Found 1 of 1 query genes

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Query interactions

Interaction partners
Confidence
Network
MEX
PIN
SCL
PHP
MIR
TFB
PEX
GIN
DOM
QMS
GRG
Evidence types
HSA
MMU
RNO
CFA
GGA
DRE
CIN
DME
CEL
BTA
SCE
ATH
SPO
BSU
ECO
PFA
DDI
SSO
SSC
MJA
OSA
Species
In Gold st.

ID Query gene
ID Query ortholog

Log-likelihood ratio (LLR)
	Highly positive
	Positive
	Zero
	Negative
	Highly negative
Known coupling
	This network
	Other network

2. ENSG00000087111
3. phosphatidylinositol gl…
- 2. PIGT
  3. phosphatidylinositol gl…
  4. 1.000
  5. PPI
- 2. GPAA1
  3. glycosylphosphatidylino…
  4. 1.000
  5. PPI
- 2. PIGK
  3. phosphatidylinositol gl…
  4. 1.000
  5. PPI
- 2. PIGU
  3. phosphatidylinositol gl…
  4. 1.000
  5. PPI
- 2. NDUFA9
  3. NADH:ubiquinone oxidore…
  4. 0.999
  5. PPI
- 2. YIPF5
  3. Yip1 domain family memb…
  4. 0.998
  5. PPI
- 2. CERS5
  3. ceramide synthase 5
  4. 0.993
  5. PPI
- 2. EMC1
  3. ER membrane protein com…
  4. 0.988
  5. Metabolic
- 2. DNAJC8
  3. DnaJ heat shock protein…
  4. 0.988
  5. PPI
- 2. SF3B1
  3. splicing factor 3b subu…
  4. 0.984
  5. PPI
- 2. ACAP2
  3. ArfGAP with coiled-coil…
  4. 0.983
  5. PPI
- 2. CERS4
  3. ceramide synthase 4
  4. 0.983
  5. PPI
- 2. TECR
  3. trans-2,3-enoyl-CoA red…
  4. 0.975
  5. Metabolic
- 2. ERN1
  3. endoplasmic reticulum t…
  4. 0.974
  5. Metabolic
- 2. CERS6
  3. ceramide synthase 6
  4. 0.971
  5. PPI
- 2. VCP
  3. valosin containing prot…
  4. 0.970
  5. Metabolic
- 2. GPR89B
  3. G protein-coupled recep…
  4. 0.970
  5. PPI
- 2. FBXO6
  3. F-box protein 6
  4. 0.970
  5. PPI
- 2. RPN1
  3. ribophorin I
  4. 0.969
  5. Metabolic
- 2. TUSC3
  3. tumor suppressor candid…
  4. 0.966
  5. Metabolic
- 2. GPR89A
  3. G protein-coupled recep…
  4. 0.965
  5. PPI
- 2. MPDU1
  3. mannose-P-dolichol util…
  4. 0.964
  5. Metabolic
- 2. EMC4
  3. ER membrane protein com…
  4. 0.959
  5. Metabolic
- 2. CERS2
  3. ceramide synthase 2
  4. 0.957
  5. PPI
- 2. CYP51A1
  3. cytochrome P450 family …
  4. 0.956
  5. PPI
- 2. EMC7
  3. ER membrane protein com…
  4. 0.954
  5. Complex
- 2. PPM1A
  3. protein phosphatase, Mg…
  4. 0.953
  5. PPI
- 2. ALG3
  3. ALG3 alpha-1,3- mannosy…
  4. 0.951
  5. Metabolic
- 2. FANCD2
  3. FA complementation grou…
  4. 0.948
  5. PPI
- 2. DNAJA2
  3. DnaJ heat shock protein…
  4. 0.945
  5. PPI

