Found 1 of 1 query genes

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Query interactions

Interaction partners
Confidence
Network
MEX
PIN
SCL
PHP
MIR
TFB
PEX
GIN
DOM
QMS
GRG
Evidence types
HSA
MMU
RNO
CFA
GGA
DRE
CIN
DME
CEL
BTA
SCE
ATH
SPO
BSU
ECO
PFA
DDI
SSO
SSC
MJA
OSA
Species
In Gold st.

ID Query gene
ID Query ortholog

Log-likelihood ratio (LLR)
	Highly positive
	Positive
	Zero
	Negative
	Highly negative
Known coupling
	This network
	Other network

2. ENSG00000033030
3. zinc finger CCHC-type c…
- 2. MTREX
  3. Mtr4 exosome RNA helica…
  4. 1.000
  5. PPI
- 2. HNRNPF
  3. heterogeneous nuclear r…
  4. 0.998
  5. PPI
- 2. XPO1
  3. exportin 1
  4. 0.997
  5. PPI
- 2. RBM7
  3. RNA binding motif prote…
  4. 0.997
  5. PPI
- 2. RBM4B
  3. RNA binding motif prote…
  4. 0.997
  5. PPI
- 2. PRPF40A
  3. pre-mRNA processing fac…
  4. 0.997
  5. PPI
- 2. RPA1
  3. replication protein A1
  4. 0.997
  5. PPI
- 2. RNF2
  3. ring finger protein 2
  4. 0.996
  5. PPI
- 2. NCBP1
  3. nuclear cap binding pro…
  4. 0.990
  5. PPI
- 2. RBM14
  3. RNA binding motif prote…
  4. 0.990
  5. Complex
- 2. CUL1
  3. cullin 1
  4. 0.987
  5. Complex
- 2. ZC3H18
  3. zinc finger CCCH-type c…
  4. 0.986
  5. PPI
- 2. DROSHA
  3. drosha ribonuclease III
  4. 0.985
  5. PPI
- 2. CHD4
  3. chromodomain helicase D…
  4. 0.970
  5. PPI
- 2. PPWD1
  3. peptidylprolyl isomeras…
  4. 0.969
  5. Metabolic
- 2. SRRT
  3. serrate, RNA effector m…
  4. 0.965
  5. PPI
- 2. BRCA1
  3. BRCA1 DNA repair associ…
  4. 0.961
  5. PPI
- 2. BMI1
  3. BMI1 proto-oncogene, po…
  4. 0.947
  5. PPI
- 2. SMG1
  3. SMG1 nonsense mediated …
  4. 0.943
  5. Complex
- 2. EXOSC3
  3. exosome component 3
  4. 0.936
  5. PPI
- 2. SGPL1
  3. sphingosine-1-phosphate…
  4. 0.915
  5. Complex
- 2. LUC7L
  3. LUC7 like
  4. 0.908
  5. PPI
- 2. SRSF1
  3. serine and arginine ric…
  4. 0.896
  5. Metabolic
- 2. RBM5
  3. RNA binding motif prote…
  4. 0.896
  5. Metabolic
- 2. C1D
  3. C1D nuclear receptor co…
  4. 0.889
  5. PPI
- 2. FBXW11
  3. F-box and WD repeat dom…
  4. 0.888
  5. Complex
- 2. EXOSC8
  3. exosome component 8
  4. 0.884
  5. PPI
- 2. NCBP2
  3. nuclear cap binding pro…
  4. 0.880
  5. PPI
- 2. DHX15
  3. DEAH-box helicase 15
  4. 0.871
  5. Metabolic
- 2. CDC40
  3. cell division cycle 40
  4. 0.869
  5. Metabolic

