Found 1 of 1 query genes

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Query interactions

Interaction partners
Confidence
Network
MEX
PIN
SCL
PHP
MIR
TFB
PEX
GIN
DOM
QMS
GRG
Evidence types
HSA
MMU
RNO
CFA
GGA
DRE
CIN
DME
CEL
BTA
SCE
ATH
SPO
BSU
ECO
PFA
DDI
SSO
SSC
MJA
OSA
Species
In Gold st.

ID Query gene
ID Query ortholog

Log-likelihood ratio (LLR)
	Highly positive
	Positive
	Zero
	Negative
	Highly negative
Known coupling
	This network
	Other network

2. ENSG00000111358
3. general transcription f…
- 2. GTF2H2
  3. general transcription f…
  4. 1.000
  5. PPI
- 2. CDK7
  3. cyclin dependent kinase…
  4. 1.000
  5. PPI
- 2. GTF2H2C
  3. GTF2H2 family member C
  4. 1.000
  5. PPI
- 2. GTF2H1
  3. general transcription f…
  4. 1.000
  5. PPI
- 2. ERCC3
  3. ERCC excision repair 3,…
  4. 1.000
  5. PPI
- 2. CCNH
  3. cyclin H
  4. 1.000
  5. PPI
- 2. GTF2H4
  3. general transcription f…
  4. 1.000
  5. PPI
- 2. MNAT1
  3. MNAT1 component of CDK …
  4. 1.000
  5. PPI
- 2. ERCC2
  3. ERCC excision repair 2,…
  4. 1.000
  5. PPI
- 2. GTF2H5
  3. general transcription f…
  4. 1.000
  5. PPI
- 2. POLR2C
  3. RNA polymerase II subun…
  4. 1.000
  5. PPI
- 2. GTF2B
  3. general transcription f…
  4. 1.000
  5. PPI
- 2. TBP
  3. TATA-box binding protein
  4. 1.000
  5. Metabolic
- 2. POLR2G
  3. RNA polymerase II subun…
  4. 1.000
  5. PPI
- 2. TAF5
  3. TATA-box binding protei…
  4. 0.999
  5. Metabolic
- 2. GTF2A1
  3. general transcription f…
  4. 0.999
  5. Metabolic
- 2. GTF2E1
  3. general transcription f…
  4. 0.999
  5. PPI
- 2. TAF2
  3. TATA-box binding protei…
  4. 0.999
  5. PPI
- 2. RPA2
  3. replication protein A2
  4. 0.999
  5. PPI
- 2. TBPL2
  3. TATA-box binding protei…
  4. 0.998
  5. Metabolic
- 2. POLR2B
  3. RNA polymerase II subun…
  4. 0.998
  5. Metabolic
- 2. POLR2J
  3. RNA polymerase II subun…
  4. 0.998
  5. PPI
- 2. GTF2E2
  3. general transcription f…
  4. 0.998
  5. PPI
- 2. RPA1
  3. replication protein A1
  4. 0.997
  5. PPI
- 2. TAF7
  3. TATA-box binding protei…
  4. 0.997
  5. Metabolic
- 2. TAF6
  3. TATA-box binding protei…
  4. 0.997
  5. Metabolic
- 2. ERCC5
  3. ERCC excision repair 5,…
  4. 0.997
  5. Complex
- 2. POLR2J3
  3. RNA polymerase II subun…
  4. 0.996
  5. PPI
- 2. POLR2I
  3. RNA polymerase II subun…
  4. 0.996
  5. PPI
- 2. POLR2J2
  3. RNA polymerase II subun…
  4. 0.996
  5. PPI

