculoviral IAP repeat containing 6

FunCoup

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Ensembl

ENSG00000115760

UniProt

NCBI

57448

BACH1

BTB domain and CNC homolog 1

FunCoup

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Ensembl

ENSG00000156273

UniProt

NCBI

571

FOXO1

forkhead box O1

FunCoup

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Ensembl

ENSG00000150907

UniProt

Q12778

NCBI

2308

Query genes

		Identifier	Description
9	ENSG00000112182	ENSG00000112182	BTB domain and CNC homolog 2
		UniProt	Q7Z6Q0 Q9BYV9
		NCBI	60468

Subnetwork genes

		Identifier	Description
3	PTK2	ENSG00000169398	protein tyrosine kinase 2
		UniProt	A0A1D5RMT1 B4DWJ1 E5RFW9 E5RG54 E5RG66 E5RG80 E5RG86 E5RGA6 E5RGP1 E5RH01 E5RH08 E5RH48 E5RHD8 E5RHK7 E5RI03 E5RI29 E5RI72 E5RII9 E5RIK4 E5RIR5 E5RJI4 E5RJN1 E5RJP0 E5RJQ2 E7ESA6 E9PEI4 H0YAS0 H0YB16 H0YB33 H0YB99 H0YBP1 H0YBZ1 Q05397
		NCBI	5747
		KEGG signaling	Focal adhesion ErbB signaling pathway Leukocyte transendothelial migration PI3K-Akt signaling pathway VEGF signaling pathway Chemokine signaling pathway
1	FOXP1	ENSG00000114861	forkhead box P1
		UniProt	A0A087WVT2 A0A087X2G3 A0A0B4J2F3 A0A3B3IRL7 A0A3B3IRS5 A0A3B3IRW5 A0A3B3IRY1 A0A3B3IS20 A0A3B3IS87 A0A3B3ISA4 A0A3B3ISQ3 A0A3B3ISQ6 A0A3B3ISQ7 A0A3B3IST0 A0A3B3IST6 A0A3B3IT14 A0A3B3IT26 A0A3B3IT66 A0A3B3ITZ4 A0A3B3IU08 A0A3B3IU15 A0A3B3IUB6 A0A5H1ZRR8 C9IYY1 C9J0F0 C9J5T4 G5E965 H0Y882 Q9H334
		NCBI	27086
2	WDFY3	ENSG00000163625	WD repeat and FYVE domain containing 3
		UniProt	A0A1D5RMR8 D6RJE4 H0Y9T6 H0YAD8 Q8IZQ1
		NCBI	23001
2	PACSIN2	ENSG00000100266	protein kinase C and casein kinase substrate in neurons 2
		UniProt	A0A0U1RR22 B0QYG7 B0QYG8 B0QYG9 H0Y923 Q9UNF0
		NCBI	11252
1	PLCG2	ENSG00000197943	phospholipase C gamma 2
		UniProt	A0A0A0MRF9 H3BMT7 H3BPZ3 H3BQV5 P16885
		NCBI	5336
		KEGG signaling	Thyroid hormone signaling pathway Leukocyte transendothelial migration NF-kappa B signaling pathway Calcium signaling pathway VEGF signaling pathway Phospholipase D signaling pathway Phosphatidylinositol signaling system Neurotrophin signaling pathway Fc gamma R-mediated phagocytosis Fc epsilon RI signaling pathway Ras signaling pathway B cell receptor signaling pathway Natural killer cell mediated cytotoxicity ErbB signaling pathway HIF-1 signaling pathway C-type lectin receptor signaling pathway
		KEGG metabolic	Inositol phosphate metabolism
1	DST	ENSG00000151914	dystonin
		UniProt	A0A0U1RQJ2 A0A494C073 A0A494C1D7 A0A494C1U5 E7ERX3 E7ETB9 E9PHM6 F6QMI7 F8W9J4 H0YAT7 H0YBX0 H0YC65 H0YC82 Q03001 Q5T0V7 Q6P0N6
		NCBI	667
1	BIRC6	ENSG00000115760	baculoviral IAP repeat containing 6
		UniProt	A0A3B3IUB9 H7C094 H7C3P0 Q9NR09
		NCBI	57448
		KEGG metabolic	Ubiquitin mediated proteolysis
1	BACH1	ENSG00000156273	BTB domain and CNC homolog 1
		UniProt	C9IYH8 C9IYR0 C9JMP6 F8VZL7 H7C4B6 M0QZP0 O14867
		NCBI	571
1	FOXO1	ENSG00000150907	forkhead box O1
		UniProt	Q12778
		NCBI	2308
		KEGG signaling	FoxO signaling pathway Thyroid hormone signaling pathway AMPK signaling pathway Glucagon signaling pathway Insulin signaling pathway

Enrichment analysis

Search for enrichment of pathways or functional gene sets for your subnetwork genes

To use PathwAX, first use the button below to copy the subnetwork genes and then paste them in PathwAX

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	jSquid_subnetworks.xml	105.02 KB
	H.sapiens_subnetwork.tsv	2.32 KB

Species:

Network information:

Filter Results:

Network appearance:

ENSG00000112182

PTK2

FOXP1

WDFY3

PACSIN2

PLCG2

DST

BIRC6

BACH1

FOXO1

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