Found 1 of 1 query genes

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Query interactions

Interaction partners
Confidence
Network
MEX
PIN
SCL
PHP
MIR
TFB
PEX
GIN
DOM
QMS
GRG
Evidence types
HSA
MMU
RNO
CFA
GGA
DRE
CIN
DME
CEL
BTA
SCE
ATH
SPO
BSU
ECO
PFA
DDI
SSO
SSC
MJA
OSA
Species
In Gold st.

ID Query gene
ID Query ortholog

Log-likelihood ratio (LLR)
	Highly positive
	Positive
	Zero
	Negative
	Highly negative
Known coupling
	This network
	Other network

2. ENSG00000076826
3. calmodulin regulated sp…
- 2. MCM3
  3. minichromosome maintena…
  4. 1.000
  5. PPI
- 2. KCNAB2
  3. potassium voltage-gated…
  4. 0.971
  5. Complex
- 2. TUBB4A
  3. tubulin beta 4A class I…
  4. 0.952
  5. PPI
- 2. MCM5
  3. minichromosome maintena…
  4. 0.951
  5. PPI
- 2. PFKP
  3. phosphofructokinase, pl…
  4. 0.942
  5. Complex
- 2. SCRIB
  3. scribble planar cell po…
  4. 0.941
  5. Complex
- 2. PPP1CA
  3. protein phosphatase 1 c…
  4. 0.905
  5. PPI
- 2. PSRC1
  3. proline and serine rich…
  4. 0.890
  5. PPI
- 2. SLC9A1
  3. solute carrier family 9…
  4. 0.849
  5. Complex
- 2. CSNK1D
  3. casein kinase 1 delta
  4. 0.832
  5. Metabolic
- 2. AURKA
  3. aurora kinase A
  4. 0.831
  5. Metabolic
- 2. CCT5
  3. chaperonin containing T…
  4. 0.830
  5. Metabolic
- 2. DYNC1LI2
  3. dynein cytoplasmic 1 li…
  4. 0.828
  5. Metabolic
- 2. HOOK1
  3. hook microtubule tether…
  4. 0.818
  5. Metabolic
- 2. ATXN2L
  3. ataxin 2 like
  4. 0.812
  5. Complex
- 2. PAK1
  3. p21 (RAC1) activated ki…
  4. 0.775
  5. Metabolic
- 2. PLEKHA7
  3. pleckstrin homology dom…
  4. 0.769
  5. PPI
- 2. DBF4
  3. DBF4 zinc finger
  4. 0.768
  5. PPI
- 2. RAB11A
  3. RAB11A, member RAS onco…
  4. 0.743
  5. Metabolic
- 2. VPS18
  3. VPS18 core subunit of C…
  4. 0.733
  5. Complex
- 2. PKN2
  3. protein kinase N2
  4. 0.727
  5. Metabolic
- 2. CNOT6
  3. CCR4-NOT transcription …
  4. 0.678
  5. Complex
- 2. TUBGCP2
  3. tubulin gamma complex a…
  4. 0.652
  5. Metabolic
- 2. PDXP
  3. pyridoxal phosphatase
  4. 0.627
  5. Metabolic
- 2. SRI
  3. sorcin
  4. 0.624
  5. Complex
- 2. RAD51
  3. RAD51 recombinase
  4. 0.617
  5. Complex
- 2. MAPK14
  3. mitogen-activated prote…
  4. 0.605
  5. Metabolic
- 2. TGFBRAP1
  3. transforming growth fac…
  4. 0.589
  5. Complex
- 2. DCAF7
  3. DDB1 and CUL4 associate…
  4. 0.583
  5. PPI
- 2. CALM3
  3. calmodulin 3
  4. 0.555
  5. Metabolic