Subnetwork gene interactions

ENSG00000111358

general transcription factor IIH subunit 3

FunCoup

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Ensembl

ENSG00000111358

UniProt

NCBI

2967

TAF6

TATA-box binding protein associated factor 6

FunCoup

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Ensembl

ENSG00000106290

UniProt

NCBI

6878

GTF2E2

general transcription factor IIE subunit 2

FunCoup

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Ensembl

ENSG00000197265

UniProt

NCBI

2961

GTF2E1

general transcription factor IIE subunit 1

FunCoup

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Ensembl

ENSG00000153767

UniProt

NCBI

2960

TAF2

TATA-box binding protein associated factor 2

FunCoup

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Ensembl

ENSG00000064313

UniProt

NCBI

6873

MNAT1

MNAT1 component of CDK activating kinase

FunCoup

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Ensembl

ENSG00000020426

UniProt

NCBI

4331

GTF2H4

general transcription factor IIH subunit 4

FunCoup

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Ensembl

ENSG00000213780

UniProt

Q92759

NCBI

2968

GTF2A1

general transcription factor IIA subunit 1

FunCoup

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Ensembl

ENSG00000165417

UniProt

NCBI

2957

POLR2I

RNA polymerase II subunit I

FunCoup

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Ensembl

ENSG00000105258

UniProt

NCBI

5438

POLR2B

RNA polymerase II subunit B

FunCoup

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Ensembl

ENSG00000047315

UniProt

NCBI

5431

CCNH

cyclin H

FunCoup

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Ensembl

ENSG00000134480

UniProt

NCBI

GTF2H1

general transcription factor IIH subunit 1

FunCoup

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Ensembl

ENSG00000110768

UniProt

NCBI

2965

POLR2J2

RNA polymerase II subunit J2

FunCoup

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Ensembl

ENSG00000228049

UniProt

NCBI

GTF2H5

general transcription factor IIH subunit 5

FunCoup

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Ensembl

ENSG00000272047

UniProt

NCBI

404672

POLR2J

RNA polymerase II subunit J

FunCoup

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Ensembl

ENSG00000005075

UniProt

NCBI

5439

POLR2C

RNA polymerase II subunit C

FunCoup

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Ensembl

ENSG00000102978

UniProt

NCBI

5432

GTF2H2

general transcription factor IIH subunit 2

FunCoup

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Ensembl

ENSG00000145736

UniProt

NCBI

RPA1

replication protein A1

FunCoup

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Ensembl

ENSG00000132383

UniProt

NCBI

6117

RPA2

replication protein A2

FunCoup

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Ensembl

ENSG00000117748

UniProt

NCBI

6118

ERCC2

ERCC excision repair 2, TFIIH core complex helicase subunit

FunCoup

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Ensembl

ENSG00000104884

UniProt

NCBI

2068

GTF2B

general transcription factor IIB

FunCoup

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Ensembl

ENSG00000137947

UniProt

NCBI

2959

ERCC5

ERCC excision repair 5, endonuclease

FunCoup

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Ensembl

ENSG00000134899

UniProt

NCBI

2073

TBPL2

TATA-box binding protein like 2

FunCoup

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Ensembl

ENSG00000182521

UniProt

NCBI

387332

ERCC3

ERCC excision repair 3, TFIIH core complex helicase subunit

FunCoup

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Ensembl

ENSG00000163161

UniProt

NCBI

2071

POLR2G

RNA polymerase II subunit G

FunCoup

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Ensembl

ENSG00000168002

UniProt

NCBI

5436

POLR2J3

RNA polymerase II subunit J3

FunCoup

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Ensembl

ENSG00000168255

UniProt

NCBI

548644

TBP

TATA-box binding protein

FunCoup

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Ensembl

ENSG00000112592

UniProt

NCBI

6908

GTF2H2C

GTF2H2 family member C

FunCoup

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Ensembl

ENSG00000183474

UniProt

NCBI

CDK7

cyclin dependent kinase 7

FunCoup

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Ensembl

ENSG00000134058

UniProt

NCBI

1022

TAF5

TATA-box binding protein associated factor 5

FunCoup

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Ensembl

ENSG00000148835

UniProt

Q15542

NCBI

6877

TAF7

TATA-box binding protein associated factor 7

FunCoup

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Ensembl

ENSG00000178913

UniProt

NCBI

6879

Query genes

		Identifier	Description
30	ENSG00000111358	ENSG00000111358	general transcription factor IIH subunit 3
		UniProt	A0A087WYD5 F5GWD3 F5GX35 F5GXG6 F5H3G1 F5H4K7 F5H6X0 H0YFF7 Q13889
		NCBI	2967
		KEGG metabolic	Basal transcription factors Nucleotide excision repair