Subnetwork gene interactions

ENSG00000033030

zinc finger CCHC-type containing 8

FunCoup

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Ensembl

ENSG00000033030

UniProt

NCBI

55596

MTREX

Mtr4 exosome RNA helicase

FunCoup

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Ensembl

ENSG00000039123

UniProt

NCBI

23517

RBM4B

RNA binding motif protein 4B

FunCoup

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Ensembl

ENSG00000173914

UniProt

NCBI

83759

SRRT

serrate, RNA effector molecule

FunCoup

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Ensembl

ENSG00000087087

UniProt

NCBI

51593

NCBP1

nuclear cap binding protein subunit 1

FunCoup

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Ensembl

ENSG00000136937

UniProt

NCBI

4686

PRPF40A

pre-mRNA processing factor 40 homolog A

FunCoup

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Ensembl

ENSG00000196504

UniProt

NCBI

55660

C1D

C1D nuclear receptor corepressor

FunCoup

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Ensembl

ENSG00000197223

UniProt

NCBI

10438

EXOSC8

exosome component 8

FunCoup

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Ensembl

ENSG00000120699

UniProt

NCBI

11340

RBM5

RNA binding motif protein 5

FunCoup

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Ensembl

ENSG00000003756

UniProt

NCBI

10181

RNF2

ring finger protein 2

FunCoup

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Ensembl

ENSG00000121481

UniProt

NCBI

6045

RBM14

RNA binding motif protein 14

FunCoup

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Ensembl

ENSG00000239306

UniProt

NCBI

SGPL1

sphingosine-1-phosphate lyase 1

FunCoup

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Ensembl

ENSG00000166224

UniProt

NCBI

8879

CDC40

cell division cycle 40

FunCoup

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Ensembl

ENSG00000168438

UniProt

NCBI

51362

ZC3H18

zinc finger CCCH-type containing 18

FunCoup

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Ensembl

ENSG00000158545

UniProt

NCBI

124245

NCBP2

nuclear cap binding protein subunit 2

FunCoup

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Ensembl

ENSG00000114503

UniProt

NCBI

22916

EXOSC3

exosome component 3

FunCoup

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Ensembl

ENSG00000107371

UniProt

Q9NQT5

NCBI

51010

SMG1

SMG1 nonsense mediated mRNA decay associated PI3K related kinase

FunCoup

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Ensembl

ENSG00000157106

UniProt

NCBI

23049

RPA1

replication protein A1

FunCoup

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Ensembl

ENSG00000132383

UniProt

NCBI

6117

BMI1

BMI1 proto-oncogene, polycomb ring finger

FunCoup

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Ensembl

ENSG00000168283

UniProt

NCBI

CHD4

chromodomain helicase DNA binding protein 4

FunCoup

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Ensembl

ENSG00000111642

UniProt

NCBI

1108

XPO1

exportin 1

FunCoup

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Ensembl

ENSG00000082898

UniProt

NCBI

7514

CUL1

cullin 1

FunCoup

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Ensembl

ENSG00000055130

UniProt

NCBI

8454

RBM7

RNA binding motif protein 7

FunCoup

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Ensembl

ENSG00000076053

UniProt

NCBI

10179

PPWD1

peptidylprolyl isomerase domain and WD repeat containing 1

FunCoup

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Ensembl

ENSG00000113593

UniProt

NCBI

23398

HNRNPF

heterogeneous nuclear ribonucleoprotein F

FunCoup

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Ensembl

ENSG00000169813

UniProt

NCBI

3185

SRSF1

serine and arginine rich splicing factor 1

FunCoup

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Ensembl

ENSG00000136450

UniProt

NCBI

6426

DHX15

DEAH-box helicase 15

FunCoup

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Ensembl

ENSG00000109606

UniProt

O43143

NCBI

1665

FBXW11

F-box and WD repeat domain containing 11

FunCoup

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Ensembl

ENSG00000072803

UniProt

NCBI

23291

BRCA1

BRCA1 DNA repair associated

FunCoup

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Ensembl

ENSG00000012048

UniProt

NCBI

LUC7L

LUC7 like

FunCoup

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Ensembl

ENSG00000007392

UniProt

NCBI

55692

DROSHA

drosha ribonuclease III

FunCoup

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Ensembl

ENSG00000113360

UniProt

NCBI

29102

Query genes

		Identifier	Description
30	ENSG00000033030	ENSG00000033030	zinc finger CCHC-type containing 8
		UniProt	F5GX80 F5GYI9 F5H6J5 Q6NZY4
		NCBI	55596

