Found 1 of 1 query genes

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Query interactions

Interaction partners
Confidence
Network
MEX
PIN
SCL
PHP
MIR
TFB
PEX
GIN
DOM
QMS
GRG
Evidence types
HSA
MMU
RNO
CFA
GGA
DRE
CIN
DME
CEL
BTA
SCE
ATH
SPO
BSU
ECO
PFA
DDI
SSO
SSC
MJA
OSA
Species
In Gold st.

ID Query gene
ID Query ortholog

Log-likelihood ratio (LLR)
	Highly positive
	Positive
	Zero
	Negative
	Highly negative
Known coupling
	This network
	Other network

2. ENSG00000091164
3. thioredoxin like 1
- 2. PSMD6
  3. proteasome 26S subunit,…
  4. 1.000
  5. PPI
- 2. PSMC3
  3. proteasome 26S subunit,…
  4. 1.000
  5. PPI
- 2. PSMA1
  3. proteasome 20S subunit …
  4. 1.000
  5. PPI
- 2. PSMC1
  3. proteasome 26S subunit,…
  4. 1.000
  5. PPI
- 2. USP14
  3. ubiquitin specific pept…
  4. 1.000
  5. PPI
- 2. PSMD4
  3. proteasome 26S subunit,…
  4. 1.000
  5. PPI
- 2. RAD23A
  3. RAD23 homolog A, nucleo…
  4. 1.000
  5. PPI
- 2. UCHL5
  3. ubiquitin C-terminal hy…
  4. 1.000
  5. PPI
- 2. PSMD14
  3. proteasome 26S subunit,…
  4. 1.000
  5. Metabolic
- 2. PSMB4
  3. proteasome 20S subunit …
  4. 1.000
  5. Metabolic
- 2. PSMB2
  3. proteasome 20S subunit …
  4. 0.999
  5. Metabolic
- 2. PSMA2
  3. proteasome 20S subunit …
  4. 0.999
  5. Metabolic
- 2. UBE3A
  3. ubiquitin protein ligas…
  4. 0.999
  5. PPI
- 2. PSMA6
  3. proteasome 20S subunit …
  4. 0.999
  5. Metabolic
- 2. PSMC6
  3. proteasome 26S subunit,…
  4. 0.999
  5. Metabolic
- 2. PSMD12
  3. proteasome 26S subunit,…
  4. 0.999
  5. Metabolic
- 2. PSMC4
  3. proteasome 26S subunit,…
  4. 0.999
  5. Metabolic
- 2. PSMB1
  3. proteasome 20S subunit …
  4. 0.999
  5. Metabolic
- 2. PSMA3
  3. proteasome 20S subunit …
  4. 0.999
  5. Metabolic
- 2. PSMD8
  3. proteasome 26S subunit,…
  4. 0.998
  5. Complex
- 2. PSMB7
  3. proteasome 20S subunit …
  4. 0.998
  5. Metabolic
- 2. PSMB3
  3. proteasome 20S subunit …
  4. 0.998
  5. Metabolic
- 2. PSMD7
  3. proteasome 26S subunit,…
  4. 0.998
  5. Metabolic
- 2. PSMA4
  3. proteasome 20S subunit …
  4. 0.998
  5. Metabolic
- 2. PSMA5
  3. proteasome 20S subunit …
  4. 0.997
  5. Metabolic
- 2. PSMB5
  3. proteasome 20S subunit …
  4. 0.996
  5. Metabolic
- 2. PSMA7
  3. proteasome 20S subunit …
  4. 0.995
  5. Metabolic
- 2. PSMB6
  3. proteasome 20S subunit …
  4. 0.994
  5. Metabolic
- 2. UBE2N
  3. ubiquitin conjugating e…
  4. 0.994
  5. Metabolic
- 2. PSMD13
  3. proteasome 26S subunit,…
  4. 0.994
  5. Metabolic