Subnetwork genes

		Identifier	Description
26	TAF6	ENSG00000106290	TATA-box binding protein associated factor 6
		UniProt	A0A1D5RMS5 C9J088 C9J7C4 C9JFL8 C9JHQ8 C9JI39 C9JIS2 C9JTY6 E5RHA1 E5RKA5 F8WEJ7 J3KR72 P49848
		NCBI	6878
		KEGG metabolic	Basal transcription factors
29	GTF2E2	ENSG00000197265	general transcription factor IIE subunit 2
		UniProt	E5RH41 E5RIW4 E5RK24 P29084
		NCBI	2961
		KEGG metabolic	Basal transcription factors
29	GTF2E1	ENSG00000153767	general transcription factor IIE subunit 1
		UniProt	C9IYL4 C9J329 E9PER7 P29083
		NCBI	2960
		KEGG metabolic	Basal transcription factors
26	TAF2	ENSG00000064313	TATA-box binding protein associated factor 2
		UniProt	E5RI28 H0YB55 H0YC37 H0YEX2 Q6P1X5
		NCBI	6873
		KEGG metabolic	Basal transcription factors
30	MNAT1	ENSG00000020426	MNAT1 component of CDK activating kinase
		UniProt	H0YJ92 H0YJF2 P51948
		NCBI	4331
		KEGG metabolic	Basal transcription factors Nucleotide excision repair
28	GTF2H4	ENSG00000213780	general transcription factor IIH subunit 4
		UniProt	Q92759
		NCBI	2968
		KEGG metabolic	Basal transcription factors Nucleotide excision repair
28	GTF2A1	ENSG00000165417	general transcription factor IIA subunit 1
		UniProt	J3KNC0 P52655
		NCBI	2957
		KEGG metabolic	Basal transcription factors
29	POLR2I	ENSG00000105258	RNA polymerase II subunit I
		UniProt	K7EK49 K7EKS1 K7ENX4 P36954
		NCBI	5438
		KEGG metabolic	RNA polymerase
30	POLR2B	ENSG00000047315	RNA polymerase II subunit B
		UniProt	A0A1W2PPT5 C9J2Y9 C9J4M6 C9JMN3 C9JZW8 P30876
		NCBI	5431
		KEGG metabolic	RNA polymerase
30	CCNH	ENSG00000134480	cyclin H
		UniProt	A0A2R8Y4K6 A0A2R8YEM2 D6RG18 D6RHI7 P51946
		NCBI	902
		KEGG signaling	Cell cycle
		KEGG metabolic	Basal transcription factors Nucleotide excision repair
30	GTF2H1	ENSG00000110768	general transcription factor IIH subunit 1
		UniProt	E9PI26 E9PL58 E9PM51 F5H0Y9 P32780
		NCBI	2965
		KEGG metabolic	Basal transcription factors Nucleotide excision repair
27	POLR2J2	ENSG00000228049	RNA polymerase II subunit J2
		UniProt	A6NFM0 Q9GZM3
		NCBI	246721 548644
		KEGG metabolic	RNA polymerase
24	GTF2H5	ENSG00000272047	general transcription factor IIH subunit 5
		UniProt	A0A3B3ISL4 Q6ZYL4
		NCBI	404672
		KEGG metabolic	Basal transcription factors Nucleotide excision repair
29	POLR2J	ENSG00000005075	RNA polymerase II subunit J
		UniProt	F6S314 P52435
		NCBI	5439
		KEGG metabolic	RNA polymerase
29	POLR2C	ENSG00000102978	RNA polymerase II subunit C
		UniProt	H3BRR2 P19387
		NCBI	5432
		KEGG metabolic	RNA polymerase
30	GTF2H2	ENSG00000145736	general transcription factor IIH subunit 2
		UniProt	D6RAW1 D6RGC9 Q13888 R4GMS9 R4GMV2
		NCBI	2966 728340 730394
		KEGG metabolic	Basal transcription factors Nucleotide excision repair
21	RPA1	ENSG00000132383	replication protein A1
		UniProt	I3L2M5 I3L4R8 I3L524 P27694
		NCBI	6117
		KEGG metabolic	DNA replication Fanconi anemia pathway Homologous recombination Mismatch repair Nucleotide excision repair
