Found 1 of 1 query genes

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Query interactions

Interaction partners
Confidence
Network
MEX
PIN
SCL
PHP
MIR
TFB
PEX
GIN
DOM
QMS
GRG
Evidence types
HSA
MMU
RNO
CFA
GGA
DRE
CIN
DME
CEL
BTA
SCE
ATH
SPO
BSU
ECO
PFA
DDI
SSO
SSC
MJA
OSA
Species
In Gold st.

ID Query gene
ID Query ortholog

Log-likelihood ratio (LLR)
	Highly positive
	Positive
	Zero
	Negative
	Highly negative
Known coupling
	This network
	Other network

2. ENSG00000085117
3. CD82 molecule
- 2. CD81
  3. CD81 molecule
  4. 0.998
  5. PPI
- 2. CD151
  3. CD151 molecule (Raph bl…
  4. 0.996
  5. PPI
- 2. CD9
  3. CD9 molecule
  4. 0.993
  5. PPI
- 2. GGT1 (1 of 2)
  3. novel protein
  4. 0.992
  5. PPI
- 2. GGT1 (2 of 2)
  3. gamma-glutamyltransfera…
  4. 0.981
  5. PPI
- 2. ACTB
  3. actin beta
  4. 0.980
  5. PPI
- 2. LGALS3BP
  3. galectin 3 binding prot…
  4. 0.974
  5. PPI
- 2. ITGAL
  3. integrin subunit alpha L
  4. 0.973
  5. PPI
- 2. IGSF8
  3. immunoglobulin superfam…
  4. 0.968
  5. PPI
- 2. CD46
  3. CD46 molecule
  4. 0.952
  5. PPI
- 2. HSP90AA1
  3. heat shock protein 90 a…
  4. 0.933
  5. PPI
- 2. ATP6V0D1
  3. ATPase H+ transporting …
  4. 0.929
  5. PPI
- 2. CD4
  3. CD4 molecule
  4. 0.913
  5. PPI
- 2. VANGL1
  3. VANGL planar cell polar…
  4. 0.902
  5. PPI
- 2. ERBB3
  3. erb-b2 receptor tyrosin…
  4. 0.884
  5. PPI
- 2. SET
  3. SET nuclear proto-oncog…
  4. 0.883
  5. PPI
- 2. HLA-DMB
  3. major histocompatibilit…
  4. 0.882
  5. PPI
- 2. HBEGF
  3. heparin binding EGF lik…
  4. 0.878
  5. PPI
- 2. SPR
  3. sepiapterin reductase
  4. 0.870
  5. Complex
- 2. TNFAIP3
  3. TNF alpha induced prote…
  4. 0.835
  5. Complex
- 2. EEF1A1
  3. eukaryotic translation …
  4. 0.793
  5. Metabolic
- 2. VIM
  3. vimentin
  4. 0.770
  5. PPI
- 2. TM9SF2
  3. transmembrane 9 superfa…
  4. 0.717
  5. Metabolic
- 2. PTBP1
  3. polypyrimidine tract bi…
  4. 0.621
  5. Metabolic
- 2. DBI
  3. diazepam binding inhibi…
  4. 0.589
  5. Metabolic
- 2. TNF
  3. tumor necrosis factor
  4. 0.582
  5. Complex
- 2. CREB3
  3. cAMP responsive element…
  4. 0.581
  5. PPI
- 2. GLOD4
  3. glyoxalase domain conta…
  4. 0.567
  5. Metabolic
- 2. PLSCR1
  3. phospholipid scramblase…
  4. 0.562
  5. Metabolic
- 2. GPI
  3. glucose-6-phosphate iso…
  4. 0.546
  5. Metabolic

Subnetwork gene interactions

ENSG00000085117

CD82 molecule

FunCoup

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Ensembl

ENSG00000085117

UniProt

NCBI

3732

CD9

CD9 molecule

FunCoup

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Ensembl

ENSG00000010278

UniProt

NCBI

CD151

CD151 molecule (Raph blood group)

FunCoup

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Ensembl

ENSG00000177697

UniProt

NCBI

LGALS3BP

galectin 3 binding protein

FunCoup

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Ensembl

ENSG00000108679

UniProt

NCBI

3959

GGT1 (1 of 2)

