Found 1 of 1 query genes

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Query interactions

Interaction partners
Confidence
Network
MEX
PIN
SCL
PHP
MIR
TFB
PEX
GIN
DOM
QMS
GRG
Evidence types
HSA
MMU
RNO
CFA
GGA
DRE
CIN
DME
CEL
BTA
SCE
ATH
SPO
BSU
ECO
PFA
DDI
SSO
SSC
MJA
OSA
Species
In Gold st.

ID Query gene
ID Query ortholog

Log-likelihood ratio (LLR)
	Highly positive
	Positive
	Zero
	Negative
	Highly negative
Known coupling
	This network
	Other network

2. ENSG00000005379
3. TSPO associated protein…
- 2. CADPS2
  3. calcium dependent secre…
  4. 0.994
  5. PPI
- 2. GPRASP2
  3. G protein-coupled recep…
  4. 0.954
  5. PPI
- 2. UNC13C
  3. unc-13 homolog C
  4. 0.917
  5. PPI
- 2. SYN1
  3. synapsin I
  4. 0.908
  5. PPI
- 2. CACNA1A
  3. calcium voltage-gated c…
  4. 0.906
  5. PPI
- 2. SLC8A2
  3. solute carrier family 8…
  4. 0.899
  5. Metabolic
- 2. STXBP1
  3. syntaxin binding protei…
  4. 0.855
  5. Metabolic
- 2. NCS1
  3. neuronal calcium sensor…
  4. 0.785
  5. Metabolic
- 2. BRSK1
  3. BR serine/threonine kin…
  4. 0.733
  5. Metabolic
- 2. GLRA1
  3. glycine receptor alpha 1
  4. 0.708
  5. PPI
- 2. UNC13A
  3. unc-13 homolog A
  4. 0.699
  5. Metabolic
- 2. SLC4A10
  3. solute carrier family 4…
  4. 0.667
  5. Metabolic
- 2. ADGRL1
  3. adhesion G protein-coup…
  4. 0.667
  5. Metabolic
- 2. KCNA3
  3. potassium voltage-gated…
  4. 0.647
  5. Metabolic
- 2. SV2A
  3. synaptic vesicle glycop…
  4. 0.601
  5. Metabolic
- 2. UNC13B
  3. unc-13 homolog B
  4. 0.578
  5. Metabolic
- 2. CHRM3
  3. cholinergic receptor mu…
  4. 0.576
  5. Metabolic
- 2. GRM3
  3. glutamate metabotropic …
  4. 0.551
  5. Metabolic
- 2. KCNA1
  3. potassium voltage-gated…
  4. 0.549
  5. Metabolic
- 2. SLC8A3
  3. solute carrier family 8…
  4. 0.544
  5. Metabolic
- 2. ARNT2
  3. aryl hydrocarbon recept…
  4. 0.542
  5. PPI
- 2. PACSIN1
  3. protein kinase C and ca…
  4. 0.542
  5. Metabolic
- 2. KCNAB2
  3. potassium voltage-gated…
  4. 0.537
  5. Complex
- 2. SYN3
  3. synapsin III
  4. 0.533
  5. PPI
- 2. KCNC1
  3. potassium voltage-gated…
  4. 0.512
  5. Metabolic
- 2. KCNA2
  3. potassium voltage-gated…
  4. 0.502
  5. Metabolic
- 2. SLC8A1
  3. solute carrier family 8…
  4. 0.493
  5. Metabolic
- 2. PTPRN
  3. protein tyrosine phosph…
  4. 0.483
  5. Metabolic
- 2. GAD1
  3. glutamate decarboxylase…
  4. 0.446
  5. Metabolic
- 2. PRKCB
  3. protein kinase C beta
  4. 0.440
  5. Metabolic