Subnetwork genes

		Identifier	Description
25	MTREX	ENSG00000039123	Mtr4 exosome RNA helicase
		UniProt	D6REC7 H0Y8U3 H0YAC4 P42285
		NCBI	23517
		KEGG metabolic	RNA degradation
12	RBM4B	ENSG00000173914	RNA binding motif protein 4B
		UniProt	E9PLB0 E9PM61 H0YDG8 Q9BQ04 U3KQD5
		NCBI	83759
25	SRRT	ENSG00000087087	serrate, RNA effector molecule
		UniProt	A0A087X0F4 A0A0A0MSP6 A0A286YEP7 C9JUL9 H7C0U8 H7C1K0 H7C3A1 Q9BXP5
		NCBI	51593
22	NCBP1	ENSG00000136937	nuclear cap binding protein subunit 1
		UniProt	F2Z2T1 Q09161 X6R941
		NCBI	4686
		KEGG metabolic	Spliceosome RNA transport mRNA surveillance pathway
21	PRPF40A	ENSG00000196504	pre-mRNA processing factor 40 homolog A
		UniProt	A0A3F2YNY6 F5H578 H0YG38 H7BXZ7 H7C2N3 O75400
		NCBI	55660
		KEGG metabolic	Spliceosome
15	C1D	ENSG00000197223	C1D nuclear receptor corepressor
		UniProt	J3KPZ4 Q13901
		NCBI	10438
		KEGG metabolic	RNA degradation
17	EXOSC8	ENSG00000120699	exosome component 8
		UniProt	H7C581 H7C5Z2 Q96B26
		NCBI	11340
		KEGG metabolic	RNA degradation
21	RBM5	ENSG00000003756	RNA binding motif protein 5
		UniProt	C9J9P7 C9JFQ5 C9JR02 F8W910 F8WE23 H7BYM9 P52756
		NCBI	10181
13	RNF2	ENSG00000121481	ring finger protein 2
		UniProt	Q99496 X6RFN3
		NCBI	6045
15	RBM14	ENSG00000239306	RNA binding motif protein 14
		UniProt	B8ZZ74 F8WDX3 Q96PK6
		NCBI	100526737 10432
10	SGPL1	ENSG00000166224	sphingosine-1-phosphate lyase 1
		UniProt	H0Y3V8 H7BXL7 O95470
		NCBI	8879
		KEGG signaling	Sphingolipid signaling pathway
		KEGG metabolic	Sphingolipid metabolism
21	CDC40	ENSG00000168438	cell division cycle 40
		UniProt	O60508 Q5SRN1
		NCBI	51362
		KEGG metabolic	Spliceosome
14	ZC3H18	ENSG00000158545	zinc finger CCCH-type containing 18
		UniProt	E7ERS3 H3BP01 H3BPD0 H3BRH3 H3BRN6 Q86VM9
		NCBI	124245
21	NCBP2	ENSG00000114503	nuclear cap binding protein subunit 2
		UniProt	B3KSB0 C9JKF4 C9JQX9 F8WE41 P52298
		NCBI	22916
		KEGG metabolic	Spliceosome RNA transport mRNA surveillance pathway
17	EXOSC3	ENSG00000107371	exosome component 3
		UniProt	Q9NQT5
		NCBI	51010
		KEGG metabolic	RNA degradation
8	SMG1	ENSG00000157106	SMG1 nonsense mediated mRNA decay associated PI3K related kinase
		UniProt	A0A087WXM7 A0A087X1K8 E9PNP6 H3BPS6 H3BQN7 H3BR09 I3L0W2 I3L144 I3L400 J3KRA9 Q96Q15
		NCBI	23049
		KEGG metabolic	mRNA surveillance pathway
22	RPA1	ENSG00000132383	replication protein A1
		UniProt	I3L2M5 I3L4R8 I3L524 P27694
		NCBI	6117
		KEGG metabolic	DNA replication Fanconi anemia pathway Homologous recombination Mismatch repair Nucleotide excision repair
9	BMI1	ENSG00000168283	BMI1 proto-oncogene, polycomb ring finger
		UniProt	P35226 Q5T8Z2 Q5T8Z4 Q5T8Z6
		NCBI	100532731 648
16	CHD4	ENSG00000111642	chromodomain helicase DNA binding protein 4
		UniProt	A0A0C4DGG9 A0A2R8Y212 A0A2R8Y425 A0A2R8Y4X2 A0A2R8Y512 A0A2R8Y521 A0A2R8Y539 A0A2R8Y5J0 A0A2R8Y5M9 A0A2R8Y5Z7 A0A2R8Y685 A0A2R8Y6G9 A0A2R8Y795 A0A2R8Y7I0 A0A2R8Y7M9 A0A2R8Y7X1 A0A2R8Y8B3 A0A2R8Y8C1 A0A2R8YD40 A0A2R8YDJ9 A0A2R8YDW2 A0A2R8YE38 A0A2R8YER1 A0A2R8YFD8 A0A2R8YFK9 A0A2U3TZM0 F5GWX5 F5H596 F5H6N4 Q14839