Subnetwork gene interactions

ENSG00000091164

thioredoxin like 1

FunCoup

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Ensembl

ENSG00000091164

UniProt

NCBI

9352

USP14

ubiquitin specific peptidase 14

FunCoup

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Ensembl

ENSG00000101557

UniProt

NCBI

9097

UCHL5

ubiquitin C-terminal hydrolase L5

FunCoup

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Ensembl

ENSG00000116750

UniProt

NCBI

51377

PSMD6

proteasome 26S subunit, non-ATPase 6

FunCoup

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Ensembl

ENSG00000163636

UniProt

NCBI

9861

PSMC3

proteasome 26S subunit, ATPase 3

FunCoup

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Ensembl

ENSG00000165916

UniProt

NCBI

5702

PSMB5

proteasome 20S subunit beta 5

FunCoup

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Ensembl

ENSG00000100804

UniProt

NCBI

5693

PSMB3

proteasome 20S subunit beta 3

FunCoup

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Ensembl

ENSG00000277791

UniProt

NCBI

5691

PSMD4

proteasome 26S subunit, non-ATPase 4

FunCoup

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Ensembl

ENSG00000159352

UniProt

NCBI

5710

PSMD14

proteasome 26S subunit, non-ATPase 14

FunCoup

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Ensembl

ENSG00000115233

UniProt

NCBI

10213

PSMA1

proteasome 20S subunit alpha 1

FunCoup

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Ensembl

ENSG00000129084

UniProt

NCBI

5682

PSMA3

proteasome 20S subunit alpha 3

FunCoup

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Ensembl

ENSG00000100567

UniProt

NCBI

5684

PSMA7

proteasome 20S subunit alpha 7

FunCoup

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Ensembl

ENSG00000101182

UniProt

NCBI

5688

PSMB4

proteasome 20S subunit beta 4

FunCoup

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Ensembl

ENSG00000159377

UniProt

P28070

NCBI

5692

PSMD7

proteasome 26S subunit, non-ATPase 7

FunCoup

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Ensembl

ENSG00000103035

UniProt

NCBI

5713

PSMB7

proteasome 20S subunit beta 7

FunCoup

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Ensembl

ENSG00000136930

UniProt

NCBI

5695

PSMD13

proteasome 26S subunit, non-ATPase 13

FunCoup

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Ensembl

ENSG00000185627

UniProt

NCBI

5719

PSMD12

proteasome 26S subunit, non-ATPase 12

FunCoup

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Ensembl

ENSG00000197170

UniProt

NCBI

5718

PSMD8

proteasome 26S subunit, non-ATPase 8

FunCoup

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Ensembl

ENSG00000099341

UniProt

NCBI

5714

PSMB1

proteasome 20S subunit beta 1

FunCoup

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Ensembl

ENSG00000008018

UniProt

P20618

NCBI

5689

PSMA4

proteasome 20S subunit alpha 4

FunCoup

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Ensembl

ENSG00000041357

UniProt

NCBI

5685

PSMB2

proteasome 20S subunit beta 2

FunCoup

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Ensembl

ENSG00000126067

UniProt

NCBI

5690

UBE3A

ubiquitin protein ligase E3A

FunCoup

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Ensembl

ENSG00000114062

UniProt

NCBI

7337

UBE2N

ubiquitin conjugating enzyme E2 N

FunCoup

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Ensembl

ENSG00000177889

UniProt

NCBI

7334

PSMA6

proteasome 20S subunit alpha 6

FunCoup

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Ensembl

ENSG00000100902

UniProt

NCBI

5687

PSMB6

proteasome 20S subunit beta 6

FunCoup

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Ensembl

ENSG00000142507

UniProt

NCBI

5694

PSMA2

proteasome 20S subunit alpha 2

FunCoup

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Ensembl

ENSG00000106588

UniProt

NCBI

5683

PSMC6

proteasome 26S subunit, ATPase 6

FunCoup

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Ensembl

ENSG00000100519

UniProt

NCBI

5706

PSMC1

proteasome 26S subunit, ATPase 1

FunCoup

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Ensembl

ENSG00000100764

UniProt

NCBI

5700

PSMA5

proteasome 20S subunit alpha 5

FunCoup

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Ensembl

ENSG00000143106

UniProt

P28066

NCBI

5686

PSMC4

proteasome 26S subunit, ATPase 4

FunCoup

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Ensembl

ENSG00000013275

UniProt

P43686

NCBI

5704

RAD23A

RAD23 homolog A, nucleotide excision repair protein

FunCoup

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Ensembl

ENSG00000179262

UniProt

NCBI

5886

Query genes

		Identifier	Description
30	ENSG00000091164	ENSG00000091164	thioredoxin like 1
		UniProt	K7EKG2 K7EME7 K7EML9 K7EPB7 K7ER96 O43396
		NCBI	9352