novel protein

FunCoup

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Ensembl

ENSG00000286070

UniProt

NCBI

2678

PTBP1

polypyrimidine tract binding protein 1

FunCoup

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Ensembl

ENSG00000011304

UniProt

NCBI

5725

DBI

diazepam binding inhibitor, acyl-CoA binding protein

FunCoup

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Ensembl

ENSG00000155368

UniProt

NCBI

1622

TNF

tumor necrosis factor

FunCoup

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Ensembl

ENSG00000232810

UniProt

P01375

NCBI

7124

SPR

sepiapterin reductase

FunCoup

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Ensembl

ENSG00000116096

UniProt

P35270

NCBI

6697

ATP6V0D1

ATPase H+ transporting V0 subunit d1

FunCoup

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Ensembl

ENSG00000159720

UniProt

NCBI

9114

CD81

CD81 molecule

FunCoup

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Ensembl

ENSG00000110651

UniProt

NCBI

CD46

CD46 molecule

FunCoup

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Ensembl

ENSG00000117335

UniProt

NCBI

4179

PLSCR1

phospholipid scramblase 1

FunCoup

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Ensembl

ENSG00000188313

UniProt

NCBI

5359

EEF1A1

eukaryotic translation elongation factor 1 alpha 1

FunCoup

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Ensembl

ENSG00000156508

UniProt

NCBI

1915

TM9SF2

transmembrane 9 superfamily member 2

FunCoup

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Ensembl

ENSG00000125304

UniProt

NCBI

9375

IGSF8

immunoglobulin superfamily member 8

FunCoup

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Ensembl

ENSG00000162729

UniProt

NCBI

93185

CD4

CD4 molecule

FunCoup

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Ensembl

ENSG00000010610

UniProt

NCBI

GLOD4

glyoxalase domain containing 4

FunCoup

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Ensembl

ENSG00000167699

UniProt

NCBI

51031

ITGAL

integrin subunit alpha L

FunCoup

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Ensembl

ENSG00000005844

UniProt

NCBI

3683

HSP90AA1

heat shock protein 90 alpha family class A member 1

FunCoup

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Ensembl

ENSG00000080824

UniProt

NCBI

3320

SET

SET nuclear proto-oncogene

FunCoup

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Ensembl

ENSG00000119335

UniProt

NCBI

6418

CREB3

cAMP responsive element binding protein 3

FunCoup

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Ensembl

ENSG00000107175

UniProt

O43889

NCBI

10488

TNFAIP3

TNF alpha induced protein 3

FunCoup

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Ensembl

ENSG00000118503

UniProt

NCBI

7128

ACTB

actin beta

FunCoup

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Ensembl

ENSG00000075624

UniProt

NCBI

GGT1 (2 of 2)

gamma-glutamyltransferase 1

FunCoup

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Ensembl

ENSG00000100031

UniProt

NCBI

2678

GPI

glucose-6-phosphate isomerase

FunCoup

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Ensembl

ENSG00000105220

UniProt

NCBI

2821

VANGL1

VANGL planar cell polarity protein 1

FunCoup

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Ensembl

ENSG00000173218

UniProt

Q8TAA9

NCBI

81839

ERBB3

erb-b2 receptor tyrosine kinase 3

FunCoup

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Ensembl

ENSG00000065361

UniProt

NCBI

2065

VIM

vimentin

FunCoup

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Ensembl

ENSG00000026025

UniProt

NCBI

7431

HLA-DMB

major histocompatibility complex, class II, DM beta

FunCoup

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Ensembl

ENSG00000242574

UniProt

NCBI

3109

HBEGF

heparin binding EGF like growth factor

FunCoup

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Ensembl

ENSG00000113070

UniProt

Q99075

NCBI

1839

Query genes

		Identifier	Description
30	ENSG00000085117	ENSG00000085117	CD82 molecule
		UniProt	E9PJ45 E9PJ59 E9PJB7 E9PJC7 E9PJK9 E9PM43 E9PP61 H0YD57 P27701
		NCBI	3732
		KEGG signaling	p53 signaling pathway

