Found 1 of 1 query genes

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Query interactions

Interaction partners
Confidence
Network
MEX
PIN
SCL
PHP
MIR
TFB
PEX
GIN
DOM
QMS
GRG
Evidence types
HSA
MMU
RNO
CFA
GGA
DRE
CIN
DME
CEL
BTA
SCE
ATH
SPO
BSU
ECO
PFA
DDI
SSO
SSC
MJA
OSA
Species
In Gold st.

ID Query gene
ID Query ortholog

Log-likelihood ratio (LLR)
	Highly positive
	Positive
	Zero
	Negative
	Highly negative
Known coupling
	This network
	Other network

2. ENSG00000099246
3. RAB18, member RAS oncog…
- 2. RAB6A
  3. RAB6A, member RAS oncog…
  4. 0.999
  5. Metabolic
- 2. GDI1
  3. GDP dissociation inhibi…
  4. 0.999
  5. PPI
- 2. RAB2B
  3. RAB2B, member RAS oncog…
  4. 0.999
  5. PPI
- 2. PPP2R1A
  3. protein phosphatase 2 s…
  4. 0.998
  5. PPI
- 2. SRPRB
  3. SRP receptor subunit be…
  4. 0.998
  5. PPI
- 2. CUL3
  3. cullin 3
  4. 0.998
  5. PPI
- 2. TMED2
  3. transmembrane p24 traff…
  4. 0.996
  5. Metabolic
- 2. COPB1
  3. COPI coat complex subun…
  4. 0.996
  5. Metabolic
- 2. RAB7A
  3. RAB7A, member RAS oncog…
  4. 0.994
  5. Metabolic
- 2. EGFR
  3. epidermal growth factor…
  4. 0.994
  5. PPI
- 2. TOM1L1
  3. target of myb1 like 1 m…
  4. 0.992
  5. PPI
- 2. RAC1
  3. Rac family small GTPase…
  4. 0.992
  5. Metabolic
- 2. PKM
  3. pyruvate kinase M1/2
  4. 0.991
  5. Complex
- 2. RAB11A
  3. RAB11A, member RAS onco…
  4. 0.989
  5. Metabolic
- 2. DDOST
  3. dolichyl-diphosphooligo…
  4. 0.986
  5. Metabolic
- 2. PSMA2
  3. proteasome 20S subunit …
  4. 0.985
  5. Metabolic
- 2. SAR1B
  3. secretion associated Ra…
  4. 0.985
  5. Metabolic
- 2. KDELR2
  3. KDEL endoplasmic reticu…
  4. 0.984
  5. Metabolic
- 2. GNAI3
  3. G protein subunit alpha…
  4. 0.981
  5. Metabolic
- 2. RAB5C
  3. RAB5C, member RAS oncog…
  4. 0.980
  5. Metabolic
- 2. TMEM30A
  3. transmembrane protein 3…
  4. 0.979
  5. Metabolic
- 2. VAMP7
  3. vesicle associated memb…
  4. 0.977
  5. Metabolic
- 2. AP1M1
  3. adaptor related protein…
  4. 0.977
  5. Metabolic
- 2. PSMD6
  3. proteasome 26S subunit,…
  4. 0.974
  5. Metabolic
- 2. CSNK1A1
  3. casein kinase 1 alpha 1
  4. 0.974
  5. PPI
- 2. RAB10
  3. RAB10, member RAS oncog…
  4. 0.974
  5. Metabolic
- 2. RAB5B
  3. RAB5B, member RAS oncog…
  4. 0.973
  5. Metabolic
- 2. VCP
  3. valosin containing prot…
  4. 0.973
  5. Metabolic
- 2. RAP1B
  3. RAP1B, member of RAS on…
  4. 0.973
  5. Metabolic
- 2. DNM1L
  3. dynamin 1 like
  4. 0.972
  5. Complex

