Found 1 of 1 query genes

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Query interactions

Interaction partners
Confidence
Network
MEX
PIN
SCL
PHP
MIR
TFB
PEX
GIN
DOM
QMS
GRG
Evidence types
HSA
MMU
RNO
CFA
GGA
DRE
CIN
DME
CEL
BTA
SCE
ATH
SPO
BSU
ECO
PFA
DDI
SSO
SSC
MJA
OSA
Species
In Gold st.

ID Query gene
ID Query ortholog

Log-likelihood ratio (LLR)
	Highly positive
	Positive
	Zero
	Negative
	Highly negative
Known coupling
	This network
	Other network

2. ENSG00000057935
3. metastasis associated 1…
- 2. RBBP4
  3. RB binding protein 4, c…
  4. 1.000
  5. PPI
- 2. GATAD2A
  3. GATA zinc finger domain…
  4. 1.000
  5. PPI
- 2. RBBP7
  3. RB binding protein 7, c…
  4. 1.000
  5. PPI
- 2. HDAC1
  3. histone deacetylase 1
  4. 1.000
  5. PPI
- 2. GATAD2B
  3. GATA zinc finger domain…
  4. 1.000
  5. PPI
- 2. CHD4
  3. chromodomain helicase D…
  4. 1.000
  5. PPI
- 2. MBD3
  3. methyl-CpG binding doma…
  4. 1.000
  5. PPI
- 2. HDAC2
  3. histone deacetylase 2
  4. 1.000
  5. PPI
- 2. MTA2
  3. metastasis associated 1…
  4. 1.000
  5. PPI
- 2. MBD2
  3. methyl-CpG binding doma…
  4. 1.000
  5. PPI
- 2. KDM1A
  3. lysine demethylase 1A
  4. 1.000
  5. PPI
- 2. CHD5
  3. chromodomain helicase D…
  4. 1.000
  5. PPI
- 2. CHD3
  3. chromodomain helicase D…
  4. 1.000
  5. PPI
- 2. SIN3A
  3. SIN3 transcription regu…
  4. 1.000
  5. Complex
- 2. FOXK2
  3. forkhead box K2
  4. 1.000
  5. PPI
- 2. MTA1
  3. metastasis associated 1
  4. 1.000
  5. PPI
- 2. TFAP4
  3. transcription factor AP…
  4. 1.000
  5. PPI
- 2. ARNT
  3. aryl hydrocarbon recept…
  4. 0.999
  5. PPI
- 2. RAD21
  3. RAD21 cohesin complex c…
  4. 0.999
  5. PPI
- 2. PARP1
  3. poly(ADP-ribose) polyme…
  4. 0.998
  5. PPI
- 2. SMARCAD1
  3. SWI/SNF-related, matrix…
  4. 0.998
  5. PPI
- 2. SOX2
  3. SRY-box transcription f…
  4. 0.997
  5. PPI
- 2. SMARCC2
  3. SWI/SNF related, matrix…
  4. 0.997
  5. PPI
- 2. RCOR3
  3. REST corepressor 3
  4. 0.997
  5. PPI
- 2. SMARCC1
  3. SWI/SNF related, matrix…
  4. 0.997
  5. PPI
- 2. ACTL6A
  3. actin like 6A
  4. 0.996
  5. PPI
- 2. INO80
  3. INO80 complex ATPase su…
  4. 0.996
  5. PPI
- 2. SMARCA4
  3. SWI/SNF related, matrix…
  4. 0.995
  5. PPI
- 2. BPTF
  3. bromodomain PHD finger …
  4. 0.995
  5. PPI
- 2. AATF
  3. apoptosis antagonizing …
  4. 0.995
  5. Complex

Subnetwork gene interactions

ENSG00000057935

metastasis associated 1 family member 3

FunCoup

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Ensembl

ENSG00000057935

UniProt

NCBI

57504

GATAD2B

GATA zinc finger domain containing 2B

FunCoup

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Ensembl

ENSG00000143614

UniProt

NCBI

57459

GATAD2A

GATA zinc finger domain containing 2A

FunCoup

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Ensembl

ENSG00000167491

UniProt

NCBI

54815

HDAC2

histone deacetylase 2

FunCoup

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Ensembl

ENSG00000196591

UniProt

NCBI

3066

SMARCAD1

SWI/SNF-related, matrix-associated actin-dependent regulator of chromatin, subfamily a, containing DEAD/H box 1