Subnetwork gene interactions

ENSG00000005379

TSPO associated protein 1

FunCoup

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Ensembl

ENSG00000005379

UniProt

NCBI

9256

STXBP1

syntaxin binding protein 1

FunCoup

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Ensembl

ENSG00000136854

UniProt

NCBI

6812

KCNC1

potassium voltage-gated channel subfamily C member 1

FunCoup

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Ensembl

ENSG00000129159

UniProt

NCBI

3746

UNC13B

unc-13 homolog B

FunCoup

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Ensembl

ENSG00000198722

UniProt

NCBI

10497

KCNA3

potassium voltage-gated channel subfamily A member 3

FunCoup

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Ensembl

ENSG00000177272

UniProt

P22001

NCBI

3738

NCS1

neuronal calcium sensor 1

FunCoup

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Ensembl

ENSG00000107130

UniProt

P62166

NCBI

23413

KCNA1

potassium voltage-gated channel subfamily A member 1

FunCoup

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Ensembl

ENSG00000111262

UniProt

NCBI

3736

PRKCB

protein kinase C beta

FunCoup

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Ensembl

ENSG00000166501

UniProt

NCBI

5579

PACSIN1

protein kinase C and casein kinase substrate in neurons 1

FunCoup

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Ensembl

ENSG00000124507

UniProt

NCBI

29993

KCNA2

potassium voltage-gated channel subfamily A member 2

FunCoup

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Ensembl

ENSG00000177301

UniProt

NCBI

3737

SYN1

synapsin I

FunCoup

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Ensembl

ENSG00000008056

UniProt

NCBI

6853

GRM3

glutamate metabotropic receptor 3

FunCoup

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Ensembl

ENSG00000198822

UniProt

NCBI

2913

UNC13C

unc-13 homolog C

FunCoup

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Ensembl

ENSG00000137766

UniProt

NCBI

440279

SLC4A10

solute carrier family 4 member 10

FunCoup

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Ensembl

ENSG00000144290

UniProt

NCBI

57282

UNC13A

unc-13 homolog A

FunCoup

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Ensembl

ENSG00000130477

UniProt

NCBI

23025

PTPRN

protein tyrosine phosphatase receptor type N

FunCoup

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Ensembl

ENSG00000054356

UniProt

NCBI

5798

GLRA1

glycine receptor alpha 1

FunCoup

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Ensembl

ENSG00000145888

UniProt

NCBI

2741

CADPS2

calcium dependent secretion activator 2

FunCoup

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Ensembl

ENSG00000081803

UniProt

NCBI

93664

CACNA1A

calcium voltage-gated channel subunit alpha1 A

FunCoup

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Ensembl

ENSG00000141837

UniProt

NCBI

GAD1

glutamate decarboxylase 1

FunCoup

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Ensembl

ENSG00000128683

UniProt

NCBI

2571

KCNAB2

potassium voltage-gated channel subfamily A regulatory beta subunit 2

FunCoup

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Ensembl

ENSG00000069424

UniProt

NCBI

8514

ADGRL1

adhesion G protein-coupled receptor L1

FunCoup

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Ensembl

ENSG00000072071

UniProt

NCBI

22859

CHRM3

cholinergic receptor muscarinic 3

FunCoup

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Ensembl

ENSG00000133019

UniProt

NCBI

1131

SLC8A2

solute carrier family 8 member A2

FunCoup

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Ensembl

ENSG00000118160

UniProt

NCBI

6543

BRSK1

BR serine/threonine kinase 1

FunCoup

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Ensembl

ENSG00000160469

UniProt

NCBI

84446

SV2A

synaptic vesicle glycoprotein 2A

FunCoup

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Ensembl

ENSG00000159164

UniProt

Q7L0J3

NCBI

9900

SLC8A1

solute carrier family 8 member A1

FunCoup

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Ensembl

ENSG00000183023

UniProt

NCBI

6546

SLC8A3

solute carrier family 8 member A3

FunCoup

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Ensembl

ENSG00000100678

UniProt

NCBI

6547

GPRASP2

G protein-coupled receptor associated sorting protein 2

FunCoup

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Ensembl

ENSG00000158301

UniProt

Q96D09

NCBI

SYN3

synapsin III

FunCoup

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Ensembl

ENSG00000185666

UniProt

NCBI

8224

ARNT2

aryl hydrocarbon receptor nuclear translocator 2

FunCoup

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Ensembl

ENSG00000172379

UniProt

NCBI

9915

Query genes

		Identifier	Description
30	ENSG00000005379	ENSG00000005379	TSPO associated protein 1
		UniProt	A0A0C4DGN5 J3KSY4 J3KT64 O95153
		NCBI	9256