Subnetwork gene interactions

ENSG00000099246

RAB18, member RAS oncogene family

FunCoup

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Ensembl

ENSG00000099246

UniProt

NCBI

22931

DDOST

dolichyl-diphosphooligosaccharide--protein glycosyltransferase non-catalytic subunit

FunCoup

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Ensembl

ENSG00000244038

UniProt

NCBI

1650

RAB5B

RAB5B, member RAS oncogene family

FunCoup

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Ensembl

ENSG00000111540

UniProt

NCBI

5869

PPP2R1A

protein phosphatase 2 scaffold subunit Aalpha

FunCoup

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Ensembl

ENSG00000105568

UniProt

NCBI

5518

PKM

pyruvate kinase M1/2

FunCoup

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Ensembl

ENSG00000067225

UniProt

NCBI

5315

KDELR2

KDEL endoplasmic reticulum protein retention receptor 2

FunCoup

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Ensembl

ENSG00000136240

UniProt

NCBI

11014

RAC1

Rac family small GTPase 1

FunCoup

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Ensembl

ENSG00000136238

UniProt

P63000

NCBI

5879

AP1M1

adaptor related protein complex 1 subunit mu 1

FunCoup

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Ensembl

ENSG00000072958

UniProt

NCBI

8907

COPB1

COPI coat complex subunit beta 1

FunCoup

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Ensembl

ENSG00000129083

UniProt

NCBI

1315

SRPRB

SRP receptor subunit beta

FunCoup

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Ensembl

ENSG00000144867

UniProt

NCBI

58477

PSMA2

proteasome 20S subunit alpha 2

FunCoup

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Ensembl

ENSG00000106588

UniProt

NCBI

5683

VAMP7

vesicle associated membrane protein 7

FunCoup

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Ensembl

ENSG00000124333

UniProt

NCBI

6845

EGFR

epidermal growth factor receptor

FunCoup

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Ensembl

ENSG00000146648

UniProt

NCBI

1956

TOM1L1

target of myb1 like 1 membrane trafficking protein

FunCoup

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Ensembl

ENSG00000141198

UniProt

NCBI

10040

VCP

valosin containing protein

FunCoup

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Ensembl

ENSG00000165280

UniProt

NCBI

7415

DNM1L

dynamin 1 like

FunCoup

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Ensembl

ENSG00000087470

UniProt

NCBI

10059

TMEM30A

transmembrane protein 30A

FunCoup

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Ensembl

ENSG00000112697

UniProt

NCBI

55754

SAR1B

secretion associated Ras related GTPase 1B

FunCoup

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Ensembl

ENSG00000152700

UniProt

NCBI

51128

RAP1B

RAP1B, member of RAS oncogene family

FunCoup

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Ensembl

ENSG00000127314

UniProt

NCBI

5908

RAB10

RAB10, member RAS oncogene family

FunCoup

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Ensembl

ENSG00000084733

UniProt

P61026

NCBI

10890

PSMD6

proteasome 26S subunit, non-ATPase 6

FunCoup

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Ensembl

ENSG00000163636

UniProt

NCBI

9861

RAB6A

RAB6A, member RAS oncogene family

FunCoup

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Ensembl

ENSG00000175582

UniProt

NCBI

5870

GDI1

GDP dissociation inhibitor 1

FunCoup

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Ensembl

ENSG00000203879

UniProt

NCBI

2664

CUL3

cullin 3

FunCoup

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Ensembl

ENSG00000036257

UniProt

NCBI

8452

GNAI3

G protein subunit alpha i3

FunCoup

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Ensembl

ENSG00000065135

UniProt

P08754

NCBI

2773

RAB2B

RAB2B, member RAS oncogene family

FunCoup

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Ensembl

ENSG00000129472

UniProt

NCBI

84932

RAB5C

RAB5C, member RAS oncogene family

FunCoup

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Ensembl

ENSG00000108774

UniProt

NCBI

5878

RAB7A

RAB7A, member RAS oncogene family

FunCoup

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Ensembl

ENSG00000075785

UniProt

NCBI

7879

TMED2

transmembrane p24 trafficking protein 2

FunCoup

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Ensembl

ENSG00000086598

UniProt

NCBI

10959

RAB11A

RAB11A, member RAS oncogene family

FunCoup

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Ensembl

ENSG00000103769

UniProt

NCBI

8766

CSNK1A1

casein kinase 1 alpha 1

FunCoup

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Ensembl

ENSG00000113712

UniProt

NCBI

1452

Query genes

		Identifier	Description
30	ENSG00000099246	ENSG00000099246	RAB18, member RAS oncogene family
		UniProt	A0A087X163 H0Y6T8 Q5W0J0 Q9NP72
		NCBI	22931

