- Interaction partners
- Confidence
- Network
- Evidence types
- SpeciesHSAMMURNOCFAGGADRECINDMECELBTASCEATHSPOBSUECOPFADDISSOSSCMJAOSA
- In Gold st.
- ID Query gene
- ID Query ortholog
Log-likelihood ratio (LLR) | |
---|---|
Highly positive | |
Positive | |
Zero | |
Negative | |
Highly negative | |
Known coupling | |
This network | |
Other network |
-
- ENSG00000104133
- SPG11 vesicle trafficki…
- UPF1
- UPF1 RNA helicase and A…
- 0.997
- Complex
- HEATR5B
- HEAT repeat containing …
- 0.990
- PPI
- CLTC
- clathrin heavy chain
- 0.979
- Metabolic
- RAB8A
- RAB8A, member RAS oncog…
- 0.978
- PPI
- MTOR
- mechanistic target of r…
- 0.974
- Metabolic
- DNAJC13
- DnaJ heat shock protein…
- 0.973
- Complex
- CARMIL1
- capping protein regulat…
- 0.956
- Complex
- SNRNP70
- small nuclear ribonucle…
- 0.952
- Complex
- USP24
- ubiquitin specific pept…
- 0.940
- Complex
- VPS13A
- vacuolar protein sortin…
- 0.938
- Metabolic
- AP2A2
- adaptor related protein…
- 0.938
- Metabolic
- ARFGEF2
- ADP ribosylation factor…
- 0.934
- Metabolic
- ATP6V0A1
- ATPase H+ transporting …
- 0.933
- Metabolic
- UBA1
- ubiquitin like modifier…
- 0.922
- Complex
- AP2A1
- adaptor related protein…
- 0.920
- Metabolic
- WDFY3
- WD repeat and FYVE doma…
- 0.917
- Metabolic
- COPA
- COPI coat complex subun…
- 0.913
- Metabolic
- AP2B1
- adaptor related protein…
- 0.898
- Metabolic
- AP3B1
- adaptor related protein…
- 0.898
- Metabolic
- ZFYVE26
- zinc finger FYVE-type c…
- 0.896
- Metabolic
- SLC12A4
- solute carrier family 1…
- 0.891
- Metabolic
- STAG2
- stromal antigen 2
- 0.884
- Metabolic
- VPS11
- VPS11 core subunit of C…
- 0.879
- Complex
- RAB10
- RAB10, member RAS oncog…
- 0.875
- Complex
- ATP8A1
- ATPase phospholipid tra…
- 0.873
- Metabolic
- DDOST
- dolichyl-diphosphooligo…
- 0.868
- Metabolic
- TPR
- translocated promoter r…
- 0.867
- Metabolic
- TMEM63A
- transmembrane protein 6…
- 0.865
- Complex
- VPS39
- VPS39 subunit of HOPS c…
- 0.865
- Complex
- ATM
- ATM serine/threonine ki…
- 0.865
- Metabolic
ENSG00000104133
SPG11 vesicle trafficking associated, spatacsin
- Use as query
- Use pair as query
- Add to current query
- Ensembl
- UniProt
- NCBI
ZFYVE26
zinc finger FYVE-type containing 26
- Use as query
- Use pair as query
- Add to current query
- Ensembl
- UniProt
- NCBI
MTOR
mechanistic target of rapamycin kinase
- Use as query
- Use pair as query
- Add to current query
- Ensembl
- UniProt
- NCBI
VPS13A
vacuolar protein sorting 13 homolog A
- Use as query
- Use pair as query
- Add to current query
- Ensembl
- UniProt
- NCBI
RAB10
RAB10, member RAS oncogene family
- Use as query
- Use pair as query
- Add to current query
- Ensembl
- UniProt
- NCBI
STAG2
stromal antigen 2
- Use as query
- Use pair as query
- Add to current query
- Ensembl
- UniProt
- NCBI
AP2A1
adaptor related protein complex 2 subunit alpha 1
- Use as query
- Use pair as query
- Add to current query
- Ensembl
- UniProt
- NCBI
VPS11
VPS11 core subunit of CORVET and HOPS complexes
- Use as query
- Use pair as query