Subnetwork gene interactions

ENSG00000076826

calmodulin regulated spectrin associated protein family member 3

FunCoup

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Ensembl

ENSG00000076826

UniProt

Q9P1Y5

NCBI

57662

DYNC1LI2

dynein cytoplasmic 1 light intermediate chain 2

FunCoup

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Ensembl

ENSG00000135720

UniProt

NCBI

1783

HOOK1

hook microtubule tethering protein 1

FunCoup

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Ensembl

ENSG00000134709

UniProt

NCBI

51361

AURKA

aurora kinase A

FunCoup

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Ensembl

ENSG00000087586

UniProt

NCBI

6790

TUBGCP2

tubulin gamma complex associated protein 2

FunCoup

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Ensembl

ENSG00000130640

UniProt

NCBI

10844

ATXN2L

ataxin 2 like

FunCoup

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Ensembl

ENSG00000168488

UniProt

NCBI

11273

CALM3

calmodulin 3

FunCoup

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Ensembl

ENSG00000160014

UniProt

NCBI

MCM3

minichromosome maintenance complex component 3

FunCoup

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Ensembl

ENSG00000112118

UniProt

NCBI

4172

CCT5

chaperonin containing TCP1 subunit 5

FunCoup

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Ensembl

ENSG00000150753

UniProt

NCBI

22948

PFKP

phosphofructokinase, platelet

FunCoup

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Ensembl

ENSG00000067057

UniProt

NCBI

5214

PPP1CA

protein phosphatase 1 catalytic subunit alpha

FunCoup

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Ensembl

ENSG00000172531

UniProt

NCBI

5499

SRI

sorcin

FunCoup

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Ensembl

ENSG00000075142

UniProt

NCBI

6717

CNOT6

CCR4-NOT transcription complex subunit 6

FunCoup

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Ensembl

ENSG00000113300

UniProt

NCBI

VPS18

VPS18 core subunit of CORVET and HOPS complexes

FunCoup

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Ensembl

ENSG00000104142

UniProt

NCBI

57617

TUBB4A

tubulin beta 4A class IVa

FunCoup

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Ensembl

ENSG00000104833

UniProt

NCBI

10382

CSNK1D

casein kinase 1 delta

FunCoup

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Ensembl

ENSG00000141551

UniProt

NCBI

1453

MCM5

minichromosome maintenance complex component 5

FunCoup

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Ensembl

ENSG00000100297

UniProt

NCBI

4174

RAD51

RAD51 recombinase

FunCoup

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Ensembl

ENSG00000051180

UniProt

NCBI

5888

RAB11A

RAB11A, member RAS oncogene family

FunCoup

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Ensembl

ENSG00000103769

UniProt

NCBI

8766

MAPK14

mitogen-activated protein kinase 14

FunCoup

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Ensembl

ENSG00000112062

UniProt

NCBI

1432

PAK1

p21 (RAC1) activated kinase 1

FunCoup

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Ensembl

ENSG00000149269

UniProt

NCBI

5058

KCNAB2

potassium voltage-gated channel subfamily A regulatory beta subunit 2

FunCoup

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Ensembl

ENSG00000069424

UniProt

NCBI

8514

SLC9A1

solute carrier family 9 member A1

FunCoup

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Ensembl

ENSG00000090020

UniProt

NCBI

6548

PSRC1

proline and serine rich coiled-coil 1

FunCoup

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Ensembl

ENSG00000134222

UniProt

NCBI

84722

PKN2

protein kinase N2

FunCoup

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Ensembl

ENSG00000065243

UniProt

NCBI

5586

DBF4

DBF4 zinc finger

FunCoup

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Ensembl

ENSG00000006634

UniProt

NCBI

10926

DCAF7

DDB1 and CUL4 associated factor 7

FunCoup

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Ensembl

ENSG00000136485

UniProt

NCBI

10238

SCRIB

scribble planar cell polarity protein

FunCoup

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Ensembl

ENSG00000180900

UniProt

NCBI

23513

PDXP

pyridoxal phosphatase

FunCoup

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Ensembl

ENSG00000241360

UniProt

NCBI

57026

TGFBRAP1

transforming growth factor beta receptor associated protein 1

FunCoup

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Ensembl

ENSG00000135966

UniProt

Q8WUH2

NCBI

9392

PLEKHA7

pleckstrin homology domain containing A7

FunCoup

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Ensembl

ENSG00000166689

UniProt

NCBI

144100

Query genes

		Identifier	Description
30	ENSG00000076826	ENSG00000076826	calmodulin regulated spectrin associated protein family member 3
		UniProt	Q9P1Y5
		NCBI	57662