Subnetwork gene interactions

ENSG00000087111

phosphatidylinositol glycan anchor biosynthesis class S

FunCoup

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Ensembl

ENSG00000087111

UniProt

NCBI

94005

PIGK

phosphatidylinositol glycan anchor biosynthesis class K

FunCoup

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Ensembl

ENSG00000142892

UniProt

NCBI

10026

CERS2

ceramide synthase 2

FunCoup

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Ensembl

ENSG00000143418

UniProt

NCBI

29956

RPN1

ribophorin I

FunCoup

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Ensembl

ENSG00000163902

UniProt

NCBI

6184

CERS6

ceramide synthase 6

FunCoup

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Ensembl

ENSG00000172292

UniProt

Q6ZMG9

NCBI

253782

SF3B1

splicing factor 3b subunit 1

FunCoup

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Ensembl

ENSG00000115524

UniProt

NCBI

23451

FANCD2

FA complementation group D2

FunCoup

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Ensembl

ENSG00000144554

UniProt

NCBI

2177

CYP51A1

cytochrome P450 family 51 subfamily A member 1

FunCoup

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Ensembl

ENSG00000001630

UniProt

NCBI

1595

EMC1

ER membrane protein complex subunit 1

FunCoup

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Ensembl

ENSG00000127463

UniProt

NCBI

23065

FBXO6

F-box protein 6

FunCoup

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Ensembl

ENSG00000116663

UniProt

NCBI

26270

EMC4

ER membrane protein complex subunit 4

FunCoup

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Ensembl

ENSG00000128463

UniProt

NCBI

51234

NDUFA9

NADH:ubiquinone oxidoreductase subunit A9

FunCoup

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Ensembl

ENSG00000139180

UniProt

NCBI

4704

DNAJC8

DnaJ heat shock protein family (Hsp40) member C8

FunCoup

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Ensembl

ENSG00000126698

UniProt

NCBI

22826

CERS5

ceramide synthase 5

FunCoup

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Ensembl

ENSG00000139624

UniProt

NCBI

91012

VCP

valosin containing protein

FunCoup

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Ensembl

ENSG00000165280

UniProt

NCBI

7415

DNAJA2

DnaJ heat shock protein family (Hsp40) member A2

FunCoup

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Ensembl

ENSG00000069345

UniProt

NCBI

10294

PIGT

phosphatidylinositol glycan anchor biosynthesis class T

FunCoup

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Ensembl

ENSG00000124155

UniProt

NCBI

51604

MPDU1

mannose-P-dolichol utilization defect 1

FunCoup

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Ensembl

ENSG00000129255

UniProt

NCBI

9526

TECR

trans-2,3-enoyl-CoA reductase

FunCoup

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Ensembl

ENSG00000099797

UniProt

NCBI

9524

PIGU

phosphatidylinositol glycan anchor biosynthesis class U

FunCoup

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Ensembl

ENSG00000101464

UniProt

NCBI

128869

GPAA1

glycosylphosphatidylinositol anchor attachment 1

FunCoup

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Ensembl

ENSG00000197858

UniProt

NCBI

8733

PPM1A

protein phosphatase, Mg2+/Mn2+ dependent 1A

FunCoup

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Ensembl

ENSG00000100614

UniProt

NCBI

5494

YIPF5

Yip1 domain family member 5

FunCoup

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Ensembl

ENSG00000145817

UniProt

NCBI

81555

TUSC3

tumor suppressor candidate 3

FunCoup

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Ensembl

ENSG00000104723

UniProt

NCBI

7991

EMC7

ER membrane protein complex subunit 7

FunCoup

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Ensembl

ENSG00000134153

UniProt

NCBI

56851

GPR89A

G protein-coupled receptor 89A

FunCoup

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Ensembl

ENSG00000117262

UniProt

NCBI

51463
653519

ALG3

ALG3 alpha-1,3- mannosyltransferase

FunCoup

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Ensembl

ENSG00000214160

UniProt

NCBI

10195

CERS4

ceramide synthase 4

FunCoup

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Ensembl

ENSG00000090661

UniProt

NCBI

79603

GPR89B

G protein-coupled receptor 89B

FunCoup

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Ensembl

ENSG00000188092

UniProt

NCBI

51463
653519

ERN1

endoplasmic reticulum to nucleus signaling 1

FunCoup

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Ensembl

ENSG00000178607

UniProt

O75460

NCBI

2081

ACAP2

ArfGAP with coiled-coil, ankyrin repeat and PH domains 2

FunCoup

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Ensembl

ENSG00000114331

UniProt

NCBI

23527

Query genes

		Identifier	Description
30	ENSG00000087111	ENSG00000087111	phosphatidylinositol glycan anchor biosynthesis class S
		UniProt	H0Y2N5 K7EN97 Q96S52
		NCBI	94005
		KEGG metabolic	Glycosylphosphatidylinositol (GPI)-anchor biosynthesis