		NCBI	1108
23	XPO1	ENSG00000082898	exportin 1
		UniProt	C9IYM2 C9IZS4 C9J673 C9JF49 C9JKM9 C9JQ02 C9JV99 F8WF71 H7BZC5 O14980
		NCBI	7514
		KEGG metabolic	Ribosome biogenesis in eukaryotes RNA transport
17	CUL1	ENSG00000055130	cullin 1
		UniProt	A0A0C4DGX4 A0A590UJ21 A0A590UJ50 A0A590UJ56 A0A590UJ59 A0A590UJ97 A0A590UJA0 A0A590UJC4 A0A590UJM8 A0A590UJR3 A0A590UK34 Q13616
		NCBI	8454
		KEGG signaling	Oocyte meiosis Wnt signaling pathway Cell cycle Hedgehog signaling pathway TGF-beta signaling pathway
		KEGG metabolic	Ubiquitin mediated proteolysis Protein processing in endoplasmic reticulum
17	RBM7	ENSG00000076053	RNA binding motif protein 7
		UniProt	F5GXV8 F5GY08 F5H606 F5H674 G3V1T9 J3KPD3 Q9Y580
		NCBI	10179
21	PPWD1	ENSG00000113593	peptidylprolyl isomerase domain and WD repeat containing 1
		UniProt	D6R9Q1 D6RA12 D6RB19 D6RD43 D6RDA4 D6RHV0 F5H7P7 H0Y8N5 Q96BP3
		NCBI	23398
20	HNRNPF	ENSG00000169813	heterogeneous nuclear ribonucleoprotein F
		UniProt	A0A1B0GW42 P52597
		NCBI	3185
18	SRSF1	ENSG00000136450	serine and arginine rich splicing factor 1
		UniProt	J3KSR8 J3KSW7 J3KTL2 J3QQV5 Q07955
		NCBI	6426
		KEGG signaling	IL-17 signaling pathway
		KEGG metabolic	Spliceosome
25	DHX15	ENSG00000109606	DEAH-box helicase 15
		UniProt	O43143
		NCBI	1665
		KEGG metabolic	Spliceosome
8	FBXW11	ENSG00000072803	F-box and WD repeat domain containing 11
		UniProt	E5RG78 E5RGC1 E5RH92 Q9UKB1
		NCBI	23291
		KEGG signaling	Oocyte meiosis Wnt signaling pathway Hedgehog signaling pathway Hippo signaling pathway
		KEGG metabolic	Ubiquitin mediated proteolysis
3	BRCA1	ENSG00000012048	BRCA1 DNA repair associated
		UniProt	A0A0A0MSN1 A0A0U1RRA9 A0A2R8Y587 A0A2R8Y6Y9 A0A2R8Y7V5 A0A494C182 B7ZA85 C6YB45 C9IZW4 E7ENB7 E7EQW4 E7EUM2 E7EWN5 E9PC22 E9PH68 G1UI37 H0Y850 H0Y881 H0Y8B8 H0Y8D8 K7EJW3 K7EPC7 P38398 Q3B891 Q5YLB2
		NCBI	672
		KEGG signaling	PI3K-Akt signaling pathway
		KEGG metabolic	Fanconi anemia pathway Ubiquitin mediated proteolysis Homologous recombination
11	LUC7L	ENSG00000007392	LUC7 like
		UniProt	A8MYV2 B8ZZ08 B8ZZ09 B8ZZ10 B8ZZ12 F2Z322 F8WBC1 H7C2U4 Q9NQ29
		NCBI	55692
7	DROSHA	ENSG00000113360	drosha ribonuclease III
		UniProt	E5RHD1 H0YB67 H7C5U6 Q9NRR4
		NCBI	29102
		KEGG metabolic	Ribosome biogenesis in eukaryotes

Enrichment analysis

Search for enrichment of pathways or functional gene sets for your subnetwork genes

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	jSquid_subnetworks.xml	307.58 KB
	H.sapiens_subnetwork.tsv	45.33 KB

Species:

Network information:

Filter Results:

Network appearance:

ENSG00000033030

MTREX

RBM4B

SRRT

NCBP1

PRPF40A

C1D

EXOSC8

RBM5

RNF2

RBM14

SGPL1

CDC40

ZC3H18

NCBP2

EXOSC3

SMG1

RPA1

BMI1

CHD4

XPO1

CUL1

RBM7

PPWD1

HNRNPF

SRSF1

DHX15

FBXW11

BRCA1

LUC7L

DROSHA

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