Subnetwork genes

		Identifier	Description
30	USP14	ENSG00000101557	ubiquitin specific peptidase 14
		UniProt	A6NJA2 J3KS55 J3QQT6 P54578 R4GNB0
		NCBI	9097
29	UCHL5	ENSG00000116750	ubiquitin C-terminal hydrolase L5
		UniProt	H0Y4E0 H0Y4K0 H0Y636 H0Y6Y4 Q5LJA5 Q5LJA9 Q5LJB0 Q5LJB1 Q9Y5K5
		NCBI	51377
30	PSMD6	ENSG00000163636	proteasome 26S subunit, non-ATPase 6
		UniProt	C9J0E9 C9J7B7 H7C531 Q15008
		NCBI	9861
		KEGG metabolic	Proteasome
30	PSMC3	ENSG00000165916	proteasome 26S subunit, ATPase 3
		UniProt	E9PKD5 E9PLG2 E9PM69 E9PMD8 E9PMW0 E9PN50 E9PS45 P17980 R4GNH3
		NCBI	5702
		KEGG metabolic	Proteasome
29	PSMB5	ENSG00000100804	proteasome 20S subunit beta 5
		UniProt	G3V3K3 G8JLC2 H0YJM8 P28074
		NCBI	5693
		KEGG metabolic	Proteasome
29	PSMB3	ENSG00000277791	proteasome 20S subunit beta 3
		UniProt	A0A087WUL2 A0A087WXQ8 A0A087WY10 P49720
		NCBI	5691
		KEGG metabolic	Proteasome
30	PSMD4	ENSG00000159352	proteasome 26S subunit, non-ATPase 4
		UniProt	A6PVX3 H0Y3Y9 H0Y561 H7C2J9 P55036 Q5VWC4
		NCBI	5710
		KEGG metabolic	Proteasome
29	PSMD14	ENSG00000115233	proteasome 26S subunit, non-ATPase 14
		UniProt	C9JW37 O00487
		NCBI	10213
		KEGG metabolic	Proteasome
30	PSMA1	ENSG00000129084	proteasome 20S subunit alpha 1
		UniProt	F5GX11 F5H112 P25786
		NCBI	5682
		KEGG metabolic	Proteasome
30	PSMA3	ENSG00000100567	proteasome 20S subunit alpha 3
		UniProt	G3V3W4 G3V4X5 G3V5N4 H0YJ03 P25788
		NCBI	5684
		KEGG metabolic	Proteasome
29	PSMA7	ENSG00000101182	proteasome 20S subunit alpha 7
		UniProt	H0Y586 O14818
		NCBI	5688
		KEGG metabolic	Proteasome
29	PSMB4	ENSG00000159377	proteasome 20S subunit beta 4
		UniProt	P28070
		NCBI	5692
		KEGG metabolic	Proteasome
30	PSMD7	ENSG00000103035	proteasome 26S subunit, non-ATPase 7
		UniProt	H3BNT7 H3BQV2 H3BTM8 P51665
		NCBI	5713
		KEGG metabolic	Proteasome
30	PSMB7	ENSG00000136930	proteasome 20S subunit beta 7
		UniProt	Q5TBG5 Q99436
		NCBI	5695
		KEGG metabolic	Proteasome
30	PSMD13	ENSG00000185627	proteasome 26S subunit, non-ATPase 13
		UniProt	A0A087WUL9 E9PL38 E9PPD2 E9PQG3 F8W8J6 H0YD73 J3KNQ3 Q9UNM6
		NCBI	5719
		KEGG metabolic	Proteasome
30	PSMD12	ENSG00000197170	proteasome 26S subunit, non-ATPase 12
		UniProt	J3KSK1 J3KTJ5 O00232
		NCBI	5718
		KEGG metabolic	Proteasome
30	PSMD8	ENSG00000099341	proteasome 26S subunit, non-ATPase 8
		UniProt	K7EJC1 K7EJR3 K7EK21 K7ENY6 K7ERW6 P48556 R4GMR5
		NCBI	5714
		KEGG metabolic	Proteasome
29	PSMB1	ENSG00000008018	proteasome 20S subunit beta 1
		UniProt	P20618
		NCBI	5689
		KEGG metabolic	Proteasome
30	PSMA4	ENSG00000041357	proteasome 20S subunit alpha 4