Subnetwork genes

		Identifier	Description
29	PIGK	ENSG00000142892	phosphatidylinositol glycan anchor biosynthesis class K
		UniProt	A6NEM5 B1AK81 Q92643 S4R3M5
		NCBI	10026
		KEGG metabolic	Glycosylphosphatidylinositol (GPI)-anchor biosynthesis
12	CERS2	ENSG00000143418	ceramide synthase 2
		UniProt	H0YKH6 H0YLQ6 H0YNU7 Q5SZE1 Q5SZE2 Q5SZE3 Q5SZE4 Q96G23
		NCBI	29956
		KEGG signaling	Sphingolipid signaling pathway
		KEGG metabolic	Sphingolipid metabolism
25	RPN1	ENSG00000163902	ribophorin I
		UniProt	B7Z4L4 F8WF32 P04843
		NCBI	6184
		KEGG metabolic	N-Glycan biosynthesis Various types of N-glycan biosynthesis Protein processing in endoplasmic reticulum
10	CERS6	ENSG00000172292	ceramide synthase 6
		UniProt	Q6ZMG9
		NCBI	253782
		KEGG signaling	Sphingolipid signaling pathway
		KEGG metabolic	Sphingolipid metabolism
14	SF3B1	ENSG00000115524	splicing factor 3b subunit 1
		UniProt	A0A494C1M2 B4DGZ4 F8WC19 H7C341 O75533
		NCBI	23451
		KEGG metabolic	Spliceosome
11	FANCD2	ENSG00000144554	FA complementation group D2
		UniProt	F8WE37 H7BZJ7 Q9BXW9
		NCBI	2177
		KEGG metabolic	Fanconi anemia pathway
16	CYP51A1	ENSG00000001630	cytochrome P450 family 51 subfamily A member 1
		UniProt	A0A0C4DFL7 H7C0D0 Q16850
		NCBI	1595
		KEGG metabolic	Steroid biosynthesis
19	EMC1	ENSG00000127463	ER membrane protein complex subunit 1
		UniProt	A0A286YEW0 H7C4E3 H7C5A2 Q5TG59 Q8N766
		NCBI	23065
9	FBXO6	ENSG00000116663	F-box protein 6
		UniProt	J3KQ72 Q9NRD1
		NCBI	26270
		KEGG metabolic	Protein processing in endoplasmic reticulum
19	EMC4	ENSG00000128463	ER membrane protein complex subunit 4
		UniProt	H0YK61 H0YKL2 H0YLP8 H0YMH5 H0YN63 H0YNK0 H0YNK8 Q5J8M3 S4R329
		NCBI	51234
17	NDUFA9	ENSG00000139180	NADH:ubiquinone oxidoreductase subunit A9
		UniProt	F5GY40 F5H0J3 Q16795
		NCBI	4704
		KEGG signaling	Retrograde endocannabinoid signaling
		KEGG metabolic	Oxidative phosphorylation
16	DNAJC8	ENSG00000126698	DnaJ heat shock protein family (Hsp40) member C8
		UniProt	O75937 S4R3J5
		NCBI	22826
17	CERS5	ENSG00000139624	ceramide synthase 5
		UniProt	B4DQR7 F8VQZ6 F8VSK7 F8VXY1 F8VY42 F8W1K4 F8W1N7 F8W1Z3 H0YHG4 H0YHK2 H0YI10 H0YIG1 Q49AQ3 Q8N5B7
		NCBI	91012
		KEGG signaling	Sphingolipid signaling pathway
		KEGG metabolic	Sphingolipid metabolism
24	VCP	ENSG00000165280	valosin containing protein
		UniProt	C9IZA5 C9JUP7 P55072
		NCBI	7415
		KEGG metabolic	Protein processing in endoplasmic reticulum
16	DNAJA2	ENSG00000069345	DnaJ heat shock protein family (Hsp40) member A2
		UniProt	A0A087WT48 I3L320 O60884
		NCBI	10294
		KEGG metabolic	Protein processing in endoplasmic reticulum
24	PIGT	ENSG00000124155	phosphatidylinositol glycan anchor biosynthesis class T
		UniProt	A0A1W2PNP0 A0A1W2PNS2 A0A1W2PNW9 A0A1W2PNZ5 A0A1W2PP03 A0A1W2PP13 A0A1W2PP53 A0A1W2PP57 A0A1W2PP91 A0A1W2PP98 A0A1W2PPC3 A0A1W2PPI8 A0A1W2PPK4 A0A1W2PPQ7 A0A1W2PPR6 A0A1W2PPS0 A0A1W2PPU8 A0A1W2PQ29 A0A1W2PQ50 A0A1W2PQ52 A0A1W2PQA4 A0A1W2PQI9 A0A1W2PQL3 A0A1W2PQL9 A0A1W2PQN1 A0A1W2PQY1 A0A1W2PR22 A0A1W2PR34 A0A1W2PR70 A0A1W2PR73 A0A1W2PR92 A0A1W2PRB4 A0A1W2PRG1 A0A1W2PRH2 A0A1W2PRH8 A0A1W2PRL6 A0A1W2PRV7 A0A1W2PRZ8 A0A1W2PSC5 B7Z7C5 H7C2Y2 Q969N2