Subnetwork genes

		Identifier	Description
13	CD9	ENSG00000010278	CD9 molecule
		UniProt	A0A087WU13 A0A2R8Y478 A6NNI4 F5GXT1 G8JLH6 P21926
		NCBI	928
		KEGG signaling	Hematopoietic cell lineage
5	CD151	ENSG00000177697	CD151 molecule (Raph blood group)
		UniProt	E9PJC8 E9PJE8 E9PK37 E9PLZ6 E9PMR4 E9PP93 E9PRJ3 E9PSA1 K4DIA7 K4DIB7 P48509
		NCBI	977
7	LGALS3BP	ENSG00000108679	galectin 3 binding protein
		UniProt	K7EJD3 K7EJY8 K7EKQ5 K7ELA1 K7EM15 K7EN99 K7EP36 K7EQT9 K7ER67 K7ERZ6 K7ES75 K7ESM3 Q08380
		NCBI	3959
3	GGT1 (1 of 2)	ENSG00000286070	novel protein
		UniProt	H3BT13 P19440
		NCBI	2678
		KEGG metabolic	Arachidonic acid metabolism Glutathione metabolism Taurine and hypotaurine metabolism
11	PTBP1	ENSG00000011304	polypyrimidine tract binding protein 1
		UniProt	A0A087WTS6 A0A087WU68 A0A087WUW5 A0A0D9SF20 A0A0U1RRM4 A6NLN1 K7EK45 K7EKJ7 K7EKX4 K7ELW5 K7ES59 P26599
		NCBI	5725
13	DBI	ENSG00000155368	diazepam binding inhibitor, acyl-CoA binding protein
		UniProt	A0A0A0MTI5 B8ZWD1 P07108
		NCBI	1622
		KEGG signaling	PPAR signaling pathway
5	TNF	ENSG00000232810	tumor necrosis factor
		UniProt	P01375
		NCBI	7124
		KEGG signaling	MAPK signaling pathway TGF-beta signaling pathway NF-kappa B signaling pathway mTOR signaling pathway Viral protein interaction with cytokine and cytokine receptor Cytokine-cytokine receptor interaction Sphingolipid signaling pathway Adipocytokine signaling pathway Antigen processing and presentation RIG-I-like receptor signaling pathway NOD-like receptor signaling pathway Fc epsilon RI signaling pathway Toll-like receptor signaling pathway Hematopoietic cell lineage Apoptosis Natural killer cell mediated cytotoxicity T cell receptor signaling pathway C-type lectin receptor signaling pathway TNF signaling pathway IL-17 signaling pathway
10	SPR	ENSG00000116096	sepiapterin reductase
		UniProt	P35270
		NCBI	6697
		KEGG metabolic	Folate biosynthesis
12	ATP6V0D1	ENSG00000159720	ATPase H+ transporting V0 subunit d1
		UniProt	F5GYQ1 F8WEN9 H3BPS0 H3BQB4 H3BQJ1 H3BSG7 H3BTB4 H3BTB5 H3BUQ0 J3QL14 P61421 R4GN72
		NCBI	9114
		KEGG signaling	Synaptic vesicle cycle
		KEGG metabolic	Oxidative phosphorylation Phagosome Lysosome
16	CD81	ENSG00000110651	CD81 molecule
		UniProt	A6NMH8 E9PIF1 E9PJK1 E9PM31 E9PPF5 E9PQV4 E9PRJ8 H0YDJ9 H0YDL9 H0YEE2 P60033
		NCBI	975
		KEGG signaling	B cell receptor signaling pathway
6	CD46	ENSG00000117335	CD46 molecule
		UniProt	P15529 R4GN18
		NCBI	4179
		KEGG signaling	Complement and coagulation cascades
9	PLSCR1	ENSG00000188313	phospholipid scramblase 1
		UniProt	C9J0H3 C9J7K9 C9J9P4 C9JE06 F2Z3F2 H7C5I5 O15162
		NCBI	5359
15	EEF1A1	ENSG00000156508	eukaryotic translation elongation factor 1 alpha 1
		UniProt	A0A087WV01 A0A087WVQ9 A6PW80 P68104 Q5JR01
		NCBI	1915
		KEGG metabolic	RNA transport
14	TM9SF2	ENSG00000125304	transmembrane 9 superfamily member 2
		UniProt	A0A2R8Y4S7 Q99805
		NCBI	9375
2	IGSF8	ENSG00000162729	immunoglobulin superfamily member 8
		UniProt	C9J8Z4 Q969P0
		NCBI	93185
6	CD4	ENSG00000010610	CD4 molecule
		UniProt	F5GYA9 F5H480 P01730
		NCBI	920
		KEGG signaling	Antigen processing and presentation Hematopoietic cell lineage T cell receptor signaling pathway Cytokine-cytokine receptor interaction Cell adhesion molecules (CAMs)
3	GLOD4	ENSG00000167699	glyoxalase domain containing 4
		UniProt	F6TLX2 I3L1F4 I3L1I0 I3L277 I3L2C2 I3L3G0 I3L3Q4 I3NI24 I3NI27 K7ENF2 Q9HC38
		NCBI	51031
2	ITGAL	ENSG00000005844	integrin subunit alpha L
		UniProt	B4DQ77 B4E021 H3BNL5 H3BS37 H3BSV1 H3BUT3 I3L1D1 I3L468 P20701
		NCBI	3683
		KEGG signaling	Rap1 signaling pathway Natural killer cell mediated cytotoxicity Leukocyte transendothelial migration Cell adhesion molecules (CAMs)
12	HSP90AA1	ENSG00000080824	heat shock protein 90 alpha family class A member 1