Subnetwork genes

		Identifier	Description
14	STXBP1	ENSG00000136854	syntaxin binding protein 1
		UniProt	A0A096LP33 A0A096LP52 A0A0D9SEH5 A0A0D9SEP9 A0A0D9SFQ7 A0A0D9SFW6 A0A0D9SG72 A0A1B0GTD8 A0A1B0GTP9 A0A1B0GUQ2 A0A1B0GVQ5 A0A1B0GVV9 A0A1B0GW76 A0A1B0GWF2 A0A2R8Y5D4 P61764
		NCBI	6812
		KEGG signaling	Synaptic vesicle cycle
11	KCNC1	ENSG00000129159	potassium voltage-gated channel subfamily C member 1
		UniProt	A0A1W2PNN0 A0A1W2PNZ3 A0A1W2PP60 A0A1W2PPN9 A0A1W2PPT0 A0A1W2PPX0 A0A1W2PRL7 P48547
		NCBI	3746
8	UNC13B	ENSG00000198722	unc-13 homolog B
		UniProt	A0A0U1RRB5 A0A0U1RRL2 A0A1B0GUS7 A0A1B0GVW8 B1AM27 F8W8M9 I6L9J0 O14795
		NCBI	10497
		KEGG signaling	Synaptic vesicle cycle
9	KCNA3	ENSG00000177272	potassium voltage-gated channel subfamily A member 3
		UniProt	P22001
		NCBI	3738
12	NCS1	ENSG00000107130	neuronal calcium sensor 1
		UniProt	P62166
		NCBI	23413
13	KCNA1	ENSG00000111262	potassium voltage-gated channel subfamily A member 1
		UniProt	A0A1W2PQM4 A0A1W2PRI2 Q09470
		NCBI	3736
14	PRKCB	ENSG00000166501	protein kinase C beta
		UniProt	H3BV73 I3L148 I3L1Z0 P05771
		NCBI	5579
		KEGG signaling	Thyroid hormone signaling pathway Calcium signaling pathway NF-kappa B signaling pathway Chemokine signaling pathway Fc gamma R-mediated phagocytosis Long-term potentiation B cell receptor signaling pathway Gap junction HIF-1 signaling pathway Dopaminergic synapse GABAergic synapse Serotonergic synapse Cholinergic synapse Glutamatergic synapse Oxytocin signaling pathway Retrograde endocannabinoid signaling Leukocyte transendothelial migration MAPK signaling pathway VEGF signaling pathway mTOR signaling pathway Vascular smooth muscle contraction Sphingolipid signaling pathway Phosphatidylinositol signaling system Rap1 signaling pathway Long-term depression Focal adhesion Ras signaling pathway Wnt signaling pathway ErbB signaling pathway Natural killer cell mediated cytotoxicity Melanogenesis GnRH signaling pathway
		KEGG metabolic	Carbohydrate digestion and absorption
3	PACSIN1	ENSG00000124507	protein kinase C and casein kinase substrate in neurons 1
		UniProt	F6U236 Q9BY11
		NCBI	29993
12	KCNA2	ENSG00000177301	potassium voltage-gated channel subfamily A member 2
		UniProt	A0A1W2PP65 A0A1W2PPM7 A0A1W2PPN8 A0A1W2PR01 A0A1W2PRY2 P16389
		NCBI	3737
12	SYN1	ENSG00000008056	synapsin I
		UniProt	A0A1W2PS00 A0A1W2PSE9 P17600
		NCBI	6853
12	GRM3	ENSG00000198822	glutamate metabotropic receptor 3
		UniProt	C9J2I2 C9JIT1 C9JUH9 Q14832
		NCBI	2913
		KEGG signaling	Phospholipase D signaling pathway Glutamatergic synapse Neuroactive ligand-receptor interaction
19	UNC13C	ENSG00000137766	unc-13 homolog C
		UniProt	A0A0C4DGH4 A0A3B3ISZ1 H0YL13 H3BRP8 Q8NB66
		NCBI	440279
		KEGG signaling	Synaptic vesicle cycle
7	SLC4A10	ENSG00000144290	solute carrier family 4 member 10
		UniProt	C9J240 E7EW28 F8WDX9 Q6U841
		NCBI	57282
15	UNC13A	ENSG00000130477	unc-13 homolog A
		UniProt	F8VZH8 F8W059 F8W0P6 Q9UPW8
		NCBI	23025
		KEGG signaling	Synaptic vesicle cycle
4	PTPRN	ENSG00000054356	protein tyrosine phosphatase receptor type N
		UniProt	A0A1B0GX26 C9J392 C9JCQ0 C9JJL7 C9JR27 H7C0U9 Q16849 U3KQ66
		NCBI	5798
9	GLRA1	ENSG00000145888	glycine receptor alpha 1
		UniProt	E5RJ70 P23415
		NCBI	2741
		KEGG signaling	Neuroactive ligand-receptor interaction
6	CADPS2	ENSG00000081803	calcium dependent secretion activator 2
		UniProt	A0A087X1P3 C9IYE1 F8W8P5 H0Y8B5 H7BYR4 Q86UW7
		NCBI	93664
8	CACNA1A	ENSG00000141837	calcium voltage-gated channel subunit alpha1 A