		NCBI	51604
		KEGG metabolic	Glycosylphosphatidylinositol (GPI)-anchor biosynthesis
24	MPDU1	ENSG00000129255	mannose-P-dolichol utilization defect 1
		UniProt	I3L1D2 I3L261 I3L295 I3L405 I3L4E0 I3L4T1 J3KSI4 J3KT75 J3KTK8 J3QQZ4 J3QRD5 J3QS48 J3QW43 O75352
		NCBI	9526
22	TECR	ENSG00000099797	trans-2,3-enoyl-CoA reductase
		UniProt	M0R2E5 M0R2N5 M0R329 M0R3C3 Q9NZ01
		NCBI	9524
		KEGG metabolic	Biosynthesis of unsaturated fatty acids Fatty acid elongation Fatty acid metabolism
20	PIGU	ENSG00000101464	phosphatidylinositol glycan anchor biosynthesis class U
		UniProt	Q5JWU1 Q9H490
		NCBI	128869
		KEGG metabolic	Glycosylphosphatidylinositol (GPI)-anchor biosynthesis
22	GPAA1	ENSG00000197858	glycosylphosphatidylinositol anchor attachment 1
		UniProt	E9PLG8 E9PLV6 E9PM11 E9PM94 E9PPZ9 E9PQ31 O43292
		NCBI	8733
		KEGG metabolic	Glycosylphosphatidylinositol (GPI)-anchor biosynthesis
12	PPM1A	ENSG00000100614	protein phosphatase, Mg2+/Mn2+ dependent 1A
		UniProt	E9PJN3 E9PKB5 E9PL75 E9PNE1 E9PP44 P35813
		NCBI	5494
		KEGG signaling	MAPK signaling pathway
24	YIPF5	ENSG00000145817	Yip1 domain family member 5
		UniProt	E5RGR9 E5RHH4 Q969M3
		NCBI	81555
17	TUSC3	ENSG00000104723	tumor suppressor candidate 3
		UniProt	A0A0A0MTC2 D6RA37 D6RDV0 D6RIY7 Q13454
		NCBI	7991
		KEGG metabolic	N-Glycan biosynthesis Various types of N-glycan biosynthesis Protein processing in endoplasmic reticulum
20	EMC7	ENSG00000134153	ER membrane protein complex subunit 7
		UniProt	H0YDT8 H0YDX2 Q9NPA0
		NCBI	56851
7	GPR89A	ENSG00000117262	G protein-coupled receptor 89A
		UniProt	B7ZAQ6 E9PKY3 E9PRZ5
		NCBI	51463 653519
17	ALG3	ENSG00000214160	ALG3 alpha-1,3- mannosyltransferase
		UniProt	C9J7S5 F8WE30 F8WF93 H7BZZ2 H7C0X4 Q92685
		NCBI	10195
		KEGG metabolic	N-Glycan biosynthesis Various types of N-glycan biosynthesis
8	CERS4	ENSG00000090661	ceramide synthase 4
		UniProt	H0YKC9 H0YKR4 H0YKS3 H0YLY3 H0YMY6 H0YN04 H0YNR6 Q9HA82
		NCBI	79603
		KEGG signaling	Sphingolipid signaling pathway
		KEGG metabolic	Sphingolipid metabolism
4	GPR89B	ENSG00000188092	G protein-coupled receptor 89B
		UniProt	A0A087WW78 A0A087WW82 P0CG08 U3KPV2
		NCBI	51463 653519
13	ERN1	ENSG00000178607	endoplasmic reticulum to nucleus signaling 1
		UniProt	O75460
		NCBI	2081
		KEGG signaling	Apoptosis
		KEGG metabolic	Protein processing in endoplasmic reticulum Autophagy - animal
4	ACAP2	ENSG00000114331	ArfGAP with coiled-coil, ankyrin repeat and PH domains 2
		UniProt	A0A087X1H5 A0A0U1RQT1 A0A5F9ZHJ9 C9J8L1 F8WAU0 H7C3K3 H7C3Q8 Q15057
		NCBI	23527
		KEGG metabolic	Endocytosis

Enrichment analysis

Search for enrichment of pathways or functional gene sets for your subnetwork genes

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	jSquid_subnetworks.xml	286.61 KB
	H.sapiens_subnetwork.tsv	47.62 KB

Species:

Network information:

Filter Results:

Network appearance:

ENSG00000087111

PIGK

CERS2

RPN1

CERS6

SF3B1

FANCD2

CYP51A1

EMC1

FBXO6

EMC4

NDUFA9

DNAJC8

CERS5

VCP

DNAJA2

PIGT

MPDU1

TECR

PIGU

GPAA1

PPM1A

YIPF5

TUSC3

EMC7

GPR89A

ALG3

CERS4

GPR89B

ERN1

ACAP2

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