		UniProt	A0A0U1RR69 G3V2J8 G3V592 H0YJF5 P07900
		NCBI	3320
		KEGG signaling	Antigen processing and presentation NOD-like receptor signaling pathway PI3K-Akt signaling pathway Estrogen signaling pathway Progesterone-mediated oocyte maturation IL-17 signaling pathway
		KEGG metabolic	Protein processing in endoplasmic reticulum
9	SET	ENSG00000119335	SET nuclear proto-oncogene
		UniProt	A0A0C4DFV9 B2REB7 Q01105
		NCBI	6418
2	CREB3	ENSG00000107175	cAMP responsive element binding protein 3
		UniProt	O43889
		NCBI	10488
		KEGG signaling	cAMP signaling pathway cGMP-PKG signaling pathway Melanogenesis AMPK signaling pathway Relaxin signaling pathway Estrogen signaling pathway Dopaminergic synapse Adrenergic signaling in cardiomyocytes PI3K-Akt signaling pathway Cholinergic synapse Glucagon signaling pathway TNF signaling pathway
5	TNFAIP3	ENSG00000118503	TNF alpha induced protein 3
		UniProt	A0A087WU80 A0A087WVN3 A0A087WXL5 A0A087X1N1 D3TTY5 P21580 Q5VXQ8 Q5VXQ9 Q5VXR0
		NCBI	7128
		KEGG signaling	NOD-like receptor signaling pathway NF-kappa B signaling pathway TNF signaling pathway IL-17 signaling pathway
16	ACTB	ENSG00000075624	actin beta
		UniProt	A0A2R8Y793 A0A2R8YEA7 A0A2R8YFE2 A0A2R8YGF8 C9JTX5 C9JUM1 C9JZR7 E7EVS6 G5E9R0 P60709
		NCBI	60
		KEGG signaling	Focal adhesion Rap1 signaling pathway Adherens junction Tight junction Apoptosis Thyroid hormone signaling pathway Leukocyte transendothelial migration Hippo signaling pathway Oxytocin signaling pathway
		KEGG metabolic	Phagosome
3	GGT1 (2 of 2)	ENSG00000100031	gamma-glutamyltransferase 1
		UniProt	B5MC34 B5MC36 C9JGF3 C9JIY6 E7EM62 E7ENJ5 E7ERN9 E7ESL5 E7ET76 E7ETJ6 E7ETN1 E7ETR7 E7ETU4 E7EVF8 E9PHP2 P19440
		NCBI	2678
		KEGG metabolic	Arachidonic acid metabolism Glutathione metabolism Taurine and hypotaurine metabolism
15	GPI	ENSG00000105220	glucose-6-phosphate isomerase
		UniProt	A0A0G2JLI6 A0A2R8Y6C7 A0A2R8YF08 A0A2U3TZU2 K7EIL4 K7ELR7 K7ENA0 K7EP41 K7EPY4 K7EQ48 K7ERC6 K7ERK8 P06744
		NCBI	2821
		KEGG metabolic	Starch and sucrose metabolism Pentose phosphate pathway Glycolysis / Gluconeogenesis Carbon metabolism Amino sugar and nucleotide sugar metabolism
2	VANGL1	ENSG00000173218	VANGL planar cell polarity protein 1
		UniProt	Q8TAA9
		NCBI	81839
		KEGG signaling	Wnt signaling pathway
1	ERBB3	ENSG00000065361	erb-b2 receptor tyrosine kinase 3
		UniProt	A0A2R8Y6T4 B3KWG5 B4DGQ7 F8VRI5 F8VRL0 F8VW48 F8VW56 F8VX90 F8VYK4 O75812 P21860
		NCBI	2065
		KEGG signaling	ErbB signaling pathway MAPK signaling pathway Calcium signaling pathway PI3K-Akt signaling pathway
13	VIM	ENSG00000026025	vimentin
		UniProt	A0A1B0GTT5 A0A1B0GVG8 B0YJC4 B0YJC5 P08670
		NCBI	7431
1	HLA-DMB	ENSG00000242574	major histocompatibility complex, class II, DM beta
		UniProt	H0Y4B8 H0Y7A2 P28068
		NCBI	3109
		KEGG signaling	Antigen processing and presentation Hematopoietic cell lineage Intestinal immune network for IgA production Cell adhesion molecules (CAMs)
		KEGG metabolic	Phagosome
1	HBEGF	ENSG00000113070	heparin binding EGF like growth factor
		UniProt	Q99075
		NCBI	1839
		KEGG signaling	ErbB signaling pathway Estrogen signaling pathway GnRH signaling pathway

Enrichment analysis

Search for enrichment of pathways or functional gene sets for your subnetwork genes

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	jSquid_subnetworks.xml	259.07 KB
	H.sapiens_subnetwork.tsv	22.63 KB

Species:

Network information:

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Network appearance:

ENSG00000085117

CD9

CD151

LGALS3BP

GGT1 (1 of 2)

PTBP1

DBI

TNF

SPR

ATP6V0D1

CD81

CD46

PLSCR1

EEF1A1

TM9SF2

IGSF8

CD4

GLOD4

ITGAL

HSP90AA1

SET

CREB3

TNFAIP3

ACTB

GGT1 (2 of 2)

GPI

VANGL1

ERBB3

VIM

HLA-DMB

HBEGF

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