		UniProt	A0A087WW63 A0A1B0GTG6 A0A1B0GTI4 A0A1B0GTN7 A0A1B0GTW2 A0A1B0GU74 A0A1B0GU81 A0A1B0GUE5 A0A1B0GUM7 A0A1B0GUP3 A0A1B0GUS3 A0A1B0GVD8 A0A1B0GVX1 A0A1C7CYY9 A0A384DVW2 A0A590UJK2 B5TYJ1 I3L2V5 I3L391 K7EIF8 K7EKF7 K7EQ95 O00555
		NCBI	773
		KEGG signaling	Synaptic vesicle cycle Taste transduction Long-term depression MAPK signaling pathway Calcium signaling pathway Dopaminergic synapse GABAergic synapse Serotonergic synapse Cholinergic synapse Glutamatergic synapse Retrograde endocannabinoid signaling
5	GAD1	ENSG00000128683	glutamate decarboxylase 1
		UniProt	C9J6C9 C9JLZ7 C9JN45 C9JT43 F8WD43 Q99259 U3KQR2
		NCBI	2571
		KEGG signaling	GABAergic synapse
		KEGG metabolic	Alanine, aspartate and glutamate metabolism Butanoate metabolism Taurine and hypotaurine metabolism beta-Alanine metabolism
11	KCNAB2	ENSG00000069424	potassium voltage-gated channel subfamily A regulatory beta subunit 2
		UniProt	A0A590UJ15 A0A590UJ35 A0A590UJ72 A0A590UJ79 A0A590UJB6 A0A590UJB8 A0A590UJI8 A0A590UJJ4 A0A590UJK5 A0A590UJU1 A0A590UJU4 A0A590UJV4 A0A590UJX9 A0A590UJY1 A0A590UK89 A0A5F9UN28 K7EIR5 K7EKU4 Q13303 Q5TG78 Q5TG81 Q5TG84
		NCBI	8514
4	ADGRL1	ENSG00000072071	adhesion G protein-coupled receptor L1
		UniProt	K7EK47 K7ERC3 K7ESH3 O94910
		NCBI	22859
2	CHRM3	ENSG00000133019	cholinergic receptor muscarinic 3
		UniProt	B1AN12 P20309
		NCBI	1131
		KEGG signaling	Taste transduction Calcium signaling pathway Cholinergic synapse Neuroactive ligand-receptor interaction
4	SLC8A2	ENSG00000118160	solute carrier family 8 member A2
		UniProt	F5H6L7 M0R1Z4 M0R211 Q9UPR5
		NCBI	6543
		KEGG signaling	Olfactory transduction cGMP-PKG signaling pathway Calcium signaling pathway Apelin signaling pathway Adrenergic signaling in cardiomyocytes Cardiac muscle contraction
		KEGG metabolic	Protein digestion and absorption
9	BRSK1	ENSG00000160469	BR serine/threonine kinase 1
		UniProt	J3KNK0 K7EM68 K7EN26 Q8TDC3
		NCBI	84446
9	SV2A	ENSG00000159164	synaptic vesicle glycoprotein 2A
		UniProt	Q7L0J3
		NCBI	9900
		KEGG signaling	ECM-receptor interaction
1	SLC8A1	ENSG00000183023	solute carrier family 8 member A1
		UniProt	E7EV41 E9PB98 E9PCL8 P32418
		NCBI	6546
		KEGG signaling	Olfactory transduction cGMP-PKG signaling pathway Calcium signaling pathway Apelin signaling pathway Adrenergic signaling in cardiomyocytes Cardiac muscle contraction
		KEGG metabolic	Protein digestion and absorption
3	SLC8A3	ENSG00000100678	solute carrier family 8 member A3
		UniProt	F2Z391 P57103
		NCBI	6547
		KEGG signaling	Olfactory transduction cGMP-PKG signaling pathway Calcium signaling pathway Apelin signaling pathway Adrenergic signaling in cardiomyocytes Cardiac muscle contraction
		KEGG metabolic	Protein digestion and absorption
1	GPRASP2	ENSG00000158301	G protein-coupled receptor associated sorting protein 2
		UniProt	Q96D09
		NCBI	100528062 114928
5	SYN3	ENSG00000185666	synapsin III
		UniProt	A0A087WTG8 A0A0A0MR68 A6ZJ82 O14994 Q4TT46
		NCBI	8224
2	ARNT2	ENSG00000172379	aryl hydrocarbon receptor nuclear translocator 2
		UniProt	A0A087WVE9 H0YKW1 Q9HBZ2
		NCBI	9915

Enrichment analysis

Search for enrichment of pathways or functional gene sets for your subnetwork genes

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	jSquid_subnetworks.xml	225.33 KB
	H.sapiens_subnetwork.tsv	21.82 KB

Species:

Network information:

Filter Results:

Network appearance:

ENSG00000005379

STXBP1

KCNC1

UNC13B

KCNA3

NCS1

KCNA1

PRKCB

PACSIN1

KCNA2

SYN1

GRM3

UNC13C

SLC4A10

UNC13A

PTPRN

GLRA1

CADPS2

CACNA1A

GAD1

KCNAB2

ADGRL1

CHRM3

SLC8A2

BRSK1

SV2A

SLC8A1

SLC8A3

GPRASP2

SYN3

ARNT2

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