Subnetwork genes

		Identifier	Description
15	DYNC1LI2	ENSG00000135720	dynein cytoplasmic 1 light intermediate chain 2
		UniProt	B4E2E0 H3BU48 H3BUM4 J3KRI4 J3KRZ2 J3KSD2 J3QKK5 O43237
		NCBI	1783
		KEGG metabolic	Phagosome
8	HOOK1	ENSG00000134709	hook microtubule tethering protein 1
		UniProt	B1AK95 Q9UJC3
		NCBI	51361
15	AURKA	ENSG00000087586	aurora kinase A
		UniProt	A3KFJ0 A3KFJ1 A3KFJ2 O14965 Q5QPD1 Q5QPD2 Q5QPD4
		NCBI	6790
		KEGG signaling	Oocyte meiosis Progesterone-mediated oocyte maturation
14	TUBGCP2	ENSG00000130640	tubulin gamma complex associated protein 2
		UniProt	B3KTU7 F2Z2B9 Q9BSJ2 R4GMM4
		NCBI	10844
4	ATXN2L	ENSG00000168488	ataxin 2 like
		UniProt	A0A0C4DGL7 H3BMX1 H3BPQ7 H3BQ14 H3BQX7 H3BRB0 H3BSK9 H3BSQ5 H3BUE3 H3BUF6 Q8WWM7
		NCBI	11273
15	CALM3	ENSG00000160014	calmodulin 3
		UniProt	A0A590UJD7 M0QZ52 P0DP25 Q96HY3
		NCBI	801 805 808
		KEGG signaling	Calcium signaling pathway Apelin signaling pathway Adrenergic signaling in cardiomyocytes Vascular smooth muscle contraction Phosphatidylinositol signaling system Neurotrophin signaling pathway Phototransduction Long-term potentiation Oocyte meiosis Rap1 signaling pathway Ras signaling pathway Olfactory transduction cAMP signaling pathway cGMP-PKG signaling pathway Melanogenesis Estrogen signaling pathway Dopaminergic synapse GnRH signaling pathway Glucagon signaling pathway C-type lectin receptor signaling pathway Oxytocin signaling pathway Insulin signaling pathway
13	MCM3	ENSG00000112118	minichromosome maintenance complex component 3
		UniProt	A0A499FHX9 J3KQ69 P25205 Q7Z6P5
		NCBI	4172
		KEGG signaling	Cell cycle
		KEGG metabolic	DNA replication
20	CCT5	ENSG00000150753	chaperonin containing TCP1 subunit 5
		UniProt	B7ZAR1 D6RIZ7 E7ENZ3 E9PCA1 H0Y914 H0Y958 P48643
		NCBI	22948
6	PFKP	ENSG00000067057	phosphofructokinase, platelet
		UniProt	B1APP6 H0Y3Y3 H0Y757 Q01813 Q5VSR5 V9GY25 V9GYV7
		NCBI	5214
		KEGG signaling	Thyroid hormone signaling pathway HIF-1 signaling pathway AMPK signaling pathway Glucagon signaling pathway
		KEGG metabolic	RNA degradation Pentose phosphate pathway Galactose metabolism Fructose and mannose metabolism Glycolysis / Gluconeogenesis Biosynthesis of amino acids Carbon metabolism
19	PPP1CA	ENSG00000172531	protein phosphatase 1 catalytic subunit alpha
		UniProt	E9PMD7 F5H037 F5H1L6 P62136
		NCBI	5499
		KEGG signaling	Long-term potentiation Focal adhesion Oocyte meiosis cAMP signaling pathway cGMP-PKG signaling pathway Adrenergic signaling in cardiomyocytes Dopaminergic synapse Vascular smooth muscle contraction Hippo signaling pathway Insulin signaling pathway Oxytocin signaling pathway
		KEGG metabolic	mRNA surveillance pathway
5	SRI	ENSG00000075142	sorcin
		UniProt	B4DHQ6 C9J0K6 E9PG82 P30626
		NCBI	6717
5	CNOT6	ENSG00000113300	CCR4-NOT transcription complex subunit 6
		UniProt	D6R9H6 Q9ULM6
11	VPS18	ENSG00000104142	VPS18 core subunit of CORVET and HOPS complexes
		UniProt	H0YLM6 H0YMC9 Q9P253
		NCBI	57617
11	TUBB4A	ENSG00000104833	tubulin beta 4A class IVa
		UniProt	M0QX14 M0QY37 M0QY85 M0QYM7 M0QZL7 M0R042 M0R0M1 M0R0X0 M0R1I1 M0R278 M0R2D3 M0R2T4 P04350
		NCBI	10382
		KEGG signaling	Gap junction
		KEGG metabolic	Phagosome
17	CSNK1D	ENSG00000141551	casein kinase 1 delta
		UniProt	B4DLF1 H0Y2N6 H7BYT1 J3KRM8 J3KRS6 J3QQI9 J3QQU8 J3QS70 P48730
		NCBI	1453
		KEGG signaling	Gap junction Hedgehog signaling pathway Hippo signaling pathway
14	MCM5	ENSG00000100297	minichromosome maintenance complex component 5
		UniProt	B1AHA9 B1AHB1 B1AHB2 F8WFD7 P33992
		NCBI	4174
		KEGG signaling	Cell cycle
		KEGG metabolic	DNA replication
11	RAD51	ENSG00000051180	RAD51 recombinase
		UniProt	E9PI54 E9PJ30 E9PNT5 H0YD61 Q06609 Q9NZG9
		NCBI	5888
		KEGG metabolic	Fanconi anemia pathway Homologous recombination