Subnetwork genes

		Identifier	Description
26	DDOST	ENSG00000244038	dolichyl-diphosphooligosaccharide--protein glycosyltransferase non-catalytic subunit
		UniProt	A0A0C4DGS1 P39656 U3KQ84
		NCBI	1650
		KEGG metabolic	N-Glycan biosynthesis Various types of N-glycan biosynthesis Protein processing in endoplasmic reticulum
27	RAB5B	ENSG00000111540	RAB5B, member RAS oncogene family
		UniProt	F8VPW9 F8VUA5 F8VVZ0 F8VWZ7 P61020
		NCBI	5869
		KEGG signaling	Ras signaling pathway
		KEGG metabolic	Phagosome Endocytosis
27	PPP2R1A	ENSG00000105568	protein phosphatase 2 scaffold subunit Aalpha
		UniProt	B3KQV6 C9J9C1 E9PH38 M0QXG4 M0R0K6 P30153
		NCBI	5518
		KEGG signaling	Oocyte meiosis Long-term depression Tight junction TGF-beta signaling pathway AMPK signaling pathway Dopaminergic synapse PI3K-Akt signaling pathway Adrenergic signaling in cardiomyocytes Hippo signaling pathway Sphingolipid signaling pathway
		KEGG metabolic	mRNA surveillance pathway
25	PKM	ENSG00000067225	pyruvate kinase M1/2
		UniProt	B4DNK4 H3BN34 H3BQ34 H3BQZ3 H3BR70 H3BT25 H3BTJ2 H3BTN5 H3BU13 H3BUW1 P14618
		NCBI	5315
		KEGG signaling	Glucagon signaling pathway
		KEGG metabolic	Pyruvate metabolism Glycolysis / Gluconeogenesis Purine metabolism Biosynthesis of amino acids Carbon metabolism
27	KDELR2	ENSG00000136240	KDEL endoplasmic reticulum protein retention receptor 2
		UniProt	H7BYF7 P33947
		NCBI	11014
27	RAC1	ENSG00000136238	Rac family small GTPase 1
		UniProt	P63000
		NCBI	5879
		KEGG signaling	MAPK signaling pathway Leukocyte transendothelial migration PI3K-Akt signaling pathway VEGF signaling pathway Chemokine signaling pathway Sphingolipid signaling pathway Neurotrophin signaling pathway Fc gamma R-mediated phagocytosis Toll-like receptor signaling pathway Focal adhesion Fc epsilon RI signaling pathway Rap1 signaling pathway Ras signaling pathway Adherens junction B cell receptor signaling pathway Wnt signaling pathway cAMP signaling pathway Tight junction Natural killer cell mediated cytotoxicity
		KEGG metabolic	Phagosome
27	AP1M1	ENSG00000072958	adaptor related protein complex 1 subunit mu 1
		UniProt	A0A087WZX7 E7ENJ6 K7EJL1 K7ENA7 K7EPJ8 K7EQ90 K7EQX3 K7ER75 Q9BXS5
		NCBI	8907
		KEGG metabolic	Lysosome
28	COPB1	ENSG00000129083	COPI coat complex subunit beta 1
		UniProt	E9PKQ1 E9PP63 E9PP73 P53618
		NCBI	1315
19	SRPRB	ENSG00000144867	SRP receptor subunit beta
		UniProt	C9J5Z8 H7C4H2 Q9Y5M8
		NCBI	58477
		KEGG metabolic	Protein export
26	PSMA2	ENSG00000106588	proteasome 20S subunit alpha 2
		UniProt	C9JCK5 F8WEG3 H7C3A7 H7C402 P25787
		NCBI	5683