19	RPA2	ENSG00000117748	replication protein A2
		UniProt	P15927 Q5TEJ0 Q5TEJ7
		NCBI	6118
		KEGG metabolic	DNA replication Fanconi anemia pathway Homologous recombination Mismatch repair Nucleotide excision repair
28	ERCC2	ENSG00000104884	ERCC excision repair 2, TFIIH core complex helicase subunit
		UniProt	A8MX75 B4E0F6 E7EVE9 K7EIT8 K7EKF3 K7ENL1 P18074
		NCBI	2068
		KEGG metabolic	Basal transcription factors Nucleotide excision repair
30	GTF2B	ENSG00000137947	general transcription factor IIB
		UniProt	B1APE1 B1APE2 Q00403
		NCBI	2959
		KEGG metabolic	Basal transcription factors
17	ERCC5	ENSG00000134899	ERCC excision repair 5, endonuclease
		UniProt	A0A090HNM7 A0A494C0S2 A0A494C113 F2Z2A1 P28715 R4GMW8
		NCBI	2073
		KEGG metabolic	Nucleotide excision repair
26	TBPL2	ENSG00000182521	TATA-box binding protein like 2
		UniProt	G3V454 Q6SJ96
		NCBI	387332
		KEGG metabolic	Basal transcription factors
29	ERCC3	ENSG00000163161	ERCC excision repair 3, TFIIH core complex helicase subunit
		UniProt	A0A2R8Y4R8 A0A2R8Y5H0 A0A2R8Y5L2 A0A2R8Y681 A0A2R8Y6W8 A0A2R8Y762 A0A2R8YES7 A0A2R8YFS3 F2Z2V4 H7C309 P19447
		NCBI	2071
		KEGG metabolic	Basal transcription factors Nucleotide excision repair
29	POLR2G	ENSG00000168002	RNA polymerase II subunit G
		UniProt	E9PIU7 E9PKH3 E9PS03 H0YEE4 P62487
		NCBI	5436
		KEGG metabolic	RNA polymerase
27	POLR2J3	ENSG00000168255	RNA polymerase II subunit J3
		UniProt	A0A0B4J1Z8 A0A0B4J2F8 E2QRJ6 E7EP90 E7EWC6 F8WF84 Q9H1A7
		NCBI	548644
		KEGG metabolic	RNA polymerase
29	TBP	ENSG00000112592	TATA-box binding protein
		UniProt	A0A1B0GVC6 H0Y6D8 P20226 Q32MN6 Q7Z6S4 Q7Z6S5
		NCBI	6908
		KEGG metabolic	Basal transcription factors
30	GTF2H2C	ENSG00000183474	GTF2H2 family member C
		UniProt	D6RAW1 D6RGC9 D6RID8 D6RIT7 D6RJD3 Q6P1K8
		NCBI	2966 728340 730394
		KEGG metabolic	Basal transcription factors Nucleotide excision repair
30	CDK7	ENSG00000134058	cyclin dependent kinase 7
		UniProt	D6R9G1 D6R9Z2 D6RAD4 D6REC6 D6RF14 D6RFL0 D6RGG9 D6RI01 D6RIG9 P50613
		NCBI	1022
		KEGG signaling	Cell cycle
		KEGG metabolic	Basal transcription factors Nucleotide excision repair
30	TAF5	ENSG00000148835	TATA-box binding protein associated factor 5
		UniProt	Q15542
		NCBI	6877
		KEGG metabolic	Basal transcription factors
27	TAF7	ENSG00000178913	TATA-box binding protein associated factor 7
		UniProt	A0A096LPC3 Q15545
		NCBI	6879
		KEGG metabolic	Basal transcription factors

Enrichment analysis

Search for enrichment of pathways or functional gene sets for your subnetwork genes

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	jSquid_subnetworks.xml	322.51 KB
	H.sapiens_subnetwork.tsv	78.44 KB

Species:

Network information:

Filter Results:

Network appearance:

ENSG00000111358

TAF6

GTF2E2

GTF2E1

TAF2

MNAT1

GTF2H4

GTF2A1

POLR2I

POLR2B

CCNH

GTF2H1

POLR2J2

GTF2H5

POLR2J

POLR2C

GTF2H2

RPA1

RPA2

ERCC2

GTF2B

ERCC5

TBPL2

ERCC3

POLR2G

POLR2J3

TBP

GTF2H2C

CDK7

TAF5

TAF7

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