- Add to current query
- Ensembl
- UniProt
- NCBI
COPA
COPI coat complex subunit alpha
- Use as query
- Use pair as query
- Add to current query
- Ensembl
- UniProt
- A0A3B3IS23
- A0A3B3IS84
- A0A3B3ISC6
- A0A3B3ISK1
- A0A3B3IT15
- A0A3B3ITI7
- A0A3B3ITV3
- A0A3B3ITX2
- A0A3B3IU78
- A0A3B3IU84
- A0A3B3IU89
- P53621
- NCBI
ATM
ATM serine/threonine kinase
- Use as query
- Use pair as query
- Add to current query
- Ensembl
- UniProt
- NCBI
ATP6V0A1
ATPase H+ transporting V0 subunit a1
- Use as query
- Use pair as query
- Add to current query
- Ensembl
- UniProt
- NCBI
VPS39
VPS39 subunit of HOPS complex
- Use as query
- Use pair as query
- Add to current query
- Ensembl
- UniProt
- NCBI
AP3B1
adaptor related protein complex 3 subunit beta 1
- Use as query
- Use pair as query
- Add to current query
- Ensembl
- UniProt
- NCBI
AP2A2
adaptor related protein complex 2 subunit alpha 2
- Use as query
- Use pair as query
- Add to current query
- Ensembl
- UniProt
- NCBI
ARFGEF2
ADP ribosylation factor guanine nucleotide exchange factor 2
- Use as query
- Use pair as query
- Add to current query
- Ensembl
- UniProt
- NCBI
TMEM63A
transmembrane protein 63A
- Use as query
- Use pair as query
- Add to current query
- Ensembl
- UniProt
- NCBI
UPF1
UPF1 RNA helicase and ATPase
- Use as query
- Use pair as query
- Add to current query
- Ensembl
- UniProt
- NCBI
HEATR5B
HEAT repeat containing 5B
- Use as query
- Use pair as query
- Add to current query
- Ensembl
- UniProt
- NCBI
CARMIL1
capping protein regulator and myosin 1 linker 1
- Use as query
- Use pair as query
- Add to current query
- Ensembl
- UniProt
- NCBI
DDOST
dolichyl-diphosphooligosaccharide--protein glycosyltransferase non-catalytic subunit
- Use as query
- Use pair as query
- Add to current query
- Ensembl
- UniProt
- NCBI
DNAJC13
DnaJ heat shock protein family (Hsp40) member C13
- Use as query
- Use pair as query
- Add to current query
- Ensembl
- UniProt
- NCBI
UBA1
ubiquitin like modifier activating enzyme 1
- Use as query
- Use pair as query
- Add to current query
- Ensembl
- UniProt
- NCBI
SNRNP70
small nuclear ribonucleoprotein U1 subunit 70
- Use as query
- Use pair as query
- Add to current query
- Ensembl
- UniProt
- NCBI
ATP8A1
ATPase phospholipid transporting 8A1
- Use as query
- Use pair as query
- Add to current query
- Ensembl
- UniProt
- NCBI
CLTC
clathrin heavy chain
- Use as query
- Use pair as query
- Add to current query
- Ensembl
- UniProt
- NCBI
SLC12A4
solute carrier family 12 member 4
- Use as query
- Use pair as query
- Add to current query
- Ensembl
- UniProt
- NCBI
TPR
translocated promoter region, nuclear basket protein
- Use as query
- Use pair as query
- Add to current query
- Ensembl
- UniProt
- NCBI
USP24
ubiquitin specific peptidase 24
- Use as query
- Use pair as query
- Add to current query
- Ensembl
- UniProt
- NCBI
AP2B1
adaptor related protein complex 2 subunit beta 1
- Use as query
- Use pair as query
- Add to current query
- Ensembl
- UniProt
- A0A087WU93
- A0A087WXS3
- A0A087WYD1
- A0A087WZQ6