FunCoup

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Ensembl

ENSG00000163104

UniProt

NCBI

56916

MTA2

metastasis associated 1 family member 2

FunCoup

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Ensembl

ENSG00000149480

UniProt

O94776

NCBI

9219

AATF

apoptosis antagonizing transcription factor

FunCoup

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Ensembl

ENSG00000275700

UniProt

NCBI

26574

RBBP7

RB binding protein 7, chromatin remodeling factor

FunCoup

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Ensembl

ENSG00000102054

UniProt

NCBI

5931

MBD3

methyl-CpG binding domain protein 3

FunCoup

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Ensembl

ENSG00000071655

UniProt

NCBI

53615

MTA1

metastasis associated 1

FunCoup

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Ensembl

ENSG00000182979

UniProt

NCBI

9112

ACTL6A

actin like 6A

FunCoup

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Ensembl

ENSG00000136518

UniProt

NCBI

SIN3A

SIN3 transcription regulator family member A

FunCoup

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Ensembl

ENSG00000169375

UniProt

NCBI

25942

BPTF

bromodomain PHD finger transcription factor

FunCoup

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Ensembl

ENSG00000171634

UniProt

NCBI

2186

RAD21

RAD21 cohesin complex component

FunCoup

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Ensembl

ENSG00000164754

UniProt

NCBI

5885

INO80

INO80 complex ATPase subunit

FunCoup

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Ensembl

ENSG00000128908

UniProt

NCBI

54617

MBD2

methyl-CpG binding domain protein 2

FunCoup

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Ensembl

ENSG00000134046

UniProt

NCBI

8932

CHD3

chromodomain helicase DNA binding protein 3

FunCoup

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Ensembl

ENSG00000170004

UniProt

NCBI

1107

CHD4

chromodomain helicase DNA binding protein 4

FunCoup

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Ensembl

ENSG00000111642

UniProt

NCBI

1108

SMARCA4

SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4

FunCoup

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Ensembl

ENSG00000127616

UniProt

NCBI

6597

CHD5

chromodomain helicase DNA binding protein 5

FunCoup

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Ensembl

ENSG00000116254

UniProt

NCBI

26038

SMARCC1

SWI/SNF related, matrix associated, actin dependent regulator of chromatin subfamily c member 1

FunCoup

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Ensembl

ENSG00000173473

UniProt

NCBI

6599

ARNT

aryl hydrocarbon receptor nuclear translocator

FunCoup

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Ensembl

ENSG00000143437

UniProt

NCBI

HDAC1

histone deacetylase 1

FunCoup

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Ensembl

ENSG00000116478

UniProt

NCBI

3065

KDM1A

lysine demethylase 1A

FunCoup

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Ensembl

ENSG00000004487

UniProt

NCBI

23028

PARP1

poly(ADP-ribose) polymerase 1

FunCoup

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Ensembl

ENSG00000143799

UniProt

NCBI

RBBP4

RB binding protein 4, chromatin remodeling factor

FunCoup

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Ensembl

ENSG00000162521

UniProt

NCBI

5928

RCOR3

REST corepressor 3

FunCoup

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Ensembl

ENSG00000117625

UniProt

NCBI

55758

SMARCC2

SWI/SNF related, matrix associated, actin dependent regulator of chromatin subfamily c member 2

FunCoup

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Ensembl

ENSG00000139613

UniProt

NCBI

6601

FOXK2

forkhead box K2

FunCoup

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Ensembl

ENSG00000141568

UniProt

NCBI

3607

TFAP4

transcription factor AP-4

FunCoup

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Ensembl

ENSG00000090447

UniProt

NCBI

7023

SOX2

SRY-box transcription factor 2

FunCoup

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Ensembl

ENSG00000181449

UniProt

P48431

NCBI

6657

Query genes

		Identifier	Description
30	ENSG00000057935	ENSG00000057935	metastasis associated 1 family member 3
		UniProt	C9JR73 E7EQY4 E7EV10 E9PCS8 E9PF88 F6RRE2 Q9BTC8
		NCBI	57504