18	RAB11A	ENSG00000103769	RAB11A, member RAS oncogene family
		UniProt	B4DQU5 H3BMH2 H3BN38 H3BSC1 P62491
		NCBI	8766
		KEGG metabolic	Endocytosis
12	MAPK14	ENSG00000112062	mitogen-activated protein kinase 14
		UniProt	B4E0K5 B5TY33 E7EX54 H7C4E2 Q16539
		NCBI	1432
		KEGG signaling	MAPK signaling pathway Leukocyte transendothelial migration Adrenergic signaling in cardiomyocytes VEGF signaling pathway Sphingolipid signaling pathway Neurotrophin signaling pathway RIG-I-like receptor signaling pathway NOD-like receptor signaling pathway Fc epsilon RI signaling pathway Oocyte meiosis Rap1 signaling pathway Toll-like receptor signaling pathway FoxO signaling pathway T cell receptor signaling pathway Prolactin signaling pathway Dopaminergic synapse Relaxin signaling pathway Progesterone-mediated oocyte maturation GnRH signaling pathway C-type lectin receptor signaling pathway TNF signaling pathway IL-17 signaling pathway Retrograde endocannabinoid signaling
8	PAK1	ENSG00000149269	p21 (RAC1) activated kinase 1
		UniProt	B3KNX7 E9PJF8 E9PKH9 E9PM17 E9PMP2 E9PQW5 E9PRP6 H0YCG5 H0YCM0 H0YF55 Q13153
		NCBI	5058
		KEGG signaling	Fc gamma R-mediated phagocytosis Focal adhesion Ras signaling pathway cAMP signaling pathway Natural killer cell mediated cytotoxicity ErbB signaling pathway T cell receptor signaling pathway MAPK signaling pathway Hippo signaling pathway - multiple species Chemokine signaling pathway C-type lectin receptor signaling pathway
5	KCNAB2	ENSG00000069424	potassium voltage-gated channel subfamily A regulatory beta subunit 2
		UniProt	A0A590UJ15 A0A590UJ35 A0A590UJ72 A0A590UJ79 A0A590UJB6 A0A590UJB8 A0A590UJI8 A0A590UJJ4 A0A590UJK5 A0A590UJU1 A0A590UJU4 A0A590UJV4 A0A590UJX9 A0A590UJY1 A0A590UK89 A0A5F9UN28 K7EIR5 K7EKU4 Q13303 Q5TG78 Q5TG81 Q5TG84
		NCBI	8514
4	SLC9A1	ENSG00000090020	solute carrier family 9 member A1
		UniProt	B1ALD5 P19634
		NCBI	6548
		KEGG signaling	cAMP signaling pathway Thyroid hormone signaling pathway Apelin signaling pathway Adrenergic signaling in cardiomyocytes Cardiac muscle contraction
3	PSRC1	ENSG00000134222	proline and serine rich coiled-coil 1
		UniProt	Q5T2Z0 Q5T2Z1 Q6PGN9 S4R3S8
		NCBI	84722
8	PKN2	ENSG00000065243	protein kinase N2
		UniProt	B1AL79 H0Y429 H0Y5V5 Q16513
		NCBI	5586
		KEGG signaling	NOD-like receptor signaling pathway PI3K-Akt signaling pathway
2	DBF4	ENSG00000006634	DBF4 zinc finger
		UniProt	B4DXK0 F8WF77 Q9UBU7
		NCBI	10926
		KEGG signaling	Cell cycle
6	DCAF7	ENSG00000136485	DDB1 and CUL4 associated factor 7
		UniProt	A0A087WWI6 P61962
		NCBI	10238
6	SCRIB	ENSG00000180900	scribble planar cell polarity protein
		UniProt	H0YCG0 H0YDF9 Q14160
		NCBI	23513
		KEGG signaling	Tight junction Hippo signaling pathway
1	PDXP	ENSG00000241360	pyridoxal phosphatase
		UniProt	B1AHD3 Q96GD0
		NCBI	57026
		KEGG metabolic	Vitamin B6 metabolism
3	TGFBRAP1	ENSG00000135966	transforming growth factor beta receptor associated protein 1
		UniProt	Q8WUH2
		NCBI	9392
1	PLEKHA7	ENSG00000166689	pleckstrin homology domain containing A7
		UniProt	A0A1B0GTN9 A0A1B0GUM1 A0A1B0GUN0 E9PIK1 E9PKC0 E9PL74 E9PN45 H0YDE2 Q6IQ23
		NCBI	144100

Enrichment analysis

Search for enrichment of pathways or functional gene sets for your subnetwork genes

To use PathwAX, first use the button below to copy the subnetwork genes and then paste them in PathwAX

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	jSquid_subnetworks.xml	272.15 KB
	H.sapiens_subnetwork.tsv	28.49 KB

Species:

Network information:

Filter Results:

Network appearance:

ENSG00000076826

DYNC1LI2

HOOK1

AURKA

TUBGCP2

ATXN2L

CALM3

MCM3

CCT5

PFKP

PPP1CA

SRI

CNOT6

VPS18

TUBB4A

CSNK1D

MCM5

RAD51

RAB11A

MAPK14

PAK1

KCNAB2

SLC9A1

PSRC1

PKN2

DBF4

DCAF7

SCRIB

PDXP

TGFBRAP1

PLEKHA7

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