- A0A087X253
- K7EJ01
- K7EJX1
- K7EKZ5
- K7EMN7
- K7EN71
- K7ERB2
- P63010
- NCBI
RAB8A
RAB8A, member RAS oncogene family
- Use as query
- Use pair as query
- Add to current query
- Ensembl
- UniProt
- NCBI
WDFY3
WD repeat and FYVE domain containing 3
- Use as query
- Use pair as query
- Add to current query
- Ensembl
- UniProt
- NCBI
Symbol | Identifier | Description | |||
---|---|---|---|---|---|
16
|
ZFYVE26 | ENSG00000072121 | zinc finger FYVE-type containing 26 | ||
| A0A2H2FF08 G3V230 G3V2D8 Q68DK2 | ||||
| 23503 | ||||
29
|
MTOR | ENSG00000198793 | mechanistic target of rapamycin kinase | ||
| B1AKP8 B1AKQ2 P42345 | ||||
| 2475 | ||||
| Adipocytokine signaling pathway JAK-STAT signaling pathway ErbB signaling pathway Thyroid hormone signaling pathway HIF-1 signaling pathway AMPK signaling pathway PI3K-Akt signaling pathway Apelin signaling pathway mTOR signaling pathway Phospholipase D signaling pathway Insulin signaling pathway | ||||
| Autophagy - animal | ||||
24
|
VPS13A | ENSG00000197969 | vacuolar protein sorting 13 homolog A | ||
| H0Y7P8 H0YF78 H0YG53 Q96RL7 | ||||
| 23230 | ||||
16
|
RAB10 | ENSG00000084733 | RAB10, member RAS oncogene family | ||
| P61026 | ||||
| 10890 | ||||
| AMPK signaling pathway | ||||
| Endocytosis | ||||
21
|
STAG2 | ENSG00000101972 | stromal antigen 2 | ||
| B1AMS8 B1AMS9 B1AMT0 B1AMT1 B1AMT2 B1AMT3 B1AMT4 E7ERE6 Q8N3U4 | ||||
| 10735 | ||||
| Cell cycle | ||||
23
|
AP2A1 | ENSG00000196961 | adaptor related protein complex 2 subunit alpha 1 | ||
| M0R2D9 O95782 | ||||
| 160 | ||||
| Synaptic vesicle cycle | ||||
| Endocytosis | ||||
20
|
VPS11 | ENSG00000160695 | VPS11 core subunit of CORVET and HOPS complexes | ||
| A0A087WXL6 A0A087X2J4 B7Z879 Q9H270 | ||||
| 55823 | ||||
24
|
COPA | ENSG00000122218 | COPI coat complex subunit alpha | ||
| A0A3B3IS23 A0A3B3IS84 A0A3B3ISC6 A0A3B3ISK1 A0A3B3IT15 A0A3B3ITI7 A0A3B3ITV3 A0A3B3ITX2 A0A3B3IU78 A0A3B3IU84 A0A3B3IU89 P53621 | ||||
| 1314 | ||||
12
|
ATM | ENSG00000149311 | ATM serine/threonine kinase | ||
| A0A087X0E9 E9PIN0 E9PIQ5 E9PRG7 H0YDU7 H0YEC6 M0QXY8 Q13315 Q6P7P1 | ||||
| 472 | ||||
| p53 signaling pathway FoxO signaling pathway Apoptosis Cell cycle NF-kappa B signaling pathway | ||||
| Homologous recombination | ||||
24
|
ATP6V0A1 | ENSG00000033627 | ATPase H+ transporting V0 subunit a1 | ||
| B7Z2A9 B7Z641 F5H1T6 K7ELZ6 K7EM24 K7EN36 K7ENA1 K7EPG4 K7EQW2 K7ERA0 K7ERA6 Q93050 | ||||
| 535 | ||||
| Synaptic vesicle cycle | ||||
| Oxidative phosphorylation Phagosome Lysosome | ||||
24
|
VPS39 | ENSG00000166887 | VPS39 subunit of HOPS complex | ||
| H3BTU0 Q96JC1 | ||||
| 23339 | ||||
24
|
AP3B1 | ENSG00000132842 | adaptor related protein complex 3 subunit beta 1 | ||
| H0YBD0 O00203 | ||||
| 8546 | ||||
| Lysosome | ||||
24
|
AP2A2 | ENSG00000183020 | adaptor related protein complex 2 subunit alpha 2 | ||
| E9PNC4 E9PPY8 E9PPZ3 E9PQP4 E9PR62 E9PS94 H0YDE9 H0YEG0 O94973 | ||||
| 161 | ||||
| Synaptic vesicle cycle | ||||
| Endocytosis | ||||
25
|