Subnetwork genes

		Identifier	Description
26	GATAD2B	ENSG00000143614	GATA zinc finger domain containing 2B
		UniProt	A0A0U1RR30 A0A0U1RR34 A0A0U1RRK3 A0A0U1RRM1 A0A1B0GVS4 A0A1B0GW07 Q8WXI9
		NCBI	57459
26	GATAD2A	ENSG00000167491	GATA zinc finger domain containing 2A
		UniProt	C9JGN4 C9JHD7 C9JJK9 C9JMI3 C9JVY3 H7C3H1 Q86YP4 V9GY85 V9GYX5
		NCBI	54815
26	HDAC2	ENSG00000196591	histone deacetylase 2
		UniProt	E5RFI6 E5RFP9 E5RG37 E5RGV4 E5RH52 E5RHE7 E5RJ04 E5RK19 H3BM24 Q92769
		NCBI	3066
		KEGG signaling	Thyroid hormone signaling pathway Cell cycle Notch signaling pathway
23	SMARCAD1	ENSG00000163104	SWI/SNF-related, matrix-associated actin-dependent regulator of chromatin, subfamily a, containing DEAD/H box 1
		UniProt	D6RAY8 F8W9M2 Q9H4L7
		NCBI	56916
27	MTA2	ENSG00000149480	metastasis associated 1 family member 2
		UniProt	O94776
		NCBI	9219
19	AATF	ENSG00000275700	apoptosis antagonizing transcription factor
		UniProt	A0A087WTH8 A0A087WW41 A0A087WWS8 Q9NY61
		NCBI	26574
27	RBBP7	ENSG00000102054	RB binding protein 7, chromatin remodeling factor
		UniProt	C9J7L0 C9JAJ9 E9PC52 Q16576 Q5JNZ6 Q5JP01 Q5JP02
		NCBI	5931
26	MBD3	ENSG00000071655	methyl-CpG binding domain protein 3
		UniProt	A0A087WT34 A0A087WVG6 A0A087WZ12 A0A087X1H1 A0A0A0MTS6 K7EIE8 O95983
		NCBI	53615
27	MTA1	ENSG00000182979	metastasis associated 1
		UniProt	E7ESY4 F8W9Y9 H0Y4T7 H0YIT0 H7C3F3 Q13330
		NCBI	9112
25	ACTL6A	ENSG00000136518	actin like 6A
		UniProt	C9JQT2 H7C5S0 O96019
		NCBI	86
26	SIN3A	ENSG00000169375	SIN3 transcription regulator family member A
		UniProt	H3BMA2 H3BNA0 H3BNZ3 H3BP90 H3BQ76 H3BQ88 H3BQL7 H3BT34 Q96ST3
		NCBI	25942
		KEGG signaling	Thyroid hormone signaling pathway
22	BPTF	ENSG00000171634	bromodomain PHD finger transcription factor
		UniProt	A0A0A0MR81 A0A2R8Y7Q1 E7ETD6 E9PE19 F5GXF5 F5H176 J3KSK9 J3KSY0 J3QLW4 J3QQK4 J3QQQ8 Q12830
		NCBI	2186
23	RAD21	ENSG00000164754	RAD21 cohesin complex component
		UniProt	E5RFV8 E5RFZ5 E5RG18 E5RI01 E5RIN7 E5RJK5 E5RJW1 O60216
		NCBI	5885
		KEGG signaling	Cell cycle
25	INO80	ENSG00000128908	INO80 complex ATPase subunit
		UniProt	A0A087X0U7 H0YKH3 H0YMN5 H0YNL3 Q9ULG1
		NCBI	54617
24	MBD2	ENSG00000134046	methyl-CpG binding domain protein 2
		UniProt	J3KSA7 Q9UBB5 X6RBL6
		NCBI	8932
25	CHD3	ENSG00000170004	chromodomain helicase DNA binding protein 3
		UniProt	A0A5F9ZHM2 A0A5F9ZHX5 H7C0J3 H7C2H0 H7C3H7 I3L1I4 I3L229 K7EPV1 Q12873
		NCBI	1107
25	CHD4	ENSG00000111642	chromodomain helicase DNA binding protein 4
		UniProt	A0A0C4DGG9 A0A2R8Y212 A0A2R8Y425 A0A2R8Y4X2 A0A2R8Y512 A0A2R8Y521 A0A2R8Y539 A0A2R8Y5J0 A0A2R8Y5M9 A0A2R8Y5Z7 A0A2R8Y685 A0A2R8Y6G9 A0A2R8Y795 A0A2R8Y7I0 A0A2R8Y7M9 A0A2R8Y7X1 A0A2R8Y8B3 A0A2R8Y8C1 A0A2R8YD40 A0A2R8YDJ9 A0A2R8YDW2 A0A2R8YE38 A0A2R8YER1 A0A2R8YFD8 A0A2R8YFK9 A0A2U3TZM0 F5GWX5 F5H596 F5H6N4 Q14839