		KEGG metabolic	Proteasome
26	VAMP7	ENSG00000124333	vesicle associated membrane protein 7
		UniProt	E5RH06 P51809
		NCBI	6845
		KEGG signaling	SNARE interactions in vesicular transport
		KEGG metabolic	SNARE interactions in vesicular transport
6	EGFR	ENSG00000146648	epidermal growth factor receptor
		UniProt	A0A1W2PRR9 C9JYS6 E9PFD7 P00533 Q504U8
		NCBI	1956
		KEGG signaling	MAPK signaling pathway Calcium signaling pathway PI3K-Akt signaling pathway Phospholipase D signaling pathway Rap1 signaling pathway Focal adhesion Adherens junction JAK-STAT signaling pathway Ras signaling pathway FoxO signaling pathway Gap junction ErbB signaling pathway HIF-1 signaling pathway Estrogen signaling pathway Relaxin signaling pathway GnRH signaling pathway Oxytocin signaling pathway
		KEGG metabolic	Endocytosis
9	TOM1L1	ENSG00000141198	target of myb1 like 1 membrane trafficking protein
		UniProt	I3L0N2 I3L1G1 I3L1Q1 I3L1T2 I3L367 I3L3M3 I3L3T4 I3L4G0 I3L4I4 I3L4N3 I3NI44 J3KQU4 K7EP47 O75674
		NCBI	10040
28	VCP	ENSG00000165280	valosin containing protein
		UniProt	C9IZA5 C9JUP7 P55072
		NCBI	7415
		KEGG metabolic	Protein processing in endoplasmic reticulum
27	DNM1L	ENSG00000087470	dynamin 1 like
		UniProt	B4DDQ3 B4DPZ9 F8VR28 F8VUJ9 F8VYL3 F8VZ52 F8W1W3 H0YHY4 H0YI79 O00429
		NCBI	10059
		KEGG signaling	NOD-like receptor signaling pathway TNF signaling pathway
24	TMEM30A	ENSG00000112697	transmembrane protein 30A
		UniProt	E5RG19 Q9NV96
		NCBI	55754
26	SAR1B	ENSG00000152700	secretion associated Ras related GTPase 1B
		UniProt	D6R9R5 D6RAA2 D6RD69 D6RDB2 Q9H029 Q9Y6B6
		NCBI	51128
		KEGG metabolic	Protein processing in endoplasmic reticulum
25	RAP1B	ENSG00000127314	RAP1B, member of RAS oncogene family
		UniProt	B7ZB78 E7ESV4 F5GWU8 F5GX62 F5GYB5 F5GYH7 F5GZG1 F5H004 F5H077 F5H0B7 F5H0S2 F5H491 F5H4H0 F5H500 F5H6R7 F5H7Y6 F5H823 F8WBC0 P61224
		NCBI	5908
		KEGG signaling	Neurotrophin signaling pathway Long-term potentiation Focal adhesion Rap1 signaling pathway Ras signaling pathway cAMP signaling pathway Leukocyte transendothelial migration MAPK signaling pathway Chemokine signaling pathway
27	RAB10	ENSG00000084733	RAB10, member RAS oncogene family
		UniProt	P61026
		NCBI	10890
		KEGG signaling	AMPK signaling pathway
		KEGG metabolic	Endocytosis
27	PSMD6	ENSG00000163636	proteasome 26S subunit, non-ATPase 6
		UniProt	C9J0E9 C9J7B7 H7C531 Q15008
		NCBI	9861
		KEGG metabolic	Proteasome
29	RAB6A	ENSG00000175582	RAB6A, member RAS oncogene family
		UniProt	F5GX61 F5H3K7 P20340
		NCBI	5870
25	GDI1	ENSG00000203879	GDP dissociation inhibitor 1
		UniProt	F8WCU0 F8WE59 G5E9U5 P31150