ARFGEF2 | ENSG00000124198 | ADP ribosylation factor guanine nucleotide exchange factor 2 | ||
| Q9Y6D5 | ||||
| 10564 | ||||
| Endocytosis | ||||
20
|
TMEM63A | ENSG00000196187 | transmembrane protein 63A | ||
| O94886 Q2HIZ8 X6RI56 | ||||
| 9725 | ||||
19
|
UPF1 | ENSG00000005007 | UPF1 RNA helicase and ATPase | ||
| Q92900 | ||||
| 5976 | ||||
| RNA transport mRNA surveillance pathway | ||||
24
|
HEATR5B | ENSG00000008869 | HEAT repeat containing 5B | ||
| H7C2X3 Q9P2D3 | ||||
| 54497 | ||||
8
|
CARMIL1 | ENSG00000079691 | capping protein regulator and myosin 1 linker 1 | ||
| A0A0U1RQQ1 A0A0U1RR91 Q5VZK9 | ||||
| 55604 | ||||
26
|
DDOST | ENSG00000244038 | dolichyl-diphosphooligosaccharide--protein glycosyltransferase non-catalytic subunit | ||
| A0A0C4DGS1 P39656 U3KQ84 | ||||
| 1650 | ||||
| N-Glycan biosynthesis Various types of N-glycan biosynthesis Protein processing in endoplasmic reticulum | ||||
25
|
DNAJC13 | ENSG00000138246 | DnaJ heat shock protein family (Hsp40) member C13 | ||
| A0A3B3IRM0 H0Y8Q2 H0YA63 O75165 | ||||
| 23317 | ||||
28
|
UBA1 | ENSG00000130985 | ubiquitin like modifier activating enzyme 1 | ||
| P22314 Q5JRR6 Q5JRR9 Q5JRS0 Q5JRS1 Q5JRS2 Q5JRS3 | ||||
| 7317 | ||||
| Ubiquitin mediated proteolysis | ||||
5
|
SNRNP70 | ENSG00000104852 | small nuclear ribonucleoprotein U1 subunit 70 | ||
| M0QX04 M0QYR1 P08621 | ||||
| 6625 | ||||
| Spliceosome | ||||
21
|
ATP8A1 | ENSG00000124406 | ATPase phospholipid transporting 8A1 | ||
| H0Y8I6 H0YAA1 H0YAF4 H0YAJ4 Q4G1C1 Q9Y2Q0 | ||||
| 10396 | ||||
28
|
CLTC | ENSG00000141367 | clathrin heavy chain | ||
| A0A087WVQ6 J3KRF5 J3KS13 J3KSQ2 J3KTN1 J3QL20 K7EJJ5 Q00610 | ||||
| 1213 | ||||
| Synaptic vesicle cycle | ||||
| Endocytosis Lysosome | ||||
15
|
SLC12A4 | ENSG00000124067 | solute carrier family 12 member 4 | ||
| I3L1N8 I3L4N6 J3QKM4 J3QRE2 J3QSF2 Q9UP95 | ||||
| 6560 | ||||
17
|
TPR | ENSG00000047410 | translocated promoter region, nuclear basket protein | ||
| P12270 Q5SWX9 | ||||
| 7175 | ||||
| RNA transport | ||||
6
|
USP24 | ENSG00000162402 | ubiquitin specific peptidase 24 | ||
| A0A0U1RQI9 A0A0U1RRH2 Q9UPU5 | ||||
| 23358 | ||||
26
|
AP2B1 | ENSG00000006125 | adaptor related protein complex 2 subunit beta 1 | ||
| A0A087WU93 A0A087WXS3 A0A087WYD1 A0A087WZQ6 A0A087X253 K7EJ01 K7EJX1 K7EKZ5 K7EMN7 K7EN71 K7ERB2 P63010 | ||||
| 163 | ||||
| Synaptic vesicle cycle | ||||
| Endocytosis | ||||
16
|
RAB8A | ENSG00000167461 | RAB8A, member RAS oncogene family | ||
| P61006 | ||||
| 4218 | ||||
| Tight junction AMPK signaling pathway | ||||
| Endocytosis Autophagy - animal | ||||
16
|
WDFY3 | ENSG00000163625 | WD repeat and FYVE domain containing 3 | ||
| A0A1D5RMR8 D6RJE4 H0Y9T6 H0YAD8 Q8IZQ1 | ||||
| 23001 |
Search for enrichment of pathways or functional gene sets for your subnetwork genes | ||
To use PathwAX, first use the button below to copy the subnetwork genes and then paste them in PathwAX | ||
- Use as query
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jSquid_subnetworks.xml | 304.94 KB | |
H.sapiens_subnetwork.tsv | 58.87 KB |