		NCBI	1108
24	SMARCA4	ENSG00000127616	SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4
		UniProt	A0A0A0MT49 A0A2R8Y440 A0A2R8Y4C5 A0A2R8Y4P4 A0A2R8Y4R6 A0A2R8Y523 A0A2R8Y526 A0A2R8Y583 A0A2R8Y5K3 A0A2R8Y6N0 A0A2R8Y6V2 A0A2R8Y7F3 A0A2R8Y7R0 A0A2R8Y7S2 A0A2R8Y7Y7 A0A2R8Y866 A0A2R8YCY3 A0A2R8YDA1 A0A2R8YF38 A0A2R8YF58 A0A2R8YF80 A0A2R8YFK5 A0A2R8YFV8 A0A2R8YG32 A0A2R8YGG3 A0A2R8YGP5 K7EP28 K7EQF0 P51532 Q9HBD4
		NCBI	6597
18	CHD5	ENSG00000116254	chromodomain helicase DNA binding protein 5
		UniProt	F2Z2R5 F6T542 K7EMC0 K7EMY3 K7ESA5 Q8TDI0
		NCBI	26038
26	SMARCC1	ENSG00000173473	SWI/SNF related, matrix associated, actin dependent regulator of chromatin subfamily c member 1
		UniProt	F8WE13 Q92922
		NCBI	6599
10	ARNT	ENSG00000143437	aryl hydrocarbon receptor nuclear translocator
		UniProt	A6NGV6 D6RDB3 P27540
		NCBI	405
		KEGG signaling	HIF-1 signaling pathway
26	HDAC1	ENSG00000116478	histone deacetylase 1
		UniProt	Q13547 Q5TEE2
		NCBI	3065
		KEGG signaling	Thyroid hormone signaling pathway Cell cycle Notch signaling pathway
25	KDM1A	ENSG00000004487	lysine demethylase 1A
		UniProt	O60341 R4GMP9 R4GMQ1
		NCBI	23028
13	PARP1	ENSG00000143799	poly(ADP-ribose) polymerase 1
		UniProt	P09874 Q5VX84 Q5VX85
		NCBI	142
		KEGG signaling	Apoptosis NF-kappa B signaling pathway
		KEGG metabolic	Base excision repair
26	RBBP4	ENSG00000162521	RB binding protein 4, chromatin remodeling factor
		UniProt	C9JPP3 E9PIC4 E9PND5 E9PNS2 E9PNS6 H0YCT5 H0YDK2 H0YEU5 H0YF10 Q09028
		NCBI	5928
12	RCOR3	ENSG00000117625	REST corepressor 3
		UniProt	B4DV59 E9PPC5 E9PQE5 E9PR63 H0YDD7 H0YDR8 H0YF22 Q9P2K3
		NCBI	55758
25	SMARCC2	ENSG00000139613	SWI/SNF related, matrix associated, actin dependent regulator of chromatin subfamily c member 2
		UniProt	F8VXC8 F8VZW6 Q8TAQ2
		NCBI	6601
7	FOXK2	ENSG00000141568	forkhead box K2
		UniProt	E9PM37 E9PPI7 I3L4U8 Q01167
		NCBI	3607
10	TFAP4	ENSG00000090447	transcription factor AP-4
		UniProt	I3L254 I3L301 I3L4L6 Q01664
		NCBI	7023
4	SOX2	ENSG00000181449	SRY-box transcription factor 2
		UniProt	P48431
		NCBI	6657
		KEGG signaling	Hippo signaling pathway

Enrichment analysis

Search for enrichment of pathways or functional gene sets for your subnetwork genes

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	jSquid_subnetworks.xml	320.84 KB
	H.sapiens_subnetwork.tsv	55.48 KB

Species:

Network information:

Filter Results:

Network appearance:

ENSG00000057935

GATAD2B

GATAD2A

HDAC2

SMARCAD1

MTA2

AATF

RBBP7

MBD3

MTA1

ACTL6A

SIN3A

BPTF

RAD21

INO80

MBD2

CHD3

CHD4

SMARCA4

CHD5

SMARCC1

ARNT

HDAC1

KDM1A

PARP1

RBBP4

RCOR3

SMARCC2

FOXK2

TFAP4

SOX2

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