		NCBI	2664
26	CUL3	ENSG00000036257	cullin 3
		UniProt	A0A087WTG3 A0A087X1R9 H7C1J0 H7C1L6 H7C399 Q13618
		NCBI	8452
		KEGG signaling	Hedgehog signaling pathway
		KEGG metabolic	Ubiquitin mediated proteolysis
28	GNAI3	ENSG00000065135	G protein subunit alpha i3
		UniProt	P08754
		NCBI	2773
		KEGG signaling	Leukocyte transendothelial migration Apelin signaling pathway Adrenergic signaling in cardiomyocytes Chemokine signaling pathway Sphingolipid signaling pathway Rap1 signaling pathway Long-term depression cAMP signaling pathway Gap junction cGMP-PKG signaling pathway Melanogenesis Dopaminergic synapse Relaxin signaling pathway Estrogen signaling pathway Progesterone-mediated oocyte maturation GABAergic synapse Serotonergic synapse Cholinergic synapse Glutamatergic synapse Retrograde endocannabinoid signaling Oxytocin signaling pathway
12	RAB2B	ENSG00000129472	RAB2B, member RAS oncogene family
		UniProt	A0A3B3ITL1 E9PE37 Q8WUD1
		NCBI	84932
27	RAB5C	ENSG00000108774	RAB5C, member RAS oncogene family
		UniProt	F8VSF8 F8VVK3 F8VWU4 K7ENY4 P51148
		NCBI	5878
		KEGG signaling	Ras signaling pathway
		KEGG metabolic	Phagosome Endocytosis
27	RAB7A	ENSG00000075785	RAB7A, member RAS oncogene family
		UniProt	C9IZZ0 C9J4S4 C9J4V0 C9J592 C9J7D1 C9J8S3 P51149
		NCBI	7879
		KEGG metabolic	Phagosome Endocytosis Autophagy - animal
26	TMED2	ENSG00000086598	transmembrane p24 trafficking protein 2
		UniProt	E7EQ72 F5GX39 Q15363
		NCBI	10959
29	RAB11A	ENSG00000103769	RAB11A, member RAS oncogene family
		UniProt	B4DQU5 H3BMH2 H3BN38 H3BSC1 P62491
		NCBI	8766
		KEGG metabolic	Endocytosis
9	CSNK1A1	ENSG00000113712	casein kinase 1 alpha 1
		UniProt	A0A590UJ43 A0A590UJQ7 A0A590UK94 A0A5F9W493 D6REM4 D6RGE5 E5RG27 E7ETM0 H0Y9X2 P48729 U3KPX3 U3KQ83 U3KQK7
		NCBI	1452
		KEGG signaling	Wnt signaling pathway Hedgehog signaling pathway

Enrichment analysis

Search for enrichment of pathways or functional gene sets for your subnetwork genes

To use PathwAX, first use the button below to copy the subnetwork genes and then paste them in PathwAX

Copied subnetwork genes to clipboard

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	jSquid_subnetworks.xml	300.99 KB
	H.sapiens_subnetwork.tsv	73.43 KB

Species:

Network information:

Filter Results:

Network appearance:

ENSG00000099246

DDOST

RAB5B

PPP2R1A

PKM

KDELR2

RAC1

AP1M1

COPB1

SRPRB

PSMA2

VAMP7

EGFR

TOM1L1

VCP

DNM1L

TMEM30A

SAR1B

RAP1B

RAB10

PSMD6

RAB6A

GDI1

CUL3

GNAI3

RAB2B

RAB5C

RAB7A

TMED2

RAB11A

CSNK1A1

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