		UniProt	H0YKS0 H0YKT8 H0YL69 H0YLC2 H0YLS6 H0YMA1 H0YMI6 H0YMV3 H0YMZ1 H0YN18 P25789
		NCBI	5685
		KEGG metabolic	Proteasome
30	PSMB2	ENSG00000126067	proteasome 20S subunit beta 2
		UniProt	A0A087WVV1 P49721
		NCBI	5690
		KEGG metabolic	Proteasome
21	UBE3A	ENSG00000114062	ubiquitin protein ligase E3A
		UniProt	A0A0D9SEJ2 A0A0D9SES7 A0A0D9SF91 A0A0D9SFH3 A0A0D9SFU3 A0A0D9SG54 A0A0D9SG63 A0A0D9SG77 A0A0G2JQQ5 A0A1B0GTB3 A0A1B0GVL3 Q05086 S4R306
		NCBI	7337
		KEGG metabolic	Ubiquitin mediated proteolysis
30	UBE2N	ENSG00000177889	ubiquitin conjugating enzyme E2 N
		UniProt	F8VQQ8 F8VSD4 F8VV71 F8VZ29 P61088
		NCBI	7334
		KEGG metabolic	Ubiquitin mediated proteolysis
30	PSMA6	ENSG00000100902	proteasome 20S subunit alpha 6
		UniProt	G3V295 G3V2S7 G3V3I1 G3V3U4 G3V4S5 G3V5Z7 H0YJC4 P60900
		NCBI	5687
		KEGG metabolic	Proteasome
30	PSMB6	ENSG00000142507	proteasome 20S subunit beta 6
		UniProt	A0A087X2I4 I3L3X7 P28072
		NCBI	5694
		KEGG metabolic	Proteasome
30	PSMA2	ENSG00000106588	proteasome 20S subunit alpha 2
		UniProt	C9JCK5 F8WEG3 H7C3A7 H7C402 P25787
		NCBI	5683
		KEGG metabolic	Proteasome
30	PSMC6	ENSG00000100519	proteasome 26S subunit, ATPase 6
		UniProt	A0A087X2I1 H0YJC0 H0YJD2 H0YJE9 H0YJS8 H0YJT1 H0YJW2 H0YJX2 H0YJY8 P62333
		NCBI	5706
		KEGG metabolic	Proteasome
30	PSMC1	ENSG00000100764	proteasome 26S subunit, ATPase 1
		UniProt	G3V4X1 P62191
		NCBI	5700
		KEGG metabolic	Proteasome
30	PSMA5	ENSG00000143106	proteasome 20S subunit alpha 5
		UniProt	P28066
		NCBI	5686
		KEGG metabolic	Proteasome
29	PSMC4	ENSG00000013275	proteasome 26S subunit, ATPase 4
		UniProt	P43686
		NCBI	5704
		KEGG metabolic	Proteasome
29	RAD23A	ENSG00000179262	RAD23 homolog A, nucleotide excision repair protein
		UniProt	A0A494C0B4 K7ELU6 K7ELW1 K7ENJ0 K7EQ16 P54725
		NCBI	5886
		KEGG metabolic	Protein processing in endoplasmic reticulum Nucleotide excision repair

Enrichment analysis

Search for enrichment of pathways or functional gene sets for your subnetwork genes

To use PathwAX, first use the button below to copy the subnetwork genes and then paste them in PathwAX

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	jSquid_subnetworks.xml	389.98 KB
	H.sapiens_subnetwork.tsv	90.37 KB

Species:

Network information:

Filter Results:

Network appearance:

ENSG00000091164

USP14

UCHL5

PSMD6

PSMC3

PSMB5

PSMB3

PSMD4

PSMD14

PSMA1

PSMA3

PSMA7

PSMB4

PSMD7

PSMB7

PSMD13

PSMD12

PSMD8

PSMB1

PSMA4

PSMB2

UBE3A

UBE2N

PSMA6

PSMB6

PSMA2

PSMC6

PSMC1

PSMA5

PSMC